Chimerix, Inc. (CMRX)
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About Chimerix, Inc.
Chimerix, Inc., a biopharmaceutical company, develops medicines to enhance the lives of patients living with serious diseases. The company's approved product is TEMBEXA (brincidofovir), a lipid conjugate through inhibition of viral DNA synthesis that is developed as a medical countermeasure for smallpox. Its clinical stage development programs include ONC201 a program for treating tumors which harbor the H3 K27M mutation in recurrent diffuse midline glioma patients; ONC206, an imipridone, Dopamine Receptor D2 (DRD2) antagonist, and caseinolytic protease P (ClpP) agonist that demonstrated enhanced non-competitive DRD2 antagonism relative to ONC201, which is in Phase I clinical trials to treat solid tumors; ONC212, an imipridone agonist of the orphan G protein-coupled receptors (GPCR) tumor suppressor GPR132, as well as ClpP for solid tumors and hematological malignancies, including pancreatic cancer and leukemias; and dociparstat sodium (DSTAT), which inhibits the activities of key proteins implicated in the resistance of acute myeloid leukemia blasts and leukemic stem cells to chemotherapy. The company has license agreements with Biomedical Advanced Research and Development Authority for the development of brincidofovir for use in the treatment of smallpox; Cantex Pharmaceuticals, Inc. to develop and commercialize a glycosaminoglycan compound; and SymBio Pharmaceuticals to develop, manufacture, and commercialize BCV for various human indications. Chimerix, Inc. was incorporated in 2000 and is headquartered in Durham, North Carolina.
Insider Activity of Chimerix, Inc.
Over the last 12 months, insiders at Chimerix, Inc. have bought $38,647 and sold $10,192 worth of Chimerix, Inc. stock.
On average, over the past 5 years, insiders at Chimerix, Inc. have bought $191,562 and sold $7.53M worth of stock each year.
Highest buying activity among insiders over the last 12 months: MIDDLETON FRED A (director) — $115,940.
The last purchase of 17,295 shares for transaction amount of $16,522 was made by MIDDLETON FRED A (director) on 2023‑11‑17.
List of Insider Buy and Sell Transactions, Chimerix, Inc.
| 2024-02-14 | Sale | Andriole Michael T. | PRESIDENT AND CEO | 1,744 0.0019% | $1.04 | $1,809 | -6.86% | |
| 2024-02-14 | Sale | Jakeman David | VP OF FINANCE AND ACCOUNTING | 2,660 0.003% | $1.04 | $2,777 | -6.86% | |
| 2024-02-14 | Sale | LaSpaluto Michelle | CHIEF FINANCIAL OFFICER | 1,940 0.0022% | $1.04 | $2,023 | -6.86% | |
| 2023-11-17 | MIDDLETON FRED A | director | 17,295 0.0192% | $0.96 | $16,522 | +0.36% | ||
| 2023-11-10 | MIDDLETON FRED A | director | 2,705 0.003% | $0.92 | $2,489 | +2.30% | ||
| 2023-09-28 | Sale | Jakeman David | VP of Finance and Accounting | 3,610 0.0042% | $0.99 | $3,584 | -0.63% | |
| 2023-09-25 | MIDDLETON FRED A | director | 20,000 0.0226% | $0.98 | $19,636 | -1.43% | ||
| 2023-05-18 | Andriole Michael T. | Chief Business Officer and CFO | 51,700 0.0598% | $1.14 | $59,150 | -10.71% | ||
| 2023-05-12 | Sherman Michael A. | Chief Executive Officer | 87,000 0.0987% | $1.12 | $97,652 | -9.82% | ||
| 2023-05-10 | DEMSKI MARTHA J | director | 18,000 0.02% | $1.11 | $19,980 | -10.62% | ||
| 2023-05-08 | Meyer Robert J. | director | 8,750 0.0101% | $1.14 | $9,975 | -9.82% | ||
| 2023-03-28 | MIDDLETON FRED A | director | 20,000 0.023% | $1.21 | $24,152 | -10.92% | ||
| 2023-01-26 | Sale | Jakeman David | Principal Accounting Officer | 3,230 0.0036% | $1.76 | $5,686 | -36.80% | |
