| 2004-12-09 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 2,000 0.0035% | $6.05 | $12,100 | -23.03% | |
| 2004-12-08 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 1,000 0.0017% | $5.85 | $5,850 | -20.27% | |
| 2004-12-07 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 1,000 0.0017% | $5.85 | $5,850 | -19.73% | |
| 2004-12-06 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 5,000 0.0055% | $3.75 | $18,750 | -21.34% | |
| 2004-12-03 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 5,000 0.0055% | $3.75 | $18,750 | -21.43% | |
| 2004-12-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 12,304 0.0194% | $5.45 | $67,090 | -22.13% | |
| 2004-12-01 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 5,000 0.0066% | $3.75 | $18,750 | -4.88% | |
| 2004-01-21 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 20,000 0.0159% | $3.75 | $75,000 | -29.91% |