Repare Therapeutics Inc., a clinical-stage precision oncology company, discovers and develops therapeutics by using its synthetic lethality approach in Canada and the United States. The company uses its SNIPRx, a proprietary, genome-wide, and CRISPR-enabled platform to systematically discover and develop highly targeted cancer therapies that focuses on genomic instability, including DNA damage repair. Its lead product candidate is RP-3500, an oral small molecule inhibitor for the treatment of solid tumors with specific DNA damage repair-related genomic alterations. It is also developing RP-6306, which is under Phase I clinical trial for tumors with genetic alterations characterized by CCNE1 amplification; and Polymerase Theta program, a SL target associated with BRCA mutations and other genomic alterations. The company was incorporated in 2016 and is headquartered in Montreal, Canada.
Over the last 12 months, insiders at Repare Therapeutics Inc. have bought $9.07M and sold $101,063 worth of Repare Therapeutics Inc. stock.
On average, over the past 5 years, insiders at Repare Therapeutics Inc. have bought $53.51M and sold $31.61M worth of stock each year.
Highest buying activity among insiders over the last 12 months: BVF PARTNERS L P/IL (10 percent owner) — $172.35M.
The last purchase of 295,745 shares for transaction amount of $1.59M was made by BVF PARTNERS L P/IL (10 percent owner) on 2023‑11‑16.
2024-04-01 | Sale | Koehler Maria | EVP, CHIEF MEDICAL OFFICER | 300 0.0007% | $4.66 | $1,398 | -25.11% | |
2024-04-01 | Sale | Segal Lloyd Mitchell | PRESIDENT AND CEO | 2,491 0.0058% | $4.63 | $11,533 | -25.11% | |
2024-04-01 | Sale | Zinda Michael | EVP, CHIEF SCIENTIFIC OFFICER | 410 0.001% | $4.66 | $1,911 | -25.11% | |
2024-04-01 | Sale | Forte Steve | EVP, CHIEF FINANCIAL OFFICER | 789 0.0018% | $4.61 | $3,637 | -25.11% | |
2024-03-28 | Sale | Koehler Maria | EVP, CHIEF MEDICAL OFFICER | 500 0.0012% | $4.64 | $2,320 | -25.16% | |
2024-03-28 | Sale | Segal Lloyd Mitchell | PRESIDENT AND CEO | 2,650 0.0062% | $4.62 | $12,243 | -25.16% | |
2024-03-28 | Sale | Zinda Michael | EVP, CHIEF SCIENTIFIC OFFICER | 450 0.0011% | $4.64 | $2,088 | -25.16% | |
2024-03-28 | Sale | Forte Steve | EVP, CHIEF FINANCIAL OFFICER | 825 0.0019% | $4.62 | $3,812 | -25.16% | |
2024-03-27 | Sale | Koehler Maria | EVP, CHIEF MEDICAL OFFICER | 500 0.0012% | $4.62 | $2,310 | -24.41% | |
2024-03-27 | Sale | Segal Lloyd Mitchell | PRESIDENT AND CEO | 2,650 0.0062% | $4.63 | $12,270 | -24.41% | |
2024-03-27 | Sale | Zinda Michael | EVP, CHIEF SCIENTIFIC OFFICER | 450 0.0011% | $4.62 | $2,079 | -24.41% | |
2024-03-27 | Sale | Forte Steve | EVP, CHIEF FINANCIAL OFFICER | 825 0.0019% | $4.62 | $3,812 | -24.41% | |
2024-03-26 | Sale | Koehler Maria | EVP, CHIEF MEDICAL OFFICER | 500 0.0012% | $4.60 | $2,300 | -22.08% | |
2024-03-26 | Sale | Segal Lloyd Mitchell | PRESIDENT AND CEO | 2,650 0.0064% | $4.64 | $12,296 | -22.08% | |
2024-03-26 | Sale | Zinda Michael | EVP, CHIEF SCIENTIFIC OFFICER | 450 0.0011% | $4.61 | $2,075 | -22.08% | |