| 2022-09-29 | Sale | Jakeman David | Principal Accounting Officer | 4,400 0.005% | $1.86 | $8,185 | -24.86% | |
| 2022-09-29 | MIDDLETON FRED A | 20,000 0.0229% | $1.86 | $37,176 | -24.86% | |||
| 2022-05-19 | Meyer Robert J. | 1,419 0.0015% | $2.05 | $2,909 | -16.36% | |||
| 2022-05-19 | MIDDLETON FRED A | 20,000 0.0212% | $2.04 | $40,738 | -16.36% | |||
| 2022-05-17 | Andriole Michael T. | Chief Business Officer and CFO | 15,000 0.0168% | $1.71 | $25,635 | +5.14% | ||
| 2022-05-17 | DEMSKI MARTHA J | 10,000 0.0105% | $1.61 | $16,100 | +5.14% | |||
| 2022-02-04 | Sale | Jakeman David | Principal Accounting Officer | 3,300 0.0038% | $5.56 | $18,355 | -60.79% |
Insider Historical Profitability
| Andriole Michael T. | Chief Business Officer and CFO | 447021 0.4016% | $0.88 | 4 | 1 | +44.13% |
| Jakeman David | VP of Finance and Accounting | 141232 0.1498% | $0.88 | 0 | 10 | |
| LaSpaluto Michelle | CHIEF FINANCIAL OFFICER | 110999 0.1249% | $0.88 | 0 | 1 | |
| MIDDLETON FRED A | director | 100000 0.1125% | $0.88 | 12 | 0 | +17.74% |
| CANTEX PHARMACEUTICALS, INC. | 10 percent owner | 3500000 3.9374% | $0.88 | 0 | 1 | |
| Canaan VII L P | 2584990 2.908% | $0.88 | 0 | 1 | ||
| Hutton Wende S | 2584990 2.908% | $0.88 | 0 | 1 | ||
| New Leaf Ventures II, L.P. | director | 2243394 2.5237% | $0.88 | 0 | 1 | |
| CHAMPSI FARAH | director | 1714330 1.9286% | $0.88 | 0 | 1 | |
| NIEDEL JAMES | director | 1046082 1.1768% | $0.88 | 0 | 4 | |
| Sanderling Venture Partners V, LP | 10 percent owner | 993646 1.1178% | $0.88 | 0 | 1 | |
| PAPPAS ARTHUR M | director | 830695 0.9345% | $0.88 | 0 | 1 | |
| Sanderling Venture Partners VI Co Investment Fund LP | 10 percent owner | 697346 0.7845% | $0.88 | 0 | 2 | |
| Nichols Garrett | Chief Medical Officer | 260066 0.2926% | $0.88 | 0 | 3 | |
| MARIO ERNEST | director | 108167 0.1217% | $0.88 | 19 | 9 | +22.4% |
| Berrey M Michelle | President and CEO | 99685 0.1121% | $0.88 | 5 | 0 | +24.59% |
| Sherman Michael A. | Chief Executive Officer | 87000 0.0979% | $0.88 | 3 | 0 | +23.84% |
| DEMSKI MARTHA J | director | 72055 0.0811% | $0.88 | 4 | 16 | <0.0001% |
| Richardson Linda M | Chief Commercial Officer | 60996 0.0686% | $0.88 | 0 | 1 | |
| Meyer Robert J. | director | 35150 0.0395% | $0.88 | 5 | 0 | +34.82% |
| WOLLAEGER TIMOTHY | director | 10000 0.0112% | $0.88 | 1 | 3 | <0.0001% |
| Machado Clarence Patrick | director | 10000 0.0112% | $0.88 | 1 | 0 | <0.0001% |
| Trost Timothy W. | SVP, CFO & Secretary | 9850 0.0111% | $0.88 | 0 | 14 | |
| DRAKE RODMAN L | director | 3500 0.0039% | $0.88 | 5 | 0 | +42.2% |
| Ricciardi Lisa | director | 1950 0.0022% | $0.88 | 1 | 0 | |
| MOCH KENNETH I | President and CEO | 1313 0.0015% | $0.88 | 0 | 4 | |
| LEONARD JOHN M. | director | 0 0% | $0.88 | 2 | 1 | +38.28% |
Institutional Investor Ownership
| RA Capital Management, L.P. | $9.33M | 9.82 | 8.8M | 0% | +$0 | 0.01 | |
| Monaco Asset Management Sam | $4.64M | 4.88 | 4.38M | 0% | +$0 | 2.13 | |
| The Vanguard Group | $4.61M | 4.85 | 4.35M | 0% | +$0 | <0.0001 | |
| Armistice Capital Llc | $2.4M | 2.53 | 2.26M | -12.86% | -$354,040.00 | 0.03 | |
| Acadian Asset Management | $2.3M | 2.43 | 2.17M | +15.51% | +$309,325.09 | 0.01 | |
| Citadel Advisors LLC | $2.01M | 2.11 | 1.9M | -8.11% | -$177,404.76 | <0.01 | |
| Renaissance Technologies | $1.97M | 2.07 | 1.85M | +18.68% | +$309,307.45 | <0.01 | |
| Goldman Sachs | $1.23M | 1.29 | 1.16M | -1.7% | -$21,255.12 | <0.0001 | |
| Millennium Management LLC | $1.16M | 1.22 | 1.09M | +0.31% | +$3,531.92 | <0.01 | |
