Arvinas, Inc., a clinical-stage biopharmaceutical company, engages in the discovery, development, and commercialization of therapies to degrade disease-causing proteins. Its lead product candidates include Bavdegalutamide, a proteolysis targeting chimera (PROTAC) protein degrader that is in phase I clinical trial targeting the androgen receptor (AR) protein for the treatment of men with metastatic castration-resistant prostate cancer (mCRPC); ARV-471, a PROTAC protein degrader targeting the estrogen receptor protein for the treatment of patients with metastatic ER positive/HER2 negative breast cancer; and ARV-766 an investigational orally bioavailable PROTAC protein degrader for the treatment of men with mCRPC. The company has collaborations with Pfizer Inc., Genentech, Inc., F. Hoffman-La Roche Ltd., and Bayer AG. Arvinas, Inc. was founded in 2013 and is based in New Haven, Connecticut.
Over the last 12 months, insiders at Arvinas, Inc. have bought $0 and sold $516,809 worth of Arvinas, Inc. stock.
On average, over the past 5 years, insiders at Arvinas, Inc. have bought $25.51M and sold $37.2M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 285,714 shares for transaction amount of $20M was made by Ratcliffe Liam (director) on 2020‑12‑18.
2024-02-23 | Sale | Houston John G | President and CEO | 5,196 0.0095% | $47.05 | $244,472 | -26.62% | |
2024-02-23 | Sale | Cassidy Sean A | Chief Financial Officer | 1,702 0.0031% | $47.05 | $80,079 | -26.62% | |
2024-02-23 | Sale | Taylor Ian | Chief Scientific Officer | 1,701 0.0031% | $47.05 | $80,032 | -26.62% | |
2024-02-23 | Sale | Peck Ronald | Chief Medical Officer | 1,699 0.0031% | $47.05 | $79,938 | -26.62% | |
2023-08-11 | Sale | Peck Ronald | Chief Medical Officer | 1,324 0.0024% | $24.39 | $32,289 | +29.90% | |
2023-03-01 | Sale | Houston John G | President and CEO | 5,878 0.0107% | $29.53 | $173,577 | -14.21% | |
2023-03-01 | Sale | Cassidy Sean A | Chief Financial Officer | 1,745 0.0032% | $29.53 | $51,530 | -14.21% | |
2023-03-01 | Sale | Taylor Ian | Chief Scientific Officer | 1,051 0.0019% | $29.53 | $31,036 | -14.21% | |
2022-08-12 | Sale | Peck Ronald | Chief Medical Officer | 1,258 0.0024% | $54.84 | $68,994 | -40.58% | |
2022-04-14 | Sale | Morrison Briggs | 10,754 0.0202% | $67.03 | $720,888 | -36.79% | ||
2022-03-11 | Sale | Cassidy Sean A | Chief Financial Officer | 15,000 0.029% | $70.00 | $1.05M | -36.08% | |
2022-03-04 | Sale | Houston John G | President and CEO | 6,024 0.0113% | $63.94 | $385,175 | -31.76% | |
2022-03-04 | Sale | Cassidy Sean A | Chief Financial Officer | 1,593 0.003% | $63.94 | $101,856 | -31.76% | |
2022-03-04 | Sale | Taylor Ian | Chief Scientific Officer | 869 0.0016% | $63.94 | $55,564 | -31.76% | |
