Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, gene therapies, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 injection to treat duchenne muscular dystrophy (duchenne) in patients with confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; and VYONDYS 53 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping. The company is also developing AMONDYS 45, a product candidate that uses phosphorodiamidate morpholino oligomer chemistry and exon-skipping technology to skip exon 45 of the dystrophin gene; SRP-5051, a peptide conjugated PMO that binds exon 51 of dystrophin pre-mRNA; SRP-9001, a DMD micro-dystrophin gene therapy program; and SRP-9003, a limb-girdle muscular dystrophies gene therapy program. It has collaboration agreements with F. Hoffman-La Roche Ltd; Nationwide Children's Hospital; Lysogene; Duke University; Genethon; and StrideBio. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.
Over the last 12 months, insiders at Sarepta Therapeutics, Inc. have bought $13.3M and sold $13.31M worth of Sarepta Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Sarepta Therapeutics, Inc. have bought $5.97M and sold $19.62M worth of stock each year.
Highest buying activity among insiders over the last 12 months: Barry Richard (director) — $7.88M. Chambers Michael Andrew (director) — $7.35M. INGRAM DOUGLAS S (President & CEO) — $4M.
The last purchase of 25,225 shares for transaction amount of $2M was made by INGRAM DOUGLAS S (President & CEO) on 2023‑11‑03.
2024-06-25 | Sale | Arif Bilal | Chief Tech Ops Officer | 3,898 0.0043% | $163.23 | $636,271 | -3.87% | |
2024-06-25 | Sale | Brown Ryan Edward | EVP, General Counsel | 38,957 0.0421% | $161.61 | $6.3M | -2.91% | |
2024-06-24 | Sale | Arif Bilal | Chief Tech Ops Officer | 7,859 0.0083% | $163.08 | $1.28M | -3.53% | |
2024-05-02 | Sale | Murray Dallan | Chief Customer Officer | 3,635 0.0041% | $140.00 | $508,900 | -2.32% | |
2024-03-11 | Sale | Boor Kathryn Jean | director | 761 0.0008% | $122.93 | $93,550 | +3.68% | |
2024-03-08 | Sale | Wigzell Hans Lennart Rudolf | director | 15,000 0.0159% | $123.25 | $1.85M | +1.37% | |
2024-03-05 | Sale | Mayo Stephen | director | 3,135 0.0033% | $122.96 | $385,480 | +2.39% | |
2024-03-01 | Sale | Estepan Ian Michael | Chief Financial Officer | 1,200 0.0013% | $128.30 | $153,960 | -2.87% | |
2024-03-01 | Sale | Brown Ryan Edward | EVP, General Counsel | 2,000 0.0021% | $125.34 | $250,680 | -2.87% | |
2024-03-01 | Sale | Arif Bilal | Chief Tech Ops Officer | 2,000 0.0021% | $128.84 | $257,676 | -2.87% | |
2023-11-03 | INGRAM DOUGLAS S | President & CEO | 25,225 0.0275% | $79.36 | $2M | +56.39% | ||
2023-11-03 | Barry Richard | director | 50,000 0.0542% | $78.81 | $3.94M | +56.39% | ||
2023-08-14 | Chambers Michael Andrew | director | 9,979 0.0104% | $109.47 | $1.09M | +6.58% | ||
2023-08-11 | Chambers Michael Andrew | director | 23,686 0.0254% | $108.05 | $2.56M | +10.91% | ||
2023-08-10 | Chambers Michael Andrew | director | 34,867 0.0374% | $106.15 | $3.7M | +13.01% | ||
2023-08-04 | Sale | Wigzell Hans Lennart Rudolf | director | 15,000 0.0163% | $106.72 | $1.6M | +13.68% | |
2022-11-17 | Sale | Mayo Stephen | director | 858 0.0011% | $109.92 | $94,311 | +10.87% | |
