Xenon Pharmaceuticals Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics to treat patients with neurological disorders in Canada. Its clinical development pipeline includes XEN496, A Kv7 potassium channel opener that is Phase III clinical trials for the treatment of KCNQ2 developmental and epilepsy encephalopathy; and XEN1101, A Kv7 potassium channel opener, which is in Phase II clinical trial for the treatment of epilepsy and other neurological disorders. The company's product candidates also comprise NBI-921352, a selective Nav1.6 sodium channel inhibitor that is in Phase II clinical trials for the treatment of SCN8A developmental and epileptic encephalopathy, and other potential indications, including adult focal epilepsy; and XEN007, A central nervous system-acting calcium channel modulator, which is in Phase II clinical trials. It has a license and collaboration agreement with the Neurocrine Biosciences, Inc. to develop treatments for epilepsy; and with Flexion Therapeutics, Inc. to develop PCRX301 (XEN402, a Nav1.7 inhibitor) for the treatment of post-operative pain. Xenon Pharmaceuticals Inc. was incorporated in 1996 and is headquartered in Burnaby, Canada.
Over the last 12 months, insiders at Xenon Pharmaceuticals Inc. have bought $0 and sold $3.07M worth of Xenon Pharmaceuticals Inc. stock.
On average, over the past 5 years, insiders at Xenon Pharmaceuticals Inc. have bought $235,534 and sold $4.04M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 1,400 shares for transaction amount of $40,334 was made by KENNEY CHRISTOPHER JOHN (Chief Medical Officer) on 2022‑01‑21.
2024-03-08 | Sale | GAROFALO ELIZABETH A. | director | 2,092 0.0027% | $45.69 | $95,583 | -12.06% | |
2024-03-07 | Sale | ROBIN SHERRINGTON | EVP, Strategy & Innovation | 7,137 0.0095% | $46.28 | $330,290 | -11.72% | |
2024-03-07 | Sale | GANNON STEVEN | director | 13,000 0.0173% | $46.28 | $601,615 | -11.72% | |
2023-12-14 | Sale | PATOU GARY | director | 7,598 0.0103% | $41.05 | $311,898 | +4.34% | |
2023-12-13 | Sale | PATOU GARY | director | 18,978 0.0257% | $39.99 | $758,983 | +7.89% | |
2023-08-24 | Sale | Svoronos Dawn | director | 25,000 0.0391% | $38.70 | $967,500 | +4.46% | |
2023-06-01 | Sale | PIMSTONE SIMON N. | director | 31,713 0.0485% | $38.82 | $1.23M | +2.68% | |
2023-05-31 | Sale | PIMSTONE SIMON N. | director | 62,526 0.0956% | $38.70 | $2.42M | +2.88% | |
2023-05-30 | Sale | PIMSTONE SIMON N. | director | 37,006 0.0576% | $39.28 | $1.45M | +3.31% | |
2023-05-24 | Sale | MORTIMER IAN | PRESIDENT & CEO | 31,655 0.0482% | $41.41 | $1.31M | -3.86% | |
2023-03-24 | Sale | KENNEY CHRISTOPHER JOHN | Chief Medical Officer | 700 0.0011% | $35.01 | $24,507 | +10.93% | |
2023-03-07 | Sale | PIMSTONE SIMON N. | director | 19,232 0.03% | $36.98 | $711,199 | +6.69% | |
2022-11-25 | Sale | PATOU GARY | director | 1,937 0.0032% | $34.79 | $67,390 | +8.16% | |
2022-09-02 | Sale | AULIN SHERRY | Chief Financial Officer | 15,355 0.0238% | $39.57 | $607,597 | -3.33% | |
