Regulus Therapeutics Inc. (RGLS)
NASDAQ
Market Cap
$133.55M
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
730 of 809
Rank in Industry
399 of 445
Largest Insider Buys in Sector
RGLS Stock Price History Chart
RGLS Stock Performance
About Regulus Therapeutics Inc.
Regulus Therapeutics Inc., a clinical stage biopharmaceutical company, engages in the discovery and development of drugs that targets microRNAs to treat a range of diseases in the United States. Its product candidates include RG-012, an anti-miR targeting miR-21 that is in Phase II clinical trial for the treatment of Alport syndrome, a life-threatening kidney disease; and RGLS8429, an anti-miR targeting miR-17, which is in Phase 1b clinical study for the treatment of autosomal dominant polycystic kidney disease. The company is also developing a pipeline of preclinical drug products for target organ-selective delivery strategies. Regulus Therapeutics Inc. was incorporated in 2007 and is headquartered in San Diego, California.
Insider Activity of Regulus Therapeutics Inc.
Over the last 12 months, insiders at Regulus Therapeutics Inc. have bought $0 and sold $30,379 worth of Regulus Therapeutics Inc. stock.
On average, over the past 5 years, insiders at Regulus Therapeutics Inc. have bought $13.7M and sold $32,266 worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 76,686 shares for transaction amount of $17,638 was made by Drygin Denis (Chief Scientific Officer) on 2022‑03‑01.
List of Insider Buy and Sell Transactions, Regulus Therapeutics Inc.
| 2024-01-18 | Sale | Hagan Joseph P | Chief Executive Officer | 14,580 0.0687% | $1.19 | $17,359 | +76.80% | |
| 2024-01-18 | Sale | Aker Christopher Ray | Sr. VP & General Counsel | 5,468 0.0258% | $1.19 | $6,510 | +76.80% | |
| 2024-01-18 | Sale | CALSADA CRISPINA | Chief Financial Officer | 5,468 0.0258% | $1.19 | $6,510 | +76.80% | |
| 2022-03-01 | Drygin Denis | Chief Scientific Officer | 76,686 0.0537% | $0.23 | $17,638 | -25.22% | ||
| 2022-02-04 | Drygin Denis | Chief Scientific Officer | 23,314 0.0156% | $0.23 | $5,362 | -25.63% | ||
| 2022-01-26 | Hagan Joseph P | President and CEO | 100,000 0.0685% | $0.22 | $21,520 | -15.91% | ||
| 2021-05-17 | Sale | Hagan Joseph P | President and CEO | 4,186 0.0053% | $0.89 | $3,726 | -53.85% | |
| 2021-05-17 | Sale | Aker Christopher Ray | Sr. VP & General Counsel | 860 0.0011% | $0.89 | $765 | -53.85% | |
| 2021-02-16 | Sale | Hagan Joseph P | President and CEO | 4,144 0.0052% | $1.72 | $7,128 | -62.37% | |
| 2021-02-16 | Sale | Aker Christopher Ray | Sr. VP & General Counsel | 828 0.001% | $1.72 | $1,424 | -62.37% | |
| 2020-12-04 | Walker Paul Edward | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% | ||
| 2020-12-04 | Sonsini Peter W. | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% | ||
| 2020-12-04 | SANDELL SCOTT D | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% | ||
| 2020-12-04 | MAKOWER JOSHUA | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% | ||
| 2020-12-04 | Makhzoumi Mohamad | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% | ||
| 2020-12-04 | Growth Equity Opportunities V, LLC | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% | ||
