Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops therapeutics for autoimmune, neurodegenerative, and ophthalmic disorders. The company's C1q is an initiating molecule of the classical complement pathway that targets distinct disease processes, such as antibody-mediated autoimmune disease and complement-mediated neurodegeneration. Its product candidates include ANX005, a monoclonal antibody, which is in Phase II/III clinical trials to treat patients with guillain- barré syndrome; Phase II trial in patients with warm autoimmune hemolytic anemia; and Phase II clinical trial for Huntington's disease and amyotrophic lateral sclerosis. The company is also developing ANX009 that is in Phase Ib trial in patients with lupus nephritis; and ANX007, which is in Phase II clinical trials to treat patients with geographic atrophy. In addition, it develops ANX105, an investigational monoclonal antibody targeting neurodegenerative indications; and ANX1502, an investigational oral small molecule for the treatment of certain autoimmune indications. The company was incorporated in 2011 and is headquartered in Brisbane, California.
Over the last 12 months, insiders at Annexon, Inc. have bought $1.06M and sold $205,748 worth of Annexon, Inc. stock.
On average, over the past 5 years, insiders at Annexon, Inc. have bought $14.75M and sold $773,526 worth of stock each year.
Highest buying activity among insiders over the last 12 months: Satter Muneer A () — $6.05M. Carson William H. (director) — $49,853.
The last purchase of 3,200 shares for transaction amount of $15,459 was made by Carson William H. (director) on 2024‑06‑03.
2024-06-03 | Carson William H. | director | 3,200 0.0037% | $4.83 | $15,459 | +22.71% | ||
2024-05-01 | Carson William H. | director | 3,200 0.0035% | $4.68 | $14,982 | +2.53% | ||
2024-04-08 | Carson William H. | director | 3,200 0.0036% | $6.07 | $19,411 | -20.25% | ||
2024-02-20 | Sale | Overdorf Michael | EVP & CHIEF BUSINESS OFFICER | 1,951 0.0026% | $5.48 | $10,691 | -1.54% | |
2024-02-20 | Sale | Lew Jennifer | EVP & CHIEF FINANCIAL OFFICER | 2,593 0.0035% | $5.53 | $14,339 | -1.54% | |
2024-02-20 | Sale | Yednock Ted | EVP & CHIEF INNOVATION OFFICER | 2,604 0.0035% | $5.51 | $14,348 | -1.54% | |
2024-02-12 | Sale | Love Douglas | PRESIDENT AND CEO | 5,782 0.0076% | $5.54 | $32,032 | -4.97% | |
2024-02-12 | Sale | Overdorf Michael | EVP & CHIEF BUSINESS OFFICER | 1,349 0.0018% | $5.53 | $7,460 | -4.97% | |
2024-02-12 | Sale | Lew Jennifer | EVP & CHIEF FINANCIAL OFFICER | 1,809 0.0024% | $5.54 | $10,022 | -4.97% | |
2024-02-12 | Sale | Yednock Ted | EVP & CHIEF INNOVATION OFFICER | 1,810 0.0024% | $5.54 | $10,027 | -4.97% | |
2023-12-27 | Sale | Yednock Ted | EVP & Chief Innovation Officer | 21,000 0.0389% | $4.52 | $94,966 | +5.82% | |
