Spruce Biosciences, Inc. (SPRB)
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SPRB Stock Price History Chart
SPRB Stock Performance
About Spruce Biosciences, Inc.
Spruce Biosciences, Inc., a biopharmaceutical company, focuses on developing and commercializing novel therapies for rare endocrine disorders. The company engages in developing tildacerfont, a non-steroidal therapy to enhance disease control and reduce steroid burden for adult patients suffering from congenital adrenal hyperplasia (CAH), which is in Phase 2b clinical trial; and to evaluate glucocorticoid reduction and clinical consequences in adult patients with classic CAH that is Phase 2b clinical trial. It is also developing tildacerfont for the treatment of pediatric classic congenital adrenal hyperplasia in children that is in Phase 2 clinical trial; and for females with polycystic ovary syndrome, which is in Phase 2 clinical trial. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize compounds for various pharmaceutical uses. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in Daly City, California.
Insider Activity of Spruce Biosciences, Inc.
Over the last 12 months, insiders at Spruce Biosciences, Inc. have bought $0 and sold $3.41M worth of Spruce Biosciences, Inc. stock.
On average, over the past 5 years, insiders at Spruce Biosciences, Inc. have bought $19.12M and sold $5.12M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 2,208,000 shares for transaction amount of $7M was made by Novo Holdings A/S (10 percent owner) on 2023‑02‑16.
List of Insider Buy and Sell Transactions, Spruce Biosciences, Inc.
| 2024-03-21 | Sale | Novo Holdings A/S | 10 percent owner | 465,021 1.1289% | $0.75 | $350,951 | -4.38% | |
| 2024-03-20 | Sale | Novo Holdings A/S | 10 percent owner | 359,979 0.8709% | $0.73 | $264,081 | -3.14% | |
| 2024-03-19 | Sale | Novo Holdings A/S | 10 percent owner | 593,000 1.4693% | $0.76 | $447,715 | -3.45% | |
| 2024-03-18 | Sale | Novo Holdings A/S | 10 percent owner | 842,020 2.0939% | $0.77 | $647,008 | -4.72% | |
| 2024-03-14 | Sale | Novo Holdings A/S | 10 percent owner | 1.91M 0.8272% | $0.89 | $1.7M | -13.53% | |
| 2023-02-16 | Novo Holdings A/S | 10 percent owner | 2.21M 0.0087% | $3.17 | $7M | -11.16% | ||
| 2023-02-16 | O'Donnell Niall | director | 630,400 0.0025% | $3.17 | $2M | -11.16% | ||
| 2021-05-20 | Sale | SIMPSON CAMILLA V | director | 334 0.0014% | $15.29 | $5,107 | -71.33% | |
| 2021-05-19 | Sale | Novo Holdings A/S | 10 percent owner | 475,000 1.8365% | $13.90 | $6.6M | -71.54% | |
| 2021-04-30 | Sale | SIMPSON CAMILLA V | director | 14,045 0.06% | $16.14 | $226,664 | -71.70% | |
| 2020-10-14 | Novo Holdings A/S | 10 percent owner | 250,000 0.9752% | $15.00 | $3.75M | -10.92% | ||
| 2020-10-14 | Omega Fund VI, L.P. | 250,000 0.9752% | $15.00 | $3.75M | -10.92% | |||
| 2020-10-14 | Chaya Moghrabi Dina | director | 250,000 0.9752% | $15.00 | $3.75M | -10.92% | ||
| 2020-10-14 | RiverVest Venture Fund III, L.P. | 10 percent owner | 250,000 0.9752% | $15.00 | $3.75M | -10.92% | ||
| 2020-10-14 | HealthCap VIII, L.P. | 250,000 0.9752% | $15.00 | $3.75M | -10.92% | |||
| 2020-10-14 | HANSSON JONAS | director | 250,000 0.9752% | $15.00 | $3.75M | -10.92% | ||
| 2020-10-14 | Muralidhar Bali | director | 200,000 0.7802% | $15.00 | $3M | -10.92% | ||
| 2020-10-14 | O'Donnell Niall | director | 250,000 0.9752% | $15.00 | $3.75M | -10.92% |
Insider Historical Profitability
| Novo Holdings A/S | 10 percent owner | 2550000 16.5125% | $0.55 | 2 | 6 | <0.0001% |
| Chaya Moghrabi Dina | director | 2161022 5.3082% | $0.55 | 1 | 0 | <0.0001% |
| Omega Fund VI, L.P. | 2161022 5.3082% | $0.55 | 1 | 0 | <0.0001% | |
| RiverVest Venture Fund III, L.P. | 10 percent owner | 2148281 5.2769% | $0.55 | 1 | 0 | <0.0001% |
| HANSSON JONAS | director | 2033621 4.9953% | $0.55 | 1 | 0 | <0.0001% |
| HealthCap VIII, L.P. | 2033621 4.9953% | $0.55 | 1 | 0 | <0.0001% | |
| Muralidhar Bali | director | 1792518 4.4031% | $0.55 | 1 | 0 | <0.0001% |
