| $337M | ||
| $259M | ||
| $79M | ||
| $60M | ||
| $58M | ||
| $50M |
Buys | $12,958,699 | 36 | 100 |
Sells | $0 | 0 | 0 |
| Opaleye Management Inc. | 10 percent owner | 36 | $12.96M | 0 | $0 | $12.96M |
Codexis, Inc. discovers, develops, and sells enzymes and other proteins. It offers biocatalyst products and services; intermediate chemicals products that are used for further chemical processing; and Codex biocatalyst panels and kits that enable customers to perform chemistry screening. The company also provides biocatalyst screening and protein engineering services. In addition, it offers CodeEvolver protein engineering technology platform, which helps in developing and delivering biocatalysts that perform chemical transformations and enhance the efficiency and productivity of manufacturing processes. The company's platform is also used to discover novel biotherapeutic drug candidates for targeted human diseases, as well as for molecular biology and in vitro diagnostic enzymes. It sells its products to pharmaceutical manufacturers through its direct sales and business development force in the United States and Europe. The company was incorporated in 2002 and is headquartered in Redwood City, California.
Over the last 12 months, insiders at Codexis, Inc. have bought $12.96M and sold $0 worth of Codexis, Inc. stock.
On average, over the past 5 years, insiders at Codexis, Inc. have bought $6.56M and sold $3.89M worth of stock each year.
Highest buying activity among insiders over the last 12 months: Opaleye Management Inc. (10 percent owner) — $12.96M.
The last purchase of 50,898 shares for transaction amount of $114,012 was made by Opaleye Management Inc. (10 percent owner) on 2025‑06‑16.
| 2025-06-16 | Opaleye Management Inc. | 10 percent owner | 50,898 0.0614% | $2.24 | $114,012 | +2.23% | ||
| 2025-06-13 | Opaleye Management Inc. | 10 percent owner | 99,102 0.1196% | $2.23 | $220,997 | 0.00% | ||
| 2025-06-12 | Opaleye Management Inc. | 10 percent owner | 100,000 0.1207% | $2.25 | $225,000 | +0.44% | ||
| 2025-05-28 | Opaleye Management Inc. | 10 percent owner | 5,000 0.0061% | $2.36 | $11,800 | -2.89% | ||
| 2025-05-23 | Opaleye Management Inc. | 10 percent owner | 2.32M 2.7537% | $2.36 | $5.48M | -1.67% | ||
| 2025-05-01 | Opaleye Management Inc. | 10 percent owner | 20,000 0.0242% | $2.32 | $46,436 | +2.13% | ||
| 2025-04-30 | Opaleye Management Inc. | 10 percent owner | 25,000 0.0303% | $2.31 | $57,660 | +3.24% | ||
| 2025-04-25 | Opaleye Management Inc. | 10 percent owner | 25,000 0.0299% | $2.24 | $55,915 | +5.09% | ||
| 2025-04-17 | Opaleye Management Inc. | 10 percent owner | 45,000 0.0553% | $2.09 | $94,163 | +11.61% | ||
| 2025-04-16 | Opaleye Management Inc. | 10 percent owner | 70,000 0.0875% | $2.13 | $148,890 | +11.08% | ||
| 2025-04-15 | Opaleye Management Inc. | 10 percent owner | 25,000 0.0327% | $2.23 | $55,720 | +4.44% | ||
| 2025-04-08 | Opaleye Management Inc. | 10 percent owner | 100,000 0.1165% | $1.98 | $198,380 | +19.04% | ||
| 2025-04-03 | Opaleye Management Inc. | 10 percent owner | 75,000 0.0911% | $2.30 | $172,740 | +1.53% | ||
| 2025-04-02 | Opaleye Management Inc. | 10 percent owner | 5,000 0.006% | $2.46 | $12,276 | -7.03% | ||
| 2025-04-01 | Opaleye Management Inc. | 10 percent owner | 35,000 0.0417% | $2.48 | $86,772 | -7.37% | ||
| 2025-03-21 | Opaleye Management Inc. | 10 percent owner | 92,923 0.1118% | $2.54 | $236,266 | -7.84% | ||
| 2025-03-20 | Opaleye Management Inc. | 10 percent owner | 7.08 <0.0001% | $2.54 | $18 | -7.75% | ||
| 2025-03-13 | Opaleye Management Inc. | 10 percent owner | 85,000 0.1031% | $2.54 | $216,155 | -6.72% | ||
| 2025-03-06 | Opaleye Management Inc. | 10 percent owner | 100,000 0.1169% | $2.61 | $261,350 | -12.45% | ||
| 2025-03-05 | Opaleye Management Inc. | 10 percent owner | 10,000 0.0118% | $2.69 | $26,875 | -12.27% |
| Opaleye Management Inc. | 10 percent owner | 12250000 14.7867% | $28.79M | 36 | 0 | |
