Lyra Therapeutics, Inc. (LYRA)
NASDAQ
Market Cap
$16.28M
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
292 of 809
Rank in Industry
170 of 445
Largest Insider Buys in Sector
LYRA Stock Price History Chart
LYRA Stock Performance
About Lyra Therapeutics, Inc.
Lyra Therapeutics, Inc., a clinical-stage therapeutics company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. It's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix for the treatment of chronic rhinosinusitis (CRS), which is in Phase II clinical trial; and LYR-220 for CRS patients with and without nasal polyps. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.
Insider Activity of Lyra Therapeutics, Inc.
Over the last 12 months, insiders at Lyra Therapeutics, Inc. have bought $74,095 and sold $0 worth of Lyra Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Lyra Therapeutics, Inc. have bought $17.31M and sold $2.24M worth of stock each year.
Highest buying activity among insiders over the last 12 months: Waksal Harlan (Executive Chair) — $74,095.
The last purchase of 25,000 shares for transaction amount of $74,095 was made by Waksal Harlan (Executive Chair) on 2023‑11‑10.
List of Insider Buy and Sell Transactions, Lyra Therapeutics, Inc.
| 2023-11-10 | Waksal Harlan | Executive Chair | 25,000 0.0498% | $2.96 | $74,095 | +63.04% | ||
| 2023-05-31 | PERCEPTIVE ADVISORS LLC | 3.61M 9.5077% | $2.49 | $9M | +49.03% | |||
| 2023-05-31 | NBVM GP, LLC | 10 percent owner | 1.81M 4.6346% | $2.43 | $4.39M | +49.03% | ||
| 2023-05-31 | NBVM GP, LLC | 10 percent owner | 1.2M 3.0898% | $2.43 | $2.92M | +49.03% | ||
| 2023-05-31 | ANDERSON EDWARD T | 1.81M 4.6346% | $2.43 | $4.39M | +49.03% | |||
| 2022-06-10 | MERRIFIELD C ANN | 4,000 0.0119% | $5.05 | $20,200 | -35.30% | |||
| 2022-05-13 | MERRIFIELD C ANN | 328 0.001% | $5.00 | $1,640 | -19.36% | |||
| 2022-04-12 | EDELMAN JOSEPH | 5.92M 11.8975% | $4.22 | $25M | -21.89% | |||
| 2022-04-12 | ANDERSON EDWARD T | 1.08M 2.1626% | $4.22 | $4.54M | -21.89% | |||
| 2022-04-12 | North Bridge Venture Management VI, L.P. | 765,010 1.5364% | $4.22 | $3.23M | -21.89% | |||
| 2022-04-12 | Waksal Harlan | Executive Chair | 236,966 0.4759% | $4.22 | $999,997 | -21.89% | ||
| 2021-06-17 | MERRIFIELD C ANN | director | 3,500 0.0267% | $8.97 | $31,395 | -36.57% | ||
| 2020-12-16 | snyderman nancy lynn MD | director | 1,025 0.0118% | $9.72 | $9,963 | -14.25% | ||
| 2020-05-05 | Sale | Soleus Private Equity GP I, LLC | 10 percent owner | 33,818 0.3972% | $16.00 | $541,088 | -28.92% | |
| 2020-05-05 | Sale | NBVM GP, LLC | 10 percent owner | 48,366 0.568% | $16.00 | $773,856 | -28.92% | |
| 2020-05-05 | Sale | ANDERSON EDWARD T | 48,366 0.568% | $16.00 | $773,856 | -28.92% | ||
