Iovance Biotherapeutics, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing cancer immunotherapy products to harness the power of a patient's immune system to eradicate cancer cells. It has six ongoing phase 2 clinical studies, including C-144-01, of its lead product candidate, lifileucel, for the treatment of metastatic melanoma; C-145-04, of its product candidate lifileucel for recurrent, metastatic, or persistent cervical cancer; and C-145-03, of its product candidate LN-145, for recurrent and/or metastatic head and neck squamous cell carcinoma. Iovance Biotherapeutics, Inc. has collaborations and licensing agreements with H. Lee Moffitt Cancer Center; M.D. Anderson Cancer Center; Ohio State University; Centre hospitalier de l'Université de Montreal; Cellectis S.A.; and Novartis Pharma AG. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.
Over the last 12 months, insiders at Iovance Biotherapeutics, Inc. have bought $74.89M and sold $0 worth of Iovance Biotherapeutics, Inc. stock.
On average, over the past 5 years, insiders at Iovance Biotherapeutics, Inc. have bought $47.89M and sold $0 worth of stock each year.
Highest buying activity among insiders over the last 12 months: Rothbaum Wayne P. (director) — $72.25M. MCPEAK MERRILL A (director) — $4.69M. Dukes Iain D. (director) — $292,800.
The last purchase of 5,000,000 shares for transaction amount of $45.75M was made by Rothbaum Wayne P. (director) on 2024‑02‑20.
2024-02-20 | Rothbaum Wayne P. | director | 5M 1.4985% | $9.15 | $45.75M | +2.74% | ||
2024-02-20 | MCPEAK MERRILL A | director | 250,000 0.0749% | $9.15 | $2.29M | +2.74% | ||
2024-02-20 | Dukes Iain D. | director | 32,000 0.0096% | $9.15 | $292,800 | +2.74% | ||
2023-09-18 | MCPEAK MERRILL A | director | 10,000 0.0038% | $5.56 | $55,600 | +37.69% | ||
2023-09-15 | Rothbaum Wayne P. | director | 5M 2.0294% | $5.30 | $26.5M | +54.89% | ||
2022-12-21 | MCPEAK MERRILL A | director | 10,000 0.0062% | $6.15 | $61,500 | +5.62% | ||
2022-12-02 | Rothbaum Wayne P. | director | 10M 5.7676% | $6.50 | $65M | -6.58% | ||
2022-11-29 | MCPEAK MERRILL A | director | 10,000 0.0062% | $6.31 | $63,100 | +4.32% | ||
2022-11-28 | MCPEAK MERRILL A | director | 10,000 0.0063% | $6.18 | $61,800 | +7.65% | ||
2022-11-28 | Vogt Frederick G | Interim CEO & General Counsel | 1,000 0.0006% | $5.98 | $5,980 | +7.65% | ||
2022-11-23 | Dukes Iain D. | director | 10,000 0.006% | $6.10 | $61,000 | +3.05% | ||
2022-06-01 | Vogt Frederick G | Interim CEO & General Counsel | 1,000 0.0006% | $6.44 | $6,440 | +22.88% | ||
2022-05-31 | Rothbaum Wayne P. | 500,000 0.3188% | $6.77 | $3.38M | +15.11% | |||
2022-05-31 | WEISER MICHAEL | 2,187 0.0014% | $6.79 | $14,850 | +15.11% | |||