2022-02-15 | Sale | Taylor Ian | Chief Scientific Officer | 20,000 0.0378% | $73.02 | $1.46M | -38.58% | |
2022-01-14 | Sale | Morrison Briggs | director | 20,960 0.0385% | $65.55 | $1.37M | -29.61% | |
2021-12-30 | Sale | Peck Ronald | Chief Medical Officer | 20,000 0.0382% | $80.61 | $1.61M | -38.61% | |
2021-12-17 | Sale | Cassidy Sean A | Chief Financial Officer | 15,000 0.0271% | $70.00 | $1.05M | -32.08% | |
2021-12-16 | Sale | Ratcliffe Liam | director | 85,705 0.1636% | $69.36 | $5.94M | -27.43% | |
2021-12-15 | Sale | Ratcliffe Liam | director | 113,536 0.2076% | $66.81 | $7.58M | -27.70% |
Houston John G | President and CEO | 1036681 1.6673% | $25.87 | 1 | 10 | +24.92% |
Cassidy Sean A | Chief Financial Officer | 181916 0.3337% | $25.87 | 1 | 13 | +24.92% |
Taylor Ian | Chief Scientific Officer | 147522 0.1849% | $25.87 | 1 | 12 | +66.46% |
Peck Ronald | Chief Medical Officer | 67516 0.0545% | $25.87 | 0 | 8 | |
RA CAPITAL MANAGEMENT, LLC | 3138412 5.7036% | $25.87 | 1 | 0 | +24.92% | |
SHANNON TIMOTHY M | director | 1653128 3.0043% | $25.87 | 5 | 11 | +35.38% |
Flynn James E | 10 percent owner | 411245 0.7474% | $25.87 | 1 | 0 | +24.92% |
Loven Jakob | director | 312500 0.5679% | $25.87 | 1 | 0 | +24.92% |
Ratcliffe Liam | director | 185686 0.3375% | $25.87 | 3 | 10 | +24.96% |
5AM VENTURES III, L.P. | 10 percent owner | 91162 0.1657% | $25.87 | 0 | 4 | |
Kennedy Edward Moore Jr. | director | 42718 0.0776% | $25.87 | 2 | 0 | +130.98% |
Morrison Briggs | 19976 0.0363% | $25.87 | 1 | 2 | <0.0001% | |
Margus Bradley Albert | director | 2000 0.0036% | $25.87 | 1 | 5 | +24.92% |
Ecor1 Capital Llc | $277.67M | 9.83 | 6.73M | 0% | +$0 | 7.06 | |
The Vanguard Group | $260.05M | 9.21 | 6.3M | +29.85% | +$59.78M | 0.01 | |
BlackRock | $226.8M | 8.03 | 5.49M | +2.6% | +$5.75M | 0.01 | |
T. Rowe Price | $180.33M | 6.38 | 4.37M | +13.99% | +$22.14M | 0.02 | |
RTW Investments, LP | $136.14M | 4.82 | 3.3M | -21.73% | -$37.8M | 2.01 | |
Avidity Partners Management Lp | $123.23M | 4.36 | 2.99M | +<0.01% | +$3,013.44 | 4.47 | |
Paradigm BioCapital Advisors LP | $107.94M | 3.82 | 2.61M | +180.78% | +$69.5M | 3.92 | |
Bellevue Group | $98.69M | 3.49 | 2.39M | -4.66% | -$4.83M | 1.51 | |
Fidelity Investments | $98.62M | 3.49 | 2.39M | +6.46% | +$5.98M | 0.01 | |
Citadel Advisors LLC | $94.14M | 3.33 | 2.28M | -6.53% | -$6.58M | 0.06 | |
JPMorgan Chase | $70.17M | 2.48 | 1.7M | -21.77% | -$19.52M | 0.01 | |
Nextech Invest | $58.14M | 2.06 | 1.41M | -16.94% | -$11.86M | 9.48 | |
State Street | $57.06M | 2.02 | 1.38M | +16.49% | +$8.08M | <0.01 | |
Geode Capital Management | $54.22M | 1.92 | 1.31M | +16.99% | +$7.87M | 0.01 | |
New Leaf Venture Partners | $53.23M | 1.88 | 1.29M | 0% | +$0 | 46.65 | |
