| 2024-02-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Scientific Officer | 1,853 0.0012% | $49.52 | $91,752 | -15.01% | |
| 2024-01-17 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Scientific Officer | 6,745 0.0046% | $50.42 | $340,063 | -16.33% | |
| 2023-12-21 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Scientific Officer | 16,113 0.0113% | $49.29 | $794,211 | -11.92% | |
| 2023-12-20 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Scientific Officer | 6,500 0.0046% | $49.64 | $322,643 | -11.22% | |
| 2023-12-14 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Scientific Officer | 22,612 0.0157% | $49.58 | $1.12M | -12.95% | |
| 2023-09-28 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Scientific Officer | 4,460 0.0031% | $46.50 | $207,390 | -2.12% | |
| 2023-02-06 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Scientific Officer | 1,813 0.0013% | $40.57 | $73,560 | +1.91% | |
| 2023-01-18 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Scientific Officer | 6,978 0.0048% | $38.89 | $271,356 | +2.81% | |
| 2020-12-04 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Scientific Officer | 7,947 0.0057% | $51.04 | $405,615 | -24.11% | |
| 2020-12-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Scientific Officer | 7,053 0.005% | $51.32 | $361,960 | -24.16% | |
| 2020-11-03 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Scientific Officer | 15,000 0.0107% | $46.77 | $701,600 | -14.86% | |
| 2020-06-25 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Scientific Officer | 15,000 0.0105% | $59.77 | $896,505 | -16.06% | |
| 2019-02-01 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Antisense Research | 18,026 0.0081% | $36.49 | $657,769 | +9.54% | |
| 2018-11-01 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Antisense Research | 25,000 0.0117% | $32.11 | $802,870 | +23.05% | |
| 2018-08-08 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Antisense Research | 12,500 0.0086% | $44.96 | $562,009 | +28.88% | |
| 2018-05-11 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Antisense Research | 25,000 0.011% | $26.13 | $653,125 | +12.35% | |
| 2018-02-01 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Antisense Research | 25,000 0.0113% | $29.88 | $746,885 | -8.92% | |
| 2018-01-16 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Antisense Research | 5,392 0.0044% | $51.76 | $279,090 | -5.8% | |
| 2017-10-18 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Antisense Research | 24,500 0.0116% | $37.65 | $922,303 | -23.96% | |
| 2017-07-24 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Antisense Research | 20,000 0.0094% | $34.79 | $695,800 | -14.83% |