Clene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. Its lead drug is CNM-Au8, which is being studied in various clinical trials, including a Phase 2/3 registrational clinical trial for patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; completed two open-label investigator blinded Phase 2 clinical trials on the brain's energy metabolites; ongoing Phase 2 clinical trial for the treatment of visual pathway deficits in chronic optic neuropathy for remyelination in stable relapsing Multiple Sclerosis; and a planned Phase 2 clinical trial for the treatment of patients with Parkinson's Diseases. The company's products also include CNM-AgZn17, a gel polymer suspension of silver and zinc ions that is being developed for the treatment of infectious diseases and to accelerate wound healing; CNM-ZnAg, a broad-spectrum antiviral and antibacterial agent to treat infection disease, such as COVID-19 and to provide immune support for symptom resolution; and CNM-PtAu7, a gold-platinum CSN therapeutic for oncology applications. It also markets and distributes dietary supplements comprising rMetx, an aqueous zinc-silver ion dietary supplement; and KHC46, an aqueous gold dietary supplement of very low-concentration Au nanoparticles. The company is headquartered in Salt Lake City, Utah.
Over the last 12 months, insiders at Clene Inc. have bought $375,915 and sold $22,516 worth of Clene Inc. stock.
On average, over the past 5 years, insiders at Clene Inc. have bought $5.97M and sold $530,982 worth of stock each year.
Highest buying activity among insiders over the last 12 months: Stevens John Henry (director) — $253,164. MATLIN DAVID J (director) — $205,002. Etherington Robert Dee (Chief Executive Officer) — $20,250.
The last purchase of 250,002 shares for transaction amount of $102,501 was made by MATLIN DAVID J (director) on 2023‑11‑10.
2024-05-01 | Sale | General Resonance LLC | 10 percent owner | 13,000 0.0092% | $0.40 | $5,148 | -12.88% | |
2024-04-30 | Sale | General Resonance LLC | 10 percent owner | 13,000 0.0098% | $0.42 | $5,416 | -11.44% | |
2024-04-24 | Sale | General Resonance LLC | 10 percent owner | 10,000 0.0076% | $0.33 | $3,278 | +13.10% | |
2024-04-09 | Sale | General Resonance LLC | 10 percent owner | 22,500 0.0172% | $0.39 | $8,675 | -6.84% | |
2023-11-10 | MATLIN DAVID J | director | 250,002 0.1815% | $0.41 | $102,501 | -7.48% | ||
2023-06-26 | Stevens John Henry | director | 316,455 0.4161% | $0.80 | $253,164 | -45.02% | ||
2023-06-26 | Etherington Robert Dee | Chief Executive Officer | 25,000 0.0333% | $0.81 | $20,250 | -45.02% | ||
2023-06-16 | Ugwumba Chidozie | 10 percent owner | 7.5M 9.259% | $0.80 | $6M | -47.65% | ||
2023-06-16 | MATLIN DAVID J | director | 1.5M 1.8518% | $0.80 | $1.2M | -47.65% | ||
2023-06-16 | Mosca Alison | director | 2.39M 2.9559% | $0.80 | $1.92M | -47.65% | ||
2023-06-16 | Gay Jonathon | director | 105,625 0.1304% | $0.80 | $84,500 | -47.65% | ||
2022-11-02 | Ugwumba Chidozie | director | 990,099 1.4746% | $1.01 | $1,000,000 | -7.69% | ||
2022-11-02 | MATLIN DAVID J | director | 2.87M 4.2765% | $1.01 | $2.9M | -7.69% | ||
2022-11-02 | Gay Jonathon | director | 990,099 1.4746% | $1.01 | $1,000,000 | -7.69% | ||
2022-11-02 | Mosca Alison | director | 792,079 1.1797% | $1.01 | $800,000 | -7.69% | ||
2022-11-02 | Stevens John Henry | director | 148,515 0.2212% | $1.01 | $150,000 | -7.69% | ||
2022-08-17 | Stevens John Henry | 47,662 0.0756% | $3.85 | $183,499 | -72.25% | |||
2022-07-18 | Sale | Etherington Robert Dee | Chief Executive Officer | 23,483 0.0361% | $4.72 | $110,840 | -76.81% | |
2022-06-16 | Sale | Mortenson Mark | Chief Science Officer | 20,247 0.0304% | $2.47 | $50,010 | -52.69% | |
2022-06-16 | MATLIN DAVID J | 74,610 0.1137% | $2.51 | $187,271 | -52.69% |
General Resonance LLC | 15313712 12.117% | $0.35 | 0 | 7 | ||
