Soleno Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead candidate is Diazoxide Choline Controlled-Release, a once-daily oral tablet for the treatment of Prader-Willi Syndrome, which is being evaluated in an ongoing Phase III clinical development program. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics, Inc. was incorporated in 1999 and is based in Redwood City, California.
Over the last 12 months, insiders at Soleno Therapeutics, Inc. have bought $25.02M and sold $62.47M worth of Soleno Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Soleno Therapeutics, Inc. have bought $15.69M and sold $13.83M worth of stock each year.
Highest buying activity among insiders over the last 12 months: PERCEPTIVE ADVISORS LLC (10 percent owner) — $425.32M.
The last purchase of 250,000 shares for transaction amount of $5M was made by PERCEPTIVE ADVISORS LLC (10 percent owner) on 2023‑09‑28.
2024-04-30 | Sale | Vivo Opportunity, LLC | 10 percent owner | 351,242 1.0623% | $45.13 | $15.85M | -0.57% | |
2024-04-29 | Sale | Vivo Opportunity, LLC | 10 percent owner | 750,000 2.3567% | $47.80 | $35.85M | -2.17% | |
2024-04-01 | Sale | Anish Bhatnagar | CHIEF EXECUTIVE OFFICER | 18,980 0.0583% | $41.34 | $784,645 | +2.22% | |
2024-04-01 | Sale | Mackaness James H | CHIEF FINANCIAL OFFICER | 5,175 0.0159% | $41.34 | $213,937 | +2.22% | |
2024-04-01 | Sale | Hirano Patricia C | SEE REMARKS | 2,218 0.0068% | $41.34 | $91,694 | +2.22% | |
2024-04-01 | Sale | Yen Kristen | SEE REMARKS | 2,218 0.0068% | $41.34 | $91,694 | +2.22% | |
2024-01-25 | Sale | Anish Bhatnagar | CHIEF EXECUTIVE OFFICER | 2,527 0.0086% | $48.30 | $122,054 | -4.64% | |
2024-01-25 | Sale | Hirano Patricia C | SEE REMARKS | 832 0.0028% | $48.30 | $40,186 | -4.64% | |
2024-01-25 | Sale | Yen Kristen | SEE REMARKS | 397 0.0014% | $48.30 | $19,175 | -4.64% | |
2023-12-14 | Sale | Hirano Patricia C | See Remarks | 1,359 0.0044% | $36.49 | $49,584 | +16.49% | |
2023-12-13 | Sale | Hirano Patricia C | See Remarks | 4,885 0.016% | $38.79 | $189,513 | +12.56% | |
2023-12-13 | Sale | Yen Kristen | See Remarks | 17,916 0.0572% | $37.76 | $676,557 | +12.56% | |
2023-12-12 | Sale | Yen Kristen | See Remarks | 19,913 0.0649% | $36.95 | $735,874 | +17.06% | |
2023-12-11 | Sale | Anish Bhatnagar | Chief Executive Officer | 93,408 0.311% | $35.67 | $3.33M | +23.21% | |
2023-12-11 | Sale | Mackaness James H | Chief Financial Officer | 32,482 0.1104% | $36.41 | $1.18M | +23.21% | |
2023-11-30 | Sale | Anish Bhatnagar | Chief Executive Officer | 27,716 0.0882% | $28.65 | $794,116 | +45.58% | |
2023-11-30 | Sale | Hirano Patricia C | See Remarks | 3,823 0.0122% | $28.65 | $109,536 | +45.58% | |
2023-11-30 | Sale | Yen Kristen | See Remarks | 3,963 0.0126% | $28.65 | $113,547 | +45.58% | |
