Pyxis Oncology, Inc., a preclinical stage biopharmaceutical company, engages in the development of therapies to treat cancers. Its immune-oncology product candidates include PYX-106, an investigational fully human immunoglobulin G1 isotype siglec-15 targeting antibody for the treatment of thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors; and PYX-102, an investigational immune-therapeutic for treatment of solid tumors. The company's antibody drug conjugate (ADC) product candidates comprise of PYX-201, an investigational novel ADC to treat NSCLC, breast cancer, and other solid tumors; PYX-202, an investigational novel ADC for treatment of SCLC, soft tissue sarcoma, and other solid tumors; and PYX-203, an investigational ADC for the treatment of acute myeloid leukemia and myeloid dysplastic syndrome. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.
Over the last 12 months, insiders at Pyxis Oncology, Inc. have bought $73,440 and sold $81,462 worth of Pyxis Oncology, Inc. stock.
On average, over the past 5 years, insiders at Pyxis Oncology, Inc. have bought $5.86M and sold $2.7M worth of stock each year.
Highest buying activity among insiders over the last 12 months: Connealy Pamela Ann (CFO and COO) — $55,566. Wadhane Jitendra (Chief Accounting Officer) — $17,874.
The last purchase of 8,000 shares for transaction amount of $14,960 was made by Connealy Pamela Ann (CFO and COO) on 2023‑09‑28.
2023-09-28 | Connealy Pamela Ann | CFO and COO | 8,000 0.0167% | $1.87 | $14,960 | +80.39% | ||
2023-09-27 | Connealy Pamela Ann | CFO and COO | 6,426 0.0147% | $1.85 | $11,868 | +99.46% | ||
2023-09-27 | Wadhane Jitendra | Chief Accounting Officer | 2,500 0.0058% | $1.87 | $4,675 | +99.46% | ||
2023-09-25 | Connealy Pamela Ann | CFO and COO | 12,000 0.0257% | $1.67 | $20,044 | +105.62% | ||
2023-09-25 | Wadhane Jitendra | Chief Accounting Officer | 5,000 0.0113% | $1.77 | $8,850 | +105.62% | ||
2023-09-22 | Connealy Pamela Ann | CFO and COO | 5,000 0.0124% | $1.74 | $8,695 | +128.75% | ||
2023-09-22 | Wadhane Jitendra | Chief Accounting Officer | 2,500 0.0062% | $1.74 | $4,349 | +128.75% | ||
2023-09-18 | Sale | Sullivan Lara | President and CEO | 8,541 0.02% | $2.10 | $17,936 | +77.94% | |
2023-09-14 | Sale | Sullivan Lara | President and CEO | 100 0.0002% | $2.25 | $225 | +63.76% | |
2023-09-13 | Sale | Sullivan Lara | President and CEO | 3,000 0.007% | $2.27 | $6,816 | +58.71% | |
2023-09-12 | Sale | Sullivan Lara | President and CEO | 4,917 0.0114% | $2.25 | $11,071 | +59.46% | |
2023-09-11 | Sale | Sullivan Lara | President and CEO | 20,000 0.045% | $2.27 | $45,414 | +51.30% | |
2023-03-17 | PFIZER INC | 10 percent owner | 1.81M 5.1245% | $2.76 | $5M | -10.51% | ||
2022-04-21 | Sale | Chin Mark | 1.75M 6.1916% | $3.05 | $5.32M | -16.98% | ||
2021-12-08 | Cline Darren S | director | 10,000 0.0316% | $9.39 | $93,885 | -71.08% | ||
2021-11-18 | Civik Thomas | director | 15,700 0.048% | $12.74 | $200,018 | -78.75% | ||
2021-10-13 | Chin Mark | director | 312,500 1.3218% | $16.00 | $5M | -70.72% | ||
2021-10-13 | Cormorant Asset Management, LP | 450,000 1.9034% | $16.00 | $7.2M | -70.72% |
Sullivan Lara | President and CEO | 2403882 5.4271% | $3.21 | 0 | 5 | |
Connealy Pamela Ann | CFO and COO | 818532 1.8479% | $3.21 | 4 | 0 | |
Wadhane Jitendra | Chief Accounting Officer | 226937 0.5123% | $3.21 | 3 | 0 | |
PFIZER INC | 10 percent owner | 5952263 13.4381% | $3.21 | 1 | 0 | <0.0001% |
Cormorant Asset Management, LP | 1118854 2.526% | $3.21 | 1 | 0 | <0.0001% | |
Civik Thomas | director | 15700 0.0354% | $3.21 | 1 | 0 | <0.0001% |
Cline Darren S | director | 10000 0.0226% | $3.21 | 1 | 0 | <0.0001% |
Chin Mark | 0 0% | $3.21 | 1 | 1 | <0.0001% |
Deep Track Capital Lp | $17.82M | 7.11 | 4.18M | New | +$17.82M | 0.08 | |
Laurion Capital Management LP | $16.45M | 6.56 | 3.86M | +21.77% | +$2.94M | 0.46 | |
Balyasny Asset Management Llc | $11.05M | 4.41 | 2.59M | New | +$11.05M | 0.03 | |
