Prothena Corporation plc (PRTA)
Largest Insider Buys in Sector
PRTA Stock Price History Chart
PRTA Stock Performance
About Prothena Corporation plc
Prothena Corporation plc, a late-stage clinical company, focuses on discovery and development of novel therapies for life-threatening diseases in the United States. The company is involved in developing Birtamimab, an investigational humanized antibody that is in Phase III clinical trial for the treatment of AL amyloidosis; Prasinezumab, a humanized monoclonal antibody, which is in Phase IIb clinical trial for the treatment of Parkinson's disease; PRX004 that completed Phase I clinical trial for the treatment of Transthyretin amyloidosis; and PRX005, which is in Phase I clinical trial for the treatment of Alzheimer's disease. Its discovery and preclinical programs include PRX012 for the treatment of Alzheimer's disease; and dual Aß-Tau vaccine for the treatment and prevention of Alzheimer's disease. Prothena Corporation plc has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target alpha-synuclein; and a collaboration agreement with Bristol-Myers Squibb to develop antibodies. The company was founded in 2012 and is based in Dublin, Ireland.
Insider Activity of Prothena Corporation plc
Over the last 12 months, insiders at Prothena Corporation plc have bought $0 and sold $6.14M worth of Prothena Corporation plc stock.
On average, over the past 5 years, insiders at Prothena Corporation plc have bought $54.55M and sold $25.48M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 1,062,736 shares for transaction amount of $30.84M was made by EcoR1 Capital, LLC () on 2022‑05‑05.
List of Insider Buy and Sell Transactions, Prothena Corporation plc
| 2024-01-24 | Sale | Walker Karin L | Chief Accounting Officer | 5,000 0.0096% | $34.00 | $170,000 | -29.40% | |
| 2023-12-20 | Sale | Walker Karin L | Chief Accounting Officer | 5,000 0.0094% | $37.19 | $185,952 | -32.41% | |
| 2023-11-30 | Sale | Walker Karin L | Chief Accounting Officer | 5,000 0.0097% | $34.00 | $170,000 | -19.51% | |
| 2023-10-25 | Sale | Walker Karin L | Chief Accounting Officer | 5,000 0.0097% | $41.04 | $205,191 | -30.59% | |
| 2023-10-11 | Sale | Smith Brandon S. | Chief Operating Officer | 4,000 0.0074% | $46.75 | $186,985 | -40.09% | |
| 2023-10-04 | Sale | Karp Carol D. | Chief Regulatory Officer | 5,000 0.0093% | $46.62 | $233,084 | -37.32% | |
| 2023-09-27 | Sale | Malecek Michael J | Chief Legal Officer | 5,000 0.0093% | $47.38 | $236,885 | -39.88% | |
| 2023-09-19 | Sale | Walker Karin L | Chief Accounting Officer | 5,000 0.0093% | $52.36 | $261,807 | -44.52% | |
| 2023-09-13 | Sale | Smith Brandon S. | Chief Operating Officer | 4,000 0.0075% | $55.49 | $221,963 | -45.55% | |
| 2023-09-13 | Sale | Garren Hideki | Chief Medical Officer | 2,000 0.0037% | $55.48 | $110,952 | -45.55% | |
| 2023-09-06 | Sale | Karp Carol D. | Chief Regulatory Officer | 5,000 0.0093% | $54.76 | $273,804 | -44.93% | |
| 2023-08-30 | Sale | Malecek Michael J | Chief Legal Officer | 5,000 0.0095% | $55.01 | $275,066 | -40.85% | |
| 2023-08-18 | Sale | Walker Karin L | Chief Accounting Officer | 5,000 0.0096% | $57.18 | $285,923 | -42.84% | |
