| $385M | ||
| $350M | ||
| $215M | ||
| $94M | ||
| $82M | ||
| $62M |
Buys | $0 | 0 | 0 |
Sells | $25,851 | 3 | 100 |
| Boyle Scott N | Chief Business Officer | 0 | $0 | 2 | $3,651 | $-3,651 |
| REYNO LEONARD | Chief Medical Officer | 0 | $0 | 1 | $22,200 | $-22,200 |
C4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins for the treatment of cancer, neurodegenerative conditions, and other diseases. Its lead product candidate is CFT7455, an orally bioavailable MonoDAC degrader of protein that is in Phase 1/2 trial targeting IKZF1 and IKZF3 for multiple myeloma and non-Hodgkin lymphomas, including peripheral T-cell lymphoma and mantle cell lymphoma. The company is also developing CFT8634, an orally bioavailable BiDAC degrader of BRD9, a protein target for synovial sarcoma and SMARCB1-deleted solid tumors; CFT1946, an orally bioavailable BiDAC degrader targeting V600X mutant BRAF to treat melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, and other solid malignancies; CFT8919, an orally bioavailable, allosteric, and mutant-selective BiDAC degrader of epidermal growth factor receptor, or EGFR, with an L858R mutation in NSCLC; and earlier stage programs comprising RET degraders for the treatment of various cancers. C4 Therapeutics, Inc. has strategic collaborations with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; Biogen MA, Inc.; and Calico Life Sciences LLC. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.
Over the last 12 months, insiders at C4 Therapeutics, Inc. have bought $0 and sold $25,851 worth of C4 Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at C4 Therapeutics, Inc. have bought $57,868 and sold $15.81M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 5,667 shares for transaction amount of $31,735 was made by Koppikar Utpal (director) on 2023‑02‑08.
| 2026-01-16 | Sale | REYNO LEONARD | Chief Medical Officer | 10,000 0.0139% | $2.22 | $22,200 | +0.90% | |
| 2025-02-18 | Sale | Boyle Scott N | Chief Business Officer | 669 0.0009% | $3.15 | $2,107 | -25.67% | |
| 2025-02-14 | Sale | Boyle Scott N | Chief Business Officer | 490 0.0007% | $3.15 | $1,544 | -30.50% | |
| 2023-02-08 | Koppikar Utpal | director | 5,667 0.0109% | $5.60 | $31,735 | -44.28% | ||
| 2022-04-12 | Hirsch Andrew | President & CEO | 10,000 0.0196% | $8.40 | $84,000 | -7.59% | ||
| 2022-01-04 | Sale | Crystal Adam | Chief Medical Officer | 30,000 0.0617% | $31.66 | $949,935 | -69.95% | |
| 2021-12-17 | Sale | Salter Malcolm | director | 1,510 0.0032% | $30.25 | $45,678 | -69.12% | |
| 2021-11-19 | Sale | Salter Malcolm | director | 1,510 0.0034% | $40.11 | $60,566 | -73.29% | |
| 2021-10-15 | Sale | Salter Malcolm | director | 1,510 0.0034% | $44.94 | $67,859 | -72.36% | |
| 2021-10-01 | Sale | Crystal Adam | Chief Medical Officer | 30,000 0.0644% | $45.43 | $1.36M | -54.31% | |
| 2021-09-27 | Sale | Prokupets Elena | director | 3,700 0.0076% | $50.04 | $185,146 | -56.99% | |
| 2021-09-24 | Sale | Prokupets Elena | director | 6,030 0.0127% | $50.10 | $302,130 | -56.18% | |
| 2021-09-23 | Sale | Prokupets Elena | director | 38,360 0.079% | $50.41 | $1.93M | -56.89% | |
| 2021-09-22 | Sale | Prokupets Elena | director | 21,096 0.0435% | $50.10 | $1.06M | -55.96% | |