Ikarian Capital LLC | $7.08M | 2.82 | 1.66M | New | +$7.08M | 2.02 | |
The Vanguard Group | $5.97M | 2.38 | 1.4M | +7.25% | +$403,592.37 | <0.0001 | |
Standard Life | $3.02M | 1.2 | 708,303 | 0% | +$0 | 0.01 | |
Millennium Management LLC | $2.48M | 0.99 | 583,009 | +4,292.77% | +$2.43M | <0.01 | |
Boothbay Fund Management LLC | $2.1M | 0.84 | 492,462 | New | +$2.1M | 0.07 | |
Monashee Investment Management LLC | $1.89M | 0.75 | 442,500 | New | +$1.89M | 0.16 | |
Hillhouse Capital Advisors Ltd | $1.63M | 0.65 | 382,606 | 0% | +$0 | 0.04 | |
Geode Capital Management | $1.45M | 0.58 | 340,121 | +10.34% | +$135,840.34 | <0.0001 | |
Goldman Sachs | $1.43M | 0.57 | 336,691 | New | +$1.43M | <0.0001 | |
BlackRock | $1.37M | 0.55 | 321,665 | +3.56% | +$47,145.46 | <0.0001 | |
Bridgeway Capital Management | $986,169.00 | 0.39 | 231,495 | -1.99% | -$20,022.01 | 0.02 | |
Jane Street Capital | $746,573.00 | 0.3 | 175,252 | +1,067.1% | +$682,604.88 | <0.01 | |
Deutsche Bank | $702,900.00 | 0.28 | 165,000 | +32% | +$170,400.00 | <0.0001 | |
BNY Mellon | $690,580.00 | 0.28 | 162,108 | +904.76% | +$621,849.17 | <0.0001 | |
Qube Research & Technologies | $651,806.00 | 0.26 | 153,006 | New | +$651,797.48 | <0.01 | |
Renaissance Technologies | $630,000.00 | 0.25 | 148,000 | -59.36% | -$920,097.97 | <0.01 | |
Man Group Plc | $626,987.00 | 0.25 | 147,180 | New | +$626,987.00 | <0.01 | |
Hrt Financial Llc | $592,000.00 | 0.24 | 139,142 | New | +$592,000.00 | <0.01 | |
Marshall Wace | $569,033.00 | 0.23 | 133,576 | New | +$569,033.00 | <0.01 | |
State Street | $465,852.00 | 0.19 | 109,355 | +31.67% | +$112,037.93 | <0.0001 | |
Dimensional Fund Advisors | $433,711.00 | 0.17 | 101,810 | 0% | +$0 | <0.0001 | |
ExodusPoint Capital Management, LP | $381,000.00 | 0.15 | 89,471 | New | +$381,000.00 | 0.01 | |
Susquehanna Fundamental Investments Llc | $351,224.00 | 0.14 | 82,447 | New | +$351,224.00 | 0.02 | |
Cornercap Investment Counsel Inc | $319,087.00 | 0.13 | 74,903 | 0% | +$0 | 0.05 | |
Susquehanna International Group | $295,861.00 | 0.12 | 69,451 | +487.42% | +$245,495.06 | <0.0001 | |
Squarepoint Ops LLC | $291,205.00 | 0.12 | 68,358 | New | +$291,205.00 | <0.01 | |
Xtx Topco Ltd | $280,572.00 | 0.11 | 65,862 | +220.36% | +$192,990.70 | 0.02 | |
Northern Trust | $260,857.00 | 0.1 | 61,234 | +1.58% | +$4,051.26 | <0.0001 | |
Marathon Trading Investment Management Llc | $242,820.00 | 0.1 | 57,000 | New | +$242,820.00 | 0.1 | |
Pier 88 Investment Partners LLC | $218,794.00 | 0.09 | 51,360 | New | +$218,794.00 | 0.35 | |
University Of Chicago | $207,594.00 | 0.08 | 48,731 | New | +$207,594.00 | 0.3 | |
Citigroup | $190,401.00 | 0.08 | 44,695 | New | +$190,401.00 | <0.0001 | |
Morgan Stanley | $185,425.00 | 0.07 | 43,527 | +1,260.22% | +$171,793.00 | <0.0001 | |
Jump Financial Llc | $172,326.00 | 0.07 | 40,452 | New | +$172,326.00 | <0.01 | |
American Century Investments | $159,115.00 | 0.06 | 37,351 | +171.23% | +$100,450.64 | <0.0001 | |
Brevan Howard Capital Management Lp | $153,305.00 | 0.06 | 35,987 | New | +$153,305.00 | 0.01 | |
Point72 Asia Singapore Pte Ltd | $127,097.00 | 0.05 | 29,835 | New | +$127,097.00 | 0.01 | |
Bank of America | $126,577.00 | 0.05 | 29,713 | +49.73% | +$42,041.81 | <0.0001 | |
Y Intercept Hong Kong Ltd | $119,506.00 | 0.05 | 28,053 | New | +$119,506.00 | 0.01 | |
UBS | $120,345.00 | 0.05 | 28,250 | +856.01% | +$107,756.70 | <0.0001 | |
Royal Bank of Canada | $109,000.00 | 0.04 | 25,600 | +2,586.25% | +$104,942.30 | <0.0001 | |
Cetera Advisors LLC | $100,110.00 | 0.04 | 23,500 | New | +$100,110.00 | <0.01 | |
Schulhoff Co Inc | $93,720.00 | 0.04 | 22,000 | 0% | +$0 | 0.04 | |
Two Sigma Advisers LP | $66,456.00 | 0.03 | 15,600 | -75.7% | -$207,036.00 | <0.0001 | |
Charles Schwab | $61,872.00 | 0.03 | 14,524 | New | +$61,872.00 | <0.0001 | |
SG Americas Securities, LLC | $59,000.00 | 0.02 | 13,809 | New | +$59,000.00 | <0.0001 | |
OMERS | $50,268.00 | 0.02 | 11,800 | New | +$50,268.00 | <0.01 |