| $385M | ||
| $350M | ||
| $215M | ||
| $82M | ||
| $76M | ||
| $62M |
Buys | $150,515 | 2 | 100 |
Sells | $0 | 0 | 0 |
| HEIDEN WILLIAM K | director | 2 | $150,515 | 0 | $0 | $150,515 |
MacroGenics, Inc., a biopharmaceutical company, develops and commercializes antibody-based therapeutics to treat cancer in the United States. Its approved product is MARGENZA (margetuximab-cmkb), a human epidermal growth factor receptor 2 (HER2) receptor antagonist indicated, in combination with chemotherapy, for the treatment of adult patients with metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 regimens. The company's pipeline of immuno-oncology product candidates includes MGC018, an antibody drug conjugate (ADC), which targets solid tumors expressing B7-H3; Enoblituzumab, a monoclonal antibody that targets B7-H3; and MGD024, an investigational bispecific CD123 × CD3 DART molecule to minimize cytokine-release syndrome for patients with hematologic malignancies. It also develops Lorigerlimab, a monoclonal antibody that targets the immune checkpoints PD-1 and cytotoxic T-lymphocyte-associated protein 4; Tebotelimab, an investigational tetravalent DART molecule for PD-1 and lymphocyte-activation gene 3; Retifanlimab, an investigational monoclonal antibody targeting metastatic squamous cell carcinoma of the anal canal and metastatic non-small cell lung cancer; and IMGC936, an ADC that targets ADAM9, a cell surface protein over-expressed in various solid tumor types. Further, the company develops MGD014 and MGD020, a DART molecule to target the envelope protein of human immunodeficiency virus infected cells and CD3 on T cells; Teplizumab for the treatment of type 1 diabetes; and PRV-3279, a CD32B × CD79B DART molecule for the treatment of autoimmune indications. It has collaborations with Incyte Corporation; Zai Lab Limited; I-Mab Biopharma; and Janssen Biotech, Inc. The company was incorporated in 2000 and is headquartered in Rockville, Maryland.
Over the last 12 months, insiders at MacroGenics, Inc. have bought $150,515 and sold $0 worth of MacroGenics, Inc. stock.
On average, over the past 5 years, insiders at MacroGenics, Inc. have bought $9.73M and sold $1.48M worth of stock each year.
Highest buying activity among insiders over the last 12 months: HEIDEN WILLIAM K (director) — $150,515.
The last purchase of 49,500 shares for transaction amount of $73,755 was made by HEIDEN WILLIAM K (director) on 2025‑08‑20.
| 2025-08-20 | HEIDEN WILLIAM K | director | 49,500 0.0783% | $1.49 | $73,755 | +14.23% | ||
| 2025-08-19 | HEIDEN WILLIAM K | director | 50,500 0.0815% | $1.52 | $76,760 | +14.09% | ||
| 2025-02-15 | Sale | Smith Beth Ann | VP, Controller & Treasurer | 423 0.0007% | $2.56 | $1,083 | +0.54% | |
| 2024-04-04 | Sale | Peters Jeffrey Stuart | Senior VP and General Counsel | 51,395 0.0725% | $15.55 | $799,148 | -80.20% | |
| 2024-03-06 | Sale | Peters Jeffrey Stuart | Senior VP and General Counsel | 19,625 0.0317% | $21.50 | $421,938 | -82.98% | |
| 2024-03-04 | Sale | Karrels James | SVP, CFO and Secretary | 30,000 0.0481% | $20.50 | $615,000 | -82.17% | |
| 2024-03-04 | Sale | Risser Eric Blasius | Chief Operating Officer | 41,159 0.0636% | $19.76 | $813,501 | -82.17% | |
| 2024-03-04 | Sale | Spitznagel Thomas | Sr VP, Technical Ops | 10,000 0.0156% | $20.00 | $200,000 | -82.17% | |
| 2024-02-26 | Sale | Peters Jeffrey Stuart | Senior VP and General Counsel | 16,124 0.0266% | $17.22 | $277,655 | -77.57% | |
| 2024-02-07 | Sale | Bonvini Ezio | Sr VP, Research & CSO | 3,334 0.0069% | $18.00 | $60,012 | -76.65% | |
| 2024-02-05 | Sale | Peters Jeffrey Stuart | Senior VP and General Counsel | 76,251 0.1454% | $16.50 | $1.26M | -75.52% | |
| 2024-02-01 | Sale | Bonvini Ezio | Sr VP, Research & CSO | 13,316 0.0231% | $15.00 | $199,740 | -73.02% | |
| 2024-01-19 | Sale | Bonvini Ezio | Sr VP, Research & CSO | 13,316 0.0216% | $12.00 | $159,792 | -64.71% | |
