Arrowhead Pharmaceuticals, Inc. (ARWR) Insider Trading Activity

NASDAQ$82.85
Market Cap
$11.67B
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
431 of 852
Rank in Industry
254 of 491

ARWR Insider Trading Activity

ARWR Median Price and Trade Amounts History Chart

Statistics of Insider Transactions

Amount of Insider Buys and Sells

Buys
$0
0
0
Sells
$38,494,096
23
100

Related Transactions

Lu Hongbodirector
0
$0
1
$228,334
$-228,334
Waddill William D.director
0
$0
1
$566,038
$-566,038
Vakiener Victoriadirector
0
$0
1
$679,491
$-679,491
OLUKOTUN ADEOYE Ydirector
0
$0
2
$850,543
$-850,543
Apel Daniel JosephChief Financial Officer
0
$0
1
$934,285
$-934,285
Ferrari Maurodirector
0
$0
2
$1.02M
$-1.02M
PERRY MICHAEL Sdirector
0
$0
2
$2M
$-2M
O'Brien PatrickCOO
0
$0
1
$3.12M
$-3.12M
Hamilton James CChief Medical Officer
0
$0
5
$5.08M
$-5.08M
Anzalone Christopher RichardChief Executive Officer
0
$0
7
$24.01M
$-24.01M

About Arrowhead Pharmaceuticals, Inc.

Arrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena, California, is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for complex and challenging-to-treat diseases within the United States. The company's extensive therapeutic pipeline primarily leverages RNA interference (RNAi) technology. Among its advanced clinical programs are: ARO-AAT, a Phase II therapeutic targeting liver diseases associated with alpha-1 antitrypsin deficiency; ARO-APOC3, which is undergoing both Phase 2b and Phase 3 clinical evaluations for hypertriglyceridemia; ARO-ANG3, currently in Phase 2b development to reduce the production of angiopoietin-like protein 3; and ARO-HIF2, a Phase 1b candidate designed to treat clear cell renal cell carcinoma. Arrowhead also has several compounds in earlier clinical development, including ARO-HSD in Phase 1/2a for other liver diseases, ARO-ENaC in Phase 1/2a, aimed at decreasing the epithelial sodium channel alpha subunit in lung airways, and ARO-C3, also in Phase 1/2a, for complement-mediated diseases. Further expanding its diverse portfolio, the company is actively developing ARO-Lung2 for chronic obstructive pulmonary disorder (COPD), ARO-DUX4 for facioscapulohumeral muscular dystrophy, ARO-XDH for uncontrolled gout, and ARO-COV for COVID-19 and other pulmonary-borne pathogens. Beyond its core internal programs, Arrowhead is involved in the progression of JNJ-3989, a subcutaneously administered RNAi therapeutic for chronic hepatitis B virus infection; Olpasiran, intended to reduce apolipoprotein A production; and ARO-AMG1, which targets genetically validated cardiovascular pathways. Strategic collaborations are integral to Arrowhead's development efforts. The company holds a licensing and research agreement with Janssen Pharmaceuticals, Inc. for the co-development of ARO-JNJ1, ARO-JNJ2, and ARO-JNJ3, all RNAi therapeutics focused on liver-expressed targets. Additionally, Arrowhead has a licensing and research partnership with Takeda Pharmaceuticals U.S.A., Inc. to develop an RNAi therapeutic candidate specifically for liver disease.

Insider Activity of Arrowhead Pharmaceuticals, Inc.

Over the last 12 months, insiders at Arrowhead Pharmaceuticals, Inc. have bought $0 and sold $38.49M worth of Arrowhead Pharmaceuticals, Inc. stock.

On average, over the past 5 years, insiders at Arrowhead Pharmaceuticals, Inc. have bought $63,231 and sold $19.36M worth of stock each year.

There was no buying activity among insiders over the last 12 months.

The last purchase of 1,000 shares for transaction amount of $27,500 was made by Lu Hongbo (director) on 2024‑03‑20.