Commodore Capital, LP | $52.63M | 1.86 | 1.27M | +27.5% | +$11.35M | 3.71 | |
Perceptive Advisors | $51.05M | 1.81 | 1.24M | +249.24% | +$36.43M | 0.03 | |
Arrowmark Colorado Holdings Llc | $49.77M | 1.76 | 1.21M | -23.21% | -$15.04M | 0.12 | |
Morgan Stanley | $27.89M | 0.99 | 675,509 | -2.59% | -$741,801.59 | <0.01 | |
Adage Capital Partners Gp L L C | $26.01M | 0.92 | 630,000 | -20.2% | -$6.58M | 0.05 | |
Vr Adviser Llc | $25.92M | 0.92 | 627,788 | 0% | +$0 | 1.26 | |
Boxer Capital, LLC | $25.12M | 0.89 | 608,614 | 0% | +$0 | 1.26 | |
Goldman Sachs | $24.54M | 0.87 | 594,403 | +80.42% | +$10.94M | 0.01 | |
FINEPOINT CAPITAL LP | $22.25M | 0.79 | 539,100 | +6.82% | +$1.42M | 4.04 | |
Charles Schwab | $21.8M | 0.77 | 528,055 | +12.48% | +$2.42M | 0.01 | |
Northern Trust | $21.02M | 0.74 | 509,127 | +3.64% | +$738,581.74 | <0.01 | |
Candriam S C A | $19.09M | 0.68 | 462,554 | -5.13% | -$1.03M | 0.12 | |
Dimensional Fund Advisors | $17.93M | 0.64 | 434,300 | -11.71% | -$2.38M | 0.01 | |
Woodline Partners LP | $17.43M | 0.62 | 422,204 | +8.92% | +$1.43M | 0.17 | |
RA Capital Management, L.P. | $17.39M | 0.62 | 421,348 | 0% | +$0 | 0.02 | |
Spyglass Capital Management LLC | $16.75M | 0.59 | 405,766 | -17.05% | -$3.44M | 12.56 | |
Voloridge Investment Management, LLC | $15.66M | 0.55 | 379,376 | +22.51% | +$2.88M | 0.04 | |
Renaissance Technologies | $14.94M | 0.53 | 361,973 | +52.36% | +$5.14M | 0.02 | |
Opaleye Management Inc | $13.62M | 0.48 | 330,000 | +25.14% | +$2.74M | 2.15 | |
American Century Investments | $13.44M | 0.48 | 325,518 | -17.67% | -$2.88M | 0.01 | |
Gilder Gagnon Howe & Co. LLC | $13.41M | 0.48 | 324,844 | -2.6% | -$358,310.39 | 0.17 | |
D. E. Shaw & Co. | $12.53M | 0.44 | 303,638 | +257.51% | +$9.03M | 0.02 | |
Nuveen | $12.22M | 0.43 | 296,017 | -17.36% | -$2.57M | <0.01 | |
UBS | $12.14M | 0.43 | 294,044 | +14.42% | +$1.53M | <0.01 | |
Frazier Life Sciences Management L P | $11.78M | 0.42 | 285,331 | 0% | +$0 | 0.61 | |
Schonfeld Group | $11.6M | 0.41 | 281,097 | +14.33% | +$1.45M | 0.08 | |
Nordea Investment Management Ab | $11.56M | 0.4 | 276,482 | -0.81% | -$94,259.00 | 0.01 | |
Brown Advisory | $11.32M | 0.4 | 274,175 | +3.29% | +$360,952.32 | 0.02 | |
Franklin Templeton Investments | $11.07M | 0.39 | 268,153 | +1,662.89% | +$10.44M | <0.01 | |
Credit Suisse | $10.82M | 0.38 | 262,224 | +84.52% | +$4.96M | 0.01 | |
Millennium Management LLC | $10.06M | 0.36 | 243,667 | -32.09% | -$4.75M | 0.01 | |
Wasatch Advisors | $8.56M | 0.3 | 207,426 | -6.96% | -$640,500.46 | 0.05 | |
Td Asset Management Inc | $8.23M | 0.29 | 199,348 | +35.66% | +$2.16M | 0.01 | |
Ubs Asset Management Americas Inc | $8.03M | 0.28 | 194,496 | -16.39% | -$1.57M | <0.01 | |
Amundi | $6.63M | 0.28 | 193,341 | -1.22% | -$81,575.91 | <0.01 |