| 2008-09-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 10,000 0.004% | $6.81 | $68,100 | -15.72% | |
| 2008-08-22 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 10,000 0.0038% | $6.81 | $68,100 | -19.51% | |
| 2008-08-11 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 15,000 0.0152% | $18.37 | $275,577 | -21.37% | |
| 2008-04-10 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 5,300 0.0023% | $6.84 | $36,252 | -15.54% | |
| 2008-04-07 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 12,200 0.0131% | $16.06 | $195,946 | -10.08% | |
| 2007-09-18 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 6,000 0.0034% | $6.81 | $40,860 | +8.48% | |
| 2007-09-14 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 24,000 0.0286% | $14.14 | $339,244 | +10.19% | |
| 2006-12-08 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 11,100 0.0076% | $6.81 | $75,591 | -11.34% | |
| 2006-12-04 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 5,000 0.0036% | $6.81 | $34,050 | -5.03% | |
| 2006-11-14 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 3,900 0.0028% | $6.81 | $26,559 | -7.24% | |
| 2006-11-13 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 20,000 0.0261% | $13.36 | $267,200 | -15.53% | |
| 2006-11-10 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 6,788 0.0083% | $10.40 | $70,629 | +1.16% | |
| 2006-11-09 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 20,000 0.0123% | $5.15 | $103,000 | +3.04% | |
| 2006-03-21 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 12,756 0.0182% | $9.03 | $115,147 | -5.39% | |
| 2006-03-20 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 14,032 0.0194% | $9.08 | $127,353 | -9.24% | |
| 2006-02-17 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 26,789 0.0231% | $5.15 | $137,963 | -2.97% | |
| 2004-04-27 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 2,400 0.0044% | $9.02 | $21,638 | -43.69% | |
| 2004-02-11 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 2,582 0.002% | $4.00 | $10,328 | -36.35% | |
| 2004-02-06 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 7,368 0.007% | $4.64 | $34,172 | -33.87% | |
| 2004-02-03 | Sale | Ionis Pharmaceuticals, Inc. IONS | Vice President | 700 0.0013% | $9.03 | $6,318 | -34.57% |