| $337M | ||
| $259M | ||
| $100M | ||
| $79M | ||
| $60M | ||
| $58M |
Buys | $386,226 | 8 | 47 |
Sells | $233,750 | 9 | 53 |
| RTW INVESTMENTS, LP | 10 percent owner | 2 | $275,701 | 0 | $0 | $275,701 |
| Hochman David P | See Remarks | 5 | $105,695 | 0 | $0 | $105,695 |
| Taylor Andrew Lawrence | Chief Financial Officer | 1 | $4,830 | 0 | $0 | $4,830 |
| Fain Eric S | director | 0 | $0 | 4 | $38,849 | $-38,849 |
| Sherman Darren | See Remarks | 0 | $0 | 5 | $194,901 | $-194,901 |
Orchestra BioMed Holdings, Inc. operates as a biomedical innovation company. The company's flagship product candidates include BackBeat Cardiac Neuromodulation Therapy (CNT) for the treatment of hypertension; and Virtue Sirolimus AngioInfusion Balloon (SAB) for the treatment of atherosclerotic artery disease. Its products also comprise FreeHold retractors that are minimally invasive surgical device solutions. The company has a strategic collaboration with Medtronic for the development and commercialization of BackBeat CNT for the treatment of hypertension in pacemaker-indicated patients; and a strategic partnership with Terumo Corporation for the development and commercialization of Virtue SAB for the treatment of artery disease. Orchestra BioMed Holdings, Inc. is based in New Hope, Pennsylvania.
Over the last 12 months, insiders at Orchestra BioMed Holdings, Inc. have bought $386,226 and sold $233,750 worth of Orchestra BioMed Holdings, Inc. stock.
On average, over the past 5 years, insiders at Orchestra BioMed Holdings, Inc. have bought $223,063 and sold $233,750 worth of stock each year.
Highest buying activity among insiders over the last 12 months: RTW INVESTMENTS, LP (10 percent owner) — $275,701. Hochman David P (See Remarks) — $105,695. Taylor Andrew Lawrence (Chief Financial Officer) — $4,830.
The last purchase of 49,900 shares for transaction amount of $149,201 was made by RTW INVESTMENTS, LP (10 percent owner) on 2025‑04‑30.
| 2025-06-26 | Sale | Fain Eric S | director | 2,683 0.0072% | $3.05 | $8,183 | -1.34% | |
| 2025-04-30 | RTW INVESTMENTS, LP | 10 percent owner | 49,900 0.1311% | $2.99 | $149,201 | -0.84% | ||
| 2025-04-29 | RTW INVESTMENTS, LP | 10 percent owner | 50,000 0.1305% | $2.53 | $126,500 | +16.60% | ||
| 2024-12-23 | Hochman David P | See Remarks | 4,000 0.0107% | $4.66 | $18,640 | -29.10% | ||
| 2024-12-19 | Taylor Andrew Lawrence | Chief Financial Officer | 1,000 0.0026% | $4.83 | $4,830 | -30.42% | ||
| 2024-12-18 | Hochman David P | See Remarks | 5,000 0.0145% | $4.91 | $24,550 | -29.83% | ||
| 2024-09-25 | Hochman David P | See Remarks | 7,500 0.0166% | $4.75 | $35,630 | -0.75% | ||
| 2024-09-24 | Hochman David P | See Remarks | 2,500 0.0057% | $4.91 | $12,275 | +1.74% | ||
| 2024-09-10 | Sale | Sherman Darren | See Remarks | 6,904 0.0171% | $5.31 | $36,660 | -14.96% | |
| 2024-09-10 | Sale | Fain Eric S | director | 1,800 0.0045% | $5.34 | $9,612 | -14.96% | |
| 2024-09-09 | Sale | Sherman Darren | See Remarks | 6,804 0.0174% | $5.48 | $37,286 | -14.34% | |
| 2024-09-09 | Sale | Fain Eric S | director | 1,800 0.0046% | $5.43 | $9,774 | -14.34% | |
