Taysha Gene Therapies, Inc. (TSHA)
Largest Insider Buys in Sector
TSHA Stock Price History Chart
TSHA Stock Performance
About Taysha Gene Therapies, Inc.
Taysha Gene Therapies, Inc., a gene therapy company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN1 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 foe the treatment of for SLC13A5 Deficiency; and TSHA-101 for the treatment of GM2 gangliosidosis. Taysha Gene Therapies, Inc. has a strategic partnership with The University of Texas Southwestern Medical Center to develop and commercialize transformative gene therapy treatments. The company was incorporated in 2019 and is based in Dallas, Texas.
Insider Activity of Taysha Gene Therapies, Inc.
Over the last 12 months, insiders at Taysha Gene Therapies, Inc. have bought $16.18M and sold $137,661 worth of Taysha Gene Therapies, Inc. stock.
On average, over the past 5 years, insiders at Taysha Gene Therapies, Inc. have bought $5.49M and sold $975,279 worth of stock each year.
Highest buying activity among insiders over the last 12 months: Manning Paul B (10 percent owner) — $74.92M. Stalfort John A III (director) — $2.1M. Nolan Sean P. (Chief Executive Officer) — $400,000.
The last purchase of 100,000 shares for transaction amount of $163,000 was made by Manning Paul B (10 percent owner) on 2023‑11‑17.
List of Insider Buy and Sell Transactions, Taysha Gene Therapies, Inc.
| 2023-11-17 | Manning Paul B | 10 percent owner | 100,000 0.0519% | $1.63 | $163,000 | +42.52% | ||
| 2023-08-24 | Sale | Alam Kamran | Chief Financial Officer | 33,000 0.0537% | $2.33 | $76,890 | +3.63% | |
| 2023-08-16 | Manning Paul B | 10 percent owner | 16.47M 11.9647% | $0.90 | $14.82M | +24.35% | ||
| 2023-08-16 | Nolan Sean P. | Chief Executive Officer | 444,444 0.3229% | $0.90 | $400,000 | +24.35% | ||
| 2023-08-16 | Stalfort John A III | director | 777,778 0.5651% | $0.90 | $700,000 | +24.35% | ||
| 2023-08-16 | Donenberg Phillip B. | director | 111,111 0.0807% | $0.90 | $100,000 | +24.35% | ||
| 2023-07-13 | Sale | Session R.A. II | 10 percent owner | 5,344 0.0084% | $0.70 | $3,741 | +233.57% | |
| 2023-07-12 | Sale | Session R.A. II | 10 percent owner | 80,528 0.1263% | $0.71 | $57,030 | +226.33% | |
| 2023-06-23 | Sale | Session R.A. II | 10 percent owner | 18,100 0.0305% | $0.70 | $12,735 | +242.42% | |
| 2023-06-22 | Sale | Session R.A. II | 10 percent owner | 10,508 0.0163% | $0.70 | $7,384 | +214.94% | |
| 2023-06-21 | Sale | Session R.A. II | 10 percent owner | 138,962 0.2204% | $0.70 | $97,635 | +221.43% | |
| 2023-06-20 | Sale | Session R.A. II | 10 percent owner | 295,653 0.4778% | $0.71 | $210,209 | +223.74% | |
| 2023-05-16 | Nagendran Sukumar | President and Head of R&D | 5,000 0.0078% | $0.68 | $3,400 | +173.12% | ||