| NICOLS JOHN J | director | 783965 0.9463% | $1.84M | 4 | 31 | <0.0001% |
| DILLY STEPHEN GEORGE | See Remarks | 438878 0.5298% | $1.03M | 1 | 2 | +69.19% |
| KELLEY BERNARD J | director | 206136 0.2488% | $484,419.60 | 0 | 16 | |
| SHAW ALAN | President and CEO | 202000 0.2438% | $474,700.00 | 1 | 12 | +25.75% |
| Dorgan Byron L | director | 193461 0.2335% | $454,633.35 | 0 | 9 | |
| SANGSTER GORDON | SVP & Chief Financial Officer | 134453 0.1623% | $315,964.55 | 0 | 8 | |
| Lalonde James | SVP, R&D | 133402 0.161% | $313,494.70 | 0 | 14 | |
| Ryali Sriram | Chief Financial Officer | 123441 0.149% | $290,086.35 | 1 | 0 | +69.19% |
| O'Toole David D | SVP & Chief Financial Officer | 115384 0.1393% | $271,152.40 | 4 | 0 | <0.0001% |
| VIVO VENTURES VII, LLC | 10 percent owner | 112940 0.1363% | $265,409.00 | 0 | 5 | |
| Norrett Kevin | Chief Operating Officer | 98102 0.1184% | $230,539.70 | 1 | 2 | +65.06% |
| Vivo Ventures Fund VII, L.P. | 10 percent owner | 90330 0.109% | $212,275.50 | 0 | 1 | |
| Fitzgerald Margaret Nell | See Remarks | 81420 0.0983% | $191,337.00 | 1 | 2 | +69.19% |
| Anton David L. | SVP, BioIndustrials | 70200 0.0847% | $164,970.00 | 1 | 1 | +25.75% |
| Sheehy Douglas T. | SVP, General Counsel & Sec. | 69200 0.0835% | $162,620.00 | 1 | 1 | +25.75% |
| Glaub Kathleen Sereda | director | 63534 0.0767% | $149,304.90 | 0 | 3 | |
| Cheng Pam P. | director | 58719 0.0709% | $137,989.65 | 0 | 2 | |
| Smith David V | director | 56679 0.0684% | $133,195.65 | 0 | 1 | |
| Lawson Robert J | SVP and CFO | 44000 0.0531% | $103,400.00 | 2 | 0 | <0.0001% |
| Yang Patrick Y | 42512 0.0513% | $99,903.20 | 12 | 12 | +15.01% | |
| BARUCH THOMAS R | director | 33093 0.0399% | $77,768.55 | 1 | 15 | +28.81% |
| WOLF DENNIS P | 30925 0.0373% | $72,673.75 | 0 | 22 | ||
| Pasternack Bruce A | director | 10000 0.0121% | $23,500.00 | 3 | 0 | +29.98% |
| Sarret Joseph J. | CBO, President Pharmaceuticals | 2000 0.0024% | $4,700.00 | 1 | 0 | +25.75% |
| CMEA VENTURES LIFE SCIENCES 2000 LP | 0 0% | $0 | 0 | 1 | ||
| Aldridge Michael D. | See Remarks | 0 0% | $0 | 0 | 2 |
$22,608,361 | 93 | 3.94% | $208.23M | |
$54,762,250 | 63 | -1.52% | $208.97M | |
$87,639,490 | 62 | 18.37% | $189.87M | |
$613,304,943 | 46 | 11.85% | $186.26M | |
$17,983,739 | 41 | 102.87% | $200.91M | |
Codexis, Inc. (CDXS) | $2,545,071 | 34 | 16.59% | $194.69M |
$79,019,806 | 27 | 7.24% | $175.44M | |
$91,870,774 | 13 | 3.64% | $206.94M | |
$1,229,070 | 10 | 23.53% | $188.67M | |
$12,058,044 | 9 | 239.15% | $201.8M | |
$55,069,530 | 9 | 25.25% | $203.81M | |
$145,296,407 | 8 | -0.98% | $168.22M | |
$6,593,243 | 8 | 12.72% | $196.73M | |
$5,905,507 | 7 | 2.69% | $199.67M | |
$17,675,244 | 7 | 92.20% | $168.77M | |
$45,000,000 | 6 | -31.22% | $187.48M | |
$88,549,962 | 5 | -16.91% | $189.47M | |
$40,000,000 | 3 | -16.24% | $168.65M | |
$9,999,990 | 1 | 32.51% | $200.59M |
| Increased Positions | 68 | +47.89% | 8M | +12.82% |
| Decreased Positions | 60 | -42.25% | 4M | -6.68% |
| New Positions | 16 | New | 4M | New |
| Sold Out Positions | 22 | Sold Out | 2M | Sold Out |
| Total Postitions | 150 | +5.63% | 68M | +6.15% |
| Opaleye Management Inc. | $22,277.00 | 10.65% | 8.84M | +70,000 | +0.8% | 2024-12-31 |
| Casdin Capital, Llc | $20,412.00 | 9.76% | 8.1M | 0 | 0% | 2024-12-31 |
| Blackrock, Inc. | $19,114.00 | 9.14% | 7.58M | -57,820 | -0.76% | 2025-03-31 |
| Fmr Llc | $11,407.00 | 5.45% | 4.53M | +29,500 | +0.66% | 2024-12-31 |
| Vanguard Group Inc | $11,249.00 | 5.38% | 4.46M | +311,082 | +7.49% | 2024-12-31 |
| Telemark Asset Management, Llc | $7,560.00 | 3.61% | 3M | +303,589 | +11.26% | 2024-12-31 |
| Nantahala Capital Management, Llc | $7,161.00 | 3.42% | 2.84M | -126,148 | -4.25% | 2024-12-31 |
| Ameriprise Financial Inc | $6,047.00 | 2.89% | 2.4M | +12,625 | +0.53% | 2024-12-31 |
| Geode Capital Management, Llc | $4,676.00 | 2.24% | 1.86M | +211,475 | +12.86% | 2024-12-31 |
| Nuveen Asset Management, Llc | $4,567.00 | 2.18% | 1.81M | +283,760 | +18.56% | 2024-12-31 |