2022-08-31 | Sale | ROBIN SHERRINGTON | EVP, Strategy & Innovation | 8,776 0.0134% | $38.80 | $340,509 | -2.80% | |
2022-08-12 | Sale | PIMSTONE SIMON N. | 32,058 0.0495% | $38.29 | $1.23M | -0.50% | ||
2022-08-12 | Sale | EMPFIELD JAMES R. | EVP, Drug Discovery | 21,875 0.0341% | $38.68 | $846,125 | -0.50% | |
2022-03-08 | Sale | PIMSTONE SIMON N. | director | 5,000 0.0092% | $30.80 | $154,000 | +17.14% | |
2022-03-07 | Sale | PIMSTONE SIMON N. | director | 31,086 0.0572% | $30.50 | $948,260 | +18.01% | |
2022-03-07 | Sale | EMPFIELD JAMES R. | EVP, Drug Discovery | 32,853 0.0606% | $30.54 | $1M | +18.01% |
Svoronos Dawn | director | 25000 0.0338% | $36.57 | 1 | 1 | +44.5% |
ROBIN SHERRINGTON | EVP, Strategy & Innovation | 8398 0.0227% | $36.57 | 0 | 4 | |
GANNON STEVEN | director | 2000 0.0203% | $36.57 | 1 | 1 | +31.48% |
PATOU GARY | director | 4902 0.0066% | $36.57 | 2 | 3 | +22.07% |
GAROFALO ELIZABETH A. | director | 0 0% | $36.57 | 0 | 1 | |
BVF PARTNERS L P/IL | 10 percent owner | 1674468 2.2661% | $36.57 | 10 | 0 | <0.0001% |
Hayden Michael R | director | 161187 0.2181% | $36.57 | 1 | 0 | +44.5% |
HOLLER FRANK A | director | 143653 0.1944% | $36.57 | 0 | 10 | |
AZAB MOHAMMAD | director | 57561 0.0779% | $36.57 | 5 | 1 | +72.32% |
MORTIMER IAN | PRESIDENT & CEO | 24213 0.0328% | $36.57 | 2 | 1 | +28.18% |
EMPFIELD JAMES R. | EVP, Drug Discovery | 10000 0.0135% | $36.57 | 1 | 3 | +48.47% |
SCHELLER RICHARD H | director | 7000 0.0095% | $36.57 | 1 | 0 | +28.18% |
GOLDBERG Y. PAUL | VP of Clinical Development | 6000 0.0081% | $36.57 | 0 | 3 | |
PIMSTONE SIMON N. | director | 6000 0.0081% | $36.57 | 1 | 12 | +28.18% |
Von Seggern Christopher | Chief Commercial Officer | 4000 0.0054% | $36.57 | 1 | 0 | +29.4% |
WINQUIST RAYMOND | Head, Translational Research | 1000 0.0014% | $36.57 | 1 | 0 | +25.42% |
AULIN SHERRY | Chief Financial Officer | 0 0% | $36.57 | 0 | 1 | |
KENNEY CHRISTOPHER JOHN | Chief Medical Officer | 0 0% | $36.57 | 1 | 1 | +29.65% |
Fidelity Investments | $284.21M | 8.75 | 6.6M | +16.72% | +$40.72M | 0.02 | |
Avoro Capital Advisors Llc | $243.95M | 7.51 | 5.67M | 0% | +$0 | 2.92 | |
Driehaus Capital Management LLC | $186.05M | 5.73 | 4.32M | -0.54% | -$1.01M | 1.86 | |
Wellington Management Company | $168.84M | 5.2 | 3.92M | -5.78% | -$10.36M | 0.03 | |
Capital World Investors | $115.44M | 3.55 | 2.68M | 0% | +$0 | 0.02 | |
Polar Capital | $112.45M | 3.46 | 2.61M | -14.82% | -$19.57M | 0.62 | |
Paradigm BioCapital Advisors LP | $106.97M | 3.29 | 2.48M | +16.8% | +$15.39M | 3.88 | |
Capital International Investors | $106.59M | 3.28 | 2.48M | +0.82% | +$868,576.80 | 0.02 | |
Commodore Capital, LP | $93.32M | 2.87 | 2.17M | 0% | +$0 | 6.58 | |
BlackRock | $91.35M | 2.81 | 2.12M | +2.65% | +$2.36M | <0.01 | |
Adage Capital Partners Gp L L C | $71.98M | 2.22 | 1.67M | +59.42% | +$26.83M | 0.13 | |
AllianceBernstein | $63.22M | 1.95 | 1.47M | -6.74% | -$4.57M | 0.02 | |