List of Insider Buy and Sell Transactions, Arrowhead Pharmaceuticals, Inc.

2026-08-18SalePERRY MICHAEL Sdirector
11,600
0.0082%
$87.30
$1.01M
-1.77%
2026-08-18SaleOLUKOTUN ADEOYE Ydirector
2,000
0.0014%
$86.96
$173,920
-1.77%
2026-05-12SaleLu Hongbodirector
2,970
0.0021%
$76.88
$228,334
+3.99%
2026-04-23SaleHamilton James CChief Medical Officer
10,000
0.0072%
$75.00
$750,000
+7.39%
2026-04-22SaleApel Daniel JosephChief Financial Officer
13,095
0.009%
$71.35
$934,285
+8.03%
2026-03-05SaleHamilton James CChief Medical Officer
10,000
0.0072%
$64.19
$641,900
+20.36%
2026-01-05SaleO'Brien PatrickCOO
49,493
0.0354%
$63.11
$3.12M
+14.91%
2026-01-05SaleHamilton James CChief Medical Officer
40,164
0.0287%
$63.11
$2.53M
+14.91%
2026-01-02SaleAnzalone Christopher RichardChief Executive Officer
13,187
0.0095%
$66.10
$871,703
+8.17%
2025-12-29SaleAnzalone Christopher RichardChief Executive Officer
51,726
0.0369%
$69.13
$3.58M
+5.05%
2025-12-26SaleFerrari Maurodirector
7,530
0.0054%
$70.00
$527,100
+4.18%
2025-12-22SaleAnzalone Christopher RichardChief Executive Officer
12,586
0.009%
$68.44
$861,340
+5.57%
2025-12-19SaleAnzalone Christopher RichardChief Executive Officer
13,445
0.0097%
$67.66
$909,683
+6.65%
2025-12-19SaleWaddill William D.director
8,367
0.006%
$67.65
$566,038
+6.65%
2025-12-19SaleVakiener Victoriadirector
10,040
0.0072%
$67.68
$679,491
+6.65%
2025-12-19SaleOLUKOTUN ADEOYE Ydirector
10,000
0.0072%
$67.66
$676,623
+6.65%
2025-12-17SaleAnzalone Christopher RichardChief Executive Officer
85,000
0.0608%
$64.04
$5.44M
+11.96%
2025-12-16SaleAnzalone Christopher RichardChief Executive Officer
54,298
0.0359%
$62.58
$3.4M
+11.89%
2025-12-15SaleAnzalone Christopher RichardChief Executive Officer
130,000
0.0946%
$68.85
$8.95M
+5.39%
2025-12-05SalePERRY MICHAEL Sdirector
16,250
0.0117%
$61.03
$991,738
+16.62%
Total: 261
*Gray background shows transactions not older than one year