| 2022-10-31 | Manning Paul B | director | 1.5M 3.9684% | $2.00 | $3M | -34.88% | ||
| 2022-08-23 | Sale | Alam Kamran | Chief Financial Officer | 3,325 0.0081% | $3.47 | $11,538 | -67.72% | |
| 2022-08-18 | Sale | Alam Kamran | Chief Financial Officer | 11,482 0.0271% | $3.75 | $43,058 | -71.13% | |
| 2022-07-05 | Sale | PRASAD SUYASH | CMO and Head of R&D | 3,905 0.0095% | $3.51 | $13,707 | -48.86% | |
| 2022-06-29 | Sale | PRASAD SUYASH | CMO and Head of R&D | 12,324 0.0304% | $3.81 | $46,954 | -51.95% | |
| 2022-02-03 | Manning Paul B | 76,602 0.2022% | $7.84 | $600,560 | -59.00% | |||
| 2022-02-02 | Manning Paul B | 125,000 0.3321% | $7.77 | $971,250 | -57.83% |
Insider Historical Profitability
| Manning Paul B | 10 percent owner | 16566667 8.8611% | $2.04 | 8 | 0 | <0.0001% |
| Session R.A. II | 10 percent owner | 8871747 4.7453% | $2.04 | 1 | 6 | <0.0001% |
| Nolan Sean P. | Chief Executive Officer | 1535545 0.8213% | $2.04 | 2 | 0 | <0.0001% |
| Stalfort John A III | director | 999381 0.5345% | $2.04 | 1 | 0 | |
| Alam Kamran | Chief Financial Officer | 258042 0.138% | $2.04 | 0 | 6 | |
| Donenberg Phillip B. | director | 114111 0.061% | $2.04 | 2 | 0 | <0.0001% |
| PRASAD SUYASH | CMO and Head of R&D | 539545 0.2886% | $2.04 | 0 | 5 | |
| Nagendran Sukumar | President and Head of R&D | 34226 0.0183% | $2.04 | 2 | 0 | +57.64% |
Institutional Investor Ownership
| Fidelity Investments | $57.72M | 10.75 | 20.11M | -10.38% | -$6.68M | <0.01 | |
| Avoro Capital Advisors Llc | $53.53M | 9.97 | 18.65M | +328.19% | +$41.03M | 0.64 | |
| RTW Investments, LP | $53.36M | 9.94 | 18.59M | +10.06% | +$4.88M | 0.79 | |
| RA Capital Management, L.P. | $31.2M | 5.81 | 10.87M | -41.14% | -$21.81M | 0.03 | |
| Vr Adviser Llc | $25.83M | 4.81 | 9M | -13.57% | -$4.05M | 1.26 | |
| The Vanguard Group | $16.98M | 3.16 | 5.92M | -4.49% | -$798,299.10 | <0.0001 | |
| Morgan Stanley | $14.83M | 2.76 | 5.17M | +2,287.06% | +$14.21M | <0.01 | |
| Baker Bros Advisors LP | $11.49M | 2.14 | 4M | 0% | +$0 | 0.14 | |
| Tybourne Capital Management HK Ltd | $10.62M | 1.98 | 3.7M | 0% | +$0 | 1.82 | |
| Artal Group S A | $10.58M | 1.97 | 3.69M | +0.67% | +$70,154.28 | 0.06 | |
| ACUTA CAPITAL PARTNERS LLC | $9.57M | 1.78 | 3.33M | -7.13% | -$734,720.02 | 6.22 | |
| Millennium Management LLC | $9M | 1.68 | 3.14M | -7.25% | -$703,767.07 | 0.01 | |
| Octagon Capital Advisors LP | $8.7M | 1.62 | 3.03M | New | +$8.7M | 1.14 | |
| BlackRock | $7.45M | 1.39 | 2.6M | -3.78% | -$292,553.47 | <0.0001 | |
| Polar Capital | $7.23M | 1.35 | 2.52M | 0% | +$0 | 0.04 | |
| Eversept Partners LP | $6.67M | 1.24 | 2.33M | -38.49% | -$4.18M | 0.5 | |
| HERITAGE ASSET MANAGEMENT INC | $5.08M | 0.96 | 1.79M | New | +$5.08M | 0.03 | |
