| $385M | ||
| $350M | ||
| $215M | ||
| $82M | ||
| $76M | ||
| $62M |
Buys | $0 | 0 | 0 |
Sells | $27,230,201 | 71 | 100 |
| Bhanji Muna | director | 0 | $0 | 1 | $43,227 | $-43,227 |
| Harrington Robert Arthur | director | 0 | $0 | 3 | $266,004 | $-266,004 |
| PARSHALL B LYNNE | director | 0 | $0 | 2 | $629,700 | $-629,700 |
| HENDERSON JOHN T | director | 0 | $0 | 2 | $682,450 | $-682,450 |
| WIERENGA WENDALL | director | 0 | $0 | 1 | $769,200 | $-769,200 |
| WIERENGA WENDELL | director | 0 | $0 | 1 | $1.32M | $-1.32M |
| Malik Fady Ibraham | EVP Research & Development | 0 | $0 | 21 | $2.34M | $-2.34M |
| Kaye Edward M. MD | director | 0 | $0 | 6 | $3.44M | $-3.44M |
| Blum Robert I | President & CEO | 0 | $0 | 19 | $7.69M | $-7.69M |
| Callos Andrew | EVP, Chief Commercial Officer | 0 | $0 | 18 | $11.28M | $-11.28M |
Cytokinetics, Incorporated, a late-stage biopharmaceutical company, focuses on discovering, developing, and commercializing muscle activators and inhibitors as potential treatments for debilitating diseases. The company develops small molecule drug candidates primarily engineered to impact muscle function and contractility. Its drug candidates include omecamtiv mecarbil, a novel cardiac myosin activator that is in Phase III clinical trial in patients with heart failure; and reldesemtiv, a skeletal muscle troponin activator, which is in Phase III clinical trial to treat amyotrophic lateral sclerosis and spinal muscular atrophy. The company also develops CK-136, a novel cardiac troponin activator that is in Phase I clinical trial; aficamten, a novel cardiac myosin inhibitor, which is in Phase III clinical trial for the treatment of patients with symptomatic obstructive hypertrophic cardiomyopathy; and CK-3772271, a small molecule cardiac myosin inhibitor that is in Phase I clinical trial. Cytokinetics, Incorporated has a strategic alliance with Astellas Pharma Inc. The company was incorporated in 1997 and is headquartered in South San Francisco, California.
Over the last 12 months, insiders at Cytokinetics, Incorporated have bought $0 and sold $27.23M worth of Cytokinetics, Incorporated stock.
On average, over the past 5 years, insiders at Cytokinetics, Incorporated have bought $0 and sold $21.9M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 118,413 shares for transaction amount of $1.13M was made by BVF PARTNERS L P/IL (10 percent owner) on 2019‑12‑11.
| 2026-03-05 | Sale | Callos Andrew | EVP, Chief Commercial Officer | 26,000 0.0212% | $61.87 | $1.61M | -0.38% | |
| 2026-03-02 | Sale | Callos Andrew | EVP, Chief Commercial Officer | 886 0.0007% | $61.62 | $54,595 | -0.86% | |
| 2026-03-02 | Sale | PARSHALL B LYNNE | director | 5,000 0.004% | $61.21 | $306,050 | -0.86% | |
| 2026-02-05 | Sale | Callos Andrew | EVP, Chief Commercial Officer | 15,000 0.0126% | $61.93 | $928,950 | +2.33% | |