2023-12-26 | Satter Muneer A | 350,000 0.4308% | $2.88 | $1.01M | +11.62% | |||
2023-07-11 | Sale | Lew Jennifer | EVP & Chief Financial Officer | 1,057 0.0015% | $3.84 | $4,055 | +13.93% | |
2023-07-11 | Sale | Overdorf Michael | EVP & Chief Business Officer | 978 0.0014% | $3.84 | $3,752 | +13.93% | |
2023-07-11 | Sale | Yednock Ted | EVP & Chief Innovation Officer | 1,057 0.0015% | $3.84 | $4,055 | +13.93% | |
2023-05-25 | Bain Capital Life Sciences Investors, LLC | 10 percent owner | 300,000 0.4125% | $2.13 | $639,720 | +64.76% | ||
2023-02-15 | Sale | Love Douglas | President & CEO | 6,571 0.0089% | $5.87 | $38,564 | -41.52% | |
2023-02-14 | Sale | Lew Jennifer | EVP & Chief Financial Officer | 166 0.0002% | $6.30 | $1,046 | -41.23% | |
2023-02-14 | Sale | Overdorf Michael | EVP & Chief Business Officer | 144 0.0002% | $6.30 | $907 | -41.23% | |
2023-02-13 | Sale | Lew Jennifer | EVP & Chief Financial Officer | 1,742 0.0024% | $6.31 | $10,989 | -45.50% |
Satter Muneer A | 7406024 9.4539% | $4.65 | 3 | 0 | <0.0001% | |
Love Douglas | President & CEO | 196121 0.2523% | $4.65 | 1 | 9 | +135.71% |
Lew Jennifer | EVP & Chief Financial Officer | 82058 0.0606% | $4.65 | 1 | 8 | +33.07% |
Overdorf Michael | EVP & Chief Business Officer | 85641 0.0585% | $4.65 | 0 | 5 | |
Yednock Ted | EVP & Chief Innovation Officer | 72471 0.0484% | $4.65 | 0 | 7 | |
Carson William H. | director | 9600 0.003% | $4.65 | 3 | 0 | |
Bain Capital Life Sciences Investors, LLC | 10 percent owner | 5701926 7.2786% | $4.65 | 2 | 0 | +48.92% |
Clarus Lifesciences III, L.P. | 10 percent owner | 2730635 3.4857% | $4.65 | 1 | 0 | +33.07% |
Flynn James E | 10 percent owner | 808914 1.0326% | $4.65 | 1 | 0 | +33.07% |
Keswani Sanjay | EVP & Chief Medical Officer | 0 0% | $4.65 | 0 | 1 |
Fidelity Investments | $67.2M | 10.14 | 9.37M | -3.23% | -$2.24M | 0.01 | |
Bain Capital Life Sciences Investors Llc | $62.4M | 9.42 | 8.7M | +7.96% | +$4.6M | 6.27 | |
Alerce Investment Management L P | $53.1M | 8.01 | 7.41M | 0% | +$0 | 59.28 | |
Bvf Inc Il | $50.19M | 7.58 | 7M | 0% | +$0 | 0.37 | |
Redmile Group | $39.46M | 5.96 | 5.5M | 0% | +$0 | 1.46 | |
Point72 Asset Management | $36.97M | 5.58 | 5.16M | New | +$36.97M | 0.07 | |
BlackRock | $36.16M | 5.46 | 5.04M | +51.98% | +$12.37M | <0.01 | |
Adage Capital Partners Gp L L C | $30.97M | 4.68 | 4.32M | -13.6% | -$4.88M | 0.06 | |
The Vanguard Group | $26.87M | 4.06 | 3.75M | +96.38% | +$13.19M | <0.01 | |
Logos Global Management Lp | $21.87M | 3.3 | 3.05M | -38.38% | -$13.62M | 2.35 | |
GMT Capital | $18.97M | 2.86 | 2.65M | -12.41% | -$2.69M | 0.78 | |
Bellevue Group | $15.65M | 2.36 | 2.18M | New | +$15.65M | 0.24 | |
Octagon Capital Advisors LP | $14.7M | 2.22 | 2.05M | 0% | +$0 | 1.92 | |
Woodline Partners LP | $14.34M | 2.17 | 2M | +0.03% | +$4,366.53 | 0.14 | |
