Krystal Biotech, Inc. (KRYS) Insider Trading Activity

NASDAQ$276.45
Market Cap
$8.02B
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
657 of 888
Rank in Industry
381 of 508

KRYS Insider Trading Activity

KRYS Median Price and Trade Amounts History Chart

Statistics of Insider Transactions

Amount of Insider Buys and Sells

Buys
$0
0
0
Sells
$63,714,866
19
100

Related Transactions

ROMANO KATHRYNChief Accounting Officer
0
$0
2
$3.53M
$-3.53M
Krishnan SumaPresident, R&D
0
$0
7
$27.41M
$-27.41M
Krishnan Krish SPresident and CEO
0
$0
10
$32.77M
$-32.77M

About Krystal Biotech, Inc.

Krystal Biotech, Inc., a clinical stage biotechnology company, engages in the field of redosable gene therapy to treat serious rare diseases in the United States. Its lead product candidate is beremagene geperpavec (B-VEC), which is in Phase III clinical study to treat dystrophic epidermolysis bullosa. The company is also involved in developing KB105 that is in Phase I/II clinical study for treating patients with deficient autosomal recessive congenital ichthyosis; KB301, which is in Phase I/II clinical stage for treating wrinkles and other presentations of aged or damaged skin; KB407 that is in preclinical stage for cystic fibrosis; and KB104, which is in preclinical stage for netherton syndrome. Its discovery stage product candidates include KB5xx for treating chronic skin diseases, KB3xx to treat aesthetic skin conditions, and KB3xx product. Krystal Biotech, Inc. was founded in 2015 and is headquartered in Pittsburgh, Pennsylvania.

Insider Activity of Krystal Biotech, Inc.

Over the last 12 months, insiders at Krystal Biotech, Inc. have bought $0 and sold $63.71M worth of Krystal Biotech, Inc. stock.

On average, over the past 5 years, insiders at Krystal Biotech, Inc. have bought $0 and sold $50.26M worth of stock each year.

There was no buying activity among insiders over the last 12 months.

The last purchase of 50,000 shares for transaction amount of $1M was made by Krishnan Suma (Chief Operating Officer) on 2018‑10‑18.

List of Insider Buy and Sell Transactions, Krystal Biotech, Inc.

2026-02-09SaleROMANO KATHRYNChief Accounting Officer
12,500
0.043%
$272.14
$3.4M
-0.07%
2025-12-04SaleKrishnan SumaPresident, R&D
50,000
0.171%
$220.15
$11.01M
+18.50%
2025-12-04SaleKrishnan Krish SPresident and CEO
50,000
0.171%
$220.15
$11.01M
+18.50%
2025-07-16SaleKrishnan SumaPresident, R&D
2,918
0.0101%
$150.00
$437,700
+28.59%
2025-07-16SaleKrishnan Krish SPresident and CEO
2,918
0.0101%
$150.00
$437,700
+28.59%
2025-07-15SaleKrishnan Krish SPresident and CEO
2,184
0.0077%
$150.68
$329,089
+29.89%
2025-07-15SaleKrishnan SumaPresident, R&D
6,120
0.0216%
$150.99
$924,061
+29.89%
2025-07-15SaleKrishnan Krish SPresident and CEO
6,120
0.0216%
$150.99
$924,061
+29.89%
2025-07-14SaleKrishnan Krish SPresident and CEO
13,400
0.0463%
$150.30
$2.01M
+26.84%
2025-07-14SaleKrishnan SumaPresident, R&D
26,835
0.0928%
$150.30
$4.03M
+26.84%
2025-07-14SaleKrishnan Krish SPresident and CEO
26,835
0.0928%
$150.30
$4.03M
+26.84%
2025-07-10SaleKrishnan SumaPresident, R&D
13,727
0.0477%
$150.27
$2.06M
+27.04%
2025-07-10SaleKrishnan Krish SPresident and CEO
13,727
0.0477%
$150.27
$2.06M
+27.04%
2025-07-09SaleKrishnan SumaPresident, R&D
400
0.0014%
$150.10
$60,042
+27.66%
2025-07-09SaleKrishnan Krish SPresident and CEO
400
0.0014%
$150.10
$60,042
+27.66%
2025-03-13SaleKrishnan Krish SPresident and CEO
16,975
0.0589%
$177.27
$3.01M
-4.65%
2025-03-13SaleKrishnan SumaPresident, R&D
50,000
0.174%
$177.79
$8.89M
-4.65%
2025-03-13SaleKrishnan Krish SPresident and CEO
50,000
0.174%
$177.79
$8.89M
-4.65%
2025-02-27SaleROMANO KATHRYNChief Accounting Officer
750
0.0026%
$175.22
$131,415
-1.03%
2024-12-13SaleKrishnan SumaPresident, R&D
50,000
0.1739%
$164.80
$8.24M
-2.38%
Total: 100
*Gray background shows transactions not older than one year

