Krystal Biotech, Inc., a clinical stage biotechnology company, engages in the field of redosable gene therapy to treat serious rare diseases in the United States. Its lead product candidate is beremagene geperpavec (B-VEC), which is in Phase III clinical study to treat dystrophic epidermolysis bullosa. The company is also involved in developing KB105 that is in Phase I/II clinical study for treating patients with deficient autosomal recessive congenital ichthyosis; KB301, which is in Phase I/II clinical stage for treating wrinkles and other presentations of aged or damaged skin; KB407 that is in preclinical stage for cystic fibrosis; and KB104, which is in preclinical stage for netherton syndrome. Its discovery stage product candidates include KB5xx for treating chronic skin diseases, KB3xx to treat aesthetic skin conditions, and KB3xx product. Krystal Biotech, Inc. was founded in 2015 and is headquartered in Pittsburgh, Pennsylvania.
Over the last 12 months, insiders at Krystal Biotech, Inc. have bought $0 and sold $68.45M worth of Krystal Biotech, Inc. stock.
On average, over the past 5 years, insiders at Krystal Biotech, Inc. have bought $0 and sold $35.07M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 50,000 shares for transaction amount of $1M was made by Krishnan Suma (Chief Operating Officer) on 2018‑10‑18.
2024-06-11 | Sale | Krishnan Suma | President, R&D | 50,000 0.1734% | $175.76 | $8.79M | +0.17% | |
2024-06-11 | Sale | Krishnan Krish S | President and CEO | 50,000 0.1734% | $175.76 | $8.79M | +0.17% | |
2024-05-20 | Sale | Gangolli Julian S | director | 20,000 0.0699% | $164.13 | $3.28M | +2.49% | |
2024-03-11 | Sale | Krishnan Suma | President, R&D | 50,000 0.1773% | $170.95 | $8.55M | -1.64% | |
2024-03-11 | Sale | Krishnan Krish S | President and CEO | 50,000 0.1773% | $170.95 | $8.55M | -1.64% | |
2024-02-28 | Sale | ROMANO KATHRYN | Chief Accounting Officer | 12,200 0.0438% | $165.94 | $2.02M | +3.48% | |
2024-02-28 | Sale | ROMANO KATHRYN | Chief Accounting Officer | 11,997 0.0431% | $165.88 | $1.99M | +3.48% | |
2024-02-28 | Sale | ROMANO KATHRYN | Chief Accounting Officer | 10,600 0.0381% | $166.10 | $1.76M | +3.48% | |
2024-02-26 | Sale | ROMANO KATHRYN | Chief Accounting Officer | 8,087 0.025% | $136.91 | $1.11M | +7.49% | |
2024-01-22 | Sale | Romano Kathryn | Chief Accounting Officer | 2,500 0.0088% | $130.00 | $325,000 | +25.17% | |
2023-12-11 | Sale | Krishnan Suma | President, R&D | 50,000 0.1761% | $105.67 | $5.28M | +50.45% | |
2023-12-11 | Sale | Krishnan Krish S | President and CEO | 50,000 0.1761% | $105.67 | $5.28M | +50.45% | |
2023-09-11 | Sale | Krishnan Suma | President, R&D | 50,000 0.1769% | $127.23 | $6.36M | -2.54% | |
2023-09-11 | Sale | Krishnan Krish S | President and CEO | 50,000 0.1769% | $127.23 | $6.36M | -2.54% | |
2023-06-09 | Sale | JANNEY DANIEL | director | 18,935 0.0736% | $128.77 | $2.44M | -4.32% | |
2023-06-09 | Sale | ORTH ANDREW C. | Chief Commercial Officer | 12,500 0.0485% | $128.61 | $1.61M | -4.32% | |
2023-06-08 | Sale | JANNEY DANIEL | director | 31,065 0.1209% | $128.11 | $3.98M | -3.61% | |
2023-05-31 | Sale | Krishnan Suma | President, R&D | 50,000 0.1917% | $116.20 | $5.81M | +4.58% | |
2023-05-31 | Sale | Krishnan Krish S | President and CEO | 50,000 0.1917% | $116.20 | $5.81M | +4.58% | |
2023-05-22 | Sale | Romano Kathryn | Chief Accounting Officer | 25,000 0.0902% | $109.04 | $2.73M | +3.44% |
Krishnan Suma | President, R&D | 1525882 5.581% | $182.19 | 4 | 26 | +56.24% |
Krishnan Krish S | President and CEO | 1525882 5.581% | $182.19 | 3 | 23 | +37.18% |
ROMANO KATHRYN | Chief Accounting Officer | 12936 0.0445% | $182.19 | 0 | 7 | |
Gangolli Julian S | director | 0 0% | $182.19 | 0 | 1 | |
JANNEY DANIEL | director | 107362 0.3806% | $182.19 | 1 | 8 | +1.89% |
ROSSI DINO A | director | 83691 0.2967% | $182.19 | 0 | 1 | |
NORBY R DOUGLAS | director | 9000 0.0319% | $182.19 | 1 | 0 | +106.7% |
Riley Antony A | Chief Financial Officer | 2800 0.0099% | $182.19 | 1 | 0 | +100% |
