Omega Therapeutics, Inc. operates as a development-stage biopharmaceutical company. Its OMEGA Epigenomic Programming platform is designed to coopt nature's operating system by harnessing the power of epigenetics, the mechanism for gene control and cell differentiation. The company is developing omega epigenomic controller (OEC) candidates to up-regulate the expression of HNF4a, a transcriptional master regulator as a potential way to restore liver-cell function in patients suffering from chronic liver diseases; to control the expression of genes that have been strongly linked to cell-growth inhibition in patients with diabetes and other conditions to restore the capacity for corneal regeneration; to down-regulate expression of the CXCL1, 2, 3, and IL-8 gene cluster; to control expression of genes implicated in patients with idiopathic pulmonary fibrosis to halt or reverse disease progression and improve disease outcomes; to down-regulate the expression of SFRP1, a protein that inhibits hair growth; and to treat non-small cell lung cancer and small cell lung cancer. It is also developing OTX-2002 to down-regulate c-Myc, an oncogene. The company was incorporated in 2016 and is headquartered in Cambridge, Massachusetts.
Over the last 12 months, insiders at Omega Therapeutics, Inc. have bought $0 and sold $0 worth of Omega Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Omega Therapeutics, Inc. have bought $28.12M and sold $440,000 worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 3,323,310 shares for transaction amount of $19.21M was made by Flagship Pioneering Inc. (10 percent owner) on 2023‑02‑27.
2023-06-02 | Sale | Young Richard A | director | 5,000 0.0098% | $8.00 | $40,000 | -59.06% | |
2023-05-01 | Sale | Young Richard A | director | 5,000 0.0097% | $8.00 | $40,000 | -56.17% | |
2023-04-06 | Sale | Young Richard A | director | 5,000 0.0102% | $8.00 | $40,000 | -52.52% | |
2023-03-17 | Sale | Young Richard A | director | 10,000 0.0162% | $8.00 | $80,000 | -60.53% | |
2023-02-27 | Flagship Pioneering Inc. | 10 percent owner | 3.32M 6.508% | $5.78 | $19.21M | -31.56% | ||
2023-01-10 | Sale | Young Richard A | director | 20,000 0.0383% | $8.00 | $160,000 | -36.67% | |
2022-09-14 | Sale | Young Richard A | director | 10,000 0.0251% | $8.00 | $80,000 | -7.14% | |
2021-08-03 | Flagship Pioneering Inc. | 10 percent owner | 1.18M 3.7637% | $17.00 | $20M | -32.01% | ||
2021-08-03 | Invus Public Equities, L.P. | 10 percent owner | 875,000 2.7992% | $17.00 | $14.88M | -32.01% | ||
2021-08-03 | BERRY DAVID A | director | 53,082 0.1698% | $17.00 | $902,394 | -32.01% | ||
2021-08-03 | Sawhney Roger | Chief Financial Officer | 2,941 0.0094% | $17.00 | $49,997 | -32.01% | ||
2021-07-30 | Invus Public Equities, L.P. | 10 percent owner | 75,000 0.2342% | $16.14 | $1.21M | -29.19% |
Flagship Pioneering Inc. | 10 percent owner | 7508693 13.6171% | $2.35 | 2 | 0 | <0.0001% |
Invus Public Equities, L.P. | 10 percent owner | 2273530 4.1231% | $2.35 | 2 | 0 | <0.0001% |
Young Richard A | director | 739118 1.3404% | $2.35 | 0 | 6 | |
BERRY DAVID A | director | 53082 0.0963% | $2.35 | 1 | 0 | <0.0001% |
Sawhney Roger | Chief Financial Officer | 2941 0.0053% | $2.35 | 1 | 0 | <0.0001% |
Flagship Pioneering | $106.67M | 52.99 | 29.23M | 0% | +$0 | 7 | |
Fidelity Investments | $22.97M | 11.41 | 6.29M | +19.04% | +$3.67M | <0.01 | |
HarbourVest Partners | $12.82M | 6.37 | 3.51M | 0% | +$0 | 5.86 | |
State of Wisconsin Investment Board | $6.78M | 3.37 | 1.86M | 0% | +$0 | 0.02 | |
BlackRock | $5.17M | 2.57 | 1.42M | +2.4% | +$120,990.22 | <0.0001 | |
Artal Group S A | $4.83M | 2.4 | 1.32M | 0% | +$0 | 0.03 | |