MATLIN DAVID J | director | 7043686 5.4851% | $0.35 | 21 | 0 | <0.0001% |
Stevens John Henry | director | 800204 0.6231% | $0.35 | 3 | 0 | <0.0001% |
Etherington Robert Dee | Chief Executive Officer | 25000 0.0195% | $0.35 | 1 | 1 | |
Ugwumba Chidozie | 10 percent owner | 13018908 10.1381% | $0.35 | 2 | 0 | <0.0001% |
Mosca Alison | director | 3238375 2.5218% | $0.35 | 4 | 0 | <0.0001% |
Mortenson Mark | Chief Science Officer | 168759 0.1314% | $0.35 | 0 | 1 | |
Gay Jonathon | director | 105625 0.0823% | $0.35 | 3 | 0 | <0.0001% |
Glanzman Robert | Chief Medical Officer | 10564 0.0082% | $0.35 | 0 | 1 |
The Vanguard Group | $1.11M | 2.04 | 2.62M | +0.05% | +$559.40 | <0.0001 | |
Geode Capital Management | $402,758.00 | 0.74 | 946,532 | +54.69% | +$142,397.90 | <0.0001 | |
Scoggin Management Lp | $212,700.00 | 0.39 | 500,000 | -33.33% | -$106,350.00 | 0.16 | |
Alyeska Investment Group L P | $201,695.00 | 0.37 | 474,130 | -71.89% | -$515,908.35 | <0.01 | |
Morgan Stanley | $144,055.00 | 0.26 | 338,635 | 0% | +$0 | <0.0001 | |
Laird Norton Trust Company Llc | $114,254.00 | 0.21 | 268,581 | 0% | +$0 | 0.02 | |
Citadel Advisors LLC | $100,072.00 | 0.18 | 235,241 | -16.39% | -$19,610.18 | <0.0001 | |
BlackRock | $76,576.00 | 0.14 | 180,009 | -61.22% | -$120,902.78 | <0.0001 | |
Northern Trust | $71,988.00 | 0.13 | 169,225 | +2.25% | +$1,585.03 | <0.0001 | |
Group One Trading | $60,573.00 | 0.11 | 142,391 | +3,567.98% | +$58,921.60 | <0.01 | |
State Street | $54,471.00 | 0.1 | 128,046 | 0% | +$0 | <0.0001 | |
Csenge Advisory Group | $49,602.00 | 0.09 | 116,600 | 0% | +$0 | <0.01 | |
GOLDEN CAPITAL MANAGEMENT LLC | $24,693.00 | 0.05 | 58,046 | 0% | +$0 | <0.01 | |
SRS Capital Advisors, Inc. | $23,504.00 | 0.04 | 55,250 | 0% | +$0 | <0.01 | |
Ci Private Wealth Llc | $21,270.00 | 0.04 | 50,000 | 0% | +$0 | <0.0001 | |
EP Wealth Advisors | $19,136.00 | 0.04 | 44,984 | New | +$19,136.00 | <0.0001 | |
Susquehanna International Group | $17,727.00 | 0.03 | 41,672 | -5.2% | -$972.02 | <0.0001 | |
Hrt Financial Llc | $14,000.00 | 0.03 | 33,018 | New | +$14,000.00 | <0.0001 | |
Bank of America | $13,735.00 | 0.03 | 32,319 | +51.05% | +$4,642.08 | <0.0001 | |
TWO SIGMA SECURITIES LLC | $13,398.00 | 0.03 | 31,495 | New | +$13,398.00 | <0.0001 | |
LINSCO PRIVATE LEDGER CORP | $12,595.00 | 0.02 | 29,607 | +51% | +$4,254.06 | <0.0001 | |
Charles Schwab | $10,929.00 | 0.02 | 25,692 | 0% | +$0 | <0.0001 | |
Xtx Topco Ltd | $10,655.00 | 0.02 | 25,047 | New | +$10,655.00 | <0.01 | |
Key Client Fiduciary Advisors Llc | $11,060.00 | 0.02 | 26,000 | New | +$11,060.00 | <0.01 | |
Lincoln National Corporation | $8,657.00 | 0.02 | 20,350 | New | +$8,657.00 | <0.0001 | |
Millennium Management LLC | $8,620.00 | 0.02 | 20,263 | -63.13% | -$14,758.61 | <0.0001 | |
Renaissance Technologies | $8,000.00 | 0.02 | 19,424 | New | +$8,000.00 | <0.0001 | |
Pallas Capital Advisors | $7,377.00 | 0.01 | 17,341 | 0% | +$0 | <0.0001 | |
Advisor Group Holdings Inc | $6,913.00 | 0.01 | 16,250 | 0% | +$0 | <0.0001 | |
Vontobel Holding Ltd | $6,381.00 | 0.01 | 15,000 | New | +$6,381.00 | <0.0001 | |
Coastal Investment Advisors Inc | $6,806.00 | 0.01 | 16,000 | 0% | +$0 | <0.01 | |
Tower Research Capital | $4,179.00 | 0.01 | 9,832 | -62.35% | -$6,921.79 | <0.0001 | |
Cutler Group Lp | $1,000.00 | <0.01 | 3,900 | 0% | +$0 | <0.01 | |
Simplex Trading Llc | $1,000.00 | <0.01 | 2,678 | -8.79% | -$96.34 | <0.0001 | |
Washington Trust Co | $1,276.00 | <0.01 | 3,000 | 0% | +$0 | <0.0001 | |
Wells Fargo | $312.00 | <0.01 | 733 | +1.66% | +$5.11 | <0.0001 | |
Royal Bank of Canada | $0 | <0.01 | 118 | -79.19% | -$0 | <0.0001 | |
Qube Research & Technologies | $1.00 | <0.01 | 2 | 0% | +$0 | <0.0001 | |
JPMorgan Chase | $6.00 | <0.01 | 15 | 0% | +$0 | <0.0001 | |
UBS | $72.00 | <0.01 | 170 | +0.59% | +$0.42 | <0.0001 | |
U.S. Bancorp | $170.00 | <0.01 | 400 | 0% | +$0 | <0.0001 |