| $385M | ||
| $350M | ||
| $215M | ||
| $88M | ||
| $82M | ||
| $62M |
Buys | $0 | 0 | 0 |
Sells | $2,953,792 | 1 | 100 |
| William Arsani | director | 0 | $0 | 1 | $2.95M | $-2.95M |
Design Therapeutics, Inc. a preclinical-stage biopharmaceutical company, engages in the development of therapies for the treatment of genetic diseases caused by nucleotide repeat expansions. The company's portfolio of products comprises Friedreich Ataxia, a monogenic, autosomal recessive, progressive multi-system disease that affects organ systems dependent on mitochondrial function, eventually leading to neurological, cardiac, and metabolic dysfunction; and Myotonic Dystrophy Type-1 (DM1), a dominantly-inherited, monogenic progressive neuromuscular disease affecting skeletal muscle, heart, brain, and other organs. It is also developing GeneTAC product candidate portfolio for the treatment of other nucleotide repeat expansion-driven monogenic diseases, such as Fragile X syndrome, spinocerebellar ataxias, amyotrophic lateral sclerosis, frontotemporal dementia, Huntington disease, and spinobulbar muscular atrophy. Design Therapeutics, Inc. was incorporated in 2017 and is headquartered in Carlsbad, California.
Over the last 12 months, insiders at Design Therapeutics, Inc. have bought $0 and sold $2.95M worth of Design Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Design Therapeutics, Inc. have bought $15.55M and sold $2.24M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 17,809 shares for transaction amount of $66,606 was made by Schmid John P. (director) on 2024‑03‑25.
| 2025-08-13 | Sale | William Arsani | director | 562,627 0.957% | $5.25 | $2.95M | +38.01% | |
| 2024-12-18 | Sale | Prasad Deepa | director | 3,806 0.0073% | $6.27 | $23,864 | -18.32% | |
| 2024-08-09 | Sale | William Arsani | director | 814,874 1.4426% | $4.25 | $3.46M | +11.32% | |
| 2024-03-25 | Schmid John P. | director | 17,809 0.0318% | $3.74 | $66,606 | +27.01% | ||
| 2024-03-25 | Berger Heather A. | director | 1,300 0.0023% | $3.74 | $4,866 | +27.01% | ||
| 2024-03-22 | Schmid John P. | director | 9,156 0.0156% | $3.62 | $33,133 | +25.00% | ||
| 2023-09-29 | LAPPE RODNEY W | director | 21,000 0.0373% | $2.35 | $49,287 | +41.10% | ||
| 2023-08-29 | William Arsani | director | 1.96M 3.6838% | $2.44 | $4.78M | +19.26% | ||
| 2023-08-29 | Prasad Deepa | director | 12,000 0.0213% | $2.31 | $27,670 | +19.26% | ||
| 2023-08-28 | William Arsani | director | 275,000 0.48% | $2.15 | $591,250 | +24.09% | ||
| 2022-12-20 | SR One Capital Fund I Aggregator LP | director | 40,000 0.0725% | $8.14 | $325,432 | -27.67% | ||
| 2022-12-20 | George Simeon | director | 40,000 0.0725% | $8.14 | $325,432 | -27.67% | ||
| 2022-12-20 | Siffert Joao MD | President and CEO | 6,300 0.0118% | $8.38 | $52,763 | -27.67% | ||
| 2022-12-19 | SR One Capital Fund I Aggregator LP | director | 360,000 0.6698% | $8.63 | $3.11M | -29.29% | ||
| 2022-12-19 | George Simeon | director | 360,000 0.6698% | $8.63 | $3.11M | -29.29% | ||
| 2022-12-19 | Siffert Joao MD | President and CEO | 1,150 0.0021% | $8.47 | $9,741 | -29.29% | ||
| 2022-12-16 | SR One Capital Fund I Aggregator LP | director | 500,000 0.8485% | $8.28 | $4.14M | -32.02% | ||
