| 2024-02-16 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 387 0.0003% | $44.49 | $17,219 | -5.51% | |
| 2024-02-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 23,501 0.0156% | $49.37 | $1.16M | -15.01% | |
| 2024-01-25 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 2,285 0.0016% | $51.75 | $118,249 | -17.04% | |
| 2024-01-17 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 32,059 0.022% | $50.42 | $1.62M | -16.33% | |
| 2023-12-21 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 17,500 0.0123% | $49.29 | $862,577 | -11.92% | |
| 2023-12-20 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 6,500 0.0046% | $49.64 | $322,643 | -11.22% | |
| 2023-12-14 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 24,000 0.0166% | $49.58 | $1.19M | -12.95% | |
| 2023-10-12 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 3,770 0.0026% | $46.00 | $173,420 | -1.93% | |
| 2023-07-07 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 18,650 0.0132% | $42.25 | $787,953 | +4.04% | |
| 2023-02-06 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 24,651 0.0173% | $40.69 | $1M | +1.91% | |
| 2023-01-18 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 25,066 0.0174% | $39.49 | $989,947 | +2.81% | |
| 2022-04-01 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 355 0.0002% | $37.49 | $13,309 | +1.07% | |
| 2021-03-01 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 236 0.0002% | $54.27 | $12,809 | -32.9% | |
| 2020-12-04 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 23,840 0.017% | $51.04 | $1.22M | -24.11% | |
| 2020-12-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 21,160 0.0151% | $51.32 | $1.09M | -24.16% | |
| 2020-09-01 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 314 0.0002% | $53.70 | $16,862 | -13.57% | |
| 2020-01-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Executive Officer | 173 0.0001% | $60.25 | $10,423 | -11.05% | |
| 2019-11-20 | Sale | Ionis Pharmaceuticals, Inc. IONS | COO & SVP, Translational Med | 5,776 0.0041% | $60.01 | $346,618 | -6.42% | |
| 2019-07-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Operating Officer | 210 0.0002% | $66.40 | $13,944 | -9.79% | |
| 2019-01-02 | Sale | Ionis Pharmaceuticals, Inc. IONS | Chief Operating Officer | 428 0.0003% | $53.50 | $22,898 | +19.11% |