Geode Capital Management | $10.25M | 1.55 | 1.43M | +55% | +$3.64M | <0.01 | |
Ikarian Capital LLC | $10.07M | 1.52 | 1.41M | -46.98% | -$8.93M | 2.87 | |
T. Rowe Price | $9.49M | 1.43 | 1.32M | +10,482.01% | +$9.4M | <0.01 | |
Millennium Management LLC | $9.16M | 1.38 | 1.28M | +57.6% | +$3.35M | 0.01 | |
State Street | $8.59M | 1.3 | 1.2M | +41.58% | +$2.52M | <0.0001 | |
Polar Capital | $7.17M | 1.08 | 1M | New | +$7.17M | 0.04 | |
JPMorgan Chase | $6.88M | 1.04 | 959,648 | +3,143.7% | +$6.67M | <0.01 | |
Acadian Asset Management | $6.87M | 1.04 | 957,993 | +9.61% | +$601,899.10 | 0.02 | |
Morgan Stanley | $6.45M | 0.97 | 899,513 | +368.35% | +$5.07M | <0.0001 | |
Invesco | $5.66M | 0.85 | 789,044 | +3,524.12% | +$5.5M | <0.01 | |
Kennedy Capital Management Inc | $5.55M | 0.84 | 774,698 | -27.98% | -$2.16M | 0.12 | |
Massachusetts Financial Services Co Ma | $5.55M | 0.84 | 773,914 | -0.52% | -$29,067.18 | <0.01 | |
Schonfeld Group | $5.46M | 0.82 | 761,600 | +4,380% | +$5.34M | 0.04 | |
Renaissance Technologies | $4.81M | 0.73 | 671,200 | +38.62% | +$1.34M | 0.01 | |
Deerfield Management | $4.19M | 0.63 | 583,913 | 0% | +$0 | 0.08 | |
Goldman Sachs | $4.04M | 0.61 | 562,966 | +97.58% | +$1.99M | <0.01 | |
Northern Trust | $3.98M | 0.6 | 555,566 | +51.27% | +$1.35M | <0.01 | |
Caption Management Llc | $3.58M | 0.54 | 500,000 | New | +$3.58M | 0.11 | |
Board Of Trustees Of The Leland Stanford Junior University | $3.46M | 0.52 | 482,550 | 0% | +$0 | 0.3 | |
D. E. Shaw & Co. | $2.72M | 0.41 | 379,254 | New | +$2.72M | <0.01 | |
Boothbay Fund Management LLC | $2.69M | 0.41 | 375,276 | -46.98% | -$2.38M | 0.09 | |
Two Sigma | $2.68M | 0.4 | 373,448 | +1,304.84% | +$2.49M | 0.01 | |
Parkman Healthcare Partners Llc | $2.49M | 0.38 | 346,687 | New | +$2.49M | 0.31 | |
Dimensional Fund Advisors | $2.39M | 0.36 | 333,913 | +283.6% | +$1.77M | <0.01 | |
Marshall Wace | $2.26M | 0.34 | 315,612 | New | +$2.26M | <0.01 | |
ExodusPoint Capital Management, LP | $2.26M | 0.34 | 315,155 | -8.1% | -$199,241.14 | 0.03 | |
Nuveen | $2.21M | 0.33 | 308,058 | +58.3% | +$813,508.62 | <0.01 | |
Soleus Capital Management, L.P. | $2.1M | 0.32 | 292,400 | -43.27% | -$1.6M | 0.02 | |
Driehaus Capital Management LLC | $0 | 0.28 | 258,314 | 0% | +$0 | <0.0001 | |
Citadel Advisors LLC | $1.85M | 0.28 | 258,675 | -75.54% | -$5.73M | <0.01 | |
Ubs Oconnor Llc | $1.78M | 0.27 | 248,277 | -64.17% | -$3.19M | 0.15 | |
Jump Financial Llc | $1.51M | 0.23 | 210,200 | New | +$1.51M | 0.01 | |
Two Sigma Advisers LP | $1.39M | 0.21 | 194,400 | +129.25% | +$785,832.00 | <0.01 | |
Charles Schwab | $1.3M | 0.2 | 181,051 | +46.4% | +$411,436.22 | <0.0001 | |
BNY Mellon | $1.3M | 0.2 | 180,616 | +34.51% | +$332,250.70 | <0.0001 | |
Bridgeway Capital Management | $1.27M | 0.19 | 177,500 | -1.11% | -$14,340.00 | 0.02 |