| 2024-02-05 | Sale | Spero Therapeutics, Inc. SPRO | CEO and President | 45,093 0.0786% | $1.45 | $65,385 | +6.25% | |
| 2024-02-02 | Sale | Spero Therapeutics, Inc. SPRO | CEO and President | 30,901 0.0509% | $1.37 | $42,334 | +4.79% | |
| 2023-08-29 | Sale | Spero Therapeutics, Inc. SPRO | CEO and President | 4,163 0.0075% | $1.30 | $5,412 | +4.38% | |
| 2023-08-28 | Sale | Spero Therapeutics, Inc. SPRO | CEO and President | 1,854 0.0035% | $1.26 | $2,336 | +13.49% | |
| 2023-02-02 | Sale | Spero Therapeutics, Inc. SPRO | Chief Financial Officer | 9,504 0.0181% | $1.83 | $17,372 | -20.77% | |
| 2022-08-29 | Sale | Spero Therapeutics, Inc. SPRO | Chief Financial Officer | 6,017 0.017% | $0.89 | $5,378 | +96.02% |