ALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for patients fighting cancer. Its lead product candidate is ALX148, a CD47 blocking therapeutic that is in Phase 1b/2 clinical trial used for the treatment of myelodysplastic syndromes; and for the treatment of acute myeloid leukemia and non-Hodgkin's lymphoma, as well as a range of solid tumor indications, including head and neck squamous cell carcinoma, human epidermal growth factor receptor 2 (HER2) positive gastric/gastroesophageal junction carcinoma, HER2-expressing breast cancer, and other solid tumors. The company's pre-clinical products include ALTA-002, a SIRPa TRAAC that offers ways to engage the innate and adaptive immune response to cancer. ALX Oncology Holdings Inc. has a collaboration agreement with Merck for a Phase 2 trial evaluating ALX148 in combination with pembrolizumab with and without chemotherapy in patients with head and neck cancer; Zymeworks on a Phase 1 trial evaluating ALX148 with the HER2-targeting bispecific antibody zanidatamab in patients with HER2-expressing breast cancer and other solid tumors; and Tallac Therapeutics for the development, manufacturing and commercialization of a novel class of cancer immunotherapeutics. It also has a license agreement with Selexis SA and Crystal Bioscience, Inc. The company was founded in 2015 and is headquartered in South San Francisco, California.
Over the last 12 months, insiders at ALX Oncology Holdings Inc. have bought $152,110 and sold $1.95M worth of ALX Oncology Holdings Inc. stock.
On average, over the past 5 years, insiders at ALX Oncology Holdings Inc. have bought $78.24M and sold $11.27M worth of stock each year.
Highest buying activity among insiders over the last 12 months: GARCIA PETER S (Chief Financial Officer) — $204,677. Lettmann Jason (CHIEF EXECUTIVE OFFICER) — $49,771.
The last purchase of 12,000 shares for transaction amount of $102,338 was made by GARCIA PETER S (CHIEF FINANCIAL OFFICER) on 2024‑06‑13.
2024-06-13 | GARCIA PETER S | CHIEF FINANCIAL OFFICER | 12,000 0.0229% | $8.53 | $102,338 | -18.48% | ||
2024-06-04 | Sale | Pons Jaume | PRESIDENT & CSO | 20,000 0.0387% | $8.43 | $168,652 | -1.49% | |
2024-05-13 | Sale | Randolph Sophia | CHIEF MEDICAL OFFICER | 12,000 0.0243% | $15.94 | $191,339 | -42.39% | |
2024-05-06 | Sale | Pons Jaume | PRESIDENT & CSO | 20,000 0.0399% | $15.92 | $318,334 | -32.60% | |
2024-04-16 | Sale | Pons Jaume | PRESIDENT & CSO | 50,000 0.0977% | $14.20 | $710,195 | -1.66% | |
2024-04-04 | Sale | Pons Jaume | PRESIDENT & CSO | 20,000 0.0396% | $11.15 | $223,036 | +20.15% | |
2024-03-14 | Lettmann Jason | CHIEF EXECUTIVE OFFICER | 4,400 0.0085% | $11.31 | $49,771 | +10.04% | ||
2024-01-04 | Sale | Pinto Shelly | SVP, Finance and CAO | 2,717 0.0057% | $13.60 | $36,957 | +7.72% | |
2023-12-29 | Sale | Pons Jaume | President & CSO | 7,179 0.0144% | $15.04 | $107,972 | -5.16% | |
2023-12-29 | Sale | Randolph Sophia | Chief Medical Officer | 3,128 0.0063% | $15.04 | $47,045 | -5.16% | |
2023-12-29 | Sale | GARCIA PETER S | Chief Financial Officer | 1,893 0.0038% | $15.04 | $28,471 | -5.16% | |
2023-12-29 | Sale | Pinto Shelly | SVP, Finance and CAO | 1,631 0.0033% | $15.04 | $24,530 | -5.16% | |
2023-07-06 | Sale | Pinto Shelly | VP, Finance and CAO | 7,345 0.0185% | $6.52 | $47,889 | +50.39% | |
2023-06-30 | Sale | Pons Jaume | President & CEO | 3,208 0.0077% | $7.34 | $23,547 | +25.37% | |
2023-06-30 | Sale | Randolph Sophia | Chief Medical Officer | 1,605 0.0038% | $7.34 | $11,781 | +25.37% | |
2023-06-30 | Sale | Pinto Shelly | VP, Finance and CAO | 466 0.0011% | $7.34 | $3,420 | +25.37% | |
