ORBIMED ADVISORS LLC Insider Trading Activity

According to the SEC Form 4 filings, ORBIMED ADVISORS LLC, being in a position of

1. 10 percent owner at Adicet Bio, Inc.,
   оver the last 12 months, has bought 5000000 shares for $5M, and sold 0 shares,
   over all time since 2018-01-30, has bought 10066666 shares for $30.33M, and sold 0 shares.
2. at Compass Therapeutics, Inc.,
   оver the last 12 months, has bought 0 shares, and sold 3571428 shares for $5.68M,
   over all time since 2020-06-19, has bought 7214275 shares for $27.32M, and sold 3571428 shares for $5.68M.
3. at Corvus Pharmaceuticals, Inc.,
   оver the last 12 months, has bought 0 shares, and sold 1176332 shares for $4.89M,
   over all time since 2016-03-29, has bought 3966364 shares for $31.4M, and sold 2285976 shares for $11.65M.
4. director at Disc Medicine, Inc.,
   оver the last 12 months, has bought 0 shares, and sold 370551 share for $20.11M,
   over all time since 2024-06-17, has bought 83334 shares for $3M, and sold 370551 share for $20.11M.
5. at Edgewise Therapeutics, Inc.,
   оver the last 12 months, has bought 496771 share for $10M, and sold 0 shares,
   over all time since 2021-03-30, has bought 2292562 shares for $32.49M, and sold 0 shares.
6. 10 percent owner at NeuroPace, Inc.,
   оver the last 12 months, has bought 0 shares, and sold 168136 shares for $2.67M,
   over all time since 2021-04-21, has bought 235000 shares for $4M, and sold 774082 shares for $11.35M.
7. 10 percent owner at Passage Bio, Inc.,
   оver the last 12 months, has bought 0 shares, and sold 968283 shares for $325,674,
   over all time since 2020-02-28, has bought 2308277 shares for $16.44M, and sold 1967657 shares for $1.01M.
8. 10 percent owner at PMV Pharmaceuticals, Inc.,
   оver the last 12 months, has bought 0 shares, and sold 500000 shares for $900,000,
   over all time since 2020-09-25, has bought 950000 shares for $17.1M, and sold 587786 shares for $1.1M.
9. director at Shattuck Labs, Inc.,
   оver the last 12 months, has bought 6306127 shares for $5.47M, and sold 0 shares,
   over all time since 2025-08-25, has bought 6306127 shares for $5.47M, and sold 0 shares.
10. director at Sionna Therapeutics, Inc.,
    оver the last 12 months, has bought 0 shares, and sold 143304 shares for $6.38M,
    over all time since 2025-11-24, has bought 0 shares, and sold 143304 shares for $6.38M.
11. 10 percent owner at Xtant Medical Holdings, Inc.,
    оver the last 12 months, has bought 0 shares, and sold 17109618 shares for $7.19M,
    over all time since 2018-02-14, has bought 945819 shares for $6.81M, and sold 17109618 shares for $7.19M.

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