Aldeyra Therapeutics, Inc., a biotechnology company, develops and commercializes medicines for immune-mediated ocular and systemic diseases. The company's lead product candidate is reproxalap, a reactive aldehyde species (RASP)modulator, which is in Phase III clinical trial for the treatment of dry eye diseases and allergic conjunctivitis. It also develops ADX-629, a first-in-class orally administered RASP modulator that is Phase II clinical trial for psoriasis, asthma, and COVID-19; and ADX-2191, a dihydrofolate reductase inhibitor which is in phase 3 for the prevention of proliferative vitreoretinopathy, and phase II clinical trial for the treatment of retinitis pigmentosa, as well as for treating primary vitreoretinal lymphoma. The company has a license agreement with Madrigal Pharmaceuticals, Inc. for developing ADX-1612, which inhibits the protein chaperome for the treatment of inflammatory diseases. The company was formerly known as Aldexa Therapeutics, Inc. and changed its name to Aldeyra Therapeutics, Inc. in March 2014. Aldeyra Therapeutics, Inc. was incorporated in 2004 and is based in Lexington, Massachusetts.
Over the last 12 months, insiders at Aldeyra Therapeutics, Inc. have bought $2.77M and sold $851,621 worth of Aldeyra Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Aldeyra Therapeutics, Inc. have bought $12.36M and sold $2.65M worth of stock each year.
Highest buying activity among insiders over the last 12 months: PERCEPTIVE ADVISORS LLC (10 percent owner) — $49.83M.
The last purchase of 37,712 shares for transaction amount of $178,755 was made by PERCEPTIVE ADVISORS LLC (10 percent owner) on 2024‑04‑05.
2024-08-12 | Sale | Chief Development Officer | 16,041 0.0272% | $4.74 | $75,975 | +12.84% | ||
2024-08-12 | Sale | See Remarks | 10,834 0.0184% | $4.74 | $51,313 | +12.84% | ||
2024-04-05 | 10 percent owner | 37,712 0.0643% | $4.74 | $178,755 | -6.57% | |||
2024-04-04 | 10 percent owner | 140,281 0.2374% | $4.67 | $655,112 | -5.56% | |||
2024-04-03 | 10 percent owner | 309,847 0.5185% | $4.09 | $1.27M | +6.75% | |||
2024-04-02 | 10 percent owner | 186,051 0.3061% | $3.44 | $640,015 | +24.51% | |||
2024-04-01 | 10 percent owner | 8,374 0.0141% | $3.25 | $27,216 | +34.86% | |||
2024-03-12 | Sale | President and CEO | 85,324 0.147% | $3.05 | $260,238 | +40.03% | ||
2024-03-12 | Sale | Chief Development Officer | 11,537 0.0206% | $3.16 | $36,503 | +40.03% | ||
2024-03-11 | Sale | President and CEO | 97,914 0.1675% | $3.27 | $320,521 | +29.54% | ||
2024-03-11 | Sale | Chief Development Officer | 18,231 0.0324% | $3.41 | $62,102 | +29.54% | ||
2024-03-11 | Sale | See Remarks | 13,201 0.0235% | $3.41 | $44,968 | +29.54% | ||
2023-10-18 | Sale | 10 percent owner | 306,499 0.5276% | $1.74 | $533,308 | +109.83% | ||
2023-10-16 | Sale | 10 percent owner | 2.45M 3.6657% | $1.60 | $3.92M | +98.09% | ||