| 2023-08-16 | Sale | Smith Brandon S. | Chief Operating Officer | 4,000 0.0075% | $58.71 | $234,844 | -45.12% | |
| 2023-08-16 | Sale | Garren Hideki | Chief Medical Officer | 2,000 0.0038% | $58.74 | $117,480 | -45.12% | |
| 2023-08-02 | Sale | Zago Wagner M. | Chief Scientific Officer | 4,000 0.0075% | $67.05 | $268,182 | -51.35% | |
| 2023-08-02 | Sale | Karp Carol D. | Chief Regulatory Officer | 5,000 0.0094% | $67.01 | $335,072 | -51.35% | |
| 2023-07-26 | Sale | Malecek Michael J | Chief Legal Officer | 5,000 0.0095% | $62.33 | $311,638 | -47.30% | |
| 2023-07-19 | Sale | Walker Karin L | Chief Accounting Officer | 5,000 0.0099% | $69.19 | $345,943 | -49.98% | |
| 2023-07-12 | Sale | Smith Brandon S. | Chief Operating Officer | 4,000 0.0076% | $67.51 | $270,026 | -50.49% |
Insider Historical Profitability
| Selkoe Dennis J. | director | 2845 0.0053% | $19.96 | 0 | 17 | |
| Garren Hideki | Chief Medical Officer | 0 0% | $19.96 | 0 | 11 | |
| Karp Carol D. | Chief Regulatory Officer | 0 0% | $19.96 | 0 | 8 | |
| Walker Karin L | Chief Accounting Officer | 0 0% | $19.96 | 0 | 28 | |
| Zago Wagner M. | Chief Scientific Officer | 0 0% | $19.96 | 0 | 7 | |
| Smith Brandon S. | Chief Operating Officer | 0 0% | $19.96 | 0 | 5 | |
| Malecek Michael J | Chief Legal Officer | 0 0% | $19.96 | 0 | 13 | |
| EcoR1 Capital, LLC | 11584280 21.5862% | $19.96 | 9 | 1 | +87.11% | |
| Kinney Gene G. | President and CEO | 12793 0.0238% | $19.96 | 1 | 13 | +13.42% |
| Schenk Dale B. | President and CEO | 3333 0.0062% | $19.96 | 1 | 2 | +5.51% |
| Nguyen Tran | Chief Strategy Officer and CFO | 3200 0.006% | $19.96 | 2 | 10 | +10.25% |
| Nickerson Tara | Chief Business Officer | 2000 0.0037% | $19.96 | 1 | 7 | +5.51% |
| COLLIER RICHARD T | director | 1219 0.0023% | $19.96 | 0 | 6 | |
| Ekman Lars | director | 243 0.0005% | $19.96 | 0 | 6 | |
| Cooke Shane | director | 0 0% | $19.96 | 0 | 7 | |
| Koller Martin | Chief Medical Officer | 0 0% | $19.96 | 0 | 3 | |
| HOMAN ARTHUR W | Chief Legal Officer | 0 0% | $19.96 | 1 | 9 | +21.36% |
| PERRIGO Co plc | 10 percent owner | 0 0% | $19.96 | 0 | 1 | |
| HENNEY CHRISTOPHER S | director | 0 0% | $19.96 | 0 | 10 |
Institutional Investor Ownership
| Ecor1 Capital Llc | $286.94M | 21.54 | 11.58M | 0% | +$0 | 7.3 | |
| Fidelity Investments | $198.32M | 14.89 | 8.01M | -0.54% | -$1.07M | 0.01 | |
| T. Rowe Price | $104.08M | 7.81 | 4.2M | -0.84% | -$881,326.19 | 0.01 | |
| Wellington Management Company | $92.94M | 6.98 | 3.75M | +44.64% | +$28.68M | 0.02 | |
| BlackRock | $92.11M | 6.92 | 3.72M | -1.38% | -$1.28M | <0.01 | |
| State Street | $86.05M | 6.46 | 3.47M | +25.93% | +$17.72M | <0.01 | |
| Palo Alto Investors Lp | $41.2M | 3.09 | 1.66M | +0.2% | +$83,995.07 | 4.65 | |
| Janus Henderson | $32.44M | 2.44 | 1.31M | -35.68% | -$17.99M | 0.02 | |
| The Vanguard Group | $27.87M | 2.09 | 1.13M | +5.11% | +$1.36M | <0.01 | |
| Armistice Capital Llc | $27.15M | 2.04 | 1.1M | +294.25% | +$20.26M | 0.32 | |
| Artal Group S A | $24.8M | 1.86 | 1M | +99.73% | +$12.38M | 0.13 | |
| Geode Capital Management | $22.91M | 1.72 | 924,580 | +2.15% | +$481,974.26 | <0.01 | |