2022-08-19 | Chambers Michael Andrew | 40,110 0.0459% | $108.20 | $4.34M | +11.83% | |||
2021-11-24 | Rodino-Klapac Louise | Head of R&D, CSO | 3,780 0.0046% | $79.33 | $299,867 | +1.95% | ||
2021-11-17 | INGRAM DOUGLAS S | President & CEO | 25,026 0.0309% | $79.94 | $2M | +3.14% |
INGRAM DOUGLAS S | President & CEO | 390307 0.4172% | $156.91 | 7 | 0 | +20.1% |
Chambers Michael Andrew | director | 246996 0.264% | $156.91 | 4 | 0 | +11.83% |
Barry Richard | director | 140000 0.1497% | $156.91 | 7 | 3 | +25.36% |
Estepan Ian Michael | Chief Financial Officer | 39114 0.0417% | $156.91 | 0 | 1 | |
Brown Ryan Edward | EVP, General Counsel | 17129 0.0339% | $156.91 | 0 | 2 | |
Arif Bilal | Chief Tech Ops Officer | 17363 0.0286% | $156.91 | 0 | 3 | |
Wigzell Hans Lennart Rudolf | director | 22840 0.0224% | $156.91 | 0 | 9 | |
Murray Dallan | Chief Customer Officer | 18125 0.0192% | $156.91 | 0 | 1 | |
Boor Kathryn Jean | director | 7516 0.008% | $156.91 | 0 | 1 | |
Mayo Stephen | director | 6621 0.0068% | $156.91 | 0 | 2 | |
HAYWOOD GEORGE WEAVER | 8213717 8.7803% | $156.91 | 16 | 0 | <0.0001% | |
EASTBOURNE CAPITAL MANAGEMENT LLC/CA | 10 percent owner | 5659211 6.0496% | $156.91 | 0 | 2 | |
kole Ryszard | Senior Vice President | 1841494 1.9685% | $156.91 | 0 | 4 | |
Hudson Leslie | Former CEO | 384559 0.4111% | $156.91 | 0 | 12 | |
BEHRENS M KATHLEEN | director | 130517 0.1395% | $156.91 | 6 | 2 | +55.61% |
BOYLE J DAVID II | CEO | 70282 0.0751% | $156.91 | 2 | 0 | +60.55% |
Rodino-Klapac Louise | Head of R&D, CSO | 65678 0.0702% | $156.91 | 1 | 0 | +1.95% |
Kaye Edward M. MD | director | 52471 0.0561% | $156.91 | 1 | 4 | |
Price Ben Gil | director | 42830 0.0458% | $156.91 | 10 | 0 | +46.44% |
CHASE ANTHONY R | director | 41744 0.0446% | $156.91 | 9 | 4 | +32.01% |
Howton David T | EVP, General Counsel | 31871 0.0341% | $156.91 | 0 | 8 | |
Mahatme Sandesh | EVP, CFO & CBO | 30179 0.0323% | $156.91 | 1 | 7 | |
Christopher Nishan Garabedian | President and CEO | 29552 0.0316% | $156.91 | 3 | 0 | +35.33% |
Ruff Shamim | SVP, Regulatory Affairs & Qual | 27045 0.0289% | $156.91 | 0 | 5 | |
Aphale Jayant | VP, Technical Operations | 11490 0.0123% | $156.91 | 0 | 2 | |
Bratica Joseph | Principal Financial Officer | 8140 0.0087% | $156.91 | 0 | 3 | |
BONNEY MICHAEL W | director | 7051 0.0075% | $156.91 | 1 | 0 | +39.82% |
HODGMAN JOHN | director | 4333 0.0046% | $156.91 | 0 | 1 | |
Cumbo Alexander | EVP, Chief Commercial Officer | 1867 0.002% | $156.91 | 0 | 4 |
The Vanguard Group | $1.14B | 9.31 | 8.8M | -0.23% | -$2.64M | 0.02 | |
BlackRock | $771.63M | 6.31 | 5.96M | -4.05% | -$32.55M | 0.02 | |
Janus Henderson | $633.17M | 5.18 | 4.89M | -8.5% | -$58.82M | 0.35 | |
Capital International Investors | $623.68M | 5.1 | 4.82M | +1.6% | +$9.84M | 0.13 | |
Avoro Capital Advisors Llc | $562.43M | 4.6 | 4.34M | 0% | +$0 | 6.74 | |
Wellington Management Company | $420.2M | 3.43 | 3.25M | -21.36% | -$114.16M | 0.07 | |
Farallon Capital | $317.63M | 2.6 | 2.45M | +102.76% | +$160.97M | 2.22 | |
State Street | $274.78M | 2.25 | 2.12M | -11.53% | -$35.81M | 0.01 | |
BNY Mellon | $267.6M | 2.19 | 2.07M | -11.27% | -$33.99M | 0.05 | |