| Cowen Group | $4.45M | 0.83 | 1.55M | New | +$4.45M | 0.14 | |
| Susquehanna International Group | $3.76M | 0.7 | 1.31M | -8.3% | -$340,149.58 | <0.01 | |
| Point72 Asset Management | $3.19M | 0.6 | 1.11M | -58.59% | -$4.52M | 0.01 | |
| T. Rowe Price | $3.16M | 0.59 | 1.1M | -10.43% | -$367,479.28 | <0.0001 | |
| Qube Research & Technologies | $3.08M | 0.57 | 1.07M | +804.54% | +$2.74M | <0.01 | |
| Goldman Sachs | $3.04M | 0.57 | 1.06M | +1,168.61% | +$2.8M | <0.01 | |
| Marshall Wace | $2.96M | 0.55 | 1.03M | New | +$2.96M | <0.01 | |
| Geode Capital Management | $2.93M | 0.55 | 1.02M | +3.49% | +$98,671.25 | <0.0001 | |
| GHOST TREE CAPITAL LLC | $2.73M | 0.51 | 950,000 | -54.76% | -$3.3M | 0.89 | |
| Soleus Capital Management, L.P. | $2.65M | 0.5 | 925,000 | New | +$2.65M | 0.03 | |
| Palo Alto Investors Lp | $2.33M | 0.43 | 811,268 | +53.11% | +$807,638.03 | 0.26 | |
| Sands Capital Ventures LLC | $2.08M | 0.39 | 724,873 | 0% | +$0 | 0.5 | |
| Quantum Private Wealth Llc | $2M | 0.37 | 698,520 | +9.23% | +$169,330.05 | 0.77 | |
| Alphabet | $1.84M | 0.34 | 640,882 | 0% | +$0 | 0.07 | |
| Schonfeld Group | $1.59M | 0.3 | 552,595 | -50.63% | -$1.63M | 0.01 | |
| Hrt Financial Llc | $1.19M | 0.22 | 414,980 | New | +$1.19M | 0.01 | |
| State Street | $974,422.00 | 0.18 | 339,520 | +137.06% | +$563,380.77 | <0.0001 | |
| Renaissance Technologies | $943,000.00 | 0.18 | 328,500 | -70.07% | -$2.21M | <0.01 | |
| Kovitz | $797,223.00 | 0.15 | 277,778 | 0% | +$0 | 0.01 | |
| Citigroup | $732,433.00 | 0.14 | 255,203 | -17.93% | -$160,031.29 | <0.01 | |
| Marathon Trading Investment Management Llc | $642,593.00 | 0.12 | 223,900 | New | +$642,593.00 | 0.25 | |
| Adage Capital Partners Gp L L C | $631,400.00 | 0.12 | 220,000 | -47.62% | -$574,000.00 | <0.01 | |
| Squarepoint Ops LLC | $614,025.00 | 0.11 | 213,946 | +237.04% | +$431,846.02 | <0.01 | |
| Northern Trust | $606,704.00 | 0.11 | 211,395 | -1.09% | -$6,675.62 | <0.0001 | |
| Balyasny Asset Management Llc | $541,563.00 | 0.1 | 188,698 | New | +$541,563.00 | <0.01 | |
| UBS | $543,245.00 | 0.1 | 189,284 | +4,700.51% | +$531,928.59 | <0.0001 | |
| Point72 Asia Singapore Pte Ltd | $520,348.00 | 0.1 | 181,306 | New | +$520,348.00 | 0.05 | |
| Td Asset Management Inc | $503,972.00 | 0.09 | 175,600 | 0% | +$0 | <0.0001 | |
| Brevan Howard Capital Management Lp | $495,847.00 | 0.09 | 172,769 | New | +$495,847.00 | 0.04 | |
| Laurion Capital Management LP | $471,420.00 | 0.09 | 164,258 | New | +$471,420.00 | 0.01 | |
| Cubist Systematic Strategies | $462,357.00 | 0.09 | 161,100 | +232.62% | +$323,351.42 | <0.01 | |
| Diametric Capital Lp | $440,481.00 | 0.08 | 153,478 | +122.85% | +$242,821.62 | 0.18 | |
| Bank of America | $360,797.00 | 0.07 | 125,713 | +2.77% | +$9,714.97 | <0.0001 |