Omeros Corporation, a commercial-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting inflammation, complement-mediated diseases, cancers related to dysfunction of the immune system, and addictive and compulsive disorders. The company's clinical programs include Narsoplimab (OMS721/MASP-2) that has completed pivotal studies for hematopoietic stem-cell transplant-associated thrombotic microangiopathy (HSCT-TMA); that is in Phase III clinical trial for immunoglobulin A nephropathy (IgAN) and atypical hemolytic uremic syndrome (aHUS); and Phase II clinical trial to treat COVID-19. Its clinical programs also consist of PPAR? (OMS405) that is in Phase II to treat opioid and nicotine addiction; PDE7 (OMS527), which is in Phase I trial for treating addiction and compulsive disorders, and movement disorders; and MASP-3 (OMS906) that is in Phase I trial for paroxysmal nocturnal hemoglobinuria (PNH) and other alternative pathway disorders. The company's preclinical programs comprise MASP-2-small-molecule inhibitors used for the treatment of aHUS, IgAN, HSCT-TMA, and age-related macular degeneration; longer-acting second generation antibody targeting MASP-2; and MASP-3-small-molecule inhibitors to treat PNH and other alternative pathway disorders. Its preclinical programs also include GPR174 Inhibitors and Chimeric Antigen Receptor (CAR) T-Cell and Adoptive T-Cell Therapies for various cancers; and G protein-coupled receptor targets for treating immunologic, immuno-oncologic, metabolic, CNS, cardiovascular, musculoskeletal, and other disorders. The company was incorporated in 1994 and is headquartered in Seattle, Washington.
Over the last 12 months, insiders at Omeros Corporation have bought $40,500 and sold $0 worth of Omeros Corporation stock.
On average, over the past 5 years, insiders at Omeros Corporation have bought $40,500 and sold $1.61M worth of stock each year.
Highest buying activity among insiders over the last 12 months: Demopulos Gregory A MD (Chairman, CEO & President) — $25,200. Demopulos Peter A MD (director) — $15,300.
The last purchase of 15,000 shares for transaction amount of $25,200 was made by Demopulos Gregory A MD (Chairman, CEO & President) on 2023‑11‑17.
2023-11-17 | Demopulos Gregory A MD | Chairman, CEO & President | 15,000 0.0245% | $1.68 | $25,200 | +111.66% | ||
2023-11-15 | Demopulos Peter A MD | director | 10,000 0.0161% | $1.53 | $15,300 | +125.57% | ||
2023-05-22 | Sale | Cable Thomas J. | director | 5,000 0.0081% | $6.53 | $32,650 | -45.85% | |
2023-05-22 | Sale | HANISH ARNOLD C | director | 5,000 0.008% | $6.46 | $32,300 | -45.85% | |
2021-06-17 | Sale | Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | 36,857 0.0588% | $14.90 | $549,169 | -53.84% | |
2021-06-15 | Sale | Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | 36,856 0.0596% | $15.02 | $553,577 | -53.29% | |
2021-05-20 | Sale | Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | 36,856 0.0584% | $14.96 | $551,366 | -51.92% | |