2022-05-31 | MCPEAK MERRILL A | 10,000 0.0064% | $6.84 | $68,400 | +15.11% | |||
2022-05-31 | Maynard Ryan D | 7,500 0.0048% | $6.75 | $50,588 | +15.11% | |||
2018-12-18 | Dukes Iain D. | director | 24,000 0.0202% | $8.65 | $207,593 | +114.64% | ||
2018-12-13 | MCPEAK MERRILL A | director | 20,000 0.0082% | $4.81 | $96,273 | +84.26% | ||
2018-12-06 | Rothbaum Wayne P. | director | 600,000 0.4993% | $9.86 | $5.92M | +82.46% | ||
2018-12-04 | Rothbaum Wayne P. | director | 1.84M 1.6109% | $10.31 | $18.99M | +82.22% |
Rothbaum Wayne P. | director | 28067333 9.0136% | $8.11 | 6 | 0 | +43.3% |
MCPEAK MERRILL A | director | 320150 0.0972% | $8.11 | 9 | 0 | +33.49% |
Dukes Iain D. | director | 54000 0.0086% | $8.11 | 3 | 0 | +58.85% |
BRISTOL INVESTMENT FUND LTD | 10 percent owner | 10023628 3.9167% | $8.11 | 1 | 0 | |
Ayer Capital Management, LP | 10 percent owner | 2823333 1.1032% | $8.11 | 0 | 1 | |
Singh Manish | President & CEO | 1938500 0.7575% | $8.11 | 1 | 0 | +84% |
Schroeder Martin | director | 1000000 0.3908% | $8.11 | 1 | 0 | |
BRISTOL CAPITAL LLC | 10 percent owner | 133532 0.0522% | $8.11 | 0 | 5 | |
WEISER MICHAEL | 104819 0.041% | $8.11 | 1 | 0 | +15.11% | |
Hillsberg Sanford | director | 100000 0.0391% | $8.11 | 0 | 7 | |
Maynard Ryan D | 7500 0.0029% | $8.11 | 1 | 0 | +15.11% | |
Vogt Frederick G | Interim CEO & General Counsel | 2000 0.0008% | $8.11 | 2 | 0 | +15.27% |
The Vanguard Group | $369.24M | 8.9 | 24.92M | +9.22% | +$31.16M | 0.01 | |
MHR Fund Management | $355.64M | 8.58 | 24M | +20% | +$59.28M | 34.36 | |
BlackRock | $295.36M | 7.12 | 19.93M | +4.5% | +$12.71M | 0.01 | |
Perceptive Advisors | $285.63M | 6.89 | 19.27M | +60.88% | +$108.09M | 0.19 | |
Avoro Capital Advisors Llc | $173.39M | 4.18 | 11.7M | +74.63% | +$74.1M | 2.08 | |
State Street | $154.17M | 3.72 | 10.4M | -36.66% | -$89.24M | 0.01 | |
Geode Capital Management | $81.62M | 1.97 | 5.51M | +9.32% | +$6.96M | 0.01 | |
T. Rowe Price | $78.07M | 1.88 | 5.27M | +60.77% | +$29.51M | 0.01 | |
Artisan Partners | $76.15M | 1.84 | 5.14M | +6.43% | +$4.6M | 0.11 | |
JPMorgan Chase | $65M | 1.57 | 4.39M | +54.44% | +$22.91M | 0.01 | |
Goldman Sachs | $56.06M | 1.35 | 3.78M | +2.74% | +$1.5M | 0.01 | |
Soleus Capital Management, L.P. | $51.94M | 1.25 | 3.5M | +531.53% | +$43.72M | 0.5 | |
Voloridge Investment Management, LLC | $51.78M | 1.25 | 3.49M | +255.43% | +$37.21M | 0.12 | |
Summit Partners Public Asset Management LLC | $43.96M | 1.06 | 2.97M | New | +$43.96M | 2.12 | |
Dimensional Fund Advisors | $42.56M | 1.03 | 2.87M | -18.35% | -$9.57M | 0.01 | |
Morgan Stanley | $39.88M | 0.96 | 2.69M | -27.57% | -$15.18M | <0.01 | |