2024-03-26 | Sale | Forte Steve | EVP, CHIEF FINANCIAL OFFICER | 825 0.002% | $4.60 | $3,795 | -22.08% | |
2024-03-25 | Sale | Koehler Maria | EVP, CHIEF MEDICAL OFFICER | 500 0.0012% | $4.78 | $2,390 | -25.84% | |
2024-03-25 | Sale | Segal Lloyd Mitchell | PRESIDENT AND CEO | 2,650 0.0063% | $4.79 | $12,694 | -25.84% | |
2024-03-25 | Sale | Zinda Michael | EVP, CHIEF SCIENTIFIC OFFICER | 450 0.0011% | $4.78 | $2,151 | -25.84% | |
2024-03-25 | Sale | Forte Steve | EVP, CHIEF FINANCIAL OFFICER | 825 0.002% | $4.79 | $3,952 | -25.84% |
BVF PARTNERS L P/IL | 10 percent owner | 5309432 12.6026% | $3.37 | 4 | 0 | <0.0001% |
Koehler Maria | EVP, CHIEF MEDICAL OFFICER | 231409 0.5486% | $3.37 | 0 | 5 | |
Segal Lloyd Mitchell | President and CEO | 107558 0.2242% | $3.37 | 1 | 13 | <0.0001% |
Zinda Michael | EVP, Chief Scientific Officer | 71908 0.1427% | $3.37 | 0 | 20 | |
Forte Steve | EVP, Chief Financial Officer | 44775 0.0119% | $3.37 | 1 | 5 | <0.0001% |
LAMPERT MARK N | 4443423 10.547% | $3.37 | 3 | 0 | +11.32% | |
GADICKE ANSBERT | 10 percent owner | 3882485 9.2156% | $3.37 | 1 | 30 | <0.0001% |
Versant Vantage I, L.P. | 10 percent owner | 3419451 8.1165% | $3.37 | 1 | 0 | <0.0001% |
Versant Ventures V, LLC | 10 percent owner | 3419451 8.1165% | $3.37 | 1 | 0 | <0.0001% |
MPM BioVentures 2014, L.P. | 10 percent owner | 3003772 7.1298% | $3.37 | 1 | 0 | <0.0001% |
Foley Todd | director | 2242636 5.3232% | $3.37 | 1 | 30 | <0.0001% |
Jerel Davis | director | 2094451 4.9714% | $3.37 | 1 | 2 | <0.0001% |
Versant Ventures V (Canada), L.P. | 111484 0.2646% | $3.37 | 0 | 1 | ||
Bonita David P | director | 96190 0.2283% | $3.37 | 1 | 13 | <0.0001% |
ORBIMED ADVISORS LLC | director | 96190 0.2283% | $3.37 | 1 | 13 | <0.0001% |
Versant Vantage I GP-GP, LLC | 48776 0.1158% | $3.37 | 0 | 1 | ||
SCHAFER CAROL | director | 8000 0.019% | $3.37 | 1 | 0 | <0.0001% |
Civik Thomas | director | 7500 0.0178% | $3.37 | 1 | 0 | <0.0001% |
Morrison Briggs | director | 4800 0.0114% | $3.37 | 1 | 0 | <0.0001% |
RHOADS ANN D | director | 4000 0.0095% | $3.37 | 1 | 0 | <0.0001% |
Bvf Inc Il | $48.67M | 24.35 | 10.33M | 0% | +$0 | 0.36 | |
OrbiMed | $15.65M | 7.83 | 3.32M | 0% | +$0 | 0.32 | |
Blue Owl Capital Holdings Lp | $14.71M | 7.36 | 3.12M | 0% | +$0 | 2.77 | |
ARK Investment Management LLC | $12.73M | 6.37 | 2.7M | -4.17% | -$554,729.76 | 0.09 | |
Deep Track Capital Lp | $12.64M | 6.32 | 2.68M | -10.3% | -$1.45M | 0.06 | |
Versant Ventures | $12.47M | 6.24 | 2.65M | 0% | +$0 | 17.38 | |
MPM Asset Management LLC | $10.56M | 5.28 | 2.24M | 0% | +$0 | 4.31 | |
Redmile Group | $9.5M | 4.75 | 2.02M | -6.16% | -$623,820.63 | 0.35 | |
Bioimpact Capital Llc | $7.72M | 3.86 | 1.64M | 0% | +$0 | 1.25 | |
Artal Group S A | $3.3M | 1.65 | 700,000 | 0% | +$0 | 0.02 | |
Spyglass Capital Management LLC | $2.98M | 1.49 | 633,271 | 0% | +$0 | 2.24 | |
Renaissance Technologies | $1.65M | 0.83 | 351,000 | -1.36% | -$22,727.57 | <0.01 | |
Ensign Peak Advisors Inc | $1.62M | 0.81 | 344,328 | 0% | +$0 | <0.01 | |
Nikko Asset Management Americas Inc | $1.43M | 0.73 | 308,449 | -5.39% | -$81,663.31 | 0.01 | |
