Zymeworks Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer. The company's lead product candidates include zanidatamab, a novel bispecific antibody that is in Phase 1 and Phase 2 clinical trials for the treatment of biliary tract, gastroesophageal adenocarcinomas, breast, and colorectal cancer; and ZW49, a biparatopic anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate that is in Phase 1 clinical trial for the treatment of advanced or metastatic HER2-expressing tumors. The company has strategic partnerships with Merck Sharp & Dohme Research Ltd.; Eli Lilly and Company; Bristol-Myers Squibb company; GlaxoSmithKline Intellectual Property Development Ltd.; Daiichi Sankyo Co., Ltd.; Janssen Biotech, Inc.; BeiGene, Ltd.; and Exelixis, Inc. It also has licensing and research collaboration with LEO Pharma A/S to research, develop, and commercialize bispecific antibodies; and Iconic Therapeutics, Inc. Zymeworks Inc. was incorporated in 2003 and is headquartered in Vancouver, Canada.
Over the last 12 months, insiders at Zymeworks Inc. have bought $0 and sold $436,288 worth of Zymeworks Inc. stock.
On average, over the past 5 years, insiders at Zymeworks Inc. have bought $16.77M and sold $3.09M worth of stock each year.
There was no buying activity among insiders over the last 12 months.
The last purchase of 3,350,000 shares for transaction amount of $27.2M was made by EcoR1 Capital, LLC (10 percent owner) on 2023‑06‑16.
2024-01-08 | Sale | Galbraith Kenneth | Chair & CEO | 5,706 0.0079% | $11.22 | $63,996 | -16.26% | |
2024-01-08 | Sale | Moore Paul Andrew | Chief Scientific Officer | 2,339 0.0033% | $11.22 | $26,233 | -16.26% | |
2024-01-08 | Sale | Astle Christopher | SVP & Chief Financial Officer | 1,431 0.002% | $11.22 | $16,050 | -16.26% | |
2024-01-05 | Sale | Galbraith Kenneth | Chair & CEO | 18,198 0.0262% | $10.65 | $193,849 | -8.70% | |
2024-01-05 | Sale | Moore Paul Andrew | Chief Scientific Officer | 7,460 0.0107% | $10.65 | $79,465 | -8.70% | |
2024-01-05 | Sale | Astle Christopher | SVP & Chief Financial Officer | 4,563 0.0066% | $10.65 | $48,606 | -8.70% | |
2023-12-11 | Sale | Astle Christopher | SVP & Chief Financial Officer | 886 0.0013% | $9.13 | $8,089 | +5.63% | |
2023-06-16 | EcoR1 Capital, LLC | 10 percent owner | 3.35M 5.0195% | $8.12 | $27.2M | +7.27% | ||
2023-03-28 | EcoR1 Capital, LLC | 10 percent owner | 200,000 0.2981% | $8.00 | $1.6M | +6.44% | ||
2023-03-10 | Sale | Klompas Neil A | President & COO | 2,977 0.0044% | $7.83 | $23,298 | +6.56% | |
2023-01-20 | EcoR1 Capital, LLC | director | 163,400 0.2428% | $9.88 | $1.62M | -16.45% | ||
2023-01-19 | EcoR1 Capital, LLC | director | 144,100 0.2124% | $9.49 | $1.37M | -13.66% | ||
2023-01-18 | EcoR1 Capital, LLC | director | 203,000 0.3051% | $10.00 | $2.03M | -16.43% | ||
2023-01-17 | EcoR1 Capital, LLC | director | 440,000 0.6486% | $9.80 | $4.31M | -16.43% | ||