| Bridgeway Capital Management | $1.15M | 1.21 | 1.08M | +4.81% | +$52,575.98 | 0.02 | |
| BlackRock | $1.08M | 1.13 | 1.01M | -3.06% | -$33,885.02 | <0.0001 | |
| Geode Capital Management | $1.03M | 1.09 | 972,799 | +6.58% | +$63,655.11 | <0.0001 | |
| Acuitas Investments, LLC | $673,377.00 | 0.71 | 635,261 | +100.66% | +$337,800.97 | 0.35 | |
| Northern Trust | $591,995.00 | 0.62 | 558,486 | -19.1% | -$139,740.82 | <0.0001 | |
| Yakira Capital Management Inc | $538,892.00 | 0.57 | 508,389 | 0% | +$0 | 0.03 | |
| Assenagon Asset Management S.A. | $481,736.00 | 0.51 | 454,468 | -9% | -$47,618.37 | <0.01 | |
| Tejara Capital Ltd | $439,296.00 | 0.46 | 414,430 | -24.66% | -$143,784.83 | 0.15 | |
| Adage Capital Partners Gp L L C | $424,000.00 | 0.45 | 400,000 | 0% | +$0 | <0.01 | |
| BNY Mellon | $411,831.00 | 0.43 | 388,520 | -8.69% | -$39,201.96 | <0.0001 | |
| D. E. Shaw & Co. | $397,104.00 | 0.42 | 374,626 | +37.95% | +$109,240.54 | <0.01 | |
| Barclays | $347,000.00 | 0.37 | 327,356 | -63.29% | -$598,219.79 | <0.0001 | |
| State Street | $312,467.00 | 0.33 | 294,780 | -2.71% | -$8,692.01 | <0.0001 | |
| Shay Capital Llc | $253,220.00 | 0.27 | 238,887 | +0.36% | +$915.84 | 0.08 | |
| Connor Clark & Lunn Investment Management Ltd | $209,930.00 | 0.22 | 198,047 | -9.39% | -$21,759.70 | <0.0001 | |
| Tealwood Asset Management | $122,970.00 | 0.13 | 116,009 | +24.34% | +$24,071.63 | 0.03 | |
| Pale Fire Capital Se | $111,084.00 | 0.12 | 104,796 | -50.38% | -$112,803.32 | <0.01 | |
| Credit Suisse | $99,640.00 | 0.11 | 94,000 | -29.85% | -$42,400.00 | <0.0001 | |
| Verition Fund Management Llc | $84,800.00 | 0.09 | 80,000 | 0% | +$0 | <0.01 | |
| Ci Private Wealth Llc | $76,379.00 | 0.08 | 72,055 | 0% | +$0 | <0.0001 | |
| Vontobel Holding Ltd | $74,200.00 | 0.08 | 70,000 | 0% | +$0 | <0.01 | |
| Morgan Stanley | $72,292.00 | 0.08 | 68,199 | -82.22% | -$334,397.80 | <0.0001 | |
| Royal Bank of Canada | $56,000.00 | 0.06 | 52,400 | -37.81% | -$34,049.92 | <0.0001 | |
| Two Sigma | $52,058.00 | 0.06 | 49,111 | +334.61% | +$40,079.92 | <0.0001 | |
| Vance Wealth Inc | $50,159.00 | 0.05 | 47,320 | 0% | +$0 | 0.03 | |
| Susquehanna International Group | $49,470.00 | 0.05 | 46,670 | +35.43% | +$12,941.49 | <0.0001 | |
| Raymond James Associates | $45,792.00 | 0.05 | 43,200 | 0% | +$0 | <0.0001 | |
| Prelude Capital | $43,884.00 | 0.05 | 41,400 | New | +$43,884.00 | <0.01 | |
| Koshinski Asset Management Inc | $107,200.00 | 0.05 | 40,000 | New | +$107,200.00 | 0.01 | |
| Point72 Asia Singapore Pte Ltd | $39,121.00 | 0.04 | 36,907 | New | +$39,121.00 | <0.01 | |
| Xtx Topco Ltd | $38,061.00 | 0.04 | 35,907 | -56.7% | -$49,840.65 | <0.01 | |
| StoneRidge Investment Partners LLC | $38,000.00 | 0.04 | 36,171 | New | +$38,000.00 | 0.01 | |
| Joel Isaacson & Co., LLC | $35,662.00 | 0.04 | 33,643 | 0% | +$0 | <0.01 | |
| Russell Investments Group Ltd | $34,556.00 | 0.04 | 32,600 | 0% | +$0 | <0.0001 | |
| Fidelity Investments | $31,229.00 | 0.03 | 29,461 | -40.65% | -$21,384.67 | <0.0001 | |
| UBS | $29,935.00 | 0.03 | 28,241 | -36.33% | -$17,081.64 | <0.0001 | |
| Two Sigma Advisers LP | $28,620.00 | 0.03 | 27,000 | +21.08% | +$4,982.00 | <0.0001 | |
| Toroso Investments Llc | $24,249.00 | 0.03 | 22,876 | New | +$24,249.00 | <0.0001 | |
| Simplex Trading Llc | $22,000.00 | 0.02 | 21,638 | +90.16% | +$10,430.63 | <0.01 | |
| Wells Fargo | $20,547.00 | 0.02 | 19,384 | +2,900.62% | +$19,862.24 | <0.0001 | |
| Jane Street Capital | $18,864.00 | 0.02 | 17,796 | -90.89% | -$188,160.87 | <0.0001 |