| 2020-05-05 | Sale | Polaris Venture Management Co. V, L.L.C. | 10 percent owner | 9,674 0.1136% | $16.00 | $154,784 | -28.92% | |
| 2020-05-05 | PERCEPTIVE ADVISORS LLC | 1.25M 7.3399% | $8.00 | $10M | -28.92% | |||
| 2020-05-05 | Polaris Venture Management Co. V, L.L.C. | 10 percent owner | 62,500 0.734% | $16.00 | $1M | -28.92% | ||
| 2020-05-05 | NBVM GP, LLC | 10 percent owner | 500,000 5.8719% | $16.00 | $8M | -28.92% |
Insider Historical Profitability
<0.0001%
| Waksal Harlan | Executive Chair | 261966 0.4984% | $0.27 | 2 | 0 | <0.0001% |
| PERCEPTIVE ADVISORS LLC | 11469117 21.8197% | $0.27 | 2 | 0 | +10.05% | |
| EDELMAN JOSEPH | 7858285 14.9502% | $0.27 | 1 | 0 | <0.0001% | |
| NBVM GP, LLC | 10 percent owner | 2521745 4.7976% | $0.27 | 3 | 1 | +23.05% |
| ANDERSON EDWARD T | 2521745 4.7976% | $0.27 | 3 | 1 | <0.0001% | |
| North Bridge Venture Management VI, L.P. | 1318133 2.5077% | $0.27 | 1 | 0 | <0.0001% | |
| Polaris Venture Management Co. V, L.L.C. | 10 percent owner | 1062259 2.0209% | $0.27 | 1 | 1 | <0.0001% |
| Soleus Private Equity GP I, LLC | 10 percent owner | 155000 0.2949% | $0.27 | 1 | 1 | <0.0001% |
| MERRIFIELD C ANN | 11328 0.0216% | $0.27 | 3 | 0 | <0.0001% | |
| snyderman nancy lynn MD | director | 1025 0.002% | $0.27 | 1 | 0 | <0.0001% |
Institutional Investor Ownership
Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
| Perceptive Advisors | $79.35M | 20.93 | 12.76M | 0% | +$0 | 0.05 | |
| Citadel Advisors LLC | $26.99M | 7.12 | 4.34M | +51.65% | +$9.19M | 0.02 | |
| Nantahala Capital Management Llc | $17.55M | 4.63 | 2.82M | -30.35% | -$7.65M | 1.8 | |
| Samsara Biocapital Llc | $17.29M | 4.56 | 2.78M | 0% | +$0 | 2.7 | |
| Point72 Asset Management | $17.06M | 4.5 | 2.74M | -8.59% | -$1.6M | 0.03 | |
| Vr Adviser Llc | $16.02M | 4.23 | 2.58M | +0.02% | +$3,110.00 | 0.78 | |
| The Vanguard Group | $9.21M | 2.43 | 1.48M | +38.27% | +$2.55M | <0.0001 | |
| Pura Vida Investments LLC | $8.79M | 2.32 | 1.41M | 0% | +$0 | 6.26 | |
| Ikarian Capital LLC | $6.57M | 1.73 | 1.06M | -15.75% | -$1.23M | 1.88 | |
| Ally Bridge Group | $6.24M | 1.65 | 1M | New | +$6.24M | 3.51 | |
| Tri Locum Partners Lp | $6.09M | 1.61 | 978,793 | New | +$6.09M | 2.15 | |
| Verition Fund Management Llc | $4.78M | 1.26 | 768,214 | New | +$4.78M | 0.05 | |
| Laurion Capital Management LP | $4.65M | 1.23 | 747,827 | +1,662.74% | +$4.39M | 0.13 | |
| Woodline Partners LP | $4.21M | 1.11 | 676,554 | +12.76% | +$476,321.39 | 0.04 | |
| Parkman Healthcare Partners Llc | $3.99M | 1.05 | 642,245 | -14.92% | -$700,620.82 | 0.49 | |
| Ensign Peak Advisors Inc | $3.68M | 0.97 | 591,311 | +96.1% | +$1.8M | 0.01 | |
| Invesco | $3.45M | 0.91 | 555,233 | New | +$3.45M | <0.01 | |
| Walleye Capital | $3.28M | 0.87 | 528,118 | +3,419.38% | +$3.19M | 0.01 | |
