Cabaletta Bio, Inc. (CABA) 

Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with B cell-mediated autoimmune diseases. Its proprietary technology utilizes chimeric autoantibody receptor (CAAR) T cells that are designed to selectively bind and eliminate B cells, which produce disease-causing autoantibodies or pathogenic B cells. The company's lead product candidate is DSG3-CAART, which is in Phase I clinical trial for the treatment of mucosal pemphigus vulgaris, an autoimmune blistering skin disease, and Hemophilia A with Factor VIII alloantibodies. Its product candidate pipeline also includes MuSK-CAART, a preclinical stage product to treat a subset of patients with myasthenia gravis; FVIII-CAART, a discovery stage product to treat a subset of patients with Hemophilia A; and DSG3/1-CAART, a discovery stage product for the treatment of mucocutaneous pemphigus vulgaris. It has a collaboration with the University of Pennsylvania; and research agreement with The Regents of the University of California. The company was formerly known as Tycho Therapeutics, Inc. and changed its name to Cabaletta Bio, Inc. in August 2018. Cabaletta Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.

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Over the last 12 months, insiders at Cabaletta Bio, Inc. have bought $0 and sold $1.29M worth of Cabaletta Bio, Inc. stock.

On average, over the past 5 years, insiders at Cabaletta Bio, Inc. have bought $6.52M and sold $5.25M worth of stock each year.

There was no buying activity among insiders over the last 12 months.

The last purchase of 8,127 shares for transaction amount of $10,152 was made by Nichtberger Steven (President & CEO) on 2022‑10‑19.