MeiraGTx Holdings plc (MGTX)
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MGTX Stock Price History Chart
MGTX Stock Performance
About MeiraGTx Holdings plc
MeiraGTx Holdings plc, a clinical stage gene therapy company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited blindness, as well as Xerostomia following radiation treatment for head and neck cancers; degenerative diseases; neurodegenerative diseases, such as amyotrophic lateral sclerosis; and Parkinson's diseases. Its programs in clinical development include Phase 1/2 clinical stage programs in Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, and radiation-induced Xerostomia, as well as Parkinson's program. The company also focuses on initiating a clinical program in xerostomia related to Sjogren's syndrome and have preclinical programs in neurodegenerative diseases. It has a research collaboration agreement with Janssen Pharmaceuticals, Inc. to develop regulatable gene therapy treatment using the company's proprietary riboswitch technology. MeiraGTx Holdings plc was incorporated in 2015 and is based in New York, New York.
Insider Activity of MeiraGTx Holdings plc
Over the last 12 months, insiders at MeiraGTx Holdings plc have bought $0 and sold $0 worth of MeiraGTx Holdings plc stock.
On average, over the past 5 years, insiders at MeiraGTx Holdings plc have bought $14.51M and sold $4.69M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 4,347,826 shares for transaction amount of $25M was made by PERCEPTIVE ADVISORS LLC () on 2023‑05‑05.
List of Insider Buy and Sell Transactions, MeiraGTx Holdings plc
| 2023-05-05 | PERCEPTIVE ADVISORS LLC | 4.35M 8.3577% | $5.75 | $25M | -1.95% | |||
| 2022-06-03 | Zeldin Robert K | CHIEF MEDICAL OFFICER | 6 <0.0001% | $7.89 | $47 | -6.73% | ||
| 2022-05-25 | Wollin Robert J | GENERAL COUNSEL AND SECRETARY | 1,000 0.0022% | $7.94 | $7,940 | -5.28% | ||
| 2021-11-17 | Sale | Forbes Alexandria | President and CEO | 30,000 0.0679% | $19.86 | $595,800 | -51.18% | |
| 2021-11-16 | Sale | Forbes Alexandria | President and CEO | 30,000 0.0678% | $19.97 | $599,144 | -51.10% | |
| 2021-10-20 | Sale | Giroux Richard | CFO & COO | 41,400 0.0941% | $21.05 | $871,371 | -40.21% | |
| 2021-10-19 | Sale | Giroux Richard | CFO & COO | 2,600 0.0062% | $20.07 | $52,182 | -33.88% | |
| 2021-10-18 | Sale | Forbes Alexandria | President and CEO | 60,000 0.1271% | $17.36 | $1.04M | -31.36% | |
| 2021-10-18 | Sale | Naylor Stuart | Chief Development Officer | 24,000 0.0526% | $17.95 | $430,800 | -31.36% | |
| 2021-07-20 | Sale | Naylor Stuart | Chief Development Officer | 18,780 0.0419% | $15.06 | $282,827 | -10.03% | |
| 2021-07-13 | Sale | Naylor Stuart | Chief Development Officer | 5,220 0.0119% | $15.04 | $78,509 | -6.75% | |
| 2021-06-09 | Sale | Forbes Alexandria | President and CEO | 8,306 0.0187% | $15.04 | $124,922 | -6.21% | |
| 2021-06-08 | Sale | Forbes Alexandria | President and CEO | 40,360 0.0917% | $15.02 | $606,207 | -5.14% | |