| Dimensional Fund Advisors | $21.37M | 1.61 | 862,832 | -0.55% | -$118,970.31 | 0.01 | |
| Boxer Capital, LLC | $17.09M | 1.28 | 690,000 | +3.76% | +$619,250.00 | 0.86 | |
| Morgan Stanley | $16.16M | 1.21 | 652,468 | +35.29% | +$4.22M | <0.01 | |
| ROCK SPRINGS CAPITAL MANAGEMENT, LP | $15.48M | 1.16 | 625,048 | 0% | +$0 | 0.39 | |
| First Light Asset Management | $11.02M | 0.83 | 444,953 | -59.13% | -$15.95M | 0.87 | |
| FINEPOINT CAPITAL LP | $9.97M | 0.75 | 402,400 | +15.2% | +$1.32M | 1.81 | |
| Northern Trust | $9.84M | 0.74 | 397,263 | -1.69% | -$169,600.18 | <0.01 | |
| Renaissance Technologies | $9.65M | 0.73 | 389,700 | +16.05% | +$1.34M | 0.02 | |
| Ubs Asset Management Americas Inc | $9.29M | 0.7 | 375,165 | +28.54% | +$2.06M | <0.01 | |
| Granahan Investment Management | $8.27M | 0.62 | 333,920 | -19.95% | -$2.06M | 0.29 | |
| Millennium Management LLC | $7.98M | 0.6 | 322,241 | +755.75% | +$7.05M | 0.01 | |
| Charles Schwab | $7.9M | 0.59 | 318,905 | +1.81% | +$140,569.75 | <0.01 | |
| Goldman Sachs | $7.65M | 0.57 | 308,887 | -7.46% | -$616,748.23 | <0.01 | |
| Rafferty Asset Management Llc | $7.52M | 0.56 | 303,455 | +46.3% | +$2.38M | 0.02 | |
| JPMorgan Chase | $7.38M | 0.55 | 298,091 | -16.84% | -$1.5M | <0.01 | |
| Citigroup | $6.44M | 0.48 | 259,872 | +196.72% | +$4.27M | 0.01 | |
| Nuveen | $6.02M | 0.45 | 243,022 | -19.21% | -$1.43M | <0.01 | |
| Bank of America | $5.95M | 0.45 | 240,343 | -16.36% | -$1.16M | <0.01 | |
| Citadel Advisors LLC | $5.82M | 0.44 | 234,926 | +69.52% | +$2.39M | <0.01 | |
| UBS | $4.92M | 0.37 | 198,680 | +49.95% | +$1.64M | <0.01 | |
| Qube Research & Technologies | $4.84M | 0.36 | 195,446 | -4.04% | -$204,005.70 | 0.01 | |
| Mariner Llc | $4.38M | 0.33 | 176,966 | -0.82% | -$36,114.66 | 0.01 | |
| Prosight Management Lp | $4.22M | 0.32 | 170,469 | -25.73% | -$1.46M | 1.18 | |
| Birchview Capital Lp | $4.2M | 0.32 | 169,574 | 0% | +$0 | 0.23 | |
| Systematic Financial Management LLC | $3.81M | 0.29 | 153,992 | +2.83% | +$104,851.77 | 0.11 | |
| BNY Mellon | $3.61M | 0.27 | 145,845 | -67.03% | -$7.34M | <0.01 | |
| Cubist Systematic Strategies | $3.35M | 0.25 | 135,321 | +1,269.78% | +$3.11M | 0.03 | |
| Connor Clark & Lunn Investment Management Ltd | $3.27M | 0.25 | 131,905 | -15.41% | -$595,396.52 | 0.01 | |
| Pinnacle Associates, Ltd. | $3.1M | 0.23 | 125,264 | -0.38% | -$11,963.91 | 0.05 | |
| AXA | $2.99M | 0.22 | 120,650 | +0.03% | +$817.41 | 0.01 | |
| Td Asset Management Inc | $2.88M | 0.22 | 116,338 | -20.61% | -$748,053.93 | <0.01 | |
| Dcf Advisers Llc | $2.65M | 0.2 | 107,000 | +27.38% | +$569,710.00 | 1.63 | |
| The Manufacturers Life Insurance Company | $2.05M | 0.15 | 82,581 | -3.55% | -$75,325.56 | <0.01 | |
| Swiss National Bank | $1.96M | 0.15 | 79,200 | 0% | +$0 | <0.01 | |
| RhumbLine Advisers | $1.57M | 0.12 | 63,500 | +2.55% | +$39,136.15 | <0.01 | |
| Credit Suisse | $1.49M | 0.11 | 60,202 | +1.51% | +$22,243.47 | <0.01 | |
| Susquehanna International Group | $1.49M | 0.11 | 59,980 | +78.53% | +$653,507.09 | <0.01 | |
| Barclays | $1.44M | 0.11 | 58,332 | -59.1% | -$2.09M | <0.01 |