2023-01-13 | EcoR1 Capital, LLC | director | 342,100 0.5024% | $9.81 | $3.35M | -16.78% | ||
2023-01-11 | EcoR1 Capital, LLC | director | 106,300 0.1527% | $7.87 | $836,911 | +1.43% | ||
2023-01-10 | EcoR1 Capital, LLC | director | 920,000 1.3565% | $7.65 | $7.04M | +7.02% | ||
2022-11-10 | Sale | Josephson Neil | Chief Medical Officer | 2,475 0.0037% | $8.10 | $20,045 | -2.32% | |
2022-10-13 | Redmile Group, LLC | 10 percent owner | 30,481 0.0481% | $5.03 | $153,435 | +63.80% | ||
2022-03-10 | Sale | Klompas Neil A | Chief Operating Officer | 2,979 0.0048% | $6.88 | $20,496 | -6.14% |
Galbraith Kenneth | Chair & CEO | 23762 0.0339% | $8.40 | 0 | 2 | |
Moore Paul Andrew | Chief Scientific Officer | 7367 0.0105% | $8.40 | 0 | 2 | |
Astle Christopher | SVP & Chief Financial Officer | 6503 0.0093% | $8.40 | 0 | 3 | |
EcoR1 Capital, LLC | 10 percent owner | 13437473 19.1958% | $8.40 | 9 | 0 | <0.0001% |
Redmile Group, LLC | 10 percent owner | 6075918 8.6796% | $8.40 | 1 | 0 | +63.8% |
LILLY ELI & CO | 10 percent owner | 2898647 4.1408% | $8.40 | 0 | 17 | |
Tehrani Ali | Chief Executive Officer | 260325 0.3719% | $8.40 | 1 | 6 | +12.44% |
Polverino Anthony J. | Chief Scientific Officer | 30979 0.0443% | $8.40 | 0 | 1 | |
Klompas Neil A | President & COO | 17032 0.0243% | $8.40 | 0 | 5 | |
Josephson Neil | Chief Medical Officer | 14449 0.0206% | $8.40 | 1 | 1 | <0.0001% |
Cox Troy | director | 7500 0.0107% | $8.40 | 1 | 0 | <0.0001% |
HAUSMAN DIANA | Chief Medical Officer | 5377 0.0077% | $8.40 | 0 | 5 | |
O'Driscoll Kathryn | Chief People Officer | 5003 0.0071% | $8.40 | 0 | 2 | |
Priour James | Chief Commercial Officer | 2003 0.0029% | $8.40 | 0 | 1 | |
Poon David Kai Yuen | See Remarks | 0 0% | $8.40 | 0 | 1 |
Ecor1 Capital Llc | $141.36M | 19.01 | 13.44M | 0% | +$0 | 3.59 | |
Bvf Inc Il | $61.75M | 8.3 | 5.87M | 0% | +$0 | 0.45 | |
Redmile Group | $58.5M | 7.87 | 5.56M | -3.96% | -$2.41M | 2.17 | |
Morgan Stanley | $53.77M | 7.23 | 5.11M | +5.14% | +$2.63M | <0.01 | |
BlackRock | $43.09M | 5.79 | 4.1M | +4.39% | +$1.81M | <0.01 | |
Helm Capital Management LLC | $36.56M | 4.92 | 3.48M | 0% | +$0 | 1.08 | |
The Vanguard Group | $25.86M | 3.48 | 2.46M | +2.65% | +$666,894.40 | <0.0001 | |
Credit Suisse | $19.94M | 2.68 | 1.9M | -17.7% | -$4.29M | 0.02 | |
Farallon Capital | $16.84M | 2.26 | 1.6M | -8.83% | -$1.63M | 0.12 | |
Samsara Biocapital Llc | $15.35M | 2.06 | 1.46M | 0% | +$0 | 2.39 | |
Acadian Asset Management | $13.72M | 1.85 | 1.31M | +4.07% | +$536,695.38 | 0.05 | |
Tang Capital Management, LLC | $11.57M | 1.56 | 1.1M | 0% | +$0 | 0.05 | |
Perceptive Advisors | $11.31M | 1.52 | 1.07M | 0% | +$0 | 0.01 | |
Citadel Advisors LLC | $11.2M | 1.51 | 1.06M | +513.57% | +$9.38M | 0.01 | |
State Street | $11.03M | 1.48 | 1.05M | +4.06% | +$430,478.41 | <0.0001 | |
Deutsche Bank | $9.35M | 1.26 | 889,250 | +0.07% | +$6,469.80 | <0.01 | |
