Design Therapeutics, Inc. (DSGN)
Largest Insider Buys in Sector
DSGN Stock Price History Chart
DSGN Stock Performance
About Design Therapeutics, Inc.
Design Therapeutics, Inc. a preclinical-stage biopharmaceutical company, engages in the development of therapies for the treatment of genetic diseases caused by nucleotide repeat expansions. The company's portfolio of products comprises Friedreich Ataxia, a monogenic, autosomal recessive, progressive multi-system disease that affects organ systems dependent on mitochondrial function, eventually leading to neurological, cardiac, and metabolic dysfunction; and Myotonic Dystrophy Type-1 (DM1), a dominantly-inherited, monogenic progressive neuromuscular disease affecting skeletal muscle, heart, brain, and other organs. It is also developing GeneTAC product candidate portfolio for the treatment of other nucleotide repeat expansion-driven monogenic diseases, such as Fragile X syndrome, spinocerebellar ataxias, amyotrophic lateral sclerosis, frontotemporal dementia, Huntington disease, and spinobulbar muscular atrophy. Design Therapeutics, Inc. was incorporated in 2017 and is headquartered in Carlsbad, California.
Insider Activity of Design Therapeutics, Inc.
Over the last 12 months, insiders at Design Therapeutics, Inc. have bought $5.56M and sold $0 worth of Design Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Design Therapeutics, Inc. have bought $15.55M and sold $268,488 worth of stock each year.
Highest buying activity among insiders over the last 12 months: William Arsani (director) — $5.37M. Schmid John P. (director) — $199,477. LAPPE RODNEY W (director) — $49,287.
The last purchase of 17,809 shares for transaction amount of $66,606 was made by Schmid John P. (director) on 2024‑03‑25.
List of Insider Buy and Sell Transactions, Design Therapeutics, Inc.
| 2024-03-25 | Schmid John P. | director | 17,809 0.0318% | $3.74 | $66,606 | +2.14% | ||
| 2024-03-25 | Berger Heather A. | director | 1,300 0.0023% | $3.74 | $4,866 | +2.14% | ||
| 2024-03-22 | Schmid John P. | director | 9,156 0.0156% | $3.62 | $33,133 | -0.52% | ||
| 2023-09-29 | LAPPE RODNEY W | director | 21,000 0.0373% | $2.35 | $49,287 | +11.02% | ||
| 2023-08-29 | William Arsani | director | 1.96M 3.6838% | $2.44 | $4.78M | +11.90% | ||
| 2023-08-29 | Prasad Deepa | director | 12,000 0.0213% | $2.31 | $27,670 | +11.90% | ||
| 2023-08-28 | William Arsani | director | 275,000 0.48% | $2.15 | $591,250 | +17.50% | ||
| 2022-12-20 | SR One Capital Fund I Aggregator LP | director | 40,000 0.0725% | $8.14 | $325,432 | -27.73% | ||
| 2022-12-20 | George Simeon | director | 40,000 0.0725% | $8.14 | $325,432 | -27.73% | ||
| 2022-12-20 | Siffert Joao MD | President and CEO | 6,300 0.0118% | $8.38 | $52,763 | -27.73% | ||
| 2022-12-19 | SR One Capital Fund I Aggregator LP | director | 360,000 0.6698% | $8.63 | $3.11M | -29.65% | ||
| 2022-12-19 | George Simeon | director | 360,000 0.6698% | $8.63 | $3.11M | -29.65% | ||