| Millennium Management LLC | $2.53M | 0.67 | 406,121 | +24.58% | +$498,383.79 | <0.01 | |
| Geode Capital Management | $2.24M | 0.59 | 359,431 | +6.83% | +$142,923.20 | <0.0001 | |
| Schonfeld Group | $2.22M | 0.59 | 357,319 | +756.61% | +$1.96M | 0.02 | |
| Susquehanna International Group | $2.14M | 0.56 | 343,322 | +32.34% | +$521,895.36 | <0.01 | |
| Goldman Sachs | $2.08M | 0.55 | 334,665 | +2,461.93% | +$2M | <0.0001 | |
| Hudson Bay Capital Management LP | $1.55M | 0.41 | 250,000 | New | +$1.55M | 0.02 | |
| Boothbay Fund Management LLC | $1.45M | 0.38 | 232,670 | -6.91% | -$107,413.15 | 0.05 | |
| Dimensional Fund Advisors | $1.19M | 0.31 | 190,986 | +69.56% | +$487,349.47 | <0.0001 | |
| Two Sigma | $1.14M | 0.3 | 183,743 | +38.56% | +$318,072.01 | <0.01 | |
| ACUTA CAPITAL PARTNERS LLC | $1.08M | 0.28 | 173,320 | New | +$1.08M | 0.7 | |
| Bank of America | $992,693.00 | 0.26 | 159,597 | +10.31% | +$92,796.15 | <0.0001 | |
| Jane Street Capital | $980,913.00 | 0.26 | 157,703 | +101.53% | +$494,191.61 | <0.01 | |
| BlackRock | $944,936.00 | 0.25 | 151,919 | +37.12% | +$255,778.79 | <0.0001 | |
| Two Sigma Advisers LP | $895,058.00 | 0.24 | 143,900 | +183.83% | +$579,704.00 | <0.01 | |
| Qube Research & Technologies | $820,430.00 | 0.22 | 131,902 | +137.88% | +$475,537.41 | <0.01 | |
| State Street | $784,840.00 | 0.21 | 126,180 | +15.57% | +$105,740.05 | <0.0001 | |
| Citigroup | $739,402.00 | 0.2 | 118,875 | -4.47% | -$34,632.94 | <0.01 | |
| Clearline Capital LP | $740,976.00 | 0.2 | 119,128 | 0% | +$0 | 0.07 | |
| JPMorgan Chase | $680,499.00 | 0.18 | 109,405 | +229.83% | +$474,181.63 | <0.0001 | |
| Hrt Financial Llc | $612,000.00 | 0.16 | 98,525 | New | +$612,000.00 | <0.01 | |
| Man Group Plc | $561,560.00 | 0.15 | 90,283 | +137.57% | +$325,181.45 | <0.01 | |
| Bridgeway Capital Management | $539,896.00 | 0.14 | 86,800 | -38.79% | -$342,100.00 | 0.01 | |
| Marathon Trading Investment Management Llc | $416,802.00 | 0.11 | 67,010 | New | +$416,802.00 | 0.16 | |
| Morgan Stanley | $400,519.00 | 0.11 | 64,392 | New | +$400,519.00 | <0.0001 | |
| Northern Trust | $376,279.00 | 0.1 | 60,495 | -1.71% | -$6,555.88 | <0.0001 | |
| Renaissance Technologies | $317,000.00 | 0.08 | 50,900 | +15.95% | +$43,595.29 | <0.01 | |
| Cambridge Investment Research Advisors Inc | $259,000.00 | 0.07 | 41,563 | New | +$259,000.00 | <0.01 | |
| Barclays | $204,000.00 | 0.05 | 32,817 | 0% | +$0 | <0.0001 | |
| ExodusPoint Capital Management, LP | $200,000.00 | 0.05 | 32,118 | +10.58% | +$19,135.69 | <0.01 | |
| Letko Brosseau | $198,418.00 | 0.05 | 31,900 | 0% | +$0 | <0.01 | |
| Balyasny Asset Management Llc | $195,675.00 | 0.05 | 31,459 | +9.25% | +$16,570.08 | <0.01 | |
| American Century Investments | $160,339.00 | 0.04 | 25,778 | New | +$160,339.00 | <0.0001 |