Aileron Therapeutics, Inc. operates as a clinical stage chemoprotection oncology company in the United States. The company is developing ALRN-6924, which is in Phase 1 trial for solid tumor and lymphoma; Phase 2a clinical trial to treat peripheral T-cell lymphoma; Phase I clinical trial for the treatment of acute myeloid leukemia (AML) and advanced myelodysplastic syndrome (MDS); Phase 1b trial to test the combination of ALRN-6924 and cytarabine, or Ara-C, in patients with MDS; and a Phase 2a combination trial of ALRN-6924 and palbociclib in patients with tumors harboring MDM2 amplifications co-amplifications, as well as for patients with p53-mutated small cell lung cancer that has completed Phase 1b clinical trial. It has a license agreement with Dana-Farber Cancer Institute and Harvard College; and Umicore Precious Metals Chemistry USA, LLC. The company was formerly known as Renegade Therapeutics, Inc. and changed its name to Aileron Therapeutics, Inc. in February 2007. Aileron Therapeutics, Inc. was incorporated in 2001 and is based in Boston, Massachusetts.
Over the last 12 months, insiders at Aileron Therapeutics, Inc. have bought $10,745 and sold $281,909 worth of Aileron Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Aileron Therapeutics, Inc. have bought $4.83M and sold $281,909 worth of stock each year.
Highest buying activity among insiders over the last 12 months: WINDSOR JAMES BRIAN (President and COO) — $21,491.
The last purchase of 225 shares for transaction amount of $758 was made by WINDSOR JAMES BRIAN (President and COO) on 2023‑12‑15.
2024-06-17 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 4,707 0.0219% | $3.25 | $15,298 | -4.05% | |
2024-06-14 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 1,900 0.009% | $3.30 | $6,270 | -3.73% | |
2024-06-12 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 9,342 0.0435% | $3.25 | $30,362 | -3.85% | |
2024-06-11 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 5,752 0.0269% | $3.26 | $18,744 | -3.10% | |
2024-06-10 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 9,577 0.046% | $3.30 | $31,604 | -0.31% | |
2024-06-07 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 1,740 0.0081% | $3.26 | $5,664 | -1.85% | |
2024-06-06 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 4,284 0.0199% | $3.29 | $14,104 | -2.89% | |
2024-06-05 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 6,291 0.0291% | $3.30 | $20,760 | -2.73% | |
2024-05-01 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 20,315 0.1211% | $4.21 | $85,473 | -20.19% | |
2024-04-30 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 90 0.0006% | $4.97 | $448 | -26.04% | |
2024-04-29 | Sale | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 10,746 0.0637% | $4.95 | $53,182 | -30.69% | |
2023-12-15 | WINDSOR JAMES BRIAN | President and COO | 225 0.0043% | $3.37 | $758 | +26.23% | ||
2023-11-20 | WINDSOR JAMES BRIAN | President and COO | 5,076 0.1087% | $1.97 | $9,987 | +118.70% | ||
2021-01-08 | Satter Muneer A | See Remarks | 9M 8.7946% | $1.10 | $9.9M | -14.81% | ||
2020-06-15 | Ambros Reinhard J. | director | 5,800 0.0189% | $1.22 | $7,076 | +2.50% | ||
2020-06-08 | Satter Muneer A | 3.7M 11.0475% | $1.10 | $4.07M | +4.24% | |||
2020-06-08 | VON RICKENBACH JOSEF H | director | 227,272 0.6786% | $1.10 | $249,999 | +4.24% | ||
2019-11-15 | Bailey Jeffrey Allen | director | 39,142 0.1624% | $0.51 | $19,962 | +60.68% | ||
2019-11-14 | Bailey Jeffrey Allen | director | 15,858 0.0646% | $0.51 | $8,088 | +57.84% | ||
2019-11-12 | Bailey Jeffrey Allen | director | 19,894 0.0805% | $0.53 | $10,544 | +50.37% |
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 10 percent owner | 1746549 10.5481% | $2.91 | 0 | 11 | |
WINDSOR JAMES BRIAN | President and COO | 225 0.0046% | $2.91 | 2 | 0 | |
Satter Muneer A | See Remarks | 16609449 339.9737% | $2.91 | 3 | 0 | <0.0001% |
Novartis Bioventures Ltd | 10 percent owner | 2079394 42.5625% | $2.91 | 1 | 27 | <0.0001% |
Gallagher Brian M. Jr. | director | 1431519 29.3013% | $2.91 | 1 | 0 | <0.0001% |
APPLE TREE PARTNERS II LP | 10 percent owner | 1380241 28.2517% | $2.91 | 0 | 15 | |
Shanafelt Armen | director | 1094987 22.413% | $2.91 | 1 | 0 | <0.0001% |
LV Management Group, LLC | 1094987 22.413% | $2.91 | 1 | 0 | <0.0001% | |
EXCEL MEDICAL FUND LP | 10 percent owner | 1016100 20.7982% | $2.91 | 1 | 0 | <0.0001% |
CVF, LLC | 10 percent owner | 716180 14.6593% | $2.91 | 1 | 0 | <0.0001% |
ROCHE HOLDING LTD | 10 percent owner | 702363 14.3765% | $2.91 | 1 | 0 | <0.0001% |
KCK LTD. | 10 percent owner | 646817 13.2395% | $2.91 | 1 | 0 | <0.0001% |
AJU IB Investment Co., Ltd. | 10 percent owner | 517558 10.5937% | $2.91 | 1 | 0 | <0.0001% |
VON RICKENBACH JOSEF H | director | 445460 9.118% | $2.91 | 7 | 0 | <0.0001% |
Sigma Emerging Markets Ltd. | 10 percent owner | 423086 8.66% | $2.91 | 1 | 0 | <0.0001% |
Vukovic Vojo | SVP, Chief Medical Officer | 75000 1.5352% | $2.91 | 1 | 0 | +13.56% |
Bailey Jeffrey Allen | director | 74894 1.533% | $2.91 | 3 | 0 | +56.3% |
Kapnick Scott | 66666 1.3646% | $2.91 | 1 | 0 | <0.0001% | |
Gregory Kathryn | SVP, Chief Business Officer | 45000 0.9211% | $2.91 | 1 | 0 | +7.54% |
LONGENECKER JOHN P PHD | President and CEO | 10000 0.2047% | $2.91 | 1 | 0 | <0.0001% |
Ambros Reinhard J. | director | 5800 0.1187% | $2.91 | 2 | 0 | <0.0001% |
Dougherty Donald | SVP & Chief Financial Officer | 5000 0.1023% | $2.91 | 2 | 0 | <0.0001% |
Aivado Manuel | See Remarks | 1000 0.0205% | $2.91 | 1 | 0 | <0.0001% |
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