Sumitomo Mitsui Trust Holdings | $1.45M | 0.73 | 308,449 | -5.39% | -$82,717.03 | <0.01 | |
Morgan Stanley | $1.35M | 0.68 | 287,529 | -13.72% | -$215,388.36 | <0.0001 | |
Millennium Management LLC | $795,354.00 | 0.4 | 168,865 | -7.27% | -$62,322.71 | <0.01 | |
HighVista Strategies | $777,965.00 | 0.39 | 165,173 | 0% | +$0 | 0.29 | |
Acadian Asset Management | $625,000.00 | 0.32 | 133,893 | +53.47% | +$217,748.50 | <0.01 | |
Gsa Capital Partners Llp | $594,000.00 | 0.3 | 126,208 | -12.63% | -$85,856.27 | 0.05 | |
D. E. Shaw & Co. | $565,826.00 | 0.28 | 120,133 | +55.66% | +$202,313.19 | <0.01 | |
Bank of Montreal | $509,468.00 | 0.25 | 105,262 | +0.29% | +$1,452.00 | <0.0001 | |
Opaleye Management Inc | $318,212.00 | 0.16 | 67,561 | New | +$318,212.00 | 0.05 | |
Citadel Advisors LLC | $313,549.00 | 0.16 | 66,571 | +42.78% | +$93,940.83 | <0.0001 | |
Two Sigma | $314,407.00 | 0.16 | 66,753 | +162.02% | +$194,414.90 | <0.01 | |
BlackRock | $288,559.00 | 0.14 | 61,265 | -2.29% | -$6,763.58 | <0.0001 | |
Harbor Capital Advisors Inc | $286,000.00 | 0.14 | 60,659 | +26.23% | +$59,426.37 | 0.04 | |
The Vanguard Group | $263,011.00 | 0.13 | 55,841 | -10.88% | -$32,112.77 | <0.0001 | |
Exchange Traded Concepts, LLC | $257,095.00 | 0.13 | 54,585 | +301.8% | +$193,109.74 | 0.01 | |
Corton Capital Inc | $217,710.00 | 0.11 | 46,223 | +66.03% | +$86,583.80 | 0.08 | |
Dimensional Fund Advisors | $192,022.00 | 0.1 | 40,769 | -7.48% | -$15,533.58 | <0.0001 | |
Goldman Sachs | $170,912.00 | 0.09 | 36,287 | +25.4% | +$34,613.84 | <0.0001 | |
Cubist Systematic Strategies | $166,819.00 | 0.08 | 35,418 | +32.86% | +$41,254.94 | <0.01 | |
American Century Investments | $152,783.00 | 0.08 | 32,438 | +23.19% | +$28,763.97 | <0.0001 | |
Stifel | $143,184.00 | 0.07 | 30,400 | New | +$143,184.00 | <0.0001 | |
PDT Partners | $141,677.00 | 0.07 | 30,080 | New | +$141,677.00 | 0.01 | |
Squarepoint Ops LLC | $127,443.00 | 0.06 | 27,058 | -50.34% | -$129,190.41 | <0.0001 | |
Geode Capital Management | $125,022.00 | 0.06 | 26,544 | 0% | +$0 | <0.0001 | |
Connor Clark & Lunn Investment Management Ltd | $121,640.00 | 0.06 | 25,826 | +54.38% | +$42,846.71 | <0.0001 | |
Blackstone | $122,257.00 | 0.06 | 25,957 | 0% | +$0 | <0.01 | |
Bank of America | $107,478.00 | 0.05 | 22,819 | +5.52% | +$5,623.77 | <0.0001 | |
ExodusPoint Capital Management, LP | $99,000.00 | 0.05 | 21,076 | New | +$99,000.00 | <0.01 | |
State Street | $93,282.00 | 0.05 | 19,805 | -12.49% | -$13,319.94 | <0.0001 | |
Jane Street Capital | $79,759.00 | 0.04 | 16,934 | -40.45% | -$54,169.61 | <0.0001 | |
Occudo Quantitative Strategies Lp | $72,737.00 | 0.04 | 15,443 | -49.91% | -$72,468.53 | 0.01 | |
Vontobel Holding Ltd | $70,650.00 | 0.04 | 15,000 | 0% | +$0 | <0.01 | |
Susquehanna International Group | $69,176.00 | 0.04 | 14,687 | -45.69% | -$58,187.53 | <0.0001 | |
Compagnie Lombard Odier Scma | $65,940.00 | 0.03 | 14,000 | 0% | +$0 | <0.01 | |
HarbourVest Partners | $57,820.00 | 0.03 | 12,276 | 0% | +$0 | 0.03 | |
Jump Financial Llc | $58,875.00 | 0.03 | 12,500 | -68.44% | -$127,655.13 | <0.0001 |