Annovis Bio, Inc. (ANVS) Insider Trading Activity

NYSE$1.195+0.1 (9.17%)
Market Cap
$46.52M
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
95 of 849
Rank in Industry
58 of 491

ANVS Insider Trading Activity

ANVS Median Price and Trade Amounts History Chart

Statistics of Insider Transactions

Amount of Insider Buys and Sells

Buys
$2,213,587
7
100
Sells
$0
0
0

Related Transactions

Hoffman Michael Bdirector
7
$2.21M
0
$0
$2.21M

About Annovis Bio, Inc.

Annovis Bio, Inc. is a clinical-stage biopharmaceutical company focused on pioneering treatments for neurodegenerative disorders. The firm's flagship drug, Buntanetap, an oral medication, has successfully advanced through Phase 2a clinical trials for Alzheimer's and Parkinson's diseases. This compound is also currently being evaluated in clinical studies for Alzheimer's disease in individuals with Down Syndrome, as well as for various other chronic neurodegenerative conditions. Beyond Buntanetap, Annovis Bio is developing ANVS405 to offer …

Insider Activity of Annovis Bio, Inc.

Over the last 12 months, insiders at Annovis Bio, Inc. have bought $2.21M and sold $0 worth of Annovis Bio, Inc. stock.

On average, over the past 5 years, insiders at Annovis Bio, Inc. have bought $2.21M and sold $0 worth of stock each year.

Highest buying activity among insiders over the last 12 months: Hoffman Michael B (director) — $2.21M.

The last purchase of 76,344 shares for transaction amount of $142,779 was made by Hoffman Michael B (director) on 2026‑05‑20.

List of Insider Buy and Sell Transactions, Annovis Bio, Inc.

2026-05-20PurchaseHoffman Michael Bdirector
76,344
0.3558%
$1.87
$142,779
-15.69%
2026-04-02PurchaseHoffman Michael Bdirector
713,800
3.594%
$2.10
$1.5M
-23.03%
2025-12-08PurchaseHoffman Michael Bdirector
45,000
0.2279%
$4.31
$193,794
-56.05%
2025-11-24PurchaseHoffman Michael Bdirector
39,200
0.2144%
$4.08
$159,886
-53.06%
2025-11-24PurchaseHoffman Michael Bdirector
28,096
0.1564%
$4.15
$116,598
-53.06%
2025-11-21PurchaseHoffman Michael Bdirector
20,000
0.0937%
$3.50
$69,900
-49.34%
2025-11-14PurchaseHoffman Michael Bdirector
15,000
0.0703%
$2.11
$31,650
-17.73%
2025-10-28PurchaseHoffman Michael Bdirector
975,610
5.0805%
$2.05
$2M
-5.24%
2025-10-28PurchaseMaccecchini Maria-LuisaPresident & CEO
97,561
0.508%
$2.05
$200,000
-5.24%
2021-10-12PurchaseWhite Mark K.director
5,000
0.148%
$27.40
$137,000
-49.71%
2021-10-11PurchaseMaccecchini Maria-LuisaPRESIDENT AND CEO
18,000
0.5368%
$27.61
$496,980
-49.37%
2021-10-11PurchaseBruck Claudinedirector
181
0.0054%
$27.66
$5,006
-49.37%
2021-08-19PurchaseMcCarthy Reiddirector
500
0.0203%
$37.61
$18,805
-59.74%
2020-02-03PurchaseMcGroarty Jeffrey BrianChief Financial Officer
19,500
0.1506%
$7.15
$139,428
-30.90%
2020-01-31PurchaseMaccecchini Maria-LuisaPresident and CEO
1,600
0.0104%
$6.00
$9,600
-23.31%
2020-01-31PurchaseHoffman Michael B
33,333
0.216%
$6.00
$199,998
-23.31%
2020-01-31PurchaseMcGroarty Jeffrey BrianChief Financial Officer
33,333
0.216%
$6.00
$199,998
-23.31%
2020-01-31PurchaseWhelan, Jr. Robert M.director
25,000
0.162%
$6.00
$150,000
-23.31%
2020-01-31PurchaseWhite Mark K.director
1,734
0.0112%
$6.00
$10,404
-23.31%
2020-01-31PurchaseBruck Claudinedirector
800
0.0052%
$6.00
$4,800
-23.31%
Total: 20
*Gray background shows transactions not older than one year

Insider Historical Profitability

<0.0001%
Hoffman Michael Bdirector
3364883
7.8842%
$3.67M90
<0.0001%
Maccecchini Maria-LuisaPresident & CEO
1212020
2.8398%
$1.32M30
<0.0001%
White Mark K.director
56177
0.1316%
$61,232.9320
<0.0001%
McGroarty Jeffrey BrianChief Financial Officer
52833
0.1238%
$57,587.9720
Whelan, Jr. Robert M.director
25000
0.0586%
$27,250.0010
McCarthy Reiddirector
6829
0.016%
$7,443.6110
<0.0001%
Bruck Claudinedirector
6067
0.0142%
$6,613.0320
<0.0001%
*Gray background shows insiders who have made transactions during last year

Historical Insider Profitability vs. Competitors

$2,542,362
111
11.81%
$36.83M
$84,911,583
59
17.82%
$37.44M
$103,288,323
51
4.78%
$56.52M
$693,326
47
-16.24%
$40.24M
$24,478,755
37
-34.59%
$53.59M

ANVS Institutional Investors: Active Positions

Increased Positions38+111.76%3M+123.76%
Decreased Positions10-29.41%262,466-12.96%
New Positions20New2MNew
Sold Out Positions8Sold Out257,268Sold Out
Total Postitions62+82.35%4M+110.79%

ANVS Ownership Change vs Market

Institutional Investor Ownership

Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
Active Shareholders
Vanguard Group Inc$2,694.002.73%738,003+41,239+5.92%2025-09-30
Susquehanna International Group, Llp$797.000.81%218,421+53,863+32.73%2025-09-30
Geode Capital Management, Llc$672.000.68%184,154+867+0.47%2025-09-30
Citadel Advisors Llc$636.000.65%174,345+145,019+494.51%2025-09-30
Northern Trust Corp$442.000.45%121,060+61,546+103.41%2025-09-30
Merit Financial Group, Llc$297.000.3%81,316-10,000-10.95%2025-09-30
Blackrock, Inc.$294.000.3%80,67500%2025-09-30
Greenwich Wealth Management Llc$173.000.18%47,400+400+0.85%2025-09-30
Wescott Financial Advisory Group, Llc$152.000.15%41,60700%2025-09-30
State Street Corp$140.000.14%38,43500%2025-09-30

Financial Ratios

Summary
Comparison with Competitors

Price to Earnings

Price/Earnings to Growth

Price to Sales

Price to Book

Price/Free Cash Flow

Analyst Recommendations

Analyst Price Targets

Prismo does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.
Information is provided 'as-is' and solely for informational purposes and is not advice. Prismo does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.