| 2021-09-21 | Sale | Prokupets Elena | director | 20,642 0.0426% | $50.14 | $1.03M | -55.74% | |
| 2021-09-17 | Sale | Prokupets Elena | director | 21,680 0.0448% | $50.05 | $1.08M | -55.30% | |
| 2021-09-17 | Sale | Salter Malcolm | director | 1,510 0.0031% | $49.89 | $75,334 | -55.30% | |
| 2021-09-16 | Sale | Prokupets Elena | director | 52,998 0.1074% | $48.65 | $2.58M | -54.79% | |
| 2021-09-15 | Sale | Prokupets Elena | director | 108,386 0.2237% | $48.82 | $5.29M | -53.81% | |
| 2021-09-14 | Sale | Prokupets Elena | director | 1,968 0.0041% | $50.02 | $98,434 | -54.13% |
| REYNO LEONARD | Chief Medical Officer | 156382 0.2197% | $350,295.68 | 0 | 1 | |
| Boyle Scott N | Chief Business Officer | 107805 0.1515% | $241,483.20 | 0 | 2 | |
| Prokupets Elena | director | 31681 0.0445% | $70,965.44 | 0 | 14 | |
| Fisher Stewart | Chief Scientific Officer | 22744 0.032% | $50,946.56 | 0 | 3 | |
| Crystal Adam | Chief Medical Officer | 15000 0.0211% | $33,600.00 | 0 | 5 | |
| Salter Malcolm | director | 10952 0.0154% | $24,532.48 | 1 | 8 | +39.65% |
| Hirsch Andrew | President & CEO | 10000 0.014% | $22,400.00 | 1 | 0 | <0.0001% |
| Koppikar Utpal | director | 5667 0.008% | $12,694.08 | 1 | 0 | <0.0001% |
| MCKEE WILLIAM | Chief Financial Officer | 5263 0.0074% | $11,789.12 | 1 | 0 | +39.65% |
| COHEN MARC A | 5030 0.0071% | $11,267.20 | 1 | 0 | +39.65% | |
| Siegel Jolie | Chief Legal Officer | 0 0% | $0 | 0 | 2 |
$6,578,958 | 42 | 10.77% | $150.84M | |
$16,259,194 | 41 | 120.51% | $166.84M | |
$7,147,964 | 34 | 24.78% | $146.64M | |
$1,236,317 | 33 | 0.20% | $157.79M | |
$18,752,549 | 33 | -28.39% | $166.26M | |
$47,256,074 | 24 | -25.69% | $158.53M | |
$295,092,700 | 21 | -0.27% | $137.27M | |
$110,580 | 16 | 14.52% | $186.15M | |
$448,999,793 | 15 | -19.99% | $144.9M | |
$178,593,887 | 15 | -14.86% | $145.86M | |
$4,701,608 | 14 | -4.34% | $164.06M | |
$13,919,584 | 9 | -30.43% | $174.6M | |
$6,847,110 | 9 | 5.96% | $172.77M | |
$299,343 | 6 | -44.75% | $136.46M | |
C4 Therapeutics, Inc. (CCCC) | $556,839 | 5 | 13.42% | $159.44M |
$6,049,986 | 4 | -8.38% | $171.43M | |
$32,007,657 | 4 | -45.65% | $189.67M | |
$12,750 | 2 | -39.73% | $170.09M | |
$19,175,155 | 2 | 40.00% | $144.38M |
| Increased Positions | 47 | +33.57% | 6M | +10.51% |
| Decreased Positions | 64 | -45.71% | 8M | -14.51% |
| New Positions | 21 | New | 3M | New |
| Sold Out Positions | 26 | Sold Out | 1M | Sold Out |
| Total Postitions | 123 | -12.14% | 53M | -4% |
| Lynx1 Capital Management Lp | $13,699.00 | 7.32% | 7.1M | 0 | 0% | 2025-09-30 |
| Soleus Capital Management, L.P. | $13,614.00 | 7.27% | 7.05M | +75,000 | +1.07% | 2025-09-30 |
| Orbimed Advisors Llc | $10,104.00 | 5.4% | 5.24M | -2M | -23.35% | 2025-09-30 |
| Morgan Stanley | $9,596.00 | 5.13% | 4.97M | +217,844 | +4.58% | 2025-09-30 |
| Wasatch Advisors Lp | $9,366.00 | 5% | 4.85M | -3M | -34.64% | 2025-09-30 |
| Vanguard Group Inc | $6,160.00 | 3.29% | 3.19M | +173,535 | +5.75% | 2025-09-30 |
| Bank Of America Corp /De/ | $3,963.00 | 2.12% | 2.05M | +45,158 | +2.25% | 2025-09-30 |
| Millennium Management Llc | $3,733.00 | 1.99% | 1.93M | +832,883 | +75.62% | 2025-09-30 |
| Silverarc Capital Management, Llc | $3,662.00 | 1.96% | 1.9M | +2M | New | 2025-09-30 |
| Blackrock, Inc. | $3,080.00 | 1.65% | 1.6M | -232,975 | -12.74% | 2025-09-30 |