Insider Historical Profitability

18.58%
Anzalone Christopher RichardChief Executive Officer
3792739
2.6926%
$314.23M451
<0.0001%
O'Brien PatrickCOO
474908
0.3372%
$39.35M014
Hamilton James CChief Medical Officer
226958
0.1611%
$18.8M021
Apel Daniel JosephChief Financial Officer
162905
0.1157%
$13.5M01
PERRY MICHAEL Sdirector
111459
0.0791%
$9.23M07
Ferrari Maurodirector
69053
0.049%
$5.72M26
+71%
Waddill William D.director
56563
0.0402%
$4.69M010
Lu Hongbodirector
52012
0.0369%
$4.31M31
<0.0001%
Vakiener Victoriadirector
35723
0.0254%
$2.96M05
OLUKOTUN ADEOYE Ydirector
31600
0.0224%
$2.62M07
GIVEN BRUCE DChief Operating Officer
850730
0.604%
$70.48M019
Myszkowski Kenneth AllenChief Financial Officer
455433
0.3233%
$37.73M129
<0.0001%
Li ZhenSnr. VP, Chem and Non-Clin Dev
201700
0.1432%
$16.71M01
San Martin JavierChief Medical Officer
198497
0.1409%
$16.45M05
KNOTT DAVID M10 percent owner
166778
0.1184%
$13.82M13
<0.0001%
Leone Peter BrianVP, Strategic Bus. Initiatives
130000
0.0923%
$10.77M01
Oliver TracieChief Commercial Officer
127107
0.0902%
$10.53M03
GIVEN DOUGLAS Bdirector
124167
0.0882%
$10.29M121
<0.0001%
Hassard JamesChief Commercial Officer
105750
0.0751%
$8.76M02
FRYKMAN EDWARD Wdirector
23852
0.0169%
$1.98M01
McKenney Charlesdirector
17220
0.0122%
$1.43M116
De Backer Mariannedirector
17000
0.0121%
$1.41M92
+50.28%
Kingsley Joseph Theodore IIIInterim President & CFO
12000
0.0085%
$994,200.0020
+27.7%
Ching Marshall Robert10 percent owner
0
0%
$006
Lewis David L.Chief Scientific Officer
0
0%
$003
Bradshaw CurtChief Scientific Officer
0
0%
$002
*Gray background shows insiders who have made transactions during last year

Historical Insider Profitability vs. Competitors

$159,914,414
243
18.52%
$12.19B
$273,531,368
93
38.24%
$12.35B
$2,765,836
72
20.00%
$12.69B
$108,876,545
67
72.81%
$12.72B
$98,300,471
40
0.27%
$15.44B
$19,233,721
36
70.14%
$14.11B
$13,655,378
35
17.13%
$21.1B
Arrowhead Pharmaceuticals, Inc.
(ARWR)
$1,801,511
23
18.58%
$11.67B
$415,090,639
19
-14.04%
$14.19B
$1,479,484
17
50.46%
$11.36B
$639,489,927
17
128.14%
$14B
$11,859,102
17
18.62%
$9.18B
$118,094,211
15
38.32%
$9.46B
$9,976,473
12
29.52%
$9.33B
$762,720
11
52.96%
$9.01B
$11,898,979
10
54.58%
$10.23B
$35,908,794
10
126.31%
$9.53B
$948,235
8
15.54%
$11.29B
$41,376,000
4
-12.07%
$8.59B

ARWR Institutional Investors: Active Positions

Increased Positions248+75.15%15M+13.53%
Decreased Positions145-43.94%13M-11.05%
New Positions123New6MNew
Sold Out Positions29Sold Out872,791Sold Out
Total Postitions433+31.21%117M+2.48%

ARWR Ownership Change vs Market

Institutional Investor Ownership

Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
Active Shareholders
Blackrock, Inc.$1.37M14.87%20.22M+799,938+4.12%2025-09-30
Vanguard Group Inc$1.09M11.79%16.04M+510,798+3.29%2025-09-30
Avoro Capital Advisors Llc$738,911.008.02%10.9M+300,000+2.83%2025-09-30
State Street Corp$433,677.004.7%6.4M+26,308+0.41%2025-09-30
Fmr Llc$390,459.004.24%5.76M+589,520+11.4%2025-09-30
Slate Path Capital Lp$337,730.003.66%4.98M-250,000-4.78%2025-09-30
Geode Capital Management, Llc$212,253.002.3%3.13M+152,537+5.12%2025-09-30
Siren, L.L.C.$180,991.001.96%2.67M00%2025-09-30
Driehaus Capital Management Llc$142,318.001.54%2.1M+2MNew2025-09-30
Arrowstreet Capital, Limited Partnership$141,118.001.53%2.08M+2M+3,142.51%2025-09-30

Financial Ratios

Summary
Comparison with Competitors

Price to Earnings

Price/Earnings to Growth

Price to Sales

Price to Book

Price/Free Cash Flow

Analyst Recommendations

Analyst Price Targets

Prismo does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.
Information is provided 'as-is' and solely for informational purposes and is not advice. Prismo does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.