T Rowe Price Investment Management Inc | $250.06M | 2.04 | 1.93M | +0.61% | +$1.53M | 0.15 | |
Ecor1 Capital Llc | $248.54M | 2.03 | 1.92M | +130.5% | +$140.71M | 6.32 | |
JPMorgan Chase | $236.73M | 1.94 | 1.83M | +40.39% | +$68.1M | 0.02 | |
Citadel Advisors LLC | $197.18M | 1.61 | 1.52M | +13.43% | +$23.35M | 0.13 | |
Geode Capital Management | $196.87M | 1.61 | 1.52M | +3.46% | +$6.58M | 0.02 | |
Deutsche Bank | $189.07M | 1.55 | 1.46M | -0.98% | -$1.88M | 0.09 | |
Fidelity Investments | $174.59M | 1.43 | 1.35M | -10.52% | -$20.52M | 0.01 | |
Paradigm BioCapital Advisors LP | $139.6M | 1.14 | 1.08M | New | +$139.6M | 5.06 | |
Casdin Capital | $138.39M | 1.13 | 1.07M | +6.21% | +$8.09M | 10.3 | |
Morgan Stanley | $115.02M | 0.94 | 888,433 | -35.63% | -$63.66M | 0.01 | |
Millennium Management LLC | $113.17M | 0.93 | 874,147 | +35.71% | +$29.78M | 0.08 | |
OrbiMed | $90.3M | 0.74 | 697,500 | 0% | +$0 | 1.84 | |
Two Sigma Advisers LP | $85.62M | 0.7 | 661,334 | -6.34% | -$5.8M | 0.15 | |
Bank of America | $84.6M | 0.69 | 653,465 | -46.1% | -$72.36M | 0.01 | |
Boxer Capital, LLC | $84.15M | 0.69 | 650,000 | 0% | +$0 | 4.21 | |
Federated Hermes | $79M | 0.65 | 610,216 | -13.86% | -$12.71M | 0.18 | |
Thrivent Financial For Lutherans | $78.55M | 0.64 | 606,735 | -26.79% | -$28.74M | 0.16 | |
Charles Schwab | $76.31M | 0.62 | 589,439 | +2.26% | +$1.69M | 0.02 | |
Camber Capital Management Lp | $75.73M | 0.62 | 585,000 | -26.88% | -$27.83M | 2.67 | |
Jacobs Levy Equity Management | $75.04M | 0.61 | 579,637 | +26.25% | +$15.6M | 0.34 | |
Nuveen | $70.24M | 0.57 | 542,575 | +1.75% | +$1.21M | 0.02 | |
Perceptive Advisors | $68.05M | 0.56 | 525,683 | +16.33% | +$9.56M | 0.04 | |
Balyasny Asset Management Llc | $65.92M | 0.54 | 509,205 | +2.08% | +$1.34M | 0.18 | |
T. Rowe Price | $65.37M | 0.53 | 504,968 | -31.74% | -$30.39M | 0.01 | |
Adage Capital Partners Gp L L C | $60.85M | 0.5 | 470,000 | New | +$60.85M | 0.11 | |
Royal Bank of Canada | $59.63M | 0.49 | 460,606 | -43.42% | -$45.75M | 0.01 | |
Alkeon Capital Management Llc | $59.4M | 0.49 | 458,845 | +27.87% | +$12.95M | 0.33 | |
Assenagon Asset Management S.A. | $56.66M | 0.46 | 437,690 | +14.05% | +$6.98M | 0.15 | |
Northern Trust | $55.77M | 0.46 | 430,823 | -1.54% | -$872,948.79 | 0.01 | |
Voloridge Investment Management, LLC | $55.73M | 0.46 | 430,469 | +20.06% | +$9.31M | 0.13 | |
Scotiabank | $54.57M | 0.45 | 421,536 | -20.28% | -$13.89M | 0.11 | |
Logos Global Management Lp | $51.78M | 0.42 | 400,000 | New | +$51.78M | 5.56 | |
Amundi | $46.42M | 0.42 | 398,286 | -0.27% | -$125,990.55 | 0.02 | |
Renaissance Technologies | $50.52M | 0.41 | 390,278 | -30.68% | -$22.36M | 0.08 | |
Barclays | $49.9M | 0.41 | 385,480 | -12.97% | -$7.43M | 0.02 | |
Fiera Capital | $47.52M | 0.39 | 367,039 | +5.41% | +$2.44M | 0.14 | |
Two Sigma | $44.36M | 0.36 | 342,682 | +13.34% | +$5.22M | 0.08 | |
Voya Investment Management LLC | $43.71M | 0.36 | 337,634 | +11.88% | +$4.64M | 0.05 | |
ROCK SPRINGS CAPITAL MANAGEMENT, LP | $42.41M | 0.35 | 327,600 | 0% | +$0 | 1.08 | |
AllianceBernstein | $41.2M | 0.34 | 318,237 | +24.36% | +$8.07M | 0.02 | |
Mizuho Markets Americas Llc | $37.65M | 0.31 | 290,800 | -4.86% | -$1.92M | 1.03 |