Lyra Therapeutics, Inc. (LYRA) Insider Trading Activity

NASDAQ$0.495
Market Cap
$878,567.00
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
663 of 881
Rank in Industry
387 of 504

LYRA Insider Trading Activity

LYRA Median Price and Trade Amounts History Chart

Statistics of Insider Transactions

Amount of Insider Buys and Sells

Buys
$0
0
0
Sells
$555,085
10
100

Related Transactions

Cavalier JasonChief Financial Officer
0
$0
2
$8,681
$-8,681
Palasis MariaPresident & CEO
0
$0
2
$19,670
$-19,670
PERCEPTIVE ADVISORS LLC10 percent owner
0
$0
6
$526,734
$-526,734

About Lyra Therapeutics, Inc.

Lyra Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of anti-inflammatory therapies for the treatment of patients with chronic rhinosinusitis. Its technology is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix which is in Phase III clinical trial for the treatment of chronic rhinosinusitis (CRS); and LYR-220 for CRS patients who have failed previous medical management and continue to require treatment to manage CRS symptoms. It has a collaboration agreement with LianBio Inflammatory Limited to develop and commercialize LYR-210 in mainland China, Hong Kong, Taiwan, Macau, South Korea, Singapore, and Thailand. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.

Insider Activity of Lyra Therapeutics, Inc.

Over the last 12 months, insiders at Lyra Therapeutics, Inc. have bought $0 and sold $555,085 worth of Lyra Therapeutics, Inc. stock.

On average, over the past 5 years, insiders at Lyra Therapeutics, Inc. have bought $33.37M and sold $555,085 worth of stock each year.

There was no buying activity among insiders over the last 12 months.

The last purchase of 25,000 shares for transaction amount of $74,095 was made by Waksal Harlan (Executive Chair) on 2023‑11‑10.

List of Insider Buy and Sell Transactions, Lyra Therapeutics, Inc.

2026-01-06SalePalasis MariaPresident & CEO
1,702
0.0777%
$3.36
$5,726
-55.65%
2026-01-06SaleCavalier JasonChief Financial Officer
769
0.0351%
$3.36
$2,587
-55.65%
2025-11-13SalePERCEPTIVE ADVISORS LLC10 percent owner
31,810
1.6829%
$3.90
$124,062
-44.24%
2025-11-12SalePERCEPTIVE ADVISORS LLC10 percent owner
8,745
0.4815%
$4.06
$35,499
-43.30%
2025-11-11SalePERCEPTIVE ADVISORS LLC10 percent owner
5,320
0.3114%
$4.31
$22,954
-47.52%
2025-11-10SalePERCEPTIVE ADVISORS LLC10 percent owner
18,502
1.1394%
$4.54
$83,995
-48.98%
2025-11-07SalePERCEPTIVE ADVISORS LLC10 percent owner
19,739
1.271%
$4.75
$93,695
-50.22%
2025-11-06SalePERCEPTIVE ADVISORS LLC10 percent owner
32,149
2.2589%
$5.18
$166,529
-52.24%
2025-07-10SalePalasis MariaPresident & CEO
1,565
0.1892%
$8.91
$13,944
-50.33%
2025-07-10SaleCavalier JasonChief Financial Officer
684
0.0827%
$8.91
$6,094
-50.33%
2023-11-10PurchaseWaksal HarlanExecutive Chair
25,000
0.0498%
$2.96
$74,095
-87.57%
2023-05-31PurchasePERCEPTIVE ADVISORS LLC
3.61M
9.5077%
$2.49
$9M
+49.42%
2023-05-31PurchaseNBVM GP, LLC10 percent owner
1.81M
4.6346%
$2.43
$4.39M
+49.42%
2023-05-31PurchaseNBVM GP, LLC10 percent owner
1.2M
3.0898%
$2.43
$2.92M
+49.42%
2023-05-31PurchaseANDERSON EDWARD T
1.81M
4.6346%
$2.43
$4.39M
+49.42%
2022-06-10PurchaseMERRIFIELD C ANN
4,000
0.0119%
$5.05
$20,200
-35.30%
2022-05-13PurchaseMERRIFIELD C ANNdirector
3,828
0.0112%
$4.83
$18,486
-19.36%
2022-05-13PurchaseMERRIFIELD C ANN
328
0.001%
$5.00
$1,640
-19.36%
2022-04-12PurchasePERCEPTIVE ADVISORS LLC
5.92M
11.8975%
$4.22
$25M
-21.89%
2022-04-12PurchaseEDELMAN JOSEPH
5.92M
11.8975%
$4.22
$25M
-21.89%
Total: 43
*Gray background shows transactions not older than one year

Insider Historical Profitability

<0.0001%
Palasis MariaPresident & CEO
1096733
61.7919%
$542,882.8402
Cavalier JasonChief Financial Officer
518547
29.2158%
$256,680.7702
PERCEPTIVE ADVISORS LLC10 percent owner
14026
0.7902%
$6,942.8746
EDELMAN JOSEPH
7858285
442.7495%
$3.89M10
ANDERSON EDWARD T
2521745
142.0795%
$1.25M52
NBVM GP, LLC10 percent owner
2521745
142.0795%
$1.25M52
North Bridge Venture Management VI, L.P.
1318133
74.2659%
$652,475.8410
Polaris Venture Management Co. V, L.L.C.10 percent owner
1062259
59.8495%
$525,818.2111
Waksal HarlanExecutive Chair
261966
14.7596%
$129,673.1720
Soleus Private Equity GP I, LLC10 percent owner
155000
8.733%
$76,725.0022
MERRIFIELD C ANN
11328
0.6382%
$5,607.3640
snyderman nancy lynn MDdirector
1025
0.0578%
$507.3810
<0.0001%
*Gray background shows insiders who have made transactions during last year

Historical Insider Profitability vs. Competitors

$1,848,072
66
-14.67%
$2.55M
$53,490,060
55
19.35%
$3.21M
$1,138,733
28
-4.94%
$3.41M
$374,478
22
-36.36%
$2.49M
$8,079,884
14
-43.20%
$2.01M
$82,890
11
-16.71%
$1.73M
$389,864
11
12.52%
$2.48M
$18,269
10
-21.15%
$2.73M
$126,023
10
-66.17%
$1.86M
$90,087
9
20.06%
$4.4M
$7,268,979
7
-48.44%
$2.29M
$70,828
6
-57.96%
$1.56M
$726,438
4
-72.85%
$1.02M
$149,778
4
-45.16%
$3.06M
$23,454
1
-99.16%
$4,356.00
$37,000
1
79.42%
$3.33M
Lyra Therapeutics, Inc.
(LYRA)
$9,963
1
-14.25%
$878,567.00
$19,863
1
144.27%
$849,022.00
$1,049,630
1
-74.91%
$817,868.00

LYRA Institutional Investors: Active Positions

Increased Positions9+28.13%77,552+17.29%
Decreased Positions12-37.5%283,524-63.2%
New Positions3New25,583New
Sold Out Positions6Sold Out278,522Sold Out
Total Postitions29-9.38%242,640-45.91%

LYRA Ownership Change vs Market

Institutional Investor Ownership

Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
Active Shareholders

Financial Ratios

Summary
Comparison with Competitors

Price to Earnings

Price/Earnings to Growth

Price to Sales

Price to Book

Price/Free Cash Flow

Analyst Recommendations

Analyst Price Targets

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Information is provided 'as-is' and solely for informational purposes and is not advice. Prismo does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.