The Vanguard Group | $4.67M | 2.32 | 1.28M | -15.19% | -$836,809.91 | <0.0001 | |
Blue Owl Capital Holdings Lp | $3.85M | 1.91 | 1.06M | 0% | +$0 | 0.73 | |
PLATINUM INVESTMENT MANAGEMENT LTD | $3.24M | 1.61 | 886,782 | 0% | +$0 | 0.04 | |
Geode Capital Management | $1.83M | 0.91 | 500,504 | +4.79% | +$83,469.92 | <0.0001 | |
State Street | $1.76M | 0.87 | 481,577 | +6.68% | +$110,025.60 | <0.0001 | |
Citigroup | $1.75M | 0.87 | 479,069 | +0.08% | +$1,335.90 | <0.01 | |
72 Investment Holdings Llc | $1.29M | 0.64 | 352,941 | 0% | +$0 | 1.92 | |
Millennium Management LLC | $1.19M | 0.59 | 327,145 | +1,137.68% | +$1.1M | <0.01 | |
State Of Michigan Retirement System | $1.15M | 0.57 | 314,117 | 0% | +$0 | 0.01 | |
Jacobs Levy Equity Management | $1.02M | 0.51 | 279,464 | -6.31% | -$68,682.08 | 0.01 | |
Northern Trust | $729,054.00 | 0.36 | 199,741 | +1.21% | +$8,727.14 | <0.0001 | |
Bridgeway Capital Management | $525,600.00 | 0.26 | 144,000 | New | +$525,600.00 | 0.01 | |
Point72 Asset Management | $472,270.00 | 0.24 | 129,389 | 0% | +$0 | <0.01 | |
Morgan Stanley | $469,255.00 | 0.23 | 128,563 | +41.48% | +$137,590.42 | <0.0001 | |
BNY Mellon | $458,245.00 | 0.23 | 125,546 | -3.76% | -$17,881.43 | <0.0001 | |
683 Capital Management Llc | $419,750.00 | 0.21 | 115,000 | 0% | +$0 | 0.05 | |
RBF Capital, LLC | $241,838.00 | 0.12 | 66,257 | 0% | +$0 | 0.01 | |
Charles Schwab | $237,655.00 | 0.12 | 65,111 | 0% | +$0 | <0.0001 | |
Nuveen | $223,183.00 | 0.11 | 61,146 | +33.13% | +$55,534.78 | <0.0001 | |
Marshall Wace | $217,346.00 | 0.11 | 59,547 | New | +$217,346.00 | <0.0001 | |
Susquehanna International Group | $121,253.00 | 0.06 | 33,220 | -49.99% | -$121,220.15 | <0.0001 | |
Wells Fargo | $115,716.00 | 0.06 | 31,703 | +60.71% | +$43,712.42 | <0.0001 | |
Barclays | $111,000.00 | 0.06 | 30,473 | -35.13% | -$60,102.39 | <0.0001 | |
UBS | $101,142.00 | 0.05 | 27,710 | +0.36% | +$361.35 | <0.0001 | |
American Century Investments | $92,400.00 | 0.05 | 25,315 | +107.08% | +$47,778.63 | <0.0001 | |
Gsa Capital Partners Llp | $86,000.00 | 0.04 | 23,649 | New | +$86,000.00 | 0.01 | |
Citadel Advisors LLC | $85,775.00 | 0.04 | 23,500 | New | +$85,775.00 | <0.0001 | |
RhumbLine Advisers | $81,531.00 | 0.04 | 22,339 | +3.44% | +$2,711.74 | <0.0001 | |
Goldman Sachs | $80,548.00 | 0.04 | 22,068 | +70.04% | +$33,178.42 | <0.0001 | |
Bank of America | $79,045.00 | 0.04 | 21,656 | -63.27% | -$136,135.08 | <0.0001 | |
Cubist Systematic Strategies | $64,764.00 | 0.03 | 17,744 | New | +$64,764.00 | <0.01 | |
Murphy Pohlad Asset Management Llc | $60,225.00 | 0.03 | 16,500 | 0% | +$0 | 0.02 | |
Harbor Capital Advisors Inc | $61,000.00 | 0.03 | 16,775 | New | +$61,000.00 | 0.01 | |
SEI Investments Company | $55,535.00 | 0.03 | 15,215 | New | +$55,535.00 | <0.0001 | |
New York State Common Retirement Fund | $51,000.00 | 0.03 | 14,082 | -0.2% | -$101.41 | <0.0001 | |
American International Group | $43,840.00 | 0.02 | 12,011 | -0.85% | -$375.95 | <0.0001 | |
Dimensional Fund Advisors | $44,567.00 | 0.02 | 12,210 | New | +$44,567.00 | <0.0001 | |
Deutsche Bank | $44,556.00 | 0.02 | 12,207 | +693.69% | +$38,942.24 | <0.0001 | |
Ameriprise Financial | $39,238.00 | 0.02 | 10,750 | New | +$39,238.00 | <0.0001 | |
The Manufacturers Life Insurance Company | $38,435.00 | 0.02 | 10,530 | New | +$38,435.00 | <0.0001 | |
Invesco | $39,084.00 | 0.02 | 10,708 | -1.03% | -$405.15 | <0.0001 | |
JPMorgan Chase | $36,858.00 | 0.02 | 10,098 | -36.08% | -$20,801.52 | <0.0001 | |
Group One Trading | $18,458.00 | 0.01 | 5,057 | +261.21% | +$13,348.01 | <0.01 | |
Tower Research Capital | $18,743.00 | 0.01 | 5,135 | +26.82% | +$3,963.95 | <0.0001 |