| $350M | ||
| $172M | ||
| $127M | ||
| $109M | ||
| $107M | ||
| $100M |
Buys | $0 | 0 | 0 |
Sells | $10,589,832 | 11 | 100 |
| KAPLAN GILLA | director | 0 | $0 | 1 | $528,506 | $-528,506 |
| Bensen Daniel | Chief Operating Officer | 0 | $0 | 8 | $4.81M | $-4.81M |
| MORE ROBERT J | director | 0 | $0 | 2 | $5.25M | $-5.25M |
Tyra Biosciences, Inc. is a preclinical biopharmaceutical company focused on innovating treatments to tackle tumor resistance and enhance patient outcomes in oncology. Its flagship product candidate, TYRA-300, is a highly selective inhibitor of fibroblast growth factor receptor (FGFR)3, specifically engineered for the treatment of muscle-invasive bladder cancer. Beyond this, the company is advancing a pipeline of programs addressing other critical conditions, including FGFR2-related intrahepatic cholangiocarcinoma, FGFR3-associated achondroplasia, REarranged during transfection (RET) kinase aberrations, and various FGFR4-driven cancers. Tyra also leverages its proprietary SNAP platform, designed to accelerate structural drug design through an iterative molecular 'snapshot' approach. Founded in 2018, Tyra Biosciences maintains its headquarters in Carlsbad, California.
Over the last 12 months, insiders at Tyra Biosciences, Inc. have bought $0 and sold $10.59M worth of Tyra Biosciences, Inc. stock.
On average, over the past 5 years, insiders at Tyra Biosciences, Inc. have bought $54.29M and sold $8.97M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 11,813 shares for transaction amount of $119,666 was made by RA CAPITAL MANAGEMENT, L.P. () on 2025‑06‑16.
| 2026-03-25 | Sale | KAPLAN GILLA | director | 14,295 0.0268% | $36.97 | $528,506 | -12.99% | |
| 2026-02-12 | Sale | Bensen Daniel | Chief Discovery Officer | 8,000 0.0169% | $32.87 | $262,965 | +11.92% | |
| 2026-01-12 | Sale | Bensen Daniel | Chief Discovery Officer | 8,000 0.0149% | $28.52 | $228,186 | +11.02% | |
| 2025-12-19 | Sale | MORE ROBERT J | director | 10,000 0.0184% | $25.00 | $250,000 | +23.09% | |
| 2025-12-12 | Sale | Bensen Daniel | Chief Discovery Officer | 8,000 0.015% | $22.64 | $181,159 | +37.76% | |
| 2025-11-21 | Sale | MORE ROBERT J | director | 246,871 0.4436% | $20.25 | $5M | +46.43% | |
| 2025-11-19 | Sale | Bensen Daniel | Chief Operating Officer | 49,956 0.0919% | $16.32 | $815,297 | +85.89% | |
| 2025-11-18 | Sale | Bensen Daniel | Chief Operating Officer | 75,633 0.142% | $16.07 | $1.22M | +92.52% | |
| 2025-11-17 | Sale | Bensen Daniel | Chief Operating Officer | 20,072 0.0383% | $16.18 | $324,798 | +94.15% | |
| 2025-11-14 | Sale | Bensen Daniel | Chief Operating Officer | 110,228 0.2122% | $16.02 | $1.77M | +96.19% | |
| 2025-11-13 | Sale | Bensen Daniel | Chief Operating Officer | 1,111 0.0021% | $16.00 | $17,780 | +97.82% | |
| 2025-06-18 | Sale | KAPLAN GILLA | director | 9,568 0.0185% | $9.78 | $93,596 | +141.79% | |
| 2025-06-17 | Sale | KAPLAN GILLA | director | 10 <0.0001% | $10.35 | $104 | +137.85% | |
| 2025-06-16 | Sale | KAPLAN GILLA | director | 6,814 0.013% | $10.38 | $70,726 | +123.09% | |
| 2025-06-16 | RA CAPITAL MANAGEMENT, L.P. | 11,813 0.022% | $10.13 | $119,666 | +123.09% | |||
| 2025-06-13 | Sale | KAPLAN GILLA | director | 15,000 0.0279% | $10.31 | $154,583 | +116.83% | |
