Vigil Neuroscience, Inc., a microglia-focused company, engages in the development of disease-modifying therapeutics for patients, caregivers, and families affected by rare and common neurodegenerative diseases. Its lead product candidate is VGL101, a fully human monoclonal antibody (mAb) that is designed to activate triggering receptor expressed on myeloid cells 2 (TREM2) which is in Phase I for the treatment of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia, as well as for the treatment of cerebral adrenoleukodystrophy and alzheimer's disease. The company also develops a small molecule TREM2 agonist suitable for oral delivery to treat common neurodegenerative diseases associated with microglial dysfunction. Vigil Neuroscience, Inc. was incorporated in 2020 and is headquartered in Cambridge, Massachusetts.
Over the last 12 months, insiders at Vigil Neuroscience, Inc. have bought $15,000 and sold $0 worth of Vigil Neuroscience, Inc. stock.
On average, over the past 5 years, insiders at Vigil Neuroscience, Inc. have bought $35.35M and sold $4,200 worth of stock each year.
Highest buying activity among insiders over the last 12 months: Magovcevic-Liebisch Ivana (President and CEO) — $15,000.
The last purchase of 4,000 shares for transaction amount of $15,000 was made by Magovcevic-Liebisch Ivana (President and CEO) on 2023‑11‑20.
2023-11-20 | Magovcevic-Liebisch Ivana | President and CEO | 4,000 0.0114% | $3.75 | $15,000 | -11.31% | ||
2022-11-18 | Sale | Papapetropoulos Spyros | Chief Medical Officer | 300 0.001% | $14.00 | $4,200 | -27.38% | |
2022-05-16 | Thorp Clay | 14,893 0.0551% | $2.97 | $44,189 | +235.79% | |||
2022-05-05 | Thackaberry Evan | SVP, Head of Early Development | 1,500 0.0064% | $4.00 | $6,000 | +185.03% | ||
2022-05-03 | Ziolkowski Jennifer Lynn | Chief Financial Officer | 4,000 0.0149% | $3.77 | $15,098 | +163.16% | ||
2022-05-03 | Verni Christopher | General Counsel | 4,000 0.0148% | $3.77 | $15,074 | +163.16% | ||
2022-05-03 | Papapetropoulos Spyros | Chief Medical Officer | 4,000 0.0134% | $3.40 | $13,591 | +163.16% | ||
2022-05-02 | Magovcevic-Liebisch Ivana | President and CEO | 4,000 0.0141% | $3.61 | $14,439 | +160.99% | ||
2022-03-28 | Thorp Clay | 3,000 0.0114% | $7.20 | $21,604 | +25.92% | |||
2022-01-11 | Vitorovic Stefan | director | 1.68M 7.4164% | $14.00 | $23.45M | -24.96% | ||
2022-01-11 | Vida Ventures GP III, L.L.C. | 10 percent owner | 1.68M 7.4164% | $14.00 | $23.45M | -24.96% | ||
2022-01-11 | Booth Bruce | director | 535,000 2.3688% | $14.00 | $7.49M | -24.96% | ||
2022-01-11 | Atlas Venture Fund XII, L.P. | 10 percent owner | 535,000 2.3688% | $14.00 | $7.49M | -24.96% | ||
2022-01-11 | Thorp Clay | director | 265,000 1.1733% | $14.00 | $3.71M | -24.96% | ||
2022-01-11 | Northpond Ventures GP, LLC | 10 percent owner | 355,000 1.5718% | $14.00 | $4.97M | -24.96% |
Magovcevic-Liebisch Ivana | President and CEO | 207687 0.5789% | $3.78 | 2 | 0 | +160.99% |
Vitorovic Stefan | director | 5004393 13.9501% | $3.78 | 1 | 0 | <0.0001% |
Vida Ventures GP III, L.L.C. | 10 percent owner | 5004393 13.9501% | $3.78 | 1 | 0 | <0.0001% |
Booth Bruce | director | 4808896 13.4052% | $3.78 | 1 | 0 | <0.0001% |
Atlas Venture Fund XII, L.P. | 10 percent owner | 4808896 13.4052% | $3.78 | 1 | 0 | <0.0001% |
Thorp Clay | 1556030 4.3376% | $3.78 | 3 | 0 | +78.92% | |
Northpond Ventures GP, LLC | 10 percent owner | 1382978 3.8552% | $3.78 | 1 | 0 | <0.0001% |
Verni Christopher | General Counsel | 4000 0.0112% | $3.78 | 1 | 0 | +163.16% |
Papapetropoulos Spyros | Chief Medical Officer | 4000 0.0112% | $3.78 | 1 | 1 | +163.16% |
Ziolkowski Jennifer Lynn | Chief Financial Officer | 4000 0.0112% | $3.78 | 1 | 0 | +163.16% |
Thackaberry Evan | SVP, Head of Early Development | 1500 0.0042% | $3.78 | 1 | 0 | +185.03% |
Atlas Venture Life Science Advisors Llc | $19.9M | 15.53 | 5.84M | 0% | +$0 | 1.9 | |