| 2020-12-04 | Florence Anthony A. Jr. | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% | ||
| 2020-12-04 | Chang Carmen | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% | ||
| 2020-12-04 | Behbahani Ali | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% | ||
| 2020-12-04 | BASKETT FOREST | 10 percent owner | 4.4M 7.578% | $0.62 | $2.74M | +22.37% |
Insider Historical Profitability
<0.0001%
| Hagan Joseph P | Chief Executive Officer | 57112 0.2824% | $2.04 | 4 | 14 | <0.0001% |
| Aker Christopher Ray | Sr. VP & General Counsel | 10056 0.0497% | $2.04 | 0 | 14 | |
| CALSADA CRISPINA | Chief Financial Officer | 5782 0.0286% | $2.04 | 0 | 1 | |
| CROOKE STANLEY T | 7049500 34.8593% | $2.04 | 1 | 0 | ||
| PARSHALL B LYNNE | 7049500 34.8593% | $2.04 | 1 | 0 | ||
| Chang Carmen | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| Behbahani Ali | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| BASKETT FOREST | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| MAKOWER JOSHUA | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| SANDELL SCOTT D | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| Sonsini Peter W. | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| Makhzoumi Mohamad | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| Walker Paul Edward | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| Florence Anthony A. Jr. | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| Growth Equity Opportunities V, LLC | 10 percent owner | 6451056 31.9001% | $2.04 | 2 | 0 | <0.0001% |
| ISIS PHARMACEUTICALS INC | 10 percent owner | 5173172 25.581% | $2.04 | 1 | 58 | |
| Sanofi | 10 percent owner | 5053779 24.9906% | $2.04 | 1 | 0 | |
| ALNYLAM PHARMACEUTICALS, INC. | 10 percent owner | 4896716 24.214% | $2.04 | 0 | 54 | |
| ASTRAZENECA PLC | 10 percent owner | 4250000 21.016% | $2.04 | 0 | 1 | |
| MOTT DAVID M | 10 percent owner | 2052454 10.1493% | $2.04 | 1 | 0 | <0.0001% |
| BARRIS PETER J | 10 percent owner | 2052454 10.1493% | $2.04 | 1 | 0 | <0.0001% |
| PAPADOPOULOS STELIOS | director | 1189872 5.8838% | $2.04 | 9 | 0 | <0.0001% |
| WRIGHT TIMOTHY MICHAEL | Chief R & D Officer | 274725 1.3585% | $2.04 | 1 | 0 | <0.0001% |
| RASTETTER WILLIAM H | director | 154223 0.7626% | $2.04 | 5 | 0 | <0.0001% |
| Drygin Denis | Chief Scientific Officer | 100000 0.4945% | $2.04 | 2 | 0 | <0.0001% |
| Chevallard Daniel R. | Chief Financial Officer | 77870 0.3851% | $2.04 | 1 | 3 | <0.0001% |
| Witz Pascale | director | 37849 0.1872% | $2.04 | 1 | 0 | <0.0001% |
| Collier Kathryn J | director | 27596 0.1365% | $2.04 | 1 | 0 | <0.0001% |
| FOLETTA MARK G | director | 10000 0.0494% | $2.04 | 1 | 0 | <0.0001% |
| XANTHOPOULOS KLEANTHIS G | President and CEO | 3705 0.0183% | $2.04 | 0 | 23 | |
| Gibson Neil W | Chief Scientific Officer | 0 0% | $2.04 | 0 | 14 | |
| CARTER BRUCE L A | director | 0 0% | $2.04 | 0 | 1 |
Institutional Investor Ownership
Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
| Federated Hermes | $34.43M | 19.63 | 12.85M | +231.63% | +$24.05M | 0.08 | |
| Nea Management Company Llc | $18.63M | 9.88 | 6.47M | +232.44% | +$13.02M | 0.21 | |
| RA Capital Management, L.P. | $18M | 9.55 | 6.25M | New | +$18M | 0.02 | |