| 2022-12-19 | Siffert Joao MD | President and CEO | 1,150 0.0021% | $8.47 | $9,741 | -29.65% | ||
| 2022-12-16 | SR One Capital Fund I Aggregator LP | director | 500,000 0.8485% | $8.28 | $4.14M | -32.42% | ||
| 2022-12-16 | George Simeon | director | 500,000 0.8485% | $8.28 | $4.14M | -32.42% | ||
| 2022-12-09 | LAPPE RODNEY W | director | 15,000 0.0273% | $7.96 | $119,426 | -22.01% | ||
| 2022-03-21 | William Arsani | 25,000 0.0461% | $18.99 | $474,680 | -22.95% | |||
| 2022-03-18 | Sale | Xu Stella | 13,200 0.0246% | $20.34 | $268,488 | -26.91% | ||
| 2021-08-31 | William Arsani | director | 40,000 0.0713% | $15.45 | $618,000 | +0.60% | ||
| 2021-03-30 | SR One Capital Fund I Aggregator LP | 10 percent owner | 250,000 0.9607% | $20.00 | $5M | -40.99% |
Insider Historical Profitability
| William Arsani | director | 3000000 5.357% | $3.23 | 5 | 0 | <0.0001% |
| LAPPE RODNEY W | director | 133024 0.2375% | $3.23 | 3 | 0 | <0.0001% |
| Schmid John P. | director | 26965 0.0482% | $3.23 | 2 | 0 | |
| Prasad Deepa | director | 23806 0.0425% | $3.23 | 1 | 0 | |
| Berger Heather A. | director | 1300 0.0023% | $3.23 | 1 | 0 | |
| George Simeon | director | 6526476 11.654% | $3.23 | 4 | 0 | <0.0001% |
| SR One Capital Fund I Aggregator LP | director | 6526476 11.654% | $3.23 | 4 | 0 | <0.0001% |
| Cormorant Asset Management, LP | 5114844 9.1333% | $3.23 | 1 | 0 | <0.0001% | |
| Xu Stella | 4155405 7.4201% | $3.23 | 1 | 1 | <0.0001% | |
| Siffert Joao MD | President and CEO | 132619 0.2368% | $3.23 | 2 | 0 | <0.0001% |
| Shah Pratik | Executive Chairperson | 25000 0.0446% | $3.23 | 1 | 0 | <0.0001% |
| Thacker Justin | Vice President, Finance | 17500 0.0312% | $3.23 | 1 | 0 | <0.0001% |
| Jeffries Sean | Chief Operating Officer | 3050 0.0054% | $3.23 | 1 | 0 | <0.0001% |
Institutional Investor Ownership
| Sr One Capital Management Lp | $26.3M | 11.55 | 6.53M | 0% | +$0 | 7.22 | |
| Logos Global Management Lp | $20.28M | 8.91 | 5.03M | 0% | +$0 | 2.18 | |
| BlackRock | $9.16M | 4.03 | 2.27M | -4.46% | -$427,385.50 | <0.0001 | |
| Baker Bros Advisors LP | $6.7M | 2.94 | 1.66M | +10.81% | +$653,343.64 | 0.08 | |
| Tang Capital Management, LLC | $5.97M | 2.62 | 1.48M | +0.02% | +$1,209.00 | 0.02 | |
| The Vanguard Group | $5.18M | 2.28 | 1.29M | +28.96% | +$1.16M | <0.0001 | |
| Almitas Capital LLC | $4.14M | 1.82 | 1.03M | 0% | +$0 | 2.17 | |
| Bml Capital Management Llc | $3.54M | 1.56 | 879,478 | -14.57% | -$604,499.94 | 2.7 | |
| Citadel Advisors LLC | $3.53M | 1.55 | 874,777 | -52.26% | -$3.86M | <0.01 | |
| State Street | $2.82M | 1.24 | 698,986 | +0.54% | +$15,160.86 | <0.0001 | |
| Geode Capital Management | $2.76M | 1.21 | 683,898 | +3.19% | +$85,258.08 | <0.0001 | |
| Point72 Asset Management | $2.39M | 1.05 | 593,516 | New | +$2.39M | 0.01 | |
| Goldman Sachs | $2.04M | 0.9 | 506,256 | -50.55% | -$2.09M | <0.0001 | |
| Jacobs Levy Equity Management | $2.02M | 0.89 | 502,020 | -8.58% | -$189,804.98 | 0.01 | |