2023-04-12 | director | 509 0.0009% | $10.13 | $5,156 | ||||
2022-08-09 | 15,000 0.027% | $7.85 | $117,750 | -4.83% | ||||
2022-08-08 | 97,000 0.1669% | $7.24 | $702,280 | -1.53% | ||||
2022-08-05 | 141,000 0.2422% | $6.95 | $979,950 | +2.46% | ||||
2022-08-04 | 95,100 0.1609% | $6.17 | $586,767 | +13.46% | ||||
2022-08-03 | 100,000 0.1722% | $5.84 | $584,000 | +21.64% |
PERCEPTIVE ADVISORS LLC | 10 percent owner | 9275851 15.5767% | $4.97 | 18 | 2 | +4.58% |
Brady Todd C | President and CEO | 1471298 2.4707% | $4.97 | 11 | 2 | +8.55% |
Machatha Stephen | Chief Development Officer | 236771 0.3976% | $4.97 | 0 | 3 | |
Greenberg Bruce | See Remarks | 126382 0.2122% | $4.97 | 0 | 2 | |
EDELMAN JOSEPH | 11350085 19.0599% | $4.97 | 9 | 0 | +19.29% | |
DOUGLAS RICHARD | director | 125000 0.2099% | $4.97 | 7 | 0 | +43% |
Reed Joshua | Chief Financial Officer | 35774 0.0601% | $4.97 | 1 | 0 | +5.74% |
JOYCE MARTIN JOSEPH | 23967 0.0402% | $4.97 | 5 | 0 | +39.85% | |
Bronstein Ben | director | 18644 0.0313% | $4.97 | 3 | 0 | +4.21% |
Clark David J | Chief Medical Officer | 17878 0.03% | $4.97 | 1 | 0 | +8.52% |
Clarke C. Boyd | director | 15500 0.026% | $4.97 | 2 | 0 | +69.19% |
Phillips Gary M. | director | 9375 0.0157% | $4.97 | 1 | 0 | +20.66% |
TREU JESSE I | director | 8763 0.0147% | $4.97 | 0 | 1 | |
Walker Neal | director | 6250 0.0105% | $4.97 | 1 | 0 | +20.66% |
McMullin David | Chief Commerical Officer | 6148 0.0103% | $4.97 | 1 | 0 | +5.74% |
Tulipano Stephen J | Chief Financial Officer | 3333 0.0056% | $4.97 | 1 | 0 | +0.98% |
Miller-Rich Nancy | director | 922 0.0015% | $4.97 | 2 | 0 |
Perceptive Advisors | $28.1M | 14.46 | 8.59M | 0% | +$0 | 0.02 | |
Tupelo Capital Management LLC | $17.9M | 9.22 | 5.48M | 0% | +$0 | 0.44 | |
The Vanguard Group | $12.65M | 6.51 | 3.87M | -1.49% | -$191,353.86 | <0.0001 | |
BlackRock | $10.83M | 5.57 | 3.31M | -3.5% | -$392,357.51 | <0.0001 | |
Kennedy Capital Management Inc | $4.31M | 2.22 | 1.32M | +3.29% | +$137,369.43 | 0.09 | |
Geode Capital Management | $3.36M | 1.73 | 1.03M | +0.55% | +$18,399.16 | <0.0001 | |
HERITAGE ASSET MANAGEMENT INC | $3.16M | 1.63 | 967,815 | -4.21% | -$139,037.13 | 0.02 | |
Verition Fund Management Llc | $3.08M | 1.58 | 940,398 | -29.02% | -$1.26M | 0.03 | |
State Street | $3.07M | 1.58 | 939,569 | +4.51% | +$132,631.22 | <0.0001 | |
Dimensional Fund Advisors | $2.88M | 1.49 | 882,210 | -15.06% | -$511,565.39 | <0.01 | |
Renaissance Technologies | $2.38M | 1.23 | 727,690 | +142.56% | +$1.4M | <0.01 | |
D. E. Shaw & Co. | $1.79M | 0.92 | 547,640 | +110.58% | +$940,399.79 | <0.01 | |
Acadian Asset Management | $1.48M | 0.76 | 452,449 | +106.33% | +$761,685.37 | 0.01 | |
Bank of America | $1.3M | 0.67 | 398,951 | +6.69% | +$81,851.32 | <0.0001 | |
Northern Trust | $1.27M | 0.66 | 389,187 | -0.97% | -$12,491.40 | <0.0001 | |