Northpond Partners LLC | $14.37M | 11.21 | 4.21M | 0% | +$0 | 0.32 | |
Citadel Advisors LLC | $7.39M | 5.76 | 2.17M | +0.18% | +$13,329.69 | 0.01 | |
Bvf Inc Il | $6.18M | 4.83 | 1.81M | 0% | +$0 | 0.05 | |
Artal Group S A | $6.18M | 4.82 | 1.81M | 0% | +$0 | 0.03 | |
Sphera Fund | $5.9M | 4.6 | 1.73M | +223.37% | +$4.08M | 0.98 | |
Deep Track Capital Lp | $5.44M | 4.24 | 1.59M | 0% | +$0 | 0.03 | |
683 Capital Management Llc | $3.39M | 2.65 | 994,900 | New | +$3.39M | 0.38 | |
Deerfield Management | $3.34M | 2.61 | 980,311 | -16.46% | -$658,853.02 | 0.07 | |
The Vanguard Group | $3.05M | 2.38 | 894,473 | +11.92% | +$324,891.06 | <0.0001 | |
BlackRock | $2.99M | 2.33 | 877,032 | -4.58% | -$143,561.04 | <0.0001 | |
Pivotal Bioventure Partners Investment Advisor Llc | $1.91M | 1.49 | 560,595 | 0% | +$0 | 1.4 | |
ROCK SPRINGS CAPITAL MANAGEMENT, LP | $1.61M | 1.26 | 471,958 | 0% | +$0 | 0.04 | |
OrbiMed | $1.53M | 1.19 | 448,891 | 0% | +$0 | 0.03 | |
Geode Capital Management | $1.14M | 0.89 | 334,242 | +5.93% | +$63,786.95 | <0.0001 | |
Arrowmark Colorado Holdings Llc | $987,059.00 | 0.77 | 289,460 | 0% | +$0 | <0.01 | |
State Street | $975,475.00 | 0.76 | 286,063 | +0.98% | +$9,452.52 | <0.0001 | |
Ensign Peak Advisors Inc | $779,778.00 | 0.61 | 228,674 | 0% | +$0 | <0.01 | |
Northern Trust | $473,035.00 | 0.37 | 138,720 | -1.9% | -$9,142.21 | <0.0001 | |
Barclays | $386,000.00 | 0.3 | 113,036 | -8.69% | -$36,740.28 | <0.0001 | |
DAFNA Capital Management, LLC | $244,889.00 | 0.19 | 71,815 | 0% | +$0 | 0.06 | |
Citigroup | $229,527.00 | 0.18 | 67,310 | +0.99% | +$2,243.78 | <0.0001 | |
Renaissance Technologies | $204,000.00 | 0.16 | 59,964 | New | +$204,000.00 | <0.0001 | |
Bridgeway Capital Management | $197,657.00 | 0.15 | 57,964 | -56.41% | -$255,749.69 | <0.01 | |
BNY Mellon | $156,007.00 | 0.12 | 45,750 | -5.65% | -$9,336.55 | <0.0001 | |
Two Sigma | $153,443.00 | 0.12 | 44,998 | +186.1% | +$99,810.58 | <0.0001 | |
Charles Schwab | $143,111.00 | 0.11 | 41,968 | 0% | +$0 | <0.0001 | |
PEAK6 Investments, LP | $141,467.00 | 0.11 | 41,486 | 0% | +$0 | 0.01 | |
Bank of Montreal | $234,911.00 | 0.09 | 33,368 | New | +$234,911.00 | <0.0001 | |
Millennium Management LLC | $112,970.00 | 0.09 | 33,129 | New | +$112,970.00 | <0.0001 | |
Nuveen | $91,524.00 | 0.07 | 26,840 | 0% | +$0 | <0.0001 | |
Two Sigma Advisers LP | $82,181.00 | 0.06 | 24,100 | New | +$82,181.00 | <0.0001 | |
Morgan Stanley | $79,665.00 | 0.06 | 23,362 | -57.46% | -$107,593.10 | <0.0001 | |
Prelude Capital | $69,486.00 | 0.05 | 20,377 | New | +$69,486.00 | 0.01 | |
Connor Clark & Lunn Investment Management Ltd | $65,397.00 | 0.05 | 19,178 | New | +$65,397.00 | <0.0001 | |
Bank of America | $64,582.00 | 0.05 | 18,939 | -34.77% | -$34,423.96 | <0.0001 | |
Goldman Sachs | $62,195.00 | 0.05 | 18,239 | -78.57% | -$227,996.05 | <0.0001 | |
RhumbLine Advisers | $61,212.00 | 0.05 | 17,953 | +3.96% | +$2,332.14 | <0.0001 | |
UBS | $55,075.00 | 0.04 | 16,151 | New | +$55,075.00 | <0.0001 | |
New York State Common Retirement Fund | $35,000.00 | 0.03 | 10,140 | 0% | +$0 | <0.0001 | |
American International Group | $27,004.00 | 0.02 | 7,919 | -0.85% | -$231.88 | <0.0001 | |
Ohio Strs | $26,000.00 | 0.02 | 7,700 | -6.1% | -$1,688.31 | <0.0001 | |
JPMorgan Chase | $24,266.00 | 0.02 | 7,116 | -31.68% | -$11,249.79 | <0.0001 | |
Wells Fargo | $19,284.00 | 0.02 | 5,655 | +14.8% | +$2,485.95 | <0.0001 | |
Tower Research Capital | $19,740.00 | 0.02 | 5,789 | +100.8% | +$9,909.21 | <0.0001 | |
Legal & General | $5,268.00 | <0.01 | 1,554 | 0% | +$0 | <0.0001 | |
Ameritas Investment Partners Inc | $4,525.00 | <0.01 | 1,327 | 0% | +$0 | <0.0001 | |
Fidelity Investments | $5,627.00 | <0.01 | 1,650 | -98.83% | -$474,659.62 | <0.0001 | |
Amalgamated Bank | $2,000.00 | <0.01 | 542 | -61.34% | -$3,173.43 | <0.0001 | |
Royal Bank of Canada | $1,000.00 | <0.01 | 367 | -91.44% | -$10,681.20 | <0.0001 |