| Aadi Bioscience, Inc. AADI | $6.67M | 11.61 | 2.85M | 0% | +$0 | 0.08 | |
| Taysha Gene Therapies, Inc. TSHA | $53.53M | 9.97 | 18.65M | +328.19% | +$41.03M | 0.64 | |
| MacroGenics, Inc. MGNX | $90.53M | 9.82 | 6.15M | New | +$90.53M | 1.09 | |
| Vera Therapeutics, Inc. VERA | $227.03M | 9.63 | 5.26M | New | +$227.03M | 2.72 | |
| Verrica Pharmaceuticals Inc. VRCA | $23.68M | 9.43 | 4M | 0% | +$0 | 0.28 | |
| Amicus Therapeutics, Inc. FOLD | $322.77M | 9.25 | 27.4M | 0% | +$0 | 3.87 | |
| Apellis Pharmaceuticals, Inc. APLS | $653.11M | 9.15 | 11.11M | 0% | +$0 | 7.83 | |
| Madrigal Pharmaceuticals, Inc. MDGL | $519.24M | 9.12 | 1.94M | +2.94% | +$14.84M | 6.22 | |
| Krystal Biotech, Inc. KRYS | $454.71M | 8.95 | 2.56M | -0.39% | -$1.78M | 5.45 | |
Tourmaline Bio, Inc. TRML | $50.89M | 8.66 | 2.22M | +155.9% | +$31M | 0.61 | |
| Marinus Pharmaceuticals, Inc. MRNS | $37.43M | 7.54 | 4.14M | +31.45% | +$8.96M | 0.45 | |
| Xenon Pharmaceuticals Inc. XENE | $243.95M | 7.51 | 5.67M | 0% | +$0 | 2.92 | |
| Monte Rosa Therapeutics, Inc. GLUE | $31.97M | 7.45 | 4.54M | 0% | +$0 | 0.38 | |
| Arrowhead Pharmaceuticals, Inc. ARWR | $244.69M | 6.89 | 8.56M | +657.13% | +$212.37M | 2.93 | |
Ascendis Pharma A/S ASND | $599.64M | 6.81 | 3.97M | +5.62% | +$31.91M | 7.19 | |
| United Therapeutics Corporation UTHR | $656.74M | 6.45 | 2.86M | 0% | +$0 | 7.87 | |
| Kymera Therapeutics, Inc. KYMR | $156.33M | 6.34 | 3.89M | +3.02% | +$4.58M | 1.87 | |
| BioCryst Pharmaceuticals, Inc. BCRX | $66.29M | 6.32 | 13.05M | 0% | +$0 | 0.79 | |
Avidity Biosciences, Inc. RNA | $148.65M | 6.09 | 5.83M | +132.07% | +$84.6M | 1.78 | |
| Kura Oncology, Inc. KURA | $82.12M | 5.05 | 3.85M | +29.2% | +$18.56M | 0.98 | |
| Syndax Pharmaceuticals, Inc. SNDX | $100.49M | 4.97 | 4.22M | 0% | +$0 | 1.2 | |
| Soleno Therapeutics, Inc. SLNO | $69.55M | 4.69 | 1.63M | +107.01% | +$35.95M | 0.83 | |
Autolus Therapeutics plc AUTL | $78.77M | 4.64 | 12.35M | New | +$78.77M | 0.94 | |
| Ocular Therapeutix, Inc. OCUL | $65.06M | 4.62 | 7.15M | New | +$65.06M | 0.78 | |
| Sarepta Therapeutics, Inc. SRPT | $562.43M | 4.6 | 4.34M | 0% | +$0 | 6.74 | |
Spyre Therapeutics, Inc. SYRE | $69.76M | 4.57 | 1.84M | 0% | +$0 | 0.84 | |
| Iovance Biotherapeutics, Inc. IOVA | $173.39M | 4.18 | 11.7M | +74.63% | +$74.1M | 2.08 | |
Cerevel Therapeutics Holdings, Inc. CERE | $319.37M | 4.15 | 7.56M | 0% | +$0 | 3.83 | |
MoonLake Immunotherapeutics MLTX | $129.59M | 4.04 | 2.58M | 0% | +$0 | 1.55 | |
| MannKind Corporation MNKD | $40.77M | 3.31 | 9M | 0% | +$0 | 0.49 | |
| Viking Therapeutics, Inc. VKTX | $294.38M | 3.26 | 3.59M | New | +$294.38M | 3.53 | |
| Intra-Cellular Therapies, Inc. ITCI | $171.27M | 2.34 | 2.48M | +9.73% | +$15.19M | 2.05 | |
| BioMarin Pharmaceutical Inc. BMRN | $381.24M | 2.3 | 4.37M | +1.51% | +$5.68M | 4.57 | |
argenx SE ARGX | $487.61M | 2.08 | 1.24M | +0.32% | +$1.54M | 5.84 | |
| Adverum Biotechnologies, Inc. ADVM | $5.89M | 2.01 | 416,666 | New | +$5.89M | 0.07 | |
| Merus N.V. MRUS | $40.03M | 1.52 | 888,888 | 0% | +$0 | 0.48 | |
| Rocket Pharmaceuticals, Inc. RCKT | $33.97M | 1.39 | 1.26M | 0% | +$0 | 0.41 | |
Kyverna Therapeutics, Inc. Common Stock KYTX | $11.8M | 1.1 | 475,000 | New | +$11.8M | 0.14 | |
CG Oncology, Inc. Common stock CGON | $30.73M | 1.05 | 700,000 | New | +$30.73M | 0.37 | |
| Ultragenyx Pharmaceutical Inc. RARE | $38.75M | 1 | 830,000 | +137.14% | +$22.41M | 0.46 | |
| Roivant Sciences Ltd. ROIV | $49.02M | 0.58 | 4.65M | 0% | +$0 | 0.59 | |
| Vaxcyte, Inc. PCVX | $39.28M | 0.53 | 575,000 | New | +$39.28M | 0.47 | |
| CRISPR Therapeutics AG CRSP | $28.6M | 0.49 | 419,580 | New | +$28.6M | 0.34 | |
| Alnylam Pharmaceuticals, Inc. ALNY | $44.84M | 0.24 | 300,000 | -73% | -$121.22M | 0.54 | |
SPDR S&P Biotech ETF XBI | $408.03M | <0.01 | 4.3M | -3.25% | -$13.71M | 4.89 |