| 2023-12-20 | Sale | Bonvini Ezio | Sr VP, Research & CSO | 18,880 0.031% | $10.08 | $190,310 | -54.68% | |
| 2023-10-02 | BIOTECH TARGET N V | 10 percent owner | 150,000 0.2413% | $4.46 | $669,585 | +42.19% | ||
| 2023-09-07 | BIOTECH TARGET N V | 10 percent owner | 200,000 0.324% | $5.26 | $1.05M | +20.64% | ||
| 2023-08-30 | HURWITZ EDWARD | director | 15,000 0.0244% | $4.91 | $73,650 | +30.00% | ||
| 2023-03-10 | Sale | Peters Jeffrey Stuart | Senior VP and General Counsel | 5,372 0.0099% | $6.03 | $32,393 | +19.64% | |
| 2023-02-14 | BIOTECH TARGET N V | 10 percent owner | 500,000 0.7819% | $5.07 | $2.53M | +15.84% | ||
| 2023-01-19 | BIOTECH TARGET N V | director | 150,000 0.245% | $5.30 | $794,925 | +10.10% |
| HEIDEN WILLIAM K | director | 111000 0.1755% | $380,730.00 | 2 | 0 | |
| BIOTECH TARGET N V | 10 percent owner | 9929963 15.6974% | $34.06M | 19 | 0 | <0.0001% |
| ORONSKY ARNOLD L | director | 1708716 2.7012% | $5.86M | 0 | 1 | |
| Karrels James | SVP, CFO and Secretary | 171452 0.271% | $588,080.36 | 1 | 3 | +137.87% |
| Bonvini Ezio | Sr VP, Research & CSO | 71334 0.1128% | $244,675.62 | 0 | 16 | |
| Costa Paulo F | director | 59435 0.094% | $203,862.05 | 1 | 0 | +41.83% |
| Stein Kathryn E | SVP, Product Dev. & Regulatory | 43205 0.0683% | $148,193.15 | 0 | 6 | |
| Risser Eric Blasius | Chief Operating Officer | 38900 0.0615% | $133,427.00 | 0 | 26 | |
| HURWITZ EDWARD | director | 33074 0.0523% | $113,443.82 | 1 | 1 | |
| Wigginton Jon Marc | Sr VP, Clinical Dev. & CMO | 30000 0.0474% | $102,900.00 | 0 | 17 | |
| Smith Beth Ann | VP, Controller & Treasurer | 9532 0.0151% | $32,694.76 | 0 | 1 | |
| Spitznagel Thomas | Sr VP, Technical Ops | 8316 0.0131% | $28,523.88 | 0 | 6 | |
| Cilinski Lynn | VP, Controller and Treasurer | 1923 0.003% | $6,595.89 | 0 | 7 | |
| Fust Matthew K | director | 500 0.0008% | $1,715.00 | 0 | 1 | |
| Galbraith Kenneth | director | 0 0% | $0 | 1 | 1 | <0.0001% |
| Peters Jeffrey Stuart | Senior VP and General Counsel | 0 0% | $0 | 0 | 8 |
$22,693,451 | 105 | 8.15% | $197.29M | |
$18,752,549 | 33 | -28.39% | $204.02M | |
$167,701,902 | 27 | -3.07% | $198.66M | |
$6,915,275 | 21 | -32.61% | $220.34M | |
MacroGenics, Inc. (MGNX) | $38,821,584 | 20 | -2.17% | $216.98M |
$135,812,721 | 14 | 17.52% | $221.09M | |
$13,259,565 | 14 | -30.38% | $222.33M | |
$4,701,608 | 14 | -4.34% | $233.22M | |
$1,037,470 | 13 | 78.00% | $216.52M | |
$5,905,507 | 7 | 2.69% | $226.5M | |
$99,355,998 | 7 | -65.74% | $203.53M | |
$8,286,963 | 6 | 3.09% | $217.37M | |
$299,343 | 6 | -44.75% | $189.74M | |
$272,982 | 6 | -28.53% | $227.84M | |
$20,729,984 | 5 | 51.71% | $216.49M | |
$556,839 | 5 | 13.42% | $231.25M | |
$193,101 | 3 | -25.20% | $203.37M | |
$16,003,671 | 3 | 55.38% | $228.43M | |
$12,750 | 2 | -39.73% | $191.15M |
| Increased Positions | 42 | +32.81% | 11M | +24.7% |
| Decreased Positions | 53 | -41.41% | 18M | -38.26% |
| New Positions | 13 | New | 4M | New |
| Sold Out Positions | 24 | Sold Out | 14M | Sold Out |
| Total Postitions | 117 | -8.59% | 40M | -13.56% |
| Bellevue Group Ag | $15,971.00 | 15.75% | 9.92M | 0 | 0% | 2025-09-30 |
| Armistice Capital, Llc | $9,596.00 | 9.46% | 5.96M | 0 | 0% | 2025-09-30 |
| Vanguard Group Inc | $6,801.00 | 6.71% | 4.22M | +11,120 | +0.26% | 2025-09-30 |
| Frazier Life Sciences Management, L.P. | $5,113.00 | 5.04% | 3.18M | 0 | 0% | 2025-09-30 |
| Acadian Asset Management Llc | $4,053.00 | 4% | 2.52M | +25,844 | +1.04% | 2025-09-30 |
| Millennium Management Llc | $3,408.00 | 3.36% | 2.12M | +101,006 | +5.01% | 2025-09-30 |
| Wasatch Advisors Lp | $3,140.00 | 3.1% | 1.95M | -1M | -40.01% | 2025-09-30 |
| Renaissance Technologies Llc | $2,739.00 | 2.7% | 1.7M | +374,729 | +28.25% | 2025-09-30 |
| Blackrock, Inc. | $2,477.00 | 2.44% | 1.54M | -278,835 | -15.34% | 2025-09-30 |
| Morgan Stanley | $1,593.00 | 1.57% | 989,233 | +543,011 | +121.69% | 2025-09-30 |