| 2026-02-02 | Sale | Callos Andrew | EVP, Chief Commercial Officer | 886 0.0007% | $62.10 | $55,021 | -1.10% | |
| 2026-01-05 | Sale | Callos Andrew | EVP, Chief Commercial Officer | 15,000 0.0124% | $60.28 | $904,200 | +4.68% | |
| 2026-01-02 | Sale | Callos Andrew | EVP, Chief Commercial Officer | 1,798 0.0015% | $62.62 | $112,585 | +3.82% | |
| 2025-12-29 | Sale | Callos Andrew | EVP, Chief Commercial Officer | 1,809 0.0015% | $62.44 | $112,954 | +3.70% | |
| 2025-12-22 | Sale | WIERENGA WENDELL | director | 20,000 0.0169% | $66.14 | $1.32M | -2.46% | |
| 2025-12-16 | Sale | Malik Fady Ibraham | EVP Research & Development | 2,200 0.0018% | $61.24 | $134,728 | +3.04% | |
| 2025-12-08 | Sale | Callos Andrew | EVP, Chief Commercial Officer | 1,042 0.0009% | $65.96 | $68,730 | -1.21% | |
| 2025-12-05 | Sale | Callos Andrew | EVP, Chief Commercial Officer | 52,486 0.0443% | $65.95 | $3.46M | -3.52% | |
| 2025-12-02 | Sale | Malik Fady Ibraham | EVP Research & Development | 2,200 0.0019% | $63.89 | $140,558 | +0.28% | |
| 2025-12-02 | Sale | HENDERSON JOHN T | director | 8,750 0.0074% | $63.90 | $559,125 | +0.28% | |
| 2025-12-01 | Sale | Harrington Robert Arthur | director | 2,150 0.0018% | $66.80 | $143,620 | -3.80% | |
| 2025-12-01 | Sale | Kaye Edward M. MD | director | 28,064 0.0238% | $66.72 | $1.87M | -3.80% | |
| 2025-11-19 | Sale | PARSHALL B LYNNE | director | 5,000 0.0042% | $64.73 | $323,650 | -1.24% | |
| 2025-11-18 | Sale | Malik Fady Ibraham | EVP Research & Development | 2,200 0.0019% | $66.45 | $146,190 | -3.26% | |
| 2025-11-11 | Sale | Kaye Edward M. MD | director | 5,175 0.0047% | $65.08 | $336,789 | -3.59% | |
| 2025-11-04 | Sale | Malik Fady Ibraham | EVP Research & Development | 2,295 0.0018% | $59.55 | $136,667 | +7.46% |
| Blum Robert I | President & CEO | 358108 0.2929% | $21.63M | 0 | 223 | |
| Malik Fady Ibraham | EVP Research & Development | 138552 0.1133% | $8.37M | 0 | 109 | |
| HENDERSON JOHN T | director | 74578 0.061% | $4.51M | 1 | 13 | +75.35% |
| Callos Andrew | EVP, Chief Commercial Officer | 50440 0.0413% | $3.05M | 0 | 19 | |
| WIERENGA WENDELL | director | 32444 0.0265% | $1.96M | 0 | 1 | |
| WIERENGA WENDALL | director | 24848 0.0203% | $1.5M | 0 | 10 | |
| Bhanji Muna | director | 23510 0.0192% | $1.42M | 0 | 3 | |
| Harrington Robert Arthur | director | 18542 0.0152% | $1.12M | 0 | 6 | |
| PARSHALL B LYNNE | director | 17933 0.0147% | $1.08M | 0 | 15 | |
| Kaye Edward M. MD | director | 9977 0.0082% | $602,710.57 | 0 | 9 | |
| SCHMERTZLER MICHAEL | director | 4340923 3.5504% | $262.24M | 1 | 8 | +68.65% |
| Eastern Capital LTD | 10 percent owner | 2883845 2.3587% | $174.21M | 1 | 0 | |
| DOW STEPHEN M | director | 1421052 1.1623% | $85.85M | 9 | 1 | <0.0001% |
| BVF PARTNERS L P/IL | 463244 0.3789% | $27.98M | 2 | 2 | +74.11% | |
| SPUDICH JAMES A | director | 180600 0.1477% | $10.91M | 0 | 24 | |
| Cragg David | Chief HR & Admin Officer | 138704 0.1134% | $8.38M | 0 | 7 | |