2021-05-19 | Sale | Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | 36,857 0.0594% | $17.07 | $629,149 | -57.10% | |
2021-04-08 | Sale | Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | 35,206 0.0566% | $17.76 | $625,259 | -53.90% | |
2021-04-07 | Sale | Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | 37,407 0.0599% | $17.91 | $669,959 | -54.24% | |
2021-02-22 | Sale | JACOBSEN MICHAEL A | VP FINANCE AND CAO | 8,100 0.0134% | $23.28 | $188,568 | -34.89% | |
2021-02-19 | Sale | JACOBSEN MICHAEL A | VP FINANCE AND CAO | 10,000 0.0155% | $22.64 | $226,400 | -37.23% | |
2021-02-10 | Sale | JACOBSEN MICHAEL A | VP FINANCE AND CAO | 1,900 0.0031% | $22.49 | $42,731 | -32.76% | |
2021-01-19 | Sale | JACOBSEN MICHAEL A | VP FINANCE AND CAO | 9,500 0.0157% | $19.95 | $189,525 | -21.58% | |
2021-01-13 | Sale | Cable Thomas J. | director | 5,000 0.008% | $16.97 | $84,850 | -10.19% | |
2020-05-13 | Sale | Cable Thomas J. | director | 5,000 0.0093% | $14.40 | $71,999 | +4.28% | |
2019-12-03 | Sale | Cable Thomas J. | director | 20,000 0.0309% | $10.99 | $219,748 | -6.68% | |
2019-10-14 | Sale | Cable Thomas J. | director | 10,000 0.0205% | $15.12 | $151,180 | -7.99% | |
2018-08-31 | Sale | Kelbon Marcia S. | VP Patent and General Counsel | 15,058 0.0308% | $25.75 | $387,691 | -39.01% | |
2018-08-30 | Sale | Kelbon Marcia S. | VP Patent and General Counsel | 70,000 0.0825% | $14.28 | $999,250 | -36.44% |
Demopulos Peter A MD | director | 208516 0.3317% | $3.82 | 7 | 0 | <0.0001% |
Demopulos Gregory A MD | Chairman, CEO & President | 123945 0.1972% | $3.82 | 1 | 12 | |
Kelbon Marcia S. | VP Patent and General Counsel | 192645 0.3064% | $3.82 | 0 | 17 | |
Aspiri Ray | director | 186872 0.2973% | $3.82 | 1 | 0 | <0.0001% |
Cable Thomas J. | director | 35067 0.0558% | $3.82 | 0 | 20 | |
JACOBSEN MICHAEL A | VP FINANCE AND CAO | 14000 0.0223% | $3.82 | 0 | 11 | |
HANISH ARNOLD C | director | 0 0% | $3.82 | 1 | 1 | +0.81% |
Ingalls Snyder Llc | $16.21M | 8.11 | 4.7M | +3.33% | +$522,267.54 | 0.76 | |
BlackRock | $14.53M | 7.27 | 4.21M | -1.61% | -$237,063.30 | <0.0001 | |
The Vanguard Group | $11.21M | 5.61 | 3.25M | +2.57% | +$280,650.60 | <0.0001 | |
Stifel | $6.59M | 3.3 | 1.91M | +0.98% | +$63,669.86 | 0.01 | |
D. E. Shaw & Co. | $5.79M | 2.9 | 1.68M | +12.42% | +$639,560.96 | 0.01 | |
Geode Capital Management | $4.75M | 2.38 | 1.38M | +2.94% | +$135,821.75 | <0.0001 | |
State Street | $4.27M | 2.13 | 1.24M | +2.99% | +$123,951.59 | <0.0001 | |
Ci Private Wealth Llc | $2.15M | 1.08 | 623,663 | -6.03% | -$137,999.98 | <0.01 | |
Bank of Montreal | $1.98M | 0.97 | 563,096 | 0% | +$0 | <0.01 | |
Northern Trust | $1.91M | 0.96 | 554,108 | -0.88% | -$17,056.80 | <0.0001 | |
UBS | $1.86M | 0.93 | 538,682 | +8.93% | +$152,269.21 | <0.01 | |
Royal Bank of Canada | $1.85M | 0.93 | 537,232 | +5.56% | +$97,636.34 | <0.0001 | |
Charles Schwab | $1.74M | 0.87 | 504,369 | +7.5% | +$121,422.75 | <0.0001 | |
Nomura Holdings | $1.56M | 0.78 | 450,829 | +17.67% | +$233,513.24 | 0.01 | |
Morgan Stanley | $743,638.00 | 0.37 | 215,547 | -23.68% | -$230,660.36 | <0.0001 | |
