| Rocket Pharmaceuticals, Inc. RCKT | $476.51M | 19.48 | 17.69M | 0% | +$0 | 7.05 | |
Orchestra BioMed Holdings, Inc. OBIO | $29.62M | 15.71 | 5.62M | 0% | +$0 | 0.44 | |
Immunocore Holdings plc IMCR | $391.28M | 12.04 | 6.02M | -1.26% | -$4.99M | 5.78 | |
| Taysha Gene Therapies, Inc. TSHA | $53.36M | 9.94 | 18.59M | +10.06% | +$4.88M | 0.79 | |
| Establishment Labs Holdings Inc. ESTA | $136.19M | 9.73 | 2.68M | +7.28% | +$9.24M | 2.01 | |
Immatics N.V. IMTX | $105.1M | 9.7 | 10M | +573.44% | +$89.49M | 1.55 | |
| PTC Therapeutics, Inc. PTCT | $215.96M | 9.68 | 7.42M | 0% | +$0 | 3.19 | |
CARGO Therapeutics, Inc. Common Stock CRGX | $83.38M | 9.49 | 3.74M | -27.83% | -$32.15M | 1.23 | |
| Axsome Therapeutics, Inc. AXSM | $358.52M | 9.46 | 4.49M | +0.07% | +$246,023.40 | 5.3 | |
| Fulcrum Therapeutics, Inc. FULC | $55.19M | 9.41 | 5.85M | +6.87% | +$3.55M | 0.82 | |
| Avadel Pharmaceuticals plc AVDL | $148.61M | 9.15 | 8.8M | +26.64% | +$31.26M | 2.2 | |
| Sage Therapeutics, Inc. SAGE | $102.71M | 9.11 | 5.48M | +5.46% | +$5.31M | 1.52 | |
| Protagonist Therapeutics, Inc. PTGX | $153.78M | 9.06 | 5.32M | 0% | +$0 | 2.27 | |
| UroGen Pharma Ltd. URGN | $48.86M | 9.02 | 3.26M | +88.63% | +$22.96M | 0.72 | |
| Tarsus Pharmaceuticals, Inc. TARS | $118.95M | 8.66 | 3.27M | +3.81% | +$4.36M | 1.76 | |
| Ultragenyx Pharmaceutical Inc. RARE | $330.9M | 8.53 | 7.09M | +2.9% | +$9.34M | 4.89 | |
| ACADIA Pharmaceuticals Inc. ACAD | $255.7M | 8.37 | 13.83M | +22.89% | +$47.63M | 3.78 | |
Avidity Biosciences, Inc. RNA | $203.4M | 8.33 | 7.97M | +19.14% | +$32.68M | 3.01 | |
| Stoke Therapeutics, Inc. STOK | $57.04M | 8.11 | 4.22M | +2.27% | +$1.27M | 0.84 | |
| Akero Therapeutics, Inc. AKRO | $137.21M | 7.86 | 5.43M | +51.19% | +$46.46M | 2.03 | |
| 89bio, Inc. ETNB | $85.89M | 7.5 | 7.38M | +32.26% | +$20.95M | 1.27 | |
| Merus N.V. MRUS | $185.05M | 7 | 4.11M | +73.13% | +$78.16M | 2.74 | |
GH Research PLC GHRS | $35.47M | 6.4 | 3.33M | 0% | +$0 | 0.52 | |
Neurogene Inc. NGNE | $39.15M | 5.93 | 769,122 | New | +$39.15M | 0.58 | |
Spyre Therapeutics, Inc. SYRE | $84.69M | 5.54 | 2.23M | 0% | +$0 | 1.25 | |
| ESSA Pharma Inc. EPIX | $19.52M | 5.18 | 2.3M | 0% | +$0 | 0.29 | |
| Arvinas, Inc. ARVN | $136.14M | 4.82 | 3.3M | -21.73% | -$37.8M | 2.01 | |
Kyverna Therapeutics, Inc. Common Stock KYTX | $46.02M | 4.3 | 1.85M | New | +$46.02M | 0.68 | |
Apogee Therapeutics, Inc. APGE | $163.97M | 4.22 | 2.47M | +15.17% | +$21.6M | 2.42 | |
| Alkermes plc ALKS | $163.89M | 3.58 | 6.05M | +55.18% | +$58.28M | 2.42 | |
LENZ Therapeutics, Inc. LENZ | $19.28M | 3.38 | 863,389 | New | +$19.28M | 0.29 | |
| Vericel Corporation VCEL | $83.56M | 3.31 | 1.61M | -50% | -$83.56M | 1.24 | |
Dyne Therapeutics, Inc. DYN | $87.77M | 3.17 | 3.09M | New | +$87.77M | 1.3 | |
| Masimo Corporation MASI | $214.75M | 2.76 | 1.46M | 0% | +$0 | 3.18 | |
| RadNet, Inc. RDNT | $82.75M | 2.3 | 1.7M | +156.26% | +$50.46M | 1.22 | |
| Bruker Corporation BRKR | $314.14M | 2.3 | 3.34M | 0% | +$0 | 4.64 | |
Dianthus Therapeutics, Inc. DNTH | $20M | 2.27 | 666,667 | New | +$20M | 0.3 | |
| Cytokinetics, Incorporated CYTK | $177.03M | 2.2 | 2.53M | 0% | +$0 | 2.62 | |
Natera, Inc. NTRA | $237.19M | 2.11 | 2.59M | 0% | +$0 | 3.51 | |
| Janux Therapeutics, Inc. JANX | $37.65M | 1.93 | 1M | New | +$37.65M | 0.56 | |
| Madrigal Pharmaceuticals, Inc. MDGL | $106.03M | 1.86 | 397,047 | -51.29% | -$111.66M | 1.57 | |
| Penumbra, Inc. PEN | $150.84M | 1.74 | 675,888 | +2% | +$2.95M | 2.23 | |
| 10x Genomics, Inc. TXG | $58.35M | 1.3 | 1.55M | +0.32% | +$184,084.65 | 0.86 | |
| Insmed Incorporated INSM | $50.6M | 1.26 | 1.87M | 0% | +$0 | 0.75 | |
argenx SE ARGX | $262.69M | 1.12 | 667,195 | 0% | +$0 | 3.88 | |
ShockWave Medical, Inc. SWAV | $94M | 0.77 | 288,684 | +343.72% | +$72.82M | 1.39 | |
CG Oncology, Inc. Common stock CGON | $18.16M | 0.62 | 413,670 | New | +$18.16M | 0.27 | |
| Stryker Corporation SYK | $114.88M | 0.08 | 321,000 | New | +$114.88M | 1.7 | |
| Thermo Fisher Scientific Inc. TMO | $64.22M | 0.03 | 110,500 | +121% | +$35.16M | 0.95 | |
| Intuitive Surgical, Inc. ISRG | $39.51M | 0.03 | 99,000 | New | +$39.51M | 0.58 |