2023-11-30 | Sale | Mackaness James H | Chief Financial Officer | 4,186 0.0133% | $28.65 | $119,937 | +45.58% | |
2023-11-29 | Sale | Anish Bhatnagar | Chief Executive Officer | 27,827 0.0897% | $27.83 | $774,535 | +51.19% |
Vivo Opportunity, LLC | 10 percent owner | 7316851 21.8993% | $39.56 | 0 | 2 | |
PERCEPTIVE ADVISORS LLC | 10 percent owner | 3074542 10.0807% | $39.56 | 15 | 0 | +439.37% |
Anish Bhatnagar | CHIEF EXECUTIVE OFFICER | 152790 0.5632% | $39.56 | 4 | 7 | <0.0001% |
Hirano Patricia C | SEE REMARKS | 41812 0.1415% | $39.56 | 0 | 7 | |
Yen Kristen | SEE REMARKS | 23422 0.0841% | $39.56 | 0 | 7 | |
Mackaness James H | Chief Financial Officer | 62953 0.0398% | $39.56 | 3 | 5 | <0.0001% |
Abingworth LLP | 10 percent owner | 18022602 59.0917% | $39.56 | 3 | 0 | +8.21% |
Sinclair Andrew | 18022602 59.0917% | $39.56 | 4 | 0 | +23.93% | |
ENGLEMAN EDGAR | 4033540 13.225% | $39.56 | 2 | 0 | +22.67% | |
Vivo Ventures V, LLC | 10 percent owner | 3633805 11.9143% | $39.56 | 2 | 18 | +22.67% |
MARIO ERNEST | 930000 3.0492% | $39.56 | 10 | 0 | <0.0001% | |
FEINBERG LARRY N | 10 percent owner | 655000 2.1476% | $39.56 | 5 | 2 | +13.73% |
ENGELSEN STEINAR J | director | 80960 0.2654% | $39.56 | 3 | 0 | |
Harris William G | director | 66271 0.2173% | $39.56 | 0 | 1 | |
O'Toole David D | See Remarks | 44750 0.1467% | $39.56 | 7 | 0 | <0.0001% |
TP MANAGEMENT VII LLC | 10 percent owner | 36823 0.1207% | $39.56 | 1 | 3 | |
SCHULER JACK W | 10 percent owner | 36595 0.12% | $39.56 | 34 | 79 | +2.37% |
Melincoff Gwen A | director | 10000 0.0328% | $39.56 | 1 | 0 | +35.53% |
BIOASIA MANGEMENT LLC | 10 percent owner | 0 0% | $39.56 | 0 | 2 |
Vivo Capital | $360.29M | 24.28 | 8.42M | 0% | +$0 | 31.74 | |
The Carlyle Group | $173.12M | 11.74 | 4.07M | +42.47% | +$51.61M | 7.5 | |
Perceptive Advisors | $131.59M | 8.87 | 3.07M | 0% | +$0 | 0.09 | |
Janus Henderson | $122.7M | 8.28 | 2.87M | +13.74% | +$14.83M | 0.07 | |
Nantahala Capital Management Llc | $103.16M | 6.95 | 2.41M | -15.61% | -$19.09M | 10.58 | |
Adage Capital Partners Gp L L C | $83.18M | 5.6 | 1.94M | +6.39% | +$5M | 0.15 | |
Avoro Capital Advisors Llc | $69.55M | 4.69 | 1.63M | +107.01% | +$35.95M | 0.83 | |
State Street | $41.54M | 2.8 | 970,570 | +93.57% | +$20.08M | <0.01 | |
The Vanguard Group | $41.5M | 2.8 | 969,655 | +<0.01% | +$1,412.40 | <0.01 | |
Frazier Life Sciences Management L P | $37.48M | 2.53 | 875,667 | +88.34% | +$17.58M | 1.92 | |
Ikarian Capital LLC | $24.2M | 1.63 | 565,411 | -4.21% | -$1.06M | 6.9 | |
Tcg Crossover Management Llc | $23.54M | 1.59 | 550,000 | New | +$23.54M | 0.04 | |
Wellington Management Company | $15.13M | 1.02 | 353,481 | +66.26% | +$6.03M | <0.01 | |
Ally Bridge Group | $14.4M | 0.97 | 336,486 | +8.56% | +$1.14M | 8.1 | |
