Crinetics Pharmaceuticals, Inc., a clinical stage pharmaceutical company, focuses on the discovery, development, and commercialization of therapeutics for rare endocrine diseases and endocrine-related tumors. Its lead product candidate is Paltusotine, an oral selective nonpeptide somatostatin receptor type 2 agonist that has completed phase III clinical trial for the treatment of acromegaly, as well as completed phase II clinical trial to treat carcinoid syndrome and nonfunctional neuroendocrine tumors (NETs). The company is also developing CRN04777, an oral selective nonpeptide somatostatin type 5 receptor agonist, which is in phase I clinical trial for the treatment of congenital hyperinsulinism; and CRN04894, an oral adrenocorticotrophic hormone antagonist that is in phase I clinical trial for the treatment of Cushing's and congenital adrenal hyperplasia diseases. Crinetics Pharmaceuticals, Inc. was incorporated in 2008 and is headquartered in San Diego, California.
Over the last 12 months, insiders at Crinetics Pharmaceuticals, Inc. have bought $0 and sold $24.27M worth of Crinetics Pharmaceuticals, Inc. stock.
On average, over the past 5 years, insiders at Crinetics Pharmaceuticals, Inc. have bought $11.86M and sold $9.06M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 5,000 shares for transaction amount of $110,300 was made by Vivaldi Coelho Rogerio (director) on 2023‑06‑08.
2024-06-25 | Sale | Betz Stephen F. | Chief Scientific Officer | 3,000 0.0038% | $45.37 | $136,110 | -7.01% | |
2024-06-24 | Sale | Pizzuti Dana | Chief Med and Dev Officer | 9,500 0.0121% | $45.73 | $434,435 | -1.73% | |
2024-06-21 | Sale | Hassard James | Chief Commercial Officer | 15,000 0.019% | $44.66 | $669,900 | -0.69% | |
2024-06-10 | Sale | Betz Stephen F. | Chief Scientific Officer | 3,000 0.0037% | $43.86 | $131,580 | +0.20% | |
2024-05-28 | Sale | Betz Stephen F. | Chief Scientific Officer | 3,000 0.0039% | $47.49 | $142,470 | -3.20% | |
2024-05-10 | Sale | Betz Stephen F. | Chief Scientific Officer | 3,000 0.0039% | $49.43 | $148,290 | -2.91% | |
2024-05-08 | Sale | Struthers Richard Scott | President & CEO | 107,448 0.1325% | $49.40 | $5.31M | -7.86% | |
2024-04-15 | Sale | Pizzuti Dana | Chief Med and Dev Officer | 14,375 0.0188% | $44.47 | $639,256 | +4.88% | |
2024-04-04 | Sale | Struthers Richard Scott | President & CEO | 40,951 0.0554% | $49.17 | $2.01M | -1.67% | |
2024-03-28 | Sale | Okey Stephanie | director | 17,500 0.0222% | $46.38 | $811,650 | -1.28% | |
2024-03-22 | Sale | Knight Jeff E. | Chief Operating Officer | 32,359 0.0415% | $44.31 | $1.43M | +3.82% | |
2024-03-20 | Sale | Pizzuti Dana | Chief Med and Dev Officer | 15,089 0.0188% | $44.06 | $664,763 | +0.79% | |
2024-03-20 | Sale | Fust Matthew K | director | 47,500 0.0593% | $44.28 | $2.1M | +0.79% | |
