VYNE Therapeutics Inc. (VYNE)
Largest Insider Buys in Sector
VYNE Stock Price History Chart
VYNE Stock Performance
About VYNE Therapeutics Inc.
VYNE Therapeutics Inc., a pharmaceutical company, focuses on developing various therapeutics for the treatment of immuno-inflammatory conditions. The company develops FCD105, a topical combination foam that has completed Phase III clinical trials for the treatment of moderate-to-severe acne vulgaris; and FMX114, a combination of tofacitinib, which is in Phase IIa preclinical trial for the treatment of mild-to-moderate atopic dermatitis. It is also developing VYN201, a bromodomain and extra-terminal (BET) inhibitor for various immuno-inflammatory diseases, including skin diseases; and VYN202, BET inhibitor compounds that are selective for bromodomain 2. The company was formerly known as Menlo Therapeutics Inc. and changed its name to VYNE Therapeutics Inc. in September 2020. VYNE Therapeutics Inc. was founded in 2003 and is based in Bridgewater, New Jersey.
Insider Activity of VYNE Therapeutics Inc.
Over the last 12 months, insiders at VYNE Therapeutics Inc. have bought $50,778 and sold $0 worth of VYNE Therapeutics Inc. stock.
On average, over the past 5 years, insiders at VYNE Therapeutics Inc. have bought $5.18M and sold $2.66M worth of stock each year.
Highest buying activity among insiders over the last 12 months: LEPORE PATRICK G (director) — $101,556.
The last purchase of 13,000 shares for transaction amount of $50,778 was made by LEPORE PATRICK G (director) on 2023‑11‑15.
List of Insider Buy and Sell Transactions, VYNE Therapeutics Inc.
| 2023-11-15 | LEPORE PATRICK G | director | 13,000 0.3748% | $3.91 | $50,778 | -44.13% | ||
| 2021-11-30 | LEPORE PATRICK G | director | 12,500 0.024% | $1.02 | $12,699 | -55.58% | ||
| 2021-08-25 | LEPORE PATRICK G | director | 12,500 0.0243% | $1.60 | $20,000 | -62.28% | ||
| 2021-08-16 | Sale | PERCEPTIVE ADVISORS LLC | 10 percent owner | 250,000 0.4697% | $1.74 | $435,000 | -64.78% | |
| 2021-08-13 | Sale | PERCEPTIVE ADVISORS LLC | 10 percent owner | 250,000 0.4967% | $1.84 | $460,000 | -64.61% | |
| 2021-08-12 | Sale | PERCEPTIVE ADVISORS LLC | 10 percent owner | 338,897 0.7299% | $2.23 | $755,740 | -68.34% | |
| 2021-05-26 | LEPORE PATRICK G | director | 12,500 0.0241% | $3.60 | $44,958 | -68.32% | ||
| 2021-05-06 | Sale | PERCEPTIVE ADVISORS LLC | 10 percent owner | 1M 2.0052% | $3.67 | $3.67M | -65.17% | |
| 2021-03-15 | LEPORE PATRICK G | director | 12,500 0.0259% | $7.41 | $92,563 | -79.34% | ||
| 2021-01-28 | PERCEPTIVE ADVISORS LLC | 10 percent owner | 4.22M 2.2941% | $2.37 | $10M | -69.62% | ||
| 2020-12-03 | LEPORE PATRICK G | director | 100,000 0.078% | $1.71 | $170,850 | -46.15% | ||
| 2020-09-08 | Domzalski David | President and CEO | 150,000 0.084% | $1.38 | $207,135 | +10.54% | ||
| 2020-09-08 | Saik Andrew | Chief Financial Officer | 80,000 0.0474% | $1.46 | $116,960 | +10.54% | ||
| 2020-06-09 | PERCEPTIVE ADVISORS LLC | 10 percent owner | 5.41M 3.4508% | $1.85 | $10M | -19.14% | ||
| 2018-07-24 | Sale | Presidio Partners 2007 GP, L.P. | 1M 4.3407% | $7.65 | $7.65M | -11.34% | ||
| 2018-01-25 | Remeditex Ventures LLC | 10 percent owner | 200,000 0.6735% | $17.00 | $3.4M | -71.72% | ||
| 2018-01-25 | venBio Global Strategic Fund II L.P. | 10 percent owner | 530,000 1.7848% | $17.00 | $9.01M | -71.72% | ||