BlackRock | $13.97M | 0.94 | 326,298 | +4.03% | +$540,863.62 | <0.0001 | |
Invesco | $13.7M | 0.92 | 320,030 | New | +$13.7M | <0.01 | |
Emerald Advisers, Inc. | $12.86M | 0.87 | 300,376 | +19.12% | +$2.06M | 0.52 | |
EMERALD MUTUAL FUND ADVISERS TRUST | $9.92M | 0.67 | 231,761 | +15.12% | +$1.3M | 0.52 | |
Samlyn Capital, LLC | $9.37M | 0.63 | 218,927 | -27.45% | -$3.55M | 0.16 | |
Goldman Sachs | $9.07M | 0.61 | 211,917 | +208.92% | +$6.13M | <0.01 | |
GHOST TREE CAPITAL LLC | $8.56M | 0.58 | 200,000 | +77.96% | +$3.75M | 2.78 | |
Marshall Wace | $7.54M | 0.51 | 176,237 | New | +$7.54M | 0.01 | |
Commodore Capital, LP | $7.26M | 0.49 | 169,533 | -75.78% | -$22.7M | 0.51 | |
Geode Capital Management | $7.15M | 0.48 | 167,021 | +2.56% | +$178,822.65 | <0.01 | |
Altium Capital Management Lp | $6.54M | 0.44 | 152,909 | +45.75% | +$2.05M | 3.04 | |
T. Rowe Price | $6.53M | 0.44 | 152,620 | New | +$6.53M | <0.01 | |
Balyasny Asset Management Llc | $6.49M | 0.44 | 151,618 | -83.64% | -$33.18M | 0.02 | |
Sofinnova | $6.45M | 0.44 | 150,775 | +12,464.58% | +$6.4M | 0.01 | |
Boothbay Fund Management LLC | $5.65M | 0.38 | 132,031 | +7.22% | +$380,577.61 | 0.19 | |
Woodline Partners LP | $4.56M | 0.31 | 106,460 | -46.77% | -$4M | 0.04 | |
Rafferty Asset Management Llc | $4.54M | 0.31 | 106,144 | +104.62% | +$2.32M | 0.01 | |
Morgan Stanley | $4.45M | 0.3 | 104,003 | +105.19% | +$2.28M | <0.0001 | |
Allspring Global Investments | $4.44M | 0.3 | 103,839 | New | +$4.44M | 0.01 | |
Soros Fund Management | $4.28M | 0.29 | 100,000 | New | +$4.28M | 0.18 | |
Citigroup | $4.18M | 0.28 | 97,754 | +187.83% | +$2.73M | <0.01 | |
Millennium Management LLC | $3.95M | 0.27 | 92,225 | +574.01% | +$3.36M | <0.01 | |
Qube Research & Technologies | $3.36M | 0.23 | 78,500 | +319.88% | +$2.56M | <0.01 | |
683 Capital Management Llc | $3.34M | 0.23 | 78,000 | -10.35% | -$385,200.00 | 0.38 | |
Bank of America | $3.12M | 0.21 | 72,826 | +26.72% | +$657,236.84 | <0.0001 | |
Eam Investors | $2.76M | 0.19 | 64,411 | -31.06% | -$1.24M | 0.43 | |
UBS | $2.3M | 0.16 | 53,805 | +202.48% | +$1.54M | <0.01 | |
Schonfeld Group | $1.95M | 0.13 | 45,472 | -25.32% | -$659,889.86 | 0.01 | |
Artia Global Partners Lp | $1.75M | 0.12 | 40,924 | New | +$1.75M | 0.43 | |
Caption Management Llc | $1.71M | 0.12 | 40,000 | New | +$1.71M | 0.05 | |
Jefferies Financial Group | $1.54M | 0.1 | 35,891 | +2.28% | +$34,240.00 | 0.03 | |
Northern Trust | $1.45M | 0.1 | 33,968 | +1.95% | +$27,820.01 | <0.0001 | |
Ameriprise Financial | $1.33M | 0.09 | 31,140 | New | +$1.33M | <0.0001 | |
Swiss National Bank | $1.29M | 0.09 | 30,100 | +32.02% | +$312,440.00 | <0.01 | |
Farallon Capital | $1.19M | 0.08 | 27,750 | -83.2% | -$5.88M | 0.01 | |
Allianz Asset Management Gmbh | $1.07M | 0.07 | 25,100 | New | +$1.07M | <0.01 |