| Millennium Management LLC | $1.95M | 0.86 | 484,468 | +15.33% | +$259,552.14 | <0.01 | |
| Morgan Stanley | $1.93M | 0.85 | 478,092 | -12.03% | -$263,517.84 | <0.0001 | |
| Renaissance Technologies | $1.83M | 0.8 | 453,400 | -30.12% | -$787,374.94 | <0.01 | |
| D. E. Shaw & Co. | $1.8M | 0.79 | 446,190 | +53.53% | +$626,914.96 | <0.01 | |
| Two Sigma | $1.7M | 0.75 | 422,035 | -1.43% | -$24,728.08 | <0.01 | |
| Two Sigma Advisers LP | $1.63M | 0.72 | 404,000 | -30.94% | -$729,430.00 | <0.01 | |
| Acadian Asset Management | $1.63M | 0.71 | 403,546 | +123.27% | +$897,191.71 | 0.01 | |
| Northern Trust | $1.44M | 0.63 | 357,284 | -4.2% | -$63,041.31 | <0.0001 | |
| Assenagon Asset Management S.A. | $1.4M | 0.62 | 347,794 | +41.83% | +$413,345.06 | <0.01 | |
| Prescott Group Capital Management LLC | $1.38M | 0.61 | 343,000 | 0% | +$0 | 0.16 | |
| Gsa Capital Partners Llp | $872,000.00 | 0.38 | 216,347 | +199.27% | +$580,622.61 | 0.07 | |
| Wellington Management Company | $863,669.00 | 0.38 | 214,310 | New | +$863,669.00 | <0.0001 | |
| Walleye Capital | $784,041.00 | 0.34 | 194,551 | -46.31% | -$676,379.48 | <0.01 | |
| Charles Schwab | $722,055.00 | 0.32 | 179,170 | +2.01% | +$14,205.75 | <0.0001 | |
| Nuveen | $636,757.00 | 0.28 | 158,004 | 0% | +$0 | <0.0001 | |
| Bridgeway Capital Management | $587,977.00 | 0.26 | 145,900 | 0% | +$0 | 0.01 | |
| Shay Capital Llc | $517,069.00 | 0.23 | 128,305 | New | +$517,069.00 | 0.15 | |
| BNY Mellon | $464,425.00 | 0.2 | 115,242 | -4.59% | -$22,366.49 | <0.0001 | |
| Opaleye Management Inc | $455,543.00 | 0.2 | 113,038 | New | +$455,543.00 | 0.07 | |
| Barclays | $358,000.00 | 0.16 | 88,908 | -19.87% | -$88,771.18 | <0.0001 | |
| Fidelity Investments | $315,714.00 | 0.14 | 78,341 | -0.85% | -$2,704.13 | <0.0001 | |
| RhumbLine Advisers | $211,374.00 | 0.09 | 52,452 | +3.12% | +$6,399.41 | <0.0001 | |
| Ameriprise Financial | $203,575.00 | 0.09 | 50,515 | -4.72% | -$10,074.98 | <0.0001 | |
| HSBC | $196,620.00 | 0.09 | 48,789 | +8.29% | +$15,048.05 | <0.0001 | |
| Prelude Capital | $195,858.00 | 0.09 | 48,600 | 0% | +$0 | 0.01 | |
| Prudential Financial | $188,664.00 | 0.08 | 46,815 | +154.22% | +$114,451.73 | <0.0001 | |
| Bank of America | $182,951.00 | 0.08 | 45,397 | -47.42% | -$164,993.21 | <0.0001 | |
| JPMorgan Chase | $155,977.00 | 0.07 | 38,704 | -6.2% | -$10,300.67 | <0.0001 | |
| AllianceBernstein | $151,125.00 | 0.07 | 37,500 | 0% | +$0 | <0.0001 | |
| Dimensional Fund Advisors | $148,526.00 | 0.07 | 36,855 | -11.93% | -$20,121.84 | <0.0001 | |
| Squarepoint Ops LLC | $146,841.00 | 0.06 | 36,437 | -5.18% | -$8,027.75 | <0.01 | |
| UBS | $133,123.00 | 0.06 | 33,033 | -34.51% | -$70,154.24 | <0.0001 | |
| Ohio Strs | $118,000.00 | 0.05 | 29,300 | -59.75% | -$175,187.71 | <0.0001 | |
| Deutsche Bank | $113,219.00 | 0.05 | 28,094 | 0% | +$0 | <0.0001 | |
| Ci Private Wealth Llc | $108,669.00 | 0.05 | 26,965 | New | +$108,669.00 | <0.0001 | |
| Tudor Investment Corp Et Al | $102,068.00 | 0.05 | 25,327 | New | +$102,068.00 | <0.01 |