| 2018-01-25 | Vivo Capital VIII, LLC | 10 percent owner | 588,236 1.9809% | $17.00 | $10M | -71.72% | ||
| 2018-01-25 | Cha Albert | director | 588,236 1.9809% | $17.00 | $10M | -71.72% |
Insider Historical Profitability
| LEPORE PATRICK G | director | 36472 0.2613% | $1.60 | 6 | 0 | <0.0001% |
| PERCEPTIVE ADVISORS LLC | 10 percent owner | 4935057 35.3582% | $1.60 | 2 | 4 | <0.0001% |
| Remeditex Ventures LLC | 10 percent owner | 1582854 11.3407% | $1.60 | 1 | 0 | |
| Domzalski David | President and CEO | 1315966 9.4285% | $1.60 | 1 | 0 | +10.54% |
| Saik Andrew | Chief Financial Officer | 340000 2.436% | $1.60 | 1 | 0 | +10.54% |
| venBio Global Strategic Fund II L.P. | 10 percent owner | 265000 1.8986% | $1.60 | 1 | 0 | |
| Cha Albert | director | 258432 1.8516% | $1.60 | 1 | 0 | |
| Vivo Capital VIII, LLC | 10 percent owner | 258432 1.8516% | $1.60 | 1 | 0 | |
| Presidio Partners 2007 GP, L.P. | 48910 0.3504% | $1.60 | 0 | 1 |
Institutional Investor Ownership
| Eventide Asset Management | $3.13M | 9.6 | 1.39M | 0% | +$0 | 0.05 | |
| Cormorant Asset Management Lp | $4.28M | 9.6 | 1.39M | 0% | +$0 | 0.2 | |
| Citadel Advisors LLC | $3.63M | 8.13 | 1.18M | 0% | +$0 | <0.01 | |
| Dsc Advisors L P | $2.14M | 4.79 | 696,465 | 0% | +$0 | 3.46 | |
| Parkman Healthcare Partners Llc | $2.14M | 4.79 | 696,470 | 0% | +$0 | 0.26 | |
| Palo Alto Investors Lp | $1.37M | 3.07 | 445,434 | 0% | +$0 | 0.15 | |
| Alphacentric Advisors Llc | $1.37M | 3.06 | 445,000 | -33.4% | -$685,073.57 | 0.87 | |
| Schonfeld Group | $674,786.00 | 1.51 | 219,800 | New | +$674,786.00 | 0.01 | |
| Royal Bank of Canada | $538,000.00 | 1.21 | 175,372 | +13,763.4% | +$534,119.28 | <0.0001 | |
| Geode Capital Management | $327,823.00 | 0.74 | 106,775 | +13.18% | +$38,169.00 | <0.0001 | |
| Prelude Capital | $290,422.00 | 0.65 | 94,600 | -19.9% | -$72,145.00 | 0.02 | |
| Silverarc Capital Management Llc | $265,196.00 | 0.6 | 86,383 | New | +$265,196.00 | 0.08 | |
| Renaissance Technologies | $247,000.00 | 0.56 | 80,576 | +73.75% | +$104,837.67 | <0.0001 | |
| The Vanguard Group | $213,773.00 | 0.48 | 69,633 | +40.44% | +$61,556.48 | <0.0001 | |
| Susquehanna International Group | $185,192.00 | 0.42 | 60,323 | 0% | +$0 | <0.0001 | |
| BlackRock | $136,977.00 | 0.31 | 44,618 | -5.66% | -$8,224.51 | <0.0001 | |
| Northern Trust | $113,440.00 | 0.25 | 36,951 | 0% | +$0 | <0.0001 | |
| Staley Capital Advisers, Inc. | $111,969.00 | 0.25 | 36,472 | 0% | +$0 | 0.01 | |
| Virtu Financial Llc | $50,000.00 | 0.11 | 16,199 | New | +$50,000.00 | <0.01 | |
| State Street | $35,812.00 | 0.08 | 11,665 | 0% | +$0 | <0.0001 | |
| Millennium Management LLC | $33,739.00 | 0.08 | 10,990 | -36.38% | -$19,288.64 | <0.0001 | |
| Bank of America | $6,714.00 | 0.02 | 2,187 | -21.47% | -$1,835.84 | <0.0001 | |
| Morgan Stanley | $5,735.00 | 0.01 | 1,868 | 0% | +$0 | <0.0001 | |
| Tower Research Capital | $3,810.00 | 0.01 | 1,241 | +57.09% | +$1,384.62 | <0.0001 | |
| JPMorgan Chase | $520.00 | <0.01 | 169 | +15.75% | +$70.77 | <0.0001 | |
| Wells Fargo | $535.00 | <0.01 | 174 | +1.16% | +$6.15 | <0.0001 | |
| Russell Investments Group Ltd | $574.00 | <0.01 | 187 | 0% | +$0 | <0.0001 | |
| UBS | $49.00 | <0.01 | 16 | -98.11% | -$2,541.88 | <0.0001 | |
| Cornerstone Planning Group Llc | $6.00 | <0.01 | 2 | New | +$6.00 | <0.0001 |