BNY Mellon | $646,870.00 | 0.32 | 187,499 | -7.32% | -$51,111.63 | <0.0001 | |
Wellington Management Company | $616,923.00 | 0.31 | 178,818 | New | +$616,923.00 | <0.0001 | |
First Trust | $614,589.00 | 0.31 | 178,142 | +3.12% | +$18,585.12 | <0.01 | |
Bridgeway Capital Management | $556,485.00 | 0.28 | 161,300 | -13.42% | -$86,250.00 | 0.01 | |
Susquehanna Fundamental Investments Llc | $538,052.00 | 0.27 | 155,957 | New | +$538,052.00 | 0.03 | |
Ameriprise Financial | $412,089.00 | 0.21 | 119,446 | +2.34% | +$9,418.51 | <0.0001 | |
Ancora Advisors Llc | $408,942.00 | 0.21 | 118,534 | -27.29% | -$153,486.94 | 0.01 | |
Group One Trading | $383,840.00 | 0.19 | 111,258 | -51.81% | -$412,602.64 | 0.01 | |
Bank of America | $379,456.00 | 0.19 | 109,987 | -35.38% | -$207,773.27 | <0.0001 | |
RhumbLine Advisers | $363,420.00 | 0.18 | 105,343 | -3.43% | -$12,902.53 | <0.0001 | |
OZ MANAGEMENT LLC | $331,200.00 | 0.17 | 96,000 | New | +$331,200.00 | 0.01 | |
Badgley Phelps Wealth Managers Llc | $271,019.00 | 0.14 | 78,556 | 0% | +$0 | 0.01 | |
Barclays | $268,000.00 | 0.13 | 77,643 | -34.46% | -$140,912.02 | <0.0001 | |
Simplex Trading Llc | $250,000.00 | 0.13 | 72,477 | New | +$250,000.00 | 0.01 | |
American Financial Group | $221,000.00 | 0.11 | 64,113 | 0% | +$0 | 0.1 | |
Sheaff Brock Investment Advisors | $207,432.00 | 0.1 | 60,125 | 0% | +$0 | 0.02 | |
Hightower Advisors | $190,000.00 | 0.1 | 55,339 | -1.77% | -$3,433.38 | <0.0001 | |
Two Sigma | $189,467.00 | 0.1 | 54,918 | +15.37% | +$25,247.09 | <0.0001 | |
Nuveen | $190,599.00 | 0.1 | 55,246 | New | +$190,599.00 | <0.0001 | |
Susquehanna International Group | $185,189.00 | 0.09 | 53,678 | -52.79% | -$207,089.59 | <0.0001 | |
Goldman Sachs | $165,093.00 | 0.08 | 47,853 | +14.32% | +$20,686.22 | <0.0001 | |
Citadel Advisors LLC | $129,568.00 | 0.07 | 37,556 | -28.75% | -$52,291.57 | <0.0001 | |
Invesco | $126,508.00 | 0.06 | 36,669 | -13.5% | -$19,737.44 | <0.0001 | |
T. Rowe Price | $122,000.00 | 0.06 | 35,181 | +6.83% | +$7,795.57 | <0.0001 | |
Two Sigma Advisers LP | $121,440.00 | 0.06 | 35,200 | +66.83% | +$48,645.00 | <0.0001 | |
Brighton Jones | $115,631.00 | 0.06 | 33,516 | 0% | +$0 | 0.01 | |
Comerica | $103,500.00 | 0.05 | 30,000 | +20% | +$17,250.00 | <0.0001 | |
American International Group | $103,507.00 | 0.05 | 30,002 | -0.85% | -$890.10 | <0.0001 | |
Empirical Financial Services Llc D B A Empirical Wealth Management | $103,500.00 | 0.05 | 30,000 | 0% | +$0 | <0.01 | |
Deutsche Bank | $97,863.00 | 0.05 | 28,366 | -3.71% | -$3,774.31 | <0.0001 | |
Coldstream Wealth Management | $96,014.00 | 0.05 | 27,830 | -1.07% | -$1,035.01 | <0.01 | |
JPMorgan Chase | $91,867.00 | 0.05 | 26,628 | -35.55% | -$50,670.37 | <0.0001 | |
Millennium Management LLC | $91,825.00 | 0.05 | 26,616 | +150.62% | +$55,186.08 | <0.0001 | |
Cypress Capital Group | $86,250.00 | 0.04 | 25,000 | -54.55% | -$103,500.00 | 0.01 | |
The Manufacturers Life Insurance Company | $86,726.00 | 0.04 | 25,138 | 0% | +$0 | <0.0001 |