| O'Donnell Niall | director | 1326305 3.2579% | $0.55 | 2 | 0 | <0.0001% |
| SIMPSON CAMILLA V | director | 0 0% | $0.55 | 0 | 2 |
Institutional Investor Ownership
| RiverVest | $2.31M | 7.14 | 2.94M | 0% | +$0 | 28.35 | |
| The Carlyle Group | $2.28M | 7.04 | 2.9M | 0% | +$0 | 0.1 | |
| ROCK SPRINGS CAPITAL MANAGEMENT, LP | $2.05M | 6.34 | 2.61M | 0% | +$0 | 0.05 | |
| Aisling Capital Management LP | $947,532.00 | 2.93 | 1.21M | 0% | +$0 | 0.33 | |
| Altium Capital Management Lp | $903,785.00 | 2.79 | 1.15M | New | +$903,785.00 | 0.42 | |
| The Vanguard Group | $678,526.00 | 2.1 | 863,375 | +4.98% | +$32,210.09 | <0.0001 | |
| Sands Capital Ventures LLC | $621,736.00 | 1.91 | 787,007 | 0% | +$0 | 0.15 | |
| Acadian Asset Management | $289,000.00 | 0.9 | 368,831 | New | +$289,000.00 | <0.01 | |
| Renaissance Technologies | $213,000.00 | 0.66 | 271,000 | +46.41% | +$67,515.50 | <0.0001 | |
| Panagora | $199,369.00 | 0.62 | 253,682 | New | +$199,369.00 | <0.01 | |
| ExodusPoint Capital Management, LP | $177,000.00 | 0.55 | 224,833 | New | +$177,000.00 | <0.01 | |
| Awm Investment Company Inc | $157,180.00 | 0.49 | 200,000 | New | +$157,180.00 | 0.02 | |
| Geode Capital Management | $157,343.00 | 0.49 | 200,162 | +19.57% | +$25,750.35 | <0.0001 | |
| BlackRock | $146,136.00 | 0.45 | 185,948 | -28.76% | -$58,995.73 | <0.0001 | |
| Walleye Capital | $140,643.00 | 0.44 | 178,958 | New | +$140,643.00 | <0.0001 | |
| Two Sigma | $96,676.00 | 0.3 | 123,013 | -8.44% | -$8,915.26 | <0.0001 | |
| Millennium Management LLC | $80,337.00 | 0.25 | 102,223 | -79.97% | -$320,818.30 | <0.0001 | |
| Two Sigma Advisers LP | $70,967.00 | 0.22 | 90,300 | -5.54% | -$4,165.28 | <0.0001 | |
| Citadel Advisors LLC | $69,063.00 | 0.21 | 87,877 | -18.81% | -$16,003.39 | <0.0001 | |
| Bridgeway Capital Management | $66,802.00 | 0.21 | 85,000 | 0% | +$0 | <0.01 | |
| Jane Street Capital | $61,728.00 | 0.19 | 78,544 | New | +$61,728.00 | <0.0001 | |
| Lion Point Capital LP | $58,943.00 | 0.18 | 75,000 | New | +$58,943.00 | 0.11 | |
| Northern Trust | $58,907.00 | 0.18 | 74,955 | -22.48% | -$17,079.93 | <0.0001 | |
| Marshall Wace | $57,073.00 | 0.18 | 72,245 | -31.66% | -$26,445.78 | <0.0001 | |
| State Street | $50,612.00 | 0.16 | 64,400 | +3.88% | +$1,891.66 | <0.0001 | |
| Castleview Partners LLC | $46,925.00 | 0.15 | 59,709 | New | +$46,925.00 | 0.03 | |
| Xtx Topco Ltd | $44,597.00 | 0.14 | 56,747 | New | +$44,597.00 | <0.01 | |
| Dimensional Fund Advisors | $36,674.00 | 0.11 | 46,664 | New | +$36,674.00 | <0.0001 | |
| Qube Research & Technologies | $27,717.00 | 0.1 | 39,596 | New | +$27,715.60 | <0.0001 | |
| Susquehanna International Group | $23,348.00 | 0.07 | 29,709 | New | +$23,348.00 | <0.0001 | |
| Simplex Trading Llc | $22,000.00 | 0.07 | 28,100 | New | +$22,000.00 | <0.01 | |
| Bank of America | $20,512.00 | 0.06 | 26,130 | +200,900% | +$20,501.79 | <0.0001 | |
| TWO SIGMA SECURITIES LLC | $20,446.00 | 0.06 | 26,016 | New | +$20,446.00 | <0.0001 | |
| Belvedere Trading LLC | $19,571.00 | 0.06 | 24,900 | New | +$19,571.00 | <0.01 | |
| Balyasny Asset Management Llc | $17,689.00 | 0.06 | 22,508 | New | +$17,689.00 | <0.0001 | |
| Morgan Stanley | $16,916.00 | 0.05 | 21,523 | +909.05% | +$15,239.57 | <0.0001 | |
| OMERS | $12,574.00 | 0.04 | 16,000 | New | +$12,574.00 | <0.0001 | |
| UBS | $12,430.00 | 0.04 | 15,814 | +3,160.62% | +$12,048.78 | <0.0001 | |
| Charles Schwab | $12,016.00 | 0.04 | 15,289 | 0% | +$0 | <0.0001 | |
| Tower Research Capital | $8,982.00 | 0.03 | 11,427 | New | +$8,982.00 | <0.0001 | |
| Group One Trading | $3,096.00 | 0.01 | 3,939 | New | +$3,096.00 | <0.0001 | |
| Caldwell Sutter Capital Inc | $786.00 | <0.01 | 1,000 | 0% | +$0 | <0.0001 | |
| Macquarie Group | $0 | <0.01 | 362 | New | +$0 | <0.0001 | |
| Wells Fargo | $112.00 | <0.01 | 143 | +1.42% | +$1.57 | <0.0001 | |
| Fidelity Investments | $81.00 | <0.01 | 103 | New | +$81.00 | <0.0001 | |
| JPMorgan Chase | $9.00 | <0.01 | 11 | 0% | +$0 | <0.0001 |