| 2025-06-13 | RA CAPITAL MANAGEMENT, L.P. | 120,167 0.2214% | $10.20 | $1.23M | +116.83% | |||
| 2025-06-12 | Sale | KAPLAN GILLA | director | 30,000 0.0564% | $10.31 | $309,255 | +118.78% | |
| 2025-06-12 | RA CAPITAL MANAGEMENT, L.P. | 31,307 0.0582% | $10.20 | $319,331 | +118.78% | |||
| 2025-06-09 | RA CAPITAL MANAGEMENT, L.P. | 186,850 0.3495% | $10.19 | $1.9M | +116.96% |
| MORE ROBERT J | director | 3823425 6.4084% | $109.54M | 1 | 2 | <0.0001% |
| Bensen Daniel | Chief Discovery Officer | 146981 0.2464% | $4.21M | 0 | 49 | |
| KAPLAN GILLA | director | 28231 0.0473% | $808,818.15 | 0 | 6 | |
| RA CAPITAL MANAGEMENT, L.P. | 10259291 17.1954% | $293.93M | 8 | 0 | +79.87% | |
| Boxer Capital, LLC | 10 percent owner | 6448359 10.808% | $184.75M | 2 | 0 | <0.0001% |
| Alta Partners NextGen Fund II Management, LLC | 10 percent owner | 4080296 6.8389% | $116.9M | 1 | 0 | <0.0001% |
| Harris Todd | President and CEO | 1355927 2.2726% | $38.85M | 0 | 31 | |
| Cormorant Asset Management, LP | 1069932 1.7933% | $30.65M | 1 | 0 | <0.0001% | |
| Kjellson Nina S | director | 443885 0.744% | $12.72M | 0 | 13 | |
| MVA Investors, LLC | 10 percent owner | 22527 0.0378% | $645,398.55 | 0 | 2 | |
| Fuhrman Alan | Chief Financial Officer | 12849 0.0215% | $368,123.85 | 1 | 0 | <0.0001% |
$8,217,280 | 112 | 46.33% | $1.68B | |
$61,893,001 | 38 | 19.63% | $1.47B | |
$530,111,731 | 35 | 8.69% | $1.57B | |
$28,907,358 | 35 | 41.41% | $1.97B | |
$4,431,947 | 22 | 36.10% | $1.6B | |
$135,656,796 | 20 | 30.67% | $1.68B | |
$24,007,605 | 16 | -20.65% | $1.79B | |
Tyra Biosciences, Inc. (TYRA) | $108,588,651 | 14 | 29.35% | $1.71B |
$48,220,484 | 14 | 2.13% | $1.78B | |
$81,819,942 | 13 | -52.16% | $1.49B | |
$3,101,788 | 13 | 41.97% | $1.82B | |
$278,247,340 | 12 | 58.08% | $1.92B | |
$94,976,497 | 10 | -10.72% | $1.92B | |
$4,623,072 | 7 | 11.07% | $1.51B | |
$47,238,722 | 7 | -23.48% | $1.78B | |
$1,011,808 | 4 | 52.60% | $1.68B | |
$103,599,972 | 2 | -36.81% | $1.9B | |
$33,624,000 | 2 | -50.37% | $1.52B | |
$23,993,224 | 1 | 9.82% | $1.84B |
| Increased Positions | 72 | +55.81% | 6M | +10.45% |
| Decreased Positions | 53 | -41.09% | 4M | -7.98% |
| New Positions | 30 | New | 3M | New |
| Sold Out Positions | 14 | Sold Out | 783,658 | Sold Out |
| Total Postitions | 148 | +14.73% | 57M | +2.47% |
| Ra Capital Management, L.P. | $326,801.00 | 23.02% | 12.2M | 0 | 0% | 2025-09-30 |
| Alta Partners Management Company, L.P. | $109,311.00 | 7.7% | 4.08M | 0 | 0% | 2025-09-30 |
| Nextech Invest, Ltd. | $108,657.00 | 7.65% | 4.06M | 0 | 0% | 2025-09-30 |
| Bvf Inc/Il | $97,778.00 | 6.89% | 3.65M | -294,400 | -7.46% | 2025-09-30 |
| Canaan Partners Xi Llc | $96,661.00 | 6.81% | 3.61M | 0 | 0% | 2025-09-30 |
| Commodore Capital Lp | $90,416.00 | 6.37% | 3.38M | +275,000 | +8.87% | 2025-09-30 |
| Tcg Crossover Management, Llc | $77,640.00 | 5.47% | 2.9M | 0 | 0% | 2025-09-30 |
| Janus Henderson Group Plc | $77,016.00 | 5.42% | 2.87M | +18,514 | +0.65% | 2025-09-30 |
| Vestal Point Capital, Lp | $64,966.00 | 4.58% | 2.42M | -230,000 | -8.66% | 2025-09-30 |
| Kynam Capital Management, Lp | $62,421.00 | 4.4% | 2.33M | 0 | 0% | 2025-09-30 |