| 2021-06-08 | Sale | Naylor Stuart | Chief Development Officer | 10,080 0.0229% | $15.01 | $151,301 | -5.14% | |
| 2021-06-07 | Sale | Forbes Alexandria | President and CEO | 11,334 0.026% | $15.03 | $170,350 | -4.05% | |
| 2021-06-07 | Sale | Naylor Stuart | Chief Development Officer | 2,084 0.0048% | $15.02 | $31,302 | -4.05% | |
| 2021-04-30 | Sale | Naylor Stuart | Chief Development Officer | 741 0.0017% | $15.01 | $11,122 | -4.34% | |
| 2021-04-29 | Sale | Naylor Stuart | Chief Development Officer | 1,405 0.0032% | $15.02 | $21,103 | -4.47% | |
| 2021-04-28 | Sale | Naylor Stuart | Chief Development Officer | 3,772 0.0087% | $15.14 | $57,108 | -3.43% | |
| 2021-02-17 | Sale | Forbes Alexandria | President and CEO | 30,000 0.0669% | $15.57 | $467,100 | -6.58% |
Insider Historical Profitability
| PERCEPTIVE ADVISORS LLC | 11281103 17.7384% | $4.21 | 5 | 0 | <0.0001% | |
| PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | 10 percent owner | 6007746 9.4466% | $4.21 | 1 | 0 | +18.44% |
| Forbes Alexandria | President and CEO | 1080781 1.6994% | $4.21 | 0 | 20 | |
| Giroux Richard | CFO & COO | 819218 1.2881% | $4.21 | 0 | 8 | |
| Naylor Stuart | Chief Development Officer | 402017 0.6321% | $4.21 | 0 | 20 | |
| SHENK THOMAS E | director | 157476 0.2476% | $4.21 | 0 | 3 | |
| Seligman Nicole | director | 5000 0.0079% | $4.21 | 1 | 0 | <0.0001% |
| Zeldin Robert K | CHIEF MEDICAL OFFICER | 5000 0.0079% | $4.21 | 1 | 0 | <0.0001% |
| Wollin Robert J | GENERAL COUNSEL AND SECRETARY | 1000 0.0016% | $4.21 | 1 | 0 | <0.0001% |
| MARCUS JOEL S | director | 0 0% | $4.21 | 0 | 3 |
Institutional Investor Ownership
| Perceptive Advisors | $68.72M | 17.62 | 11.33M | 0% | +$0 | 0.05 | |
| Johnson & Johnson | $40.31M | 10.33 | 6.64M | 0% | +$0 | 0.91 | |
| Adage Capital Partners Gp L L C | $32.12M | 8.23 | 5.29M | 0% | +$0 | 0.06 | |
| Prosight Management Lp | $24.39M | 6.25 | 4.02M | -0.82% | -$202,816.91 | 6.78 | |
| 683 Capital Management Llc | $15.18M | 3.89 | 2.5M | 0% | +$0 | 1.7 | |
| BlackRock | $13.28M | 3.4 | 2.19M | -1.41% | -$189,863.51 | <0.0001 | |
| ROYCE & ASSOCIATES INC | $4.2M | 1.08 | 692,115 | +2.98% | +$121,400.00 | 0.04 | |
| State Street | $3.46M | 0.89 | 569,816 | +1.46% | +$49,761.86 | <0.0001 | |
| Dimensional Fund Advisors | $2.45M | 0.63 | 404,096 | -6.73% | -$176,958.66 | <0.01 | |
| Geode Capital Management | $2.42M | 0.62 | 398,094 | +2.72% | +$64,014.21 | <0.0001 | |
| Laurion Capital Management LP | $2.23M | 0.57 | 367,937 | 0% | +$0 | 0.06 | |
| JPMorgan Chase | $2.18M | 0.56 | 358,449 | -6.76% | -$157,789.62 | <0.0001 | |
| Alyeska Investment Group L P | $2M | 0.51 | 330,182 | 0% | +$0 | 0.01 | |
| The Vanguard Group | $1.97M | 0.5 | 323,891 | +3.67% | +$69,622.92 | <0.0001 | |
| Millennium Management LLC | $1.76M | 0.45 | 290,770 | +115.42% | +$945,675.70 | <0.01 | |
| Northern Trust | $1.47M | 0.38 | 242,747 | -0.74% | -$10,938.14 | <0.0001 | |