Insider Historical Profitability

54.58%
Krishnan Krish SPresident and CEO
1413711
4.8753%
$390.82M335
+37.28%
Krishnan SumaPresident, R&D
1413711
4.8753%
$390.82M435
+56.29%
ROMANO KATHRYNChief Accounting Officer
19318
0.0666%
$5.34M09
JANNEY DANIELdirector
107362
0.3702%
$29.68M18
+2.09%
ROSSI DINO Adirector
83691
0.2886%
$23.14M01
NORBY R DOUGLASdirector
9000
0.031%
$2.49M10
+106.7%
Riley Antony AChief Financial Officer
2800
0.0097%
$774,060.0010
+100%
ORTH ANDREW C.Chief Commercial Officer
100
0.0003%
$27,645.0001
Gangolli Julian Sdirector
0
0%
$001
*Gray background shows insiders who have made transactions during last year

Historical Insider Profitability vs. Competitors

$211,610,344
91
38.45%
$10.55B
$108,876,545
67
72.81%
$9.34B
$88,307,390
38
-1.70%
$10.11B
$1,801,511
23
18.58%
$8.94B
$103,944,213
17
5.95%
$6.54B
$11,859,102
17
18.62%
$8.1B
$1,279,017
16
51.12%
$9.14B
$627,701,115
15
145.68%
$11.14B
$57,686,748
13
21.11%
$5.58B
$75,296,863
13
33.79%
$6.5B
$9,976,473
12
29.52%
$6.71B
$2,477,801
11
4.98%
$5.48B
Krystal Biotech, Inc.
(KRYS)
$11,898,979
10
54.58%
$8.02B
$20,499,451
9
71.54%
$5.55B
$55,713,031
8
-0.36%
$5.86B
$948,235
8
15.56%
$9.38B
$105,414,951
5
10.07%
$7.33B
$41,376,000
4
-12.07%
$7.68B
$36,900,000
3
-9.12%
$10.99B

KRYS Institutional Investors: Active Positions

Increased Positions165+56.9%2M+7.85%
Decreased Positions123-42.41%1M-5.33%
New Positions51New197,567New
Sold Out Positions29Sold Out348,630Sold Out
Total Postitions332+14.48%28M+2.53%

KRYS Ownership Change vs Market

Institutional Investor Ownership

Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
Active Shareholders
Fmr Llc$1.07M14.97%4.34M+6,686+0.15%2025-09-30
Blackrock, Inc.$946,685.0013.22%3.83M-11,027-0.29%2025-09-30
Vanguard Group Inc$689,424.009.63%2.79M-30,680-1.09%2025-09-30
Avoro Capital Advisors Llc$685,861.009.58%2.78M+117,777+4.43%2025-09-30
State Street Corp$344,678.004.81%1.4M+40,621+3%2025-09-30
Soleus Capital Management, L.P.$251,560.003.51%1.02M+95,873+10.39%2025-09-30
Capital World Investors$199,809.002.79%809,240-133,009-14.12%2025-09-30
Frazier Life Sciences Management, L.P.$169,988.002.37%688,46000%2025-09-30
Redmile Group, Llc$163,303.002.28%661,388-2,083-0.31%2025-09-30
Citadel Advisors Llc$157,279.002.2%636,988+602,428+1,743.14%2025-09-30

Financial Ratios

Summary
Comparison with Competitors

Price to Earnings

Price/Earnings to Growth

Price to Sales

Price to Book

Price/Free Cash Flow

Analyst Recommendations

Analyst Price Targets

Prismo does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.
Information is provided 'as-is' and solely for informational purposes and is not advice. Prismo does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.