Hood River Capital Management LLC | $38.89M | 0.94 | 2.62M | +31.11% | +$9.23M | 0.87 | |
D. E. Shaw & Co. | $34.86M | 0.84 | 2.35M | +993.35% | +$31.67M | 0.05 | |
Northern Trust | $33.01M | 0.8 | 2.23M | +2.04% | +$659,000.94 | 0.01 | |
Bioimpact Capital Llc | $32.6M | 0.79 | 2.2M | -33.12% | -$16.15M | 5.28 | |
Palo Alto Investors Lp | $31.31M | 0.76 | 2.11M | +0.29% | +$89,201.58 | 3.53 | |
Credit Suisse | $29.76M | 0.72 | 2.01M | -28.65% | -$11.95M | 0.03 | |
Charles Schwab | $28.35M | 0.68 | 1.91M | +9.51% | +$2.46M | 0.01 | |
Susquehanna International Group | $26.93M | 0.65 | 1.82M | +13.64% | +$3.23M | 0.03 | |
Rice Hall James & Associates, LLC | $25.4M | 0.61 | 1.71M | -2.12% | -$549,555.25 | 1.54 | |
Nuveen | $24.52M | 0.59 | 1.65M | +74.93% | +$10.5M | 0.01 | |
Millennium Management LLC | $23.96M | 0.58 | 1.62M | +72.09% | +$10.04M | 0.02 | |
Bank of America | $22.71M | 0.55 | 1.53M | +63.55% | +$8.82M | <0.01 | |
Woodline Partners LP | $21.98M | 0.53 | 1.48M | -7.59% | -$1.81M | 0.21 | |
Long Focus Capital Management Llc | $20.75M | 0.5 | 1.4M | -34.43% | -$10.9M | 2.41 | |
T Rowe Price Investment Management Inc | $19.46M | 0.47 | 1.31M | New | +$19.46M | 0.01 | |
683 Capital Management Llc | $18.15M | 0.44 | 1.23M | -30% | -$7.78M | 2.04 | |
Balyasny Asset Management Llc | $17.8M | 0.43 | 1.2M | -69.41% | -$40.39M | 0.05 | |
New York State Common Retirement Fund | $17.26M | 0.42 | 1.16M | +13.99% | +$2.12M | 0.02 | |
Citadel Advisors LLC | $16.46M | 0.4 | 1.11M | +288.41% | +$12.23M | 0.01 | |
C Worldwide Group Holding A S | $15.71M | 0.38 | 1.06M | -22.06% | -$4.45M | 0.18 | |
Candriam S C A | $15.7M | 0.38 | 1.06M | -38.7% | -$9.91M | 0.1 | |
Jane Street Capital | $15.13M | 0.37 | 1.02M | +95.4% | +$7.39M | 0.02 | |
RHENMAN & PARTNERS ASSET MANAGEMENT AB | $14.15M | 0.34 | 955,000 | -14.49% | -$2.4M | 1.35 | |
Opaleye Management Inc | $13.29M | 0.32 | 897,000 | 0% | +$0 | 2.1 | |
BNY Mellon | $12.36M | 0.3 | 834,224 | -1.88% | -$236,838.54 | <0.01 | |
Boxer Capital, LLC | $11.12M | 0.27 | 750,000 | -46.43% | -$9.63M | 0.56 | |
Deutsche Bank | $10.72M | 0.26 | 723,666 | -62.22% | -$17.66M | 0.01 | |
UBS | $10.24M | 0.25 | 690,880 | -19.41% | -$2.47M | <0.01 | |
Banque Pictet Cie Sa | $10.22M | 0.25 | 689,356 | -11.4% | -$1.31M | 0.11 | |
QVT Financial | $10.1M | 0.24 | 678,564 | 0% | +$0 | 1.01 | |
Braidwell Lp | $9.78M | 0.24 | 660,022 | New | +$9.78M | 0.55 | |
Driehaus Capital Management LLC | $9.53M | 0.23 | 642,761 | New | +$9.53M | 0.1 | |
Rafferty Asset Management Llc | $8.66M | 0.21 | 584,111 | -53.18% | -$9.83M | 0.03 | |
HERITAGE ASSET MANAGEMENT INC | $7.82M | 0.2 | 551,018 | +22.32% | +$1.43M | 0.04 |