| Russell Investments Group Ltd | $959,052.00 | 0.25 | 157,999 | +1.93% | +$18,173.54 | <0.01 | |
| Wellington Management Company | $910,264.00 | 0.23 | 149,961 | +2.39% | +$21,275.37 | <0.0001 | |
| J. Goldman & Company | $819,450.00 | 0.21 | 135,000 | New | +$819,450.00 | 0.04 | |
| Nuveen | $810,794.00 | 0.21 | 133,574 | 0% | +$0 | <0.0001 | |
| Blair William Co Il | $802,047.00 | 0.21 | 132,133 | 0% | +$0 | <0.01 | |
| BNY Mellon | $795,528.00 | 0.2 | 131,059 | -12.08% | -$109,320.68 | <0.0001 | |
| Privium Fund Management | $728,309.00 | 0.19 | 119,985 | New | +$728,309.00 | 0.21 | |
| Los Angeles Capital Management LLC | $705,959.00 | 0.18 | 116,303 | New | +$705,959.00 | <0.01 | |
| Renaissance Technologies | $662,000.00 | 0.17 | 109,100 | +35.7% | +$174,146.65 | <0.01 | |
| Morgan Stanley | $576,590.00 | 0.15 | 94,990 | -22.46% | -$166,985.90 | <0.0001 | |
| Davenport & Company | $518,257.00 | 0.13 | 85,380 | +41.46% | +$151,901.87 | <0.01 | |
| Bank of America | $477,357.00 | 0.12 | 78,642 | +59.85% | +$178,737.24 | <0.0001 | |
| Barclays | $465,000.00 | 0.12 | 76,759 | -22.19% | -$132,626.08 | <0.0001 | |
| Charles Schwab | $452,482.00 | 0.12 | 74,544 | 0% | +$0 | <0.0001 | |
| Change Path Llc | $436,000.00 | 0.11 | 71,823 | -6.65% | -$31,074.78 | 0.02 | |
| Fort Sheridan Advisors Llc | $432,921.00 | 0.11 | 71,321 | -2.82% | -$12,546.76 | 0.08 | |
| D. E. Shaw & Co. | $417,555.00 | 0.11 | 68,790 | +88.03% | +$195,490.28 | <0.01 | |
| Citadel Advisors LLC | $415,364.00 | 0.11 | 68,429 | -71.04% | -$1.02M | <0.0001 | |
| State of Wisconsin Investment Board | $389,694.00 | 0.1 | 64,200 | +52.13% | +$133,540.00 | <0.01 | |
| Goldman Sachs | $330,184.00 | 0.09 | 54,396 | -46.84% | -$290,868.58 | <0.0001 | |
| RhumbLine Advisers | $290,245.00 | 0.07 | 47,818 | +2.91% | +$8,206.35 | <0.0001 | |
| AllianceBernstein | $257,611.00 | 0.07 | 42,440 | 0% | +$0 | <0.0001 | |
| Tocqueville Asset Management | $239,765.00 | 0.06 | 39,500 | +16.35% | +$33,688.50 | <0.01 | |
| Cubist Systematic Strategies | $229,263.00 | 0.06 | 37,770 | +166.16% | +$143,123.97 | <0.01 | |
| UBS | $229,713.00 | 0.06 | 37,844 | +3.75% | +$8,297.69 | <0.0001 | |
| Letko Brosseau | $198,489.00 | 0.05 | 32,700 | 0% | +$0 | <0.01 | |
| Cornercap Investment Counsel Inc | $194,009.00 | 0.05 | 31,962 | -0.38% | -$734.47 | 0.03 | |
| Deutsche Bank | $188,990.00 | 0.05 | 31,135 | -3.08% | -$5,997.18 | <0.0001 | |
| American Century Investments | $170,573.00 | 0.04 | 28,101 | New | +$170,573.00 | <0.0001 | |
| Jane Street Capital | $160,205.00 | 0.04 | 26,393 | -66.05% | -$311,681.37 | <0.0001 | |
| Xtx Topco Ltd | $134,086.00 | 0.03 | 22,090 | +6.35% | +$8,006.31 | 0.01 | |
| Invesco | $114,073.00 | 0.03 | 18,793 | +6.1% | +$6,555.57 | <0.0001 | |
| Jump Financial Llc | $109,903.00 | 0.03 | 18,106 | -65.8% | -$211,429.43 | <0.01 | |
| Kennedy Capital Management Inc | $99,894.00 | 0.03 | 16,457 | New | +$99,894.00 | <0.01 |