Cyclerion Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovering, development, and commercialization of medicines for serious central nervous system (CNS) diseases. Its lead product candidate is CY6463, a CNS-penetrant, soluble guanylate cyclase (sGC) stimulator that is in Phase IIa trials for the treatment of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes, as well as Alzheimer's disease with vascular pathology; and Phase 1 trials diagnosed with schizophrenia in adults. It is also developing Praliciguat, an orally administered systemic sGC stimulator, which is in Phase II studies to treat resistant hypertension and diabetic nephropathy; Olinciguat, an orally administered vascular sGC stimulator that is in Phase II studies for the sickle cell disease; and CY3018 for the treatment of disorders of the CNS. It has license agreement with Akebia Therapeutics, Inc. for the development, manufacture, medical affairs, and commercialization of pharmaceutical products, including pharmaceutical compound, and other related products and forms. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.
Over the last 12 months, insiders at Cyclerion Therapeutics, Inc. have bought $0 and sold $27 worth of Cyclerion Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Cyclerion Therapeutics, Inc. have bought $4.49M and sold $80,008 worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 961,538 shares for transaction amount of $3M was made by Slate Path Capital LP (10 percent owner) on 2021‑06‑03.
2023-08-09 | Sale | MCGUIRE TERRANCE | director | 8 0.0003% | $3.40 | $27 | -10.12% | |
2021-06-03 | Slate Path Capital LP | 10 percent owner | 961,538 0.1301% | $3.12 | $3M | -39.01% | ||
2021-06-03 | Hecht Peter M | Chief Executive Officer | 823,170 0.1171% | $3.28 | $2.7M | -39.01% | ||
2021-06-03 | MCGUIRE TERRANCE | director | 96,153 0.013% | $3.12 | $299,997 | -39.01% | ||
2021-05-06 | Hecht Peter M | Chief Executive Officer | 302,000 0.0413% | $2.43 | $733,860 | +6.43% | ||
2021-05-05 | Hecht Peter M | Chief Executive Officer | 398,001 0.0553% | $2.53 | $1.01M | +3.92% | ||
2021-05-04 | Hecht Peter M | Chief Executive Officer | 300,000 0.0415% | $2.29 | $687,000 | +14.22% | ||
2021-02-25 | Sale | Wright Christopher I | Chief Medical Officer | 2,637 0.0004% | $3.99 | $10,522 | -24.61% | |
2021-02-25 | Sale | Gjino Anjeza | Chief Financial Officer | 1,824 0.0003% | $4.00 | $7,296 | -24.61% | |
2020-12-28 | Sale | Currie Mark G | President and CSO | 20,107 0.0032% | $3.01 | $60,522 | +3.68% | |
2020-11-09 | Busch Andreas | Chief Innovation Officer | 125,000 0.0199% | $2.53 | $316,250 | +27.42% | ||
2020-11-06 | Sale | Huyett William | Chief Financial Officer | 3,827 0.0006% | $2.52 | $9,644 | +27.42% | |
2020-02-21 | Sale | Huyett William | Chief Financial Officer | 3,559 0.0007% | $5.12 | $18,222 | -16.49% | |
2019-12-30 | Sale | Currie Mark G | President | 25,000 0.0839% | $2.48 | $62,000 | +42.59% | |
2019-12-27 | Sale | Currie Mark G | President | 25,000 0.0917% | $2.55 | $63,750 | +51.97% | |
2019-11-15 | Busch Andreas | Chief Innovation Officer | 125,000 0.4616% | $1.82 | $227,500 | +114.44% | ||
2019-11-08 | Sale | Huyett William | Chief Financial Officer | 3,922 0.0155% | $2.05 | $8,040 | +103.16% | |
2019-04-08 | SCHULMAN AMY W | director | 626,117 0.1105% | $16.00 | $10.02M | -46.83% | ||
2019-04-08 | MCGUIRE TERRANCE | director | 626,117 0.1105% | $16.00 | $10.02M | -46.83% | ||
2019-04-02 | Currie Mark G | President | 270,107 0.0504% | $14.81 | $4M | -38.92% |
MCGUIRE TERRANCE | director | 0 0% | $2.48 | 2 | 1 | <0.0001% |
Slate Path Capital LP | 10 percent owner | 7157601 292.7324% | $2.48 | 1 | 0 | <0.0001% |
Hecht Peter M | Chief Executive Officer | 2047698 83.747% | $2.48 | 4 | 0 | <0.0001% |
SCHULMAN AMY W | director | 604482 24.7222% | $2.48 | 1 | 0 | |
Busch Andreas | Chief Innovation Officer | 254704 10.4169% | $2.48 | 2 | 0 | +70.93% |
Currie Mark G | President and CSO | 251648 10.2919% | $2.48 | 1 | 3 | |
Huyett William | Chief Financial Officer | 67590 2.7643% | $2.48 | 0 | 3 | |
Wright Christopher I | Chief Medical Officer | 42728 1.7475% | $2.48 | 0 | 1 | |
Gjino Anjeza | Chief Financial Officer | 31599 1.2923% | $2.48 | 0 | 1 |
Slate Path Capital LP | $1.15M | 13.21 | 357,880 | 0% | +$0 | 0.02 | |
Mfn Partners Management Lp | $542,272.00 | 6.25 | 169,460 | 0% | +$0 | 0.02 | |
Tyndall Capital Partners L P | $527,286.00 | 6.08 | 164,777 | +0.21% | +$1,113.60 | 100 | |
Fidelity Investments | $519,447.00 | 5.99 | 162,327 | -0.32% | -$1,670.40 | <0.0001 | |
Artal Group S A | $444,656.00 | 5.13 | 138,955 | 0% | +$0 | <0.01 | |
Geode Capital Management | $102,694.00 | 1.18 | 32,082 | +2.63% | +$2,634.41 | <0.0001 | |
The Vanguard Group | $75,168.00 | 0.87 | 23,490 | 0% | +$0 | <0.0001 | |
BlackRock | $54,941.00 | 0.63 | 17,169 | 0% | +$0 | <0.0001 | |
UBS | $8,077.00 | 0.09 | 2,524 | +13.29% | +$947.22 | <0.0001 | |
Morgan Stanley | $2,077.00 | 0.02 | 649 | -7.02% | -$156.81 | <0.0001 | |
Group One Trading | $1,728.00 | 0.02 | 540 | 0% | +$0 | <0.0001 | |
Royal Bank of Canada | $1,000.00 | 0.01 | 352 | +6.67% | +$62.50 | <0.0001 | |
Wells Fargo | $48.00 | <0.01 | 15 | 0% | +$0 | <0.0001 | |
Tower Research Capital | $106.00 | <0.01 | 33 | New | +$106.00 | <0.0001 | |
Northwestern Mutual Wealth Management Co | $3.00 | <0.01 | 1 | 0% | +$0 | <0.0001 |