| 2024-02-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Development Officer | 1,961 0.0013% | $50.04 | $98,135 | -15.01% | |
| 2024-01-17 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Development Officer | 7,338 0.005% | $50.42 | $369,960 | -16.33% | |
| 2023-12-21 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Development Officer | 4,112 0.0029% | $49.29 | $202,681 | -11.92% | |
| 2023-12-20 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Development Officer | 6,500 0.0046% | $49.64 | $322,643 | -11.22% | |
| 2023-12-14 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Development Officer | 10,613 0.0074% | $49.58 | $526,236 | -12.95% | |
| 2023-02-06 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Development Officer | 1,920 0.0013% | $40.66 | $78,070 | +1.91% | |
| 2023-01-18 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Development Officer | 7,873 0.0055% | $39.57 | $311,525 | +2.81% | |
| 2021-01-13 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Chief Development Offc | 141 <0.0001% | $59.50 | $8,390 | -37.35% | |
| 2020-11-25 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Development | 11,920 0.0085% | $50.05 | $596,596 | -22.09% | |
| 2020-11-24 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Development | 2,380 0.0017% | $50.83 | $120,975 | -21.66% | |
| 2020-11-23 | Sale | Ionis Pharmaceuticals, Inc. IONS | EVP, Development | 10,700 0.0076% | $50.11 | $536,177 | -21.85% | |
| 2019-12-04 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Development | 10,000 0.0071% | $65.00 | $650,000 | -15.35% | |
| 2019-12-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Development | 5,000 0.0036% | $65.06 | $325,287 | -13.8% | |
| 2019-04-08 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Development | 68,000 0.0401% | $71.07 | $4.83M | -27.2% | |
| 2019-02-13 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Development | 1,998 0.0014% | $60.00 | $119,880 | +5.77% | |
| 2018-01-16 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Development | 5,446 0.0044% | $51.76 | $281,885 | -5.8% | |
| 2017-10-13 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Development | 7,842 0.0064% | $60.00 | $470,520 | -17.19% | |
| 2017-01-17 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Development | 4,882 0.0039% | $46.29 | $225,992 | +8.82% | |
| 2016-01-19 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Development | 4,324 0.0037% | $41.46 | $179,269 | -12.65% | |
| 2015-03-19 | Sale | Ionis Pharmaceuticals, Inc. IONS | SVP, Development | 16,000 0.0078% | $44.85 | $717,552 | -28.48% |