2024-03-19 | Sale | Wilson Marc | CFO | 6,942 0.0085% | $42.91 | $297,881 | +1.46% | |
2024-01-25 | Sale | Betz Stephen F. | Chief Scientific Officer | 3,000 0.0045% | $37.26 | $111,780 | +19.43% | |
2024-01-10 | Sale | Betz Stephen F. | Chief Scientific Officer | 3,000 0.0045% | $37.65 | $112,950 | +16.96% | |
2024-01-03 | Sale | Pizzuti Dana | Chief Med and Dev Officer | 14,375 0.0216% | $35.00 | $503,125 | +24.98% | |
2024-01-02 | Sale | Wilson Marc | CFO | 10,000 0.015% | $35.47 | $354,700 | +23.56% | |
2023-12-26 | Sale | Betz Stephen F. | Chief Scientific Officer | 3,000 0.0044% | $35.89 | $107,670 | +19.45% | |
2023-12-21 | Sale | Pizzuti Dana | Chief Med and Dev Officer | 9,583 0.0143% | $34.57 | $331,284 | +24.43% |
Struthers Richard Scott | President & CEO | 257485 0.2029% | $42.19 | 2 | 13 | +35.75% |
Wilson Marc | CFO | 110630 0.1438% | $42.19 | 0 | 4 | |
Betz Stephen F. | Chief Scientific Officer | 80643 0.1097% | $42.19 | 0 | 42 | |
Krasner Alan Seth | Chief Medical Officer | 43210 0.0647% | $42.19 | 1 | 2 | +10.46% |
Hassard James | Chief Commercial Officer | 29259 0.0371% | $42.19 | 0 | 1 | |
Fust Matthew K | 18536 0.0188% | $42.19 | 0 | 8 | ||
Pizzuti Dana | Chief Med and Dev Officer | 27786 0.0088% | $42.19 | 0 | 6 | |
Okey Stephanie | director | 6000 0.0077% | $42.19 | 0 | 1 | |
Knight Jeff E. | Chief Operating Officer | 52580 0.0074% | $42.19 | 0 | 2 | |
EDELMAN JOSEPH | 5321032 7.9657% | $42.19 | 1 | 0 | <0.0001% | |
PERCEPTIVE ADVISORS LLC | 10 percent owner | 5163517 7.7299% | $42.19 | 5 | 0 | +3.73% |
Vivo Capital VIII, LLC | 10 percent owner | 298625 0.447% | $42.19 | 1 | 13 | +10.46% |
Madan Ajay | Chief Development Officer | 176995 0.265% | $42.19 | 0 | 2 | |
5AM Ventures IV, L.P. | 94489 0.1415% | $42.19 | 1 | 3 | +10.46% | |
Vivaldi Coelho Rogerio | director | 5000 0.0075% | $42.19 | 1 | 0 | +52.25% |
BlackRock | $254.46M | 6.89 | 5.44M | +1.7% | +$4.26M | 0.01 | |
Driehaus Capital Management LLC | $244.64M | 6.63 | 5.23M | +3.7% | +$8.72M | 2.45 | |
Point72 Asset Management | $231.69M | 6.28 | 4.95M | +44.85% | +$71.74M | 0.44 | |
Fidelity Investments | $208.94M | 5.66 | 4.46M | +10.38% | +$19.65M | 0.01 | |
Ecor1 Capital Llc | $194.51M | 5.27 | 4.16M | +106.48% | +$100.31M | 4.95 | |
T. Rowe Price | $178.97M | 4.85 | 3.82M | +27.07% | +$38.12M | 0.02 | |
The Vanguard Group | $167.35M | 4.53 | 3.58M | +2.07% | +$3.4M | <0.01 | |
State Street | $152.38M | 4.13 | 3.26M | -8.66% | -$14.44M | 0.01 | |
Paradigm BioCapital Advisors LP | $146.27M | 3.96 | 3.12M | +35.1% | +$38M | 5.31 | |
Wellington Management Company | $139.1M | 3.77 | 2.97M | -8.43% | -$12.8M | 0.02 | |
JENNISON ASSOCIATES LLC | $131.9M | 3.57 | 2.82M | +10.61% | +$12.65M | 0.09 | |
T Rowe Price Investment Management Inc | $124.27M | 3.37 | 2.65M | +9.81% | +$11.11M | 0.08 | |
Janus Henderson | $92.53M | 2.51 | 1.98M | +264.13% | +$67.12M | 0.05 | |