Millennium Management LLC | $1.27M | 0.65 | 388,705 | -11.74% | -$169,003.36 | <0.01 | |
Wells Fargo | $1.27M | 0.65 | 387,304 | +12.22% | +$137,964.56 | <0.0001 | |
Los Angeles Capital Management LLC | $1.25M | 0.64 | 380,773 | +240.85% | +$879,829.68 | <0.01 | |
Two Sigma Advisers LP | $1.23M | 0.63 | 374,900 | +6.69% | +$76,845.00 | <0.01 | |
Morgan Stanley | $1.14M | 0.59 | 349,546 | -16.79% | -$230,606.86 | <0.0001 | |
Johnson & Johnson | $979,918.00 | 0.5 | 299,669 | 0% | +$0 | 0.02 | |
Deutsche Bank | $956,105.00 | 0.49 | 292,387 | -1.7% | -$16,510.22 | <0.0001 | |
Two Sigma | $781,412.00 | 0.4 | 238,964 | +18.57% | +$122,373.17 | <0.01 | |
Palo Alto Investors Lp | $737,271.00 | 0.38 | 225,465 | 0% | +$0 | 0.08 | |
Jacobs Levy Equity Management | $585,065.00 | 0.3 | 178,919 | New | +$585,065.00 | <0.01 | |
Woodstock Corporation | $558,238.00 | 0.29 | 170,715 | +46.28% | +$176,615.95 | 0.06 | |
BNY Mellon | $525,938.00 | 0.27 | 160,837 | -5.41% | -$30,090.60 | <0.0001 | |
Nuveen | $424,197.00 | 0.22 | 129,724 | 0% | +$0 | <0.0001 | |
Ameriprise Financial | $412,595.00 | 0.21 | 126,176 | -23.96% | -$129,988.88 | <0.0001 | |
Charles Schwab | $410,467.00 | 0.21 | 125,525 | 0% | +$0 | <0.0001 | |
Sherbrooke Park Advisers Llc | $352,336.00 | 0.18 | 107,748 | New | +$352,336.00 | 0.07 | |
AQR Capital | $343,527.00 | 0.18 | 105,054 | New | +$343,527.00 | <0.01 | |
Simplex Trading Llc | $305,000.00 | 0.16 | 93,465 | +333.15% | +$234,585.51 | 0.01 | |
Goldman Sachs | $299,915.00 | 0.15 | 91,717 | -37.81% | -$182,345.26 | <0.0001 | |
Ohio Strs | $269,000.00 | 0.14 | 82,300 | -5.94% | -$16,996.35 | <0.01 | |
RhumbLine Advisers | $209,512.00 | 0.11 | 64,074 | +3.57% | +$7,229.63 | <0.0001 | |
Cornercap Investment Counsel Inc | $201,435.00 | 0.1 | 61,601 | 0% | +$0 | 0.03 | |
International Assets Investment Management Llc | $197,181.00 | 0.1 | 60,300 | +3.08% | +$5,886.00 | <0.01 | |
Citadel Advisors LLC | $180,661.00 | 0.09 | 55,248 | -18.43% | -$40,812.88 | <0.0001 | |
AllianceBernstein | $164,939.00 | 0.09 | 50,440 | 0% | +$0 | <0.0001 | |
T. Rowe Price | $158,000.00 | 0.08 | 48,273 | +7.69% | +$11,278.93 | <0.0001 | |
UBS | $157,993.00 | 0.08 | 48,316 | -8.97% | -$15,568.44 | <0.0001 | |
Denali Advisors | $154,671.00 | 0.08 | 47,300 | New | +$154,671.00 | 0.05 | |
Susquehanna International Group | $130,529.00 | 0.07 | 39,917 | -80.26% | -$530,654.00 | <0.0001 | |
Squarepoint Ops LLC | $124,891.00 | 0.06 | 38,193 | -47.66% | -$113,701.07 | <0.0001 | |
Raymond James Associates | $117,798.00 | 0.06 | 36,024 | +9.88% | +$10,594.76 | <0.0001 | |
First Manhattan Co. | $113,616.00 | 0.06 | 34,745 | 0% | +$0 | <0.0001 | |
Barclays | $106,000.00 | 0.06 | 32,487 | -49.12% | -$102,348.88 | <0.0001 | |
Invesco | $104,071.00 | 0.05 | 31,826 | +0.19% | +$199.47 | <0.0001 | |
Joseph P. Lucia & Associates LLC | $92,384.00 | 0.05 | 28,252 | 0% | +$0 | 0.06 |