Jacobs Levy Equity Management | $7.54M | 1.01 | 716,482 | +94.67% | +$3.67M | 0.03 | |
Bridgeway Capital Management | $7.39M | 0.99 | 702,683 | +3.29% | +$235,300.83 | 0.14 | |
Geode Capital Management | $7.04M | 0.95 | 668,984 | +4.58% | +$308,362.21 | <0.01 | |
Granahan Investment Management | $6.91M | 0.93 | 656,607 | -6.27% | -$462,364.54 | 0.24 | |
Healthcare Of Ontario Pension Plan Trust Fund | $6.3M | 0.85 | 599,000 | New | +$6.3M | 0.02 | |
Arrowstreet Capital, Limited Partnership | $6.12M | 0.82 | 581,558 | +58.45% | +$2.26M | 0.01 | |
AQR Capital | $5.15M | 0.69 | 489,502 | -28.66% | -$2.07M | 0.01 | |
Jupiter Fund Management | $4.49M | 0.6 | 426,944 | -13.85% | -$722,071.62 | 0.01 | |
PLATINUM INVESTMENT MANAGEMENT LTD | $4.4M | 0.59 | 418,376 | +2.08% | +$89,809.25 | 0.06 | |
Northern Trust | $4.4M | 0.59 | 418,248 | +0.26% | +$11,593.04 | <0.01 | |
Prosight Management Lp | $4.32M | 0.58 | 410,948 | New | +$4.32M | 1.2 | |
Silvercrest Asset Management Group Inc | $4.13M | 0.56 | 393,021 | +4.57% | +$180,659.96 | 0.03 | |
Dimensional Fund Advisors | $3.31M | 0.45 | 314,564 | -8.08% | -$290,888.58 | <0.01 | |
Empowered Funds Llc | $3.11M | 0.42 | 295,783 | +8.18% | +$235,300.83 | 0.06 | |
BNY Mellon | $3.1M | 0.42 | 294,878 | +6.49% | +$189,138.98 | <0.01 | |
Monaco Asset Management Sam | $3.08M | 0.41 | 292,500 | -16.43% | -$604,900.00 | 1.42 | |
Wellington Management Company | $3.01M | 0.41 | 286,595 | +39.63% | +$855,791.37 | <0.01 | |
Picton Mahoney Asset Management | $2.99M | 0.4 | 284,378 | -20.32% | -$763,082.15 | 0.14 | |
Goldman Sachs | $2.85M | 0.38 | 270,546 | +34.85% | +$735,611.02 | <0.01 | |
O Shaughnessy Asset Management Llc | $2.69M | 0.36 | 255,497 | +51.45% | +$913,104.29 | 0.03 | |
Wells Fargo | $2.51M | 0.34 | 238,687 | +0.18% | +$4,639.32 | <0.01 | |
Invesco | $2.43M | 0.33 | 231,181 | +304.92% | +$1.83M | <0.01 | |
Tejara Capital Ltd | $2.21M | 0.3 | 210,212 | -17.75% | -$477,218.71 | 0.75 | |
Nuveen | $2.14M | 0.29 | 203,516 | +4.38% | +$89,777.67 | <0.01 | |
Federated Hermes | $1.9M | 0.26 | 180,547 | +45,263.57% | +$1.9M | <0.01 | |
Assenagon Asset Management S.A. | $1.75M | 0.24 | 166,549 | New | +$1.75M | 0.01 | |
Qube Research & Technologies | $1.69M | 0.23 | 160,299 | +143.21% | +$992,972.00 | <0.01 | |
Kennedy Capital Management Inc | $1.62M | 0.22 | 154,362 | -1.07% | -$17,589.44 | 0.03 | |
Allspring Global Investments | $1.51M | 0.2 | 143,215 | -37.08% | -$887,993.32 | <0.01 | |
Ameriprise Financial | $1.49M | 0.2 | 141,793 | +15.35% | +$198,480.92 | <0.0001 | |
Charles Schwab | $1.32M | 0.18 | 125,491 | 0% | +$0 | <0.0001 | |
Renaissance Technologies | $1.22M | 0.16 | 115,600 | +686.39% | +$1.06M | <0.01 | |
Franklin Templeton Investments | $1.2M | 0.16 | 114,458 | +159.06% | +$739,303.42 | <0.0001 | |
Dz Bank Ag Deutsche Zentral Genossenschafts Bank Frankfurt Am Main | $1.04M | 0.14 | 99,064 | +15.35% | +$138,716.68 | <0.01 |