First Light Asset Management | $79.12M | 2.14 | 1.69M | -14.97% | -$13.93M | 6.25 | |
Perceptive Advisors | $69.1M | 1.87 | 1.48M | +17.58% | +$10.33M | 0.05 | |
Geode Capital Management | $65.61M | 1.78 | 1.4M | +3.6% | +$2.28M | 0.01 | |
Artal Group S A | $65.09M | 1.76 | 1.39M | New | +$65.09M | 0.35 | |
OrbiMed | $64.83M | 1.76 | 1.39M | -16.93% | -$13.22M | 1.32 | |
Cormorant Asset Management Lp | $53.83M | 1.46 | 1.15M | 0% | +$0 | 2.55 | |
Novo Holdings A/S | $51.43M | 1.39 | 1.1M | -0.13% | -$65,534.00 | 3.59 | |
Eventide Asset Management | $49.6M | 1.34 | 1.06M | 0% | +$0 | 0.78 | |
Lord Abbett | $45.15M | 1.22 | 964,568 | +24.09% | +$8.77M | 0.16 | |
Goldman Sachs | $40.45M | 1.1 | 864,107 | +32.9% | +$10.01M | 0.01 | |
Saturn V Capital Management Llc | $30.9M | 0.84 | 660,143 | -16.13% | -$5.94M | 12.39 | |
Ikarian Capital LLC | $30.13M | 0.82 | 643,751 | -5.38% | -$1.71M | 8.6 | |
Dimensional Fund Advisors | $30M | 0.81 | 640,802 | -2.9% | -$894,960.40 | 0.01 | |
Adage Capital Partners Gp L L C | $29.59M | 0.8 | 632,133 | New | +$29.59M | 0.05 | |
Laurion Capital Management LP | $29.5M | 0.8 | 630,182 | +10.76% | +$2.86M | 0.82 | |
Ensign Peak Advisors Inc | $29.09M | 0.79 | 621,507 | +42.65% | +$8.7M | 0.05 | |
Morgan Stanley | $28.66M | 0.78 | 612,200 | -5.56% | -$1.69M | <0.01 | |
Northern Trust | $28.15M | 0.76 | 601,384 | -0.17% | -$48,588.78 | 0.01 | |
Nuveen | $25.91M | 0.7 | 553,739 | -18.47% | -$5.87M | 0.01 | |
Bioimpact Capital Llc | $22.5M | 0.61 | 480,588 | +0.49% | +$110,190.74 | 3.64 | |
Charles Schwab | $22.4M | 0.61 | 478,532 | +1.74% | +$381,922.79 | 0.01 | |
Fiera Capital | $22.26M | 0.6 | 475,510 | New | +$22.26M | 0.07 | |
Affinity Asset Advisors | $22M | 0.6 | 470,000 | +5.12% | +$1.07M | 3.91 | |
Fisher Asset Management Llc | $20.41M | 0.55 | 436,023 | -1.2% | -$246,782.30 | 0.01 | |
Franklin Templeton Investments | $19.34M | 0.52 | 413,209 | 0% | +$0 | 0.01 | |
GW&K Investment Management | $18.16M | 0.49 | 388,066 | -19% | -$4.26M | 0.16 | |
JPMorgan Chase | $17.6M | 0.48 | 375,986 | +303.83% | +$13.24M | <0.01 | |
Bank of America | $16.72M | 0.45 | 357,142 | +3.7% | +$595,844.49 | <0.01 | |
Vivo Capital | $16.38M | 0.44 | 350,000 | 0% | +$0 | 1.44 | |
Integral Health Asset Management Llc | $15.21M | 0.41 | 325,000 | +62.5% | +$5.85M | 1.51 | |
Duquesne Family Office Llc | $14.46M | 0.39 | 309,000 | New | +$14.46M | 0.39 | |
BNY Mellon | $13.88M | 0.38 | 296,478 | -10.04% | -$1.55M | <0.01 | |
ROCK SPRINGS CAPITAL MANAGEMENT, LP | $13.55M | 0.37 | 289,400 | New | +$13.55M | 0.35 | |
Millennium Management LLC | $12.41M | 0.34 | 265,011 | -29.07% | -$5.08M | 0.01 | |
Victory Capital Management Inc | $12.04M | 0.33 | 257,145 | +39.67% | +$3.42M | 0.01 | |
Citigroup | $11.61M | 0.32 | 248,050 | +142.45% | +$6.82M | 0.01 | |
UBS | $11.6M | 0.31 | 247,803 | +78.96% | +$5.12M | <0.01 |