Marshall Wace | $62.44M | 1.92 | 1.45M | -5.12% | -$3.37M | 0.08 | |
T Rowe Price Investment Management Inc | $61.4M | 1.89 | 1.43M | +60.06% | +$23.04M | 0.04 | |
First Light Asset Management | $56.83M | 1.75 | 1.32M | -19.77% | -$14M | 4.49 | |
Braidwell Lp | $56.31M | 1.73 | 1.31M | -20.6% | -$14.61M | 3.17 | |
Citadel Advisors LLC | $55.41M | 1.71 | 1.29M | +1.6% | +$870,944.55 | 0.04 | |
ROCK SPRINGS CAPITAL MANAGEMENT, LP | $54.05M | 1.66 | 1.26M | 0% | +$0 | 1.38 | |
Invesco | $45.18M | 1.39 | 1.05M | +45.83% | +$14.2M | 0.01 | |
Baker Bros Advisors LP | $42.78M | 1.32 | 993,679 | 0% | +$0 | 0.54 | |
Janus Henderson | $40.55M | 1.25 | 941,569 | -2.54% | -$1.05M | 0.02 | |
Lord Abbett | $38.54M | 1.19 | 895,196 | +24.68% | +$7.63M | 0.13 | |
Perceptive Advisors | $38.41M | 1.18 | 892,208 | -18.95% | -$8.98M | 0.03 | |
Affinity Asset Advisors | $36.05M | 1.11 | 837,387 | +82.04% | +$16.25M | 6.4 | |
TimesSquare Capital Management LLC | $31.73M | 0.98 | 737,173 | -7.15% | -$2.44M | 0.46 | |
Federated Hermes | $31.64M | 0.97 | 734,900 | +112.03% | +$16.72M | 0.07 | |
Avidity Partners Management Lp | $30.57M | 0.94 | 710,000 | -12.99% | -$4.56M | 1.11 | |
Loomis, Sayles & Company | $29.55M | 0.91 | 686,510 | -3.08% | -$937,836.14 | 0.04 | |
Boxer Capital, LLC | $25.83M | 0.8 | 600,000 | 0% | +$0 | 1.29 | |
Fiera Capital | $24.82M | 0.76 | 576,542 | +4.25% | +$1.01M | 0.07 | |
JENNISON ASSOCIATES LLC | $24.28M | 0.75 | 563,952 | -0.43% | -$105,214.21 | 0.02 | |
Candriam S C A | $24.15M | 0.74 | 560,884 | +5.65% | +$1.29M | 0.16 | |
OrbiMed | $23.68M | 0.73 | 550,000 | 0% | +$0 | 0.48 | |
Franklin Templeton Investments | $23.35M | 0.72 | 542,289 | +84.56% | +$10.7M | 0.01 | |
Great Point Partners | $19.64M | 0.6 | 456,148 | -23.98% | -$6.19M | 3.29 | |
Dimensional Fund Advisors | $17.66M | 0.54 | 410,207 | +1.87% | +$324,553.94 | 0.01 | |
Samlyn Capital, LLC | $17.06M | 0.53 | 396,196 | -5.93% | -$1.07M | 0.3 | |
Morgan Stanley | $16.63M | 0.51 | 386,199 | +71.53% | +$6.93M | <0.01 | |
Altium Capital Management Lp | $14.98M | 0.46 | 348,000 | +19.78% | +$2.47M | 6.97 | |
Westfield Capital Management Co Lp | $14.95M | 0.46 | 347,351 | +46.26% | +$4.73M | 0.08 | |
The Vanguard Group | $14.45M | 0.45 | 335,635 | +3.75% | +$522,626.97 | <0.0001 | |
Ally Bridge Group | $13.32M | 0.41 | 309,369 | +27.86% | +$2.9M | 7.49 | |
Goldman Sachs | $12.91M | 0.4 | 299,774 | -20.34% | -$3.29M | <0.01 | |
Boone Capital Management Llc | $12.54M | 0.39 | 291,403 | +14.08% | +$1.55M | 2.54 | |
Point72 Asset Management | $11.88M | 0.37 | 275,859 | -68.48% | -$25.8M | 0.02 | |
Two Sigma | $11.82M | 0.36 | 274,626 | -19.23% | -$2.81M | 0.02 | |
DAFNA Capital Management, LLC | $11.78M | 0.36 | 273,739 | -1.08% | -$129,150.00 | 2.74 | |
Artal Group S A | $10.91M | 0.34 | 253,387 | New | +$10.91M | 0.06 | |
Granahan Investment Management | $10.51M | 0.32 | 244,080 | -19.33% | -$2.52M | 0.37 | |
State Street | $10.45M | 0.32 | 242,640 | +6.87% | +$671,580.00 | <0.0001 |