| 2022-12-16 | George Simeon | director | 500,000 0.8485% | $8.28 | $4.14M | -32.02% | ||
| 2022-12-09 | LAPPE RODNEY W | director | 15,000 0.0273% | $7.96 | $119,426 | -21.76% | ||
| 2022-03-21 | William Arsani | 25,000 0.0461% | $18.99 | $474,680 | -22.95% |
| William Arsani | director | 1000000 1.7555% | $10.12M | 5 | 2 | <0.0001% |
| George Simeon | director | 6526476 11.4572% | $66.05M | 4 | 0 | <0.0001% |
| SR One Capital Fund I Aggregator LP | director | 6526476 11.4572% | $66.05M | 4 | 0 | <0.0001% |
| Cormorant Asset Management, LP | 5114844 8.9791% | $51.76M | 1 | 0 | <0.0001% | |
| Xu Stella | 4155405 7.2948% | $42.05M | 1 | 1 | <0.0001% | |
| LAPPE RODNEY W | director | 133024 0.2335% | $1.35M | 3 | 0 | +0.06% |
| Siffert Joao MD | President and CEO | 132619 0.2328% | $1.34M | 2 | 0 | |
| Schmid John P. | director | 26965 0.0473% | $272,885.80 | 2 | 0 | +26% |
| Shah Pratik | Executive Chairperson | 25000 0.0439% | $253,000.00 | 1 | 0 | <0.0001% |
| Prasad Deepa | director | 20000 0.0351% | $202,400.00 | 1 | 1 | +19.26% |
| Thacker Justin | Vice President, Finance | 17500 0.0307% | $177,100.00 | 1 | 0 | <0.0001% |
| Jeffries Sean | Chief Operating Officer | 3050 0.0054% | $30,866.00 | 1 | 0 | <0.0001% |
| Berger Heather A. | director | 1300 0.0023% | $13,156.00 | 1 | 0 | +27.01% |
$3,611,891 | 113 | 13.40% | $568.07M | |
$860,541,348 | 82 | -5.10% | $522.02M | |
$63,049,419 | 31 | 2.87% | $591.5M | |
Design Therapeutics, Inc. (DSGN) | $46,858,891 | 18 | -11.58% | $576.47M |
$3,556,951 | 18 | 9.64% | $497.63M | |
$59,102,045 | 17 | 8.52% | $602.76M | |
$7,254,955 | 14 | 20.70% | $645.28M | |
$8,069,667 | 13 | -13.57% | $506.32M | |
$92,357,691 | 12 | 87.24% | $669.7M | |
$140,543,039 | 10 | 0.77% | $610.12M | |
$75,069,528 | 10 | 19.77% | $568.45M | |
$19,167,169 | 10 | 28.48% | $576.83M | |
$94,000,000 | 7 | -20.84% | $597.49M | |
$49,165,200 | 7 | 12.92% | $599.48M | |
$1,746,565 | 4 | -29.05% | $510.69M | |
$58,352 | 4 | -43.78% | $495.18M | |
$7,234,370 | 3 | -3.34% | $651.27M | |
$2,857,000 | 2 | -5.23% | $517.81M | |
$300,016 | 1 | -50.33% | $539.17M |
| Increased Positions | 44 | +39.64% | 6M | +16.38% |
| Decreased Positions | 43 | -38.74% | 3M | -9.25% |
| New Positions | 21 | New | 3M | New |
| Sold Out Positions | 9 | Sold Out | 165,662 | Sold Out |
| Total Postitions | 112 | +0.9% | 36M | +7.12% |
| Sr One Capital Management, Lp | $59,391.00 | 11.45% | 6.53M | 0 | 0% | 2025-09-30 |
| Logos Global Management Lp | $33,261.00 | 6.41% | 3.65M | -562,627 | -13.34% | 2025-09-30 |
| Point72 Asset Management, L.P. | $30,399.00 | 5.86% | 3.34M | +2M | +84.84% | 2025-09-30 |
| Blackrock, Inc. | $18,604.00 | 3.59% | 2.04M | -351,355 | -14.67% | 2025-09-30 |
| Frazier Life Sciences Management, L.P. | $17,777.00 | 3.43% | 1.95M | 0 | 0% | 2025-09-30 |
| Tang Capital Management Llc | $16,207.00 | 3.13% | 1.78M | 0 | 0% | 2025-09-30 |
| Baker Bros. Advisors Lp | $15,587.00 | 3.01% | 1.71M | 0 | 0% | 2025-09-30 |
| Almitas Capital Llc | $13,927.00 | 2.69% | 1.53M | 0 | 0% | 2025-09-30 |
| Vanguard Group Inc | $13,138.00 | 2.53% | 1.44M | -27,873 | -1.89% | 2025-09-30 |
| Driehaus Capital Management Llc | $9,794.00 | 1.89% | 1.08M | 0 | 0% | 2025-09-30 |