ORTH ANDREW C. | Chief Commercial Officer | 100 0.0004% | $182.19 | 0 | 1 |
Fidelity Investments | $755.12M | 14.86 | 4.24M | +77.87% | +$330.59M | 0.05 | |
Avoro Capital Advisors Llc | $454.71M | 8.95 | 2.56M | -0.39% | -$1.78M | 5.45 | |
The Vanguard Group | $432.86M | 8.52 | 2.43M | -0.12% | -$532,900.35 | 0.01 | |
BlackRock | $321.23M | 6.32 | 1.81M | -0.23% | -$741,612.24 | 0.01 | |
Redmile Group | $268.36M | 5.28 | 1.51M | -12.98% | -$40.02M | 9.94 | |
Frazier Life Sciences Management L P | $175.88M | 3.46 | 988,460 | 0% | +$0 | 9.03 | |
State Street | $168.06M | 3.31 | 944,547 | -23.67% | -$52.12M | 0.01 | |
JENNISON ASSOCIATES LLC | $119.34M | 2.35 | 670,735 | -7.4% | -$9.54M | 0.08 | |
T. Rowe Price | $117.19M | 2.31 | 658,618 | +54.11% | +$41.15M | 0.01 | |
Dimensional Fund Advisors | $101.94M | 2.01 | 572,915 | +4.01% | +$3.93M | 0.03 | |
Geode Capital Management | $93.56M | 1.84 | 525,745 | +2.84% | +$2.58M | 0.01 | |
Hood River Capital Management LLC | $88.18M | 1.74 | 495,586 | +8.09% | +$6.6M | 1.97 | |
Lord Abbett | $87.58M | 1.72 | 492,232 | -20.41% | -$22.46M | 0.31 | |
Goldman Sachs | $77.32M | 1.52 | 434,574 | +90.56% | +$36.75M | 0.02 | |
Nuveen | $58.79M | 1.16 | 330,442 | +4.75% | +$2.66M | 0.02 | |
Credit Suisse | $57.28M | 1.13 | 321,946 | -32.15% | -$27.14M | 0.05 | |
Woodline Partners LP | $49.01M | 0.97 | 275,455 | -42.85% | -$36.75M | 0.46 | |
Morgan Stanley | $38.94M | 0.77 | 218,829 | -31.56% | -$17.95M | <0.01 | |
SEB | $38.74M | 0.76 | 217,747 | -10.78% | -$4.68M | 0.19 | |
Northern Trust | $36.49M | 0.72 | 205,078 | -1.97% | -$733,249.52 | 0.01 | |
Charles Schwab | $33.61M | 0.66 | 188,903 | +2.09% | +$687,699.43 | 0.01 | |
Braidwell Lp | $31.51M | 0.62 | 177,089 | -9.74% | -$3.4M | 1.78 | |
JPMorgan Chase | $31.16M | 0.61 | 175,126 | -17.98% | -$6.83M | <0.01 | |
Baker Bros Advisors LP | $30.24M | 0.6 | 169,934 | 0% | +$0 | 0.38 | |
Allspring Global Investments | $28.19M | 0.56 | 158,425 | +167.05% | +$17.63M | 0.04 | |
Eventide Asset Management | $24.28M | 0.48 | 136,485 | 0% | +$0 | 0.38 | |
C Worldwide Group Holding A S | $24.16M | 0.48 | 135,809 | -26.91% | -$8.9M | 0.28 | |
Victory Capital Management Inc | $23.99M | 0.47 | 134,820 | -22.02% | -$6.77M | 0.02 | |
Franklin Templeton Investments | $23.39M | 0.46 | 131,465 | +395.24% | +$18.67M | 0.01 | |
Balyasny Asset Management Llc | $22.1M | 0.44 | 124,203 | -51.6% | -$23.56M | 0.06 | |
Driehaus Capital Management LLC | $19.61M | 0.39 | 110,199 | -43.89% | -$15.34M | 0.2 | |
Handelsbanken | $18.72M | 0.37 | 105,200 | -14.61% | -$3.2M | 0.08 | |
ROCK SPRINGS CAPITAL MANAGEMENT, LP | $18.5M | 0.36 | 103,969 | 0% | +$0 | 0.47 | |
Susquehanna International Group | $18.07M | 0.36 | 101,557 | +1,162.83% | +$16.64M | 0.02 | |
Capital World Investors | $17.29M | 0.34 | 97,147 | New | +$17.29M | <0.01 | |
TimesSquare Capital Management LLC | $17.29M | 0.34 | 97,161 | -61.21% | -$27.28M | 0.25 | |
Man Group Plc | $17.06M | 0.34 | 95,858 | +88.56% | +$8.01M | 0.04 | |
Jane Street Capital | $16.68M | 0.33 | 93,745 | +85.2% | +$7.67M | 0.02 | |
S Squared Technology LLC | $16.05M | 0.32 | 90,215 | -18.15% | -$3.56M | 7.42 | |
BNY Mellon | $15.99M | 0.32 | 89,839 | -8.93% | -$1.57M | <0.01 | |
Invesco | $15.95M | 0.31 | 89,628 | +65.28% | +$6.3M | <0.01 | |
Soleus Capital Management, L.P. | $14.96M | 0.29 | 84,100 | +110.25% | +$7.85M | 0.14 | |
D. E. Shaw & Co. | $14.6M | 0.29 | 82,027 | +22.17% | +$2.65M | 0.02 | |
Integral Health Asset Management Llc | $14.23M | 0.28 | 80,000 | -5.88% | -$889,650.00 | 1.41 | |
Bank of America | $13.49M | 0.27 | 75,844 | -16.83% | -$2.73M | <0.01 | |
Td Asset Management Inc | $12.31M | 0.24 | 69,162 | +68.84% | +$5.02M | 0.01 | |
Verition Fund Management Llc | $11M | 0.22 | 61,800 | -35.6% | -$6.08M | 0.12 | |
Voya Investment Management LLC | $10.49M | 0.21 | 58,981 | +28.63% | +$2.34M | 0.01 | |
Millennium Management LLC | $10.08M | 0.2 | 56,635 | +564.65% | +$8.56M | 0.01 | |
Rafferty Asset Management Llc | $9.5M | 0.19 | 53,367 | -36.48% | -$5.45M | 0.03 |