| SCHLOSSBERG MARK A | SVP - Legal & General Counsel | 103408 0.0846% | $6.25M | 0 | 4 | |
| HEIDRICH A GRANT III | director | 93755 0.0767% | $5.66M | 0 | 3 | |
| Jaw Ching | SVP Finance & CFO | 67184 0.0549% | $4.06M | 0 | 6 | |
| Morgan Bradley Paul | SVP Drug Discovery & Early Dev | 46441 0.038% | $2.81M | 0 | 1 | |
| MORGANS DAVID J JR | EVP-Preclinical R&D | 42000 0.0344% | $2.54M | 0 | 27 | |
| GAGE L PATRICK | director | 28932 0.0237% | $1.75M | 4 | 8 | +19.97% |
| WOLFF ANDREW A | SVP & CMO | 21261 0.0174% | $1.28M | 0 | 1 | |
| TRAUTMAN JAY K | VP, Discovery Research | 17896 0.0146% | $1.08M | 0 | 14 | |
| Wong Robert | VP, Chief Accounting Officer | 16653 0.0136% | $1.01M | 0 | 4 | |
| McDowell Caryn Gordon | GC & Chief Compliance Officer | 15000 0.0123% | $906,150.00 | 0 | 5 | |
| SMITH SANDFORD D | 12170 0.01% | $735,189.70 | 0 | 18 | ||
| COSTA SANTO J | 10000 0.0082% | $604,100.00 | 0 | 8 | ||
| Sabry James H | 0 0% | $0 | 0 | 41 |
$211,610,344 | 91 | 38.45% | $9.83B | |
$108,876,545 | 67 | 72.81% | $7.95B | |
$19,233,721 | 36 | 70.14% | $11.14B | |
$477,065,869 | 34 | 82.05% | $5.43B | |
$1,801,511 | 23 | 18.58% | $8.38B | |
Cytokinetics, Incorporated (CYTK) | $11,859,102 | 17 | 18.62% | $7.39B |
$103,944,213 | 17 | 5.95% | $6.39B | |
$1,279,017 | 16 | 51.12% | $8.3B | |
$74,605,681 | 14 | 47.06% | $5.42B | |
$75,296,863 | 13 | 33.79% | $6.82B | |
$9,976,473 | 12 | 29.52% | $6.57B | |
$11,898,979 | 10 | 54.58% | $7.42B | |
$35,908,794 | 10 | 126.31% | $5.88B | |
$20,499,451 | 9 | 71.54% | $6.02B | |
$55,713,031 | 8 | -0.36% | $8.91B | |
$948,235 | 8 | 15.56% | $8.43B | |
$182,500,000 | 6 | 29.00% | $6.69B | |
$105,414,951 | 5 | 10.07% | $7.27B | |
$41,376,000 | 4 | -12.07% | $8.53B |
| Increased Positions | 252 | +60.14% | 11M | +7.41% |
| Decreased Positions | 184 | -43.91% | 14M | -9.82% |
| New Positions | 106 | New | 3M | New |
| Sold Out Positions | 47 | Sold Out | 3M | Sold Out |
| Total Postitions | 487 | +16.23% | 139M | -2.41% |
| T. Rowe Price Investment Management, Inc. | $1.18M | 15.64% | 19.08M | +1M | +8.4% | 2025-09-30 |
| Blackrock, Inc. | $958,404.00 | 12.73% | 15.53M | -152,120 | -0.97% | 2025-09-30 |
| Fmr Llc | $808,147.00 | 10.73% | 13.09M | +2M | +16.19% | 2025-09-30 |
| Vanguard Group Inc | $731,920.00 | 9.72% | 11.86M | -127,043 | -1.06% | 2025-09-30 |
| Wellington Management Group Llp | $457,330.00 | 6.07% | 7.41M | -419,118 | -5.35% | 2025-09-30 |
| State Street Corp | $346,758.00 | 4.6% | 5.62M | -755,419 | -11.85% | 2025-09-30 |
| Deep Track Capital, Lp | $265,439.00 | 3.53% | 4.3M | +650,000 | +17.81% | 2025-09-30 |
| Bank Of America Corp /De/ | $189,005.00 | 2.51% | 3.06M | +416,228 | +15.73% | 2025-09-30 |
| Geode Capital Management, Llc | $187,672.00 | 2.49% | 3.04M | +45,757 | +1.53% | 2025-09-30 |
| Polar Capital Holdings Plc | $171,790.00 | 2.28% | 2.78M | -15,471 | -0.55% | 2025-09-30 |