| $350M | ||
| $217M | ||
| $172M | ||
| $109M | ||
| $107M | ||
| $104M |
Buys | $231,991 | 8 | 53 |
Sells | $439,182 | 7 | 47 |
| Hochman David P | See Remarks | 4 | $101,250 | 0 | $0 | $101,250 |
| Fain Eric S | director | 1 | $82,600 | 0 | $0 | $82,600 |
| Aryeh Jason | director | 2 | $37,481 | 0 | $0 | $37,481 |
| Sherman Darren | See Remarks | 1 | $10,660 | 6 | $439,050 | $-428,390 |
| RTW INVESTMENTS, LP | 10 percent owner | 0 | $0 | 1 | $132 | $-132 |
Orchestra BioMed Holdings, Inc. operates as an innovative company in the biomedical sector. Its leading product candidates are BackBeat Cardiac Neuromodulation Therapy (CNT), designed to manage hypertension, and the Virtue Sirolimus AngioInfusion Balloon (SAB), aimed at treating atherosclerotic artery disease. The company's offerings also encompass FreeHold retractors, which are solutions for minimally invasive surgical procedures. Orchestra BioMed has formed key alliances to advance its products: a strategic collaboration with Medtronic …
Over the last 12 months, insiders at Orchestra BioMed Holdings, Inc. have bought $231,991 and sold $439,182 worth of Orchestra BioMed Holdings, Inc. stock.
On average, over the past 5 years, insiders at Orchestra BioMed Holdings, Inc. have bought $901,167 and sold $224,311 worth of stock each year.
Highest buying activity among insiders over the last 12 months: Hochman David P (See Remarks) — $101,250. Fain Eric S (director) — $82,600. Aryeh Jason (director) — $37,481.
The last purchase of 2,000 shares for transaction amount of $10,660 was made by Sherman Darren (See Remarks) on 2026‑08‑26.
| 2026-11-02 | Sale | Sherman Darren | See Remarks | 15,000 0.0237% | $5.74 | $86,100 | -3.14% | |
| 2026-10-01 | Sale | Sherman Darren | See Remarks | 15,000 0.0251% | $6.36 | $95,400 | -9.61% | |
| 2026-09-01 | Sale | Sherman Darren | See Remarks | 15,000 0.0253% | $4.94 | $74,100 | +18.98% | |
| 2026-08-26 | Sherman Darren | See Remarks | 2,000 0.0034% | $5.33 | $10,660 | +10.41% | ||
| 2026-08-03 | Sale | Sherman Darren | See Remarks | 15,000 0.0388% | $4.09 | $61,350 | +37.38% | |
| 2026-07-01 | Sale | Sherman Darren | See Remarks | 15,000 0.0249% | $4.27 | $64,050 | +26.28% | |
| 2026-06-01 | Sale | Sherman Darren | See Remarks | 15,000 0.0253% | $3.87 | $58,050 | +25.98% | |
| 2026-06-01 | Hochman David P | See Remarks | 5,000 0.0083% | $3.83 | $19,150 | +25.98% | ||
| 2026-05-18 | Aryeh Jason | director | 665 0.001% | $3.75 | $2,494 | +11.81% | ||
| 2026-05-15 | Hochman David P | See Remarks | 5,000 0.0085% | $3.77 | $18,850 | +19.22% | ||
| 2026-05-15 | Aryeh Jason | director | 8,971 0.0157% | $3.90 | $34,987 | +19.22% | ||
| 2026-05-14 | Fain Eric S | director | 20,000 0.0336% | $4.13 | $82,600 | +7.54% | ||