| 2024-09-06 | Sale | Sherman Darren | See Remarks | 6,819 0.018% | $5.65 | $38,527 | -15.86% | |
| 2024-09-06 | Sale | Fain Eric S | director | 2,000 0.0053% | $5.64 | $11,280 | -15.86% | |
| 2024-09-05 | Sale | Sherman Darren | See Remarks | 6,961 0.019% | $5.85 | $40,722 | -18.13% | |
| 2024-09-04 | Sale | Sherman Darren | See Remarks | 6,837 0.0195% | $6.10 | $41,706 | -22.22% | |
| 2024-08-14 | Hochman David P | See Remarks | 2,500 0.0068% | $5.84 | $14,600 | -12.82% | ||
| 2024-06-25 | Hochman David P | See Remarks | 1,000 0.0032% | $6.95 | $6,950 | -23.80% | ||
| 2024-05-30 | Little William Reed | See Remarks | 4,000 0.0131% | $7.00 | $28,000 | -19.34% | ||
| 2024-05-17 | Hochman David P | See Remarks | 3,000 0.0072% | $5.15 | $15,450 | +4.22% |
| RTW INVESTMENTS, LP | 10 percent owner | 8306063 21.6798% | $25.67M | 2 | 0 | |
| Sherman Darren | See Remarks | 765787 1.9988% | $2.37M | 0 | 5 | |
| Hochman David P | See Remarks | 579498 1.5126% | $1.79M | 8 | 0 | <0.0001% |
| Taylor Andrew Lawrence | Chief Financial Officer | 344960 0.9004% | $1.07M | 1 | 0 | |
| Fain Eric S | director | 50949 0.133% | $157,432.41 | 0 | 4 | |
| Little William Reed | See Remarks | 307859 0.8035% | $951,284.31 | 1 | 0 | <0.0001% |
$5,102,291 | 146 | 5.58% | $110.81M | |
$30,470,407 | 140 | 20.39% | $106.76M | |
$49,091,668 | 110 | 13.11% | $104.01M | |
$48,218,096 | 42 | 0.89% | $125.2M | |
$909,129 | 37 | 42.19% | $110.75M | |
$6,915,275 | 21 | -32.61% | $118.83M | |
$294,424,120 | 20 | 1.33% | $129.54M | |
$33,027,560 | 17 | -10.02% | $105.49M | |
$4,701,608 | 14 | -4.34% | $115.43M | |
$145,194 | 11 | -27.37% | $108.75M | |
$9,999,920 | 10 | -40.03% | $128.37M | |
$1,073,250 | 10 | 19.46% | $125.66M | |
$478,647 | 7 | 69.41% | $124.34M | |
$22,090,972 | 7 | -3.49% | $132.51M | |
$68,692,148 | 6 | -39.10% | $124.17M | |
$4,745,999 | 5 | -4.91% | $118.18M | |
$762,555 | 4 | -34.52% | $111.9M | |
Orchestra BioMed Holdings, Inc. (OBIO) | $59,900 | 4 | -5.37% | $118.39M |
$19,175,155 | 2 | 40.00% | $122.87M |
| Increased Positions | 23 | +35.94% | 240,331 | +1.23% |
| Decreased Positions | 24 | -37.5% | 604,257 | -3.09% |
| New Positions | 7 | New | 54,119 | New |
| Sold Out Positions | 7 | Sold Out | 419,149 | Sold Out |
| Total Postitions | 63 | -1.56% | 19M | -1.86% |
| Rtw Investments, Lp | $22,485.00 | 21.6% | 8.21M | +3 | 0% | 2024-12-31 |
| Perceptive Advisors Llc | $12,584.00 | 12.09% | 4.59M | 0 | 0% | 2024-12-31 |
| Blackrock, Inc. | $5,331.00 | 5.12% | 1.95M | -33,174 | -1.68% | 2025-03-31 |
| Vanguard Group Inc | $3,610.00 | 3.47% | 1.32M | +7,767 | +0.59% | 2024-12-31 |
| Geode Capital Management, Llc | $1,568.00 | 1.51% | 572,441 | +5,222 | +0.92% | 2024-12-31 |
| Price T Rowe Associates Inc /Md/ | $1,335.00 | 1.28% | 487,170 | -25,493 | -4.97% | 2024-12-31 |
| State Street Corp | $1,227.00 | 1.18% | 447,712 | +18,099 | +4.21% | 2024-12-31 |
| Boxer Capital, Llc | $653.00 | 0.63% | 238,193 | 0 | 0% | 2024-09-30 |
| Boxer Capital Management, Llc | $653.00 | 0.63% | 238,193 | +238,193 | New | 2024-12-31 |
| Northern Trust Corp | $649.00 | 0.62% | 236,761 | +5,725 | +2.48% | 2024-12-31 |