| 2023-05-17 | Sale | Prothena Corporation plc PRTA | President and CEO | 45,000 0.0831% | $73.70 | $3.32M | -50.97% | |
| 2022-09-28 | Sale | Prothena Corporation plc PRTA | President and CEO | 1,342 0.0027% | $55.32 | $74,244 | -1.49% | |
| 2022-08-17 | Sale | Prothena Corporation plc PRTA | President and CEO | 2,181 0.0047% | $32.03 | $69,855 | +80.7% | |
| 2022-08-10 | Sale | Prothena Corporation plc PRTA | President and CEO | 20,284 0.0437% | $32.16 | $652,291 | +78.65% | |
| 2022-08-04 | Sale | Prothena Corporation plc PRTA | President and CEO | 20,954 0.0445% | $32.18 | $674,316 | +74.8% | |
| 2022-07-27 | Sale | Prothena Corporation plc PRTA | President and CEO | 376 0.0008% | $32.00 | $12,032 | +75.43% | |
| 2017-09-28 | Sale | Prothena Corporation plc PRTA | President and CEO | 2,800 0.0076% | $70.00 | $196,000 | -50.66% | |
| 2017-03-01 | Sale | Prothena Corporation plc PRTA | President and CEO | 25,163 0.0709% | $60.77 | $1.53M | -9.73% | |
| 2017-02-28 | Sale | Prothena Corporation plc PRTA | President and CEO | 3,796 0.0109% | $60.00 | $227,760 | -7.06% | |
| 2016-11-09 | Sale | Prothena Corporation plc PRTA | President and CEO | 8,548 0.0245% | $55.32 | $472,905 | -1.54% | |
| 2016-10-21 | Sale | Prothena Corporation plc PRTA | President and CEO | 5,834 0.0172% | $55.15 | $321,745 | +0.68% | |
| 2016-10-20 | Sale | Prothena Corporation plc PRTA | President and CEO | 14,785 0.0429% | $55.08 | $814,358 | -0.73% | |
| 2015-12-09 | Sale | Prothena Corporation plc PRTA | CSO & Head of R&D | 30,000 0.1001% | $66.15 | $1.98M | -26.71% | |
| 2014-05-09 | Prothena Corporation plc PRTA | CSO & Head of R&D | 2,500 0.0115% | $19.54 | $48,850 | +13.42% |