| Vivo Capital | $14.4M | 7.64 | 5M | New | +$14.4M | 1.27 | |
| Adage Capital Partners Gp L L C | $10.6M | 5.62 | 3.68M | New | +$10.6M | 0.02 | |
| Deep Track Capital Lp | $9.41M | 4.99 | 3.27M | New | +$9.41M | 0.04 | |
| Fidelity Investments | $8.42M | 4.46 | 2.92M | 0% | +$0 | <0.01 | |
| Millennium Management LLC | $5.4M | 2.86 | 1.88M | New | +$5.4M | <0.01 | |
| Soleus Capital Management, L.P. | $4.5M | 2.39 | 1.56M | New | +$4.5M | 0.04 | |
| Cvi Holdings Llc | $4.05M | 2.15 | 1.41M | New | +$4.05M | 4.18 | |
| DAFNA Capital Management, LLC | $3.08M | 1.64 | 1.07M | -3.65% | -$116,642.87 | 0.72 | |
| Alyeska Investment Group L P | $2.68M | 1.43 | 937,500 | New | +$2.68M | 0.02 | |
| The Vanguard Group | $2.13M | 1.13 | 740,215 | +158.43% | +$1.31M | <0.0001 | |
| Monashee Investment Management LLC | $1.8M | 0.96 | 625,000 | New | +$1.8M | 0.16 | |
| Hudson Bay Capital Management LP | $1.68M | 0.96 | 625,000 | New | +$1.68M | 0.02 | |
| Polar Asset Management Partners Inc | $1.54M | 0.82 | 536,400 | New | +$1.54M | 0.03 | |
| Victory Capital Management Inc | $1.06M | 0.56 | 368,146 | +35.48% | +$277,660.67 | <0.01 | |
| Goldman Sachs | $654,967.00 | 0.35 | 227,419 | New | +$654,967.00 | <0.0001 | |
| Sarissa Capital Management LP | $533,327.00 | 0.28 | 185,183 | 0% | +$0 | 0.09 | |
| Opaleye Management Inc | $490,487.00 | 0.26 | 170,308 | New | +$490,487.00 | 0.08 | |
| Geode Capital Management | $462,629.00 | 0.25 | 160,590 | +31.07% | +$109,669.49 | <0.0001 | |
| Prelude Capital | $381,514.00 | 0.2 | 132,470 | +229.04% | +$265,565.08 | 0.03 | |
| LINSCO PRIVATE LEDGER CORP | $326,822.00 | 0.17 | 113,480 | New | +$326,822.00 | <0.0001 | |
| Renaissance Technologies | $217,000.00 | 0.12 | 75,500 | +38.28% | +$60,070.20 | <0.0001 | |
| Simplex Trading Llc | $217,000.00 | 0.12 | 75,450 | New | +$217,000.00 | 0.01 | |
| BlackRock | $195,929.00 | 0.1 | 68,031 | +11,772.77% | +$194,278.76 | <0.0001 | |
| Hrt Financial Llc | $180,000.00 | 0.1 | 62,797 | New | +$180,000.00 | <0.01 | |
| State Street | $120,151.00 | 0.06 | 41,719 | 0% | +$0 | <0.0001 | |
| Morgan Stanley | $80,119.00 | 0.04 | 27,819 | New | +$80,119.00 | <0.0001 | |
| Balyasny Asset Management Llc | $69,849.00 | 0.04 | 24,253 | New | +$69,849.00 | <0.0001 | |
| Susquehanna International Group | $64,881.00 | 0.03 | 22,528 | New | +$64,881.00 | <0.0001 | |
| JPMorgan Chase | $56,857.00 | 0.03 | 19,742 | +67,975.86% | +$56,773.48 | <0.0001 | |
| Northern Trust | $51,777.00 | 0.03 | 17,978 | 0% | +$0 | <0.0001 | |
| Citigroup | $40,801.00 | 0.02 | 14,167 | +567.31% | +$34,686.75 | <0.0001 | |
| Grimes & Company | $29,560.00 | 0.02 | 10,264 | -1.5% | -$449.27 | <0.01 | |
| Group One Trading | $24,788.00 | 0.01 | 8,607 | New | +$24,788.00 | <0.01 | |
| Tower Research Capital | $9,250.00 | 0.01 | 3,212 | +18,794.12% | +$9,201.04 | <0.0001 | |
| Macquarie Group | $2,000.00 | <0.01 | 865 | New | +$2,000.00 | <0.0001 | |
| Community Bank, N.A. | $1,980.00 | <0.01 | 690 | 0% | +$0 | <0.0001 | |
| UBS | $870.00 | <0.01 | 302 | -12.21% | -$120.99 | <0.0001 | |
| Royal Bank of Canada | $0 | <0.01 | 51 | -36.25% | -$0 | <0.0001 | |
| Wells Fargo | $409.00 | <0.01 | 142 | +1.43% | +$5.76 | <0.0001 |