| 2026-04-27 | Sale | RTW INVESTMENTS, LP | 10 percent owner | 32 <0.0001% | $4.13 | $132 | +3.41% | |
| 2026-03-13 | Hochman David P | See Remarks | 10,000 0.0181% | $4.29 | $42,900 | +1.67% | ||
| 2025-11-14 | Hochman David P | See Remarks | 5,000 0.0086% | $4.07 | $20,350 | +9.14% | ||
| 2025-09-19 | Aryeh Jason | director | 1,000 0.0019% | $2.45 | $2,450 | +69.26% | ||
| 2025-08-25 | Sherman Darren | See Remarks | 3,000 0.0057% | $2.62 | $7,860 | +56.15% | ||
| 2025-08-25 | Taylor Andrew Lawrence | Chief Financial Officer | 2,000 0.0037% | $2.55 | $5,100 | +56.15% | ||
| 2025-08-25 | Fain Eric S | director | 5,760 0.0109% | $2.61 | $15,034 | +56.15% | ||
| 2025-08-21 | Hochman David P | See Remarks | 6,000 0.0111% | $2.49 | $14,940 | +62.25% |
| RTW INVESTMENTS, LP | 10 percent owner | 9556063 15.8989% | $53.13M | 2 | 1 | +38.51% |
| Sherman Darren | See Remarks | 1104402 1.8375% | $6.14M | 2 | 11 | +56.15% |
| Hochman David P | See Remarks | 1064029 1.7703% | $5.92M | 14 | 0 | +0.29% |
| Aryeh Jason | director | 118118 0.1965% | $656,736.08 | 3 | 0 | +69.26% |
| Fain Eric S | director | 91709 0.1526% | $509,902.04 | 2 | 4 | +56.15% |
| PERCEPTIVE ADVISORS LLC | 10 percent owner | 5292556 8.8055% | $29.43M | 1 | 0 | +63.52% |
| Taylor Andrew Lawrence | Chief Financial Officer | 482788 0.8032% | $2.68M | 2 | 0 | +11.83% |
| Little William Reed | See Remarks | 307859 0.5122% | $1.71M | 1 | 0 | <0.0001% |
$31,123,523 | 108 | 6.46% | $387.86M | |
$64,733,831 | 40 | 5.69% | $299.32M | |
$140,595,157 | 34 | 17.93% | $301.23M | |
Orchestra BioMed Holdings, Inc. (OBIO) | $2,471,510 | 19 | 17.33% | $334.18M |
$10,399,379 | 13 | 13.60% | $302.03M |
| Increased Positions | 40 | +74.07% | 2M | +10.12% |
| Decreased Positions | 21 | -38.89% | 3M | -13.01% |
| New Positions | 22 | New | 1M | New |
| Sold Out Positions | 5 | Sold Out | 1M | Sold Out |
| Total Postitions | 73 | +35.19% | 22M | -2.9% |
| Rtw Investments, Lp | $35,799.00 | 14.83% | 8.31M | +<1 | 0% | 2025-09-30 |
| Perceptive Advisors Llc | $22,811.00 | 9.45% | 5.29M | +700,000 | +15.24% | 2025-09-30 |
| Vanguard Group Inc | $6,387.00 | 2.65% | 1.48M | +324,558 | +28.04% | 2025-09-30 |
| Alyeska Investment Group, L.P. | $5,885.00 | 2.44% | 1.37M | +1M | New | 2025-09-30 |
| Pathstone Holdings, Llc | $4,336.00 | 1.8% | 1.01M | +1M | New | 2025-09-30 |
| Affinity Asset Advisors, Llc | $3,135.00 | 1.3% | 727,272 | +727,272 | New | 2025-09-30 |
| Blackrock, Inc. | $2,863.00 | 1.19% | 664,333 | -17,016 | -2.5% | 2025-09-30 |
| Knoll Capital Management, Llc | $1,962.00 | 0.81% | 455,128 | 0 | 0% | 2025-09-30 |
| Price T Rowe Associates Inc /Md/ | $1,817.00 | 0.75% | 421,612 | -16,757 | -3.82% | 2025-09-30 |
| Geode Capital Management, Llc | $1,667.00 | 0.69% | 386,799 | +84,717 | +28.04% | 2025-09-30 |