2023-06-30 | Sale | GARCIA PETER S | Chief Financial Officer | 887 0.0021% | $7.34 | $6,511 | +25.37% | |
2022-12-29 | Sale | Pons Jaume | President & CEO | 3,232 0.0077% | $11.07 | $35,779 | -40.71% | |
2022-12-29 | Sale | Randolph Sophia | Chief Medical Officer | 1,617 0.0038% | $11.07 | $17,901 | -40.71% | |
2022-12-29 | Sale | Pinto Shelly | VP, Finance and CAO | 482 0.0011% | $11.07 | $5,336 | -40.71% |
Pons Jaume | President & CSO | 604205 1.2412% | $5.88 | 0 | 15 | |
Randolph Sophia | Chief Medical Officer | 330349 0.627% | $5.88 | 0 | 13 | |
Lettmann Jason | 171620 0.574% | $5.88 | 2 | 4 | +90.48% | |
GARCIA PETER S | Chief Financial Officer | 122348 0.1713% | $5.88 | 2 | 8 | +90.48% |
Pinto Shelly | SVP, Finance and CAO | 78591 0.1578% | $5.88 | 0 | 5 | |
Adelman Robert J | 5268325 10.575% | $5.88 | 1 | 0 | +90.48% | |
Graham G. Walmsley | director | 995000 1.9972% | $5.88 | 2 | 0 | +34.88% |
GOODMAN COREY S | 850000 1.7062% | $5.88 | 1 | 0 | +90.48% | |
Vivo Capital IX, LLC | 10 percent owner | 789474 1.5847% | $5.88 | 1 | 0 | +90.48% |
LSV Associates, LLC | 10 percent owner | 285956 0.574% | $5.88 | 1 | 4 | +90.48% |
Hemrajani Rekha | director | 3000 0.006% | $5.88 | 1 | 0 | +90.48% |
Pietzke Steffen | VP Fin & Chief Acct Officer | 3000 0.006% | $5.88 | 1 | 0 | +90.48% |
venBio | $108.15M | 18.62 | 9.7M | 0% | +$0 | 38.37 | |
Fidelity Investments | $83.88M | 14.44 | 7.52M | +0.67% | +$557,399.65 | 0.01 | |
Redmile Group | $48.24M | 8.3 | 4.33M | +18.23% | +$7.44M | 1.79 | |
Vivo Capital | $47.05M | 8.1 | 4.22M | 0% | +$0 | 4.14 | |
Cormorant Asset Management Lp | $35.03M | 6.03 | 3.14M | 0% | +$0 | 1.66 | |
OrbiMed | $30.31M | 5.22 | 2.72M | -12.18% | -$4.2M | 0.62 | |
BlackRock | $24.77M | 4.26 | 2.22M | -0.6% | -$150,881.80 | <0.01 | |
The Vanguard Group | $17.47M | 3.01 | 1.57M | +4.26% | +$714,213.19 | <0.0001 | |
Bioimpact Capital Llc | $14.14M | 2.44 | 1.27M | +0.29% | +$41,388.80 | 2.29 | |
Citadel Advisors LLC | $13.77M | 2.37 | 1.24M | +0.17% | +$23,504.20 | 0.01 | |
Geode Capital Management | $6.74M | 1.16 | 604,714 | +3.36% | +$219,460.15 | <0.01 | |
State Street | $6.18M | 1.06 | 553,867 | +10.44% | +$583,936.65 | <0.0001 | |
Morgan Stanley | $3.83M | 0.66 | 343,137 | -17.07% | -$787,814.29 | <0.0001 | |
Northern Trust | $2.73M | 0.47 | 245,212 | +0.56% | +$15,297.80 | <0.0001 | |
Renaissance Technologies | $2.61M | 0.45 | 234,100 | -13.46% | -$405,826.57 | <0.01 | |
T. Rowe Price | $2.6M | 0.45 | 232,769 | -57.15% | -$3.46M | <0.0001 | |
Charles Schwab | $2.34M | 0.4 | 209,759 | +0.77% | +$17,784.25 | <0.01 | |
Federated Hermes | $2.25M | 0.39 | 201,362 | +2.46% | +$53,809.92 | 0.01 | |
Adage Capital Partners Gp L L C | $1.78M | 0.31 | 160,000 | 0% | +$0 | <0.01 | |
Goldman Sachs | $1.75M | 0.3 | 157,002 | +73.02% | +$738,787.72 | <0.0001 | |
Wellington Management Company | $1.42M | 0.24 | 127,037 | +57.44% | +$516,791.51 | <0.0001 | |
Marshall Wace | $1.36M | 0.23 | 121,546 | +950.62% | +$1.23M | <0.01 | |
Squarepoint Ops LLC | $1.19M | 0.2 | 106,356 | New | +$1.19M | 0.01 | |
Nuveen | $1.18M | 0.2 | 105,894 | 0% | +$0 | <0.0001 | |
Los Angeles Capital Management LLC | $1.1M | 0.19 | 98,960 | -19.82% | -$272,729.00 | <0.01 | |
BNY Mellon | $889,402.00 | 0.15 | 79,767 | -7.58% | -$72,909.85 | <0.0001 | |
Standard Life | $738,253.00 | 0.13 | 66,211 | 0% | +$0 | <0.01 | |
Two Sigma | $729,823.00 | 0.13 | 65,455 | -0.71% | -$5,195.90 | <0.01 | |
Millennium Management LLC | $671,119.00 | 0.12 | 60,190 | New | +$671,119.00 | <0.0001 | |
The Manufacturers Life Insurance Company | $670,327.00 | 0.12 | 60,119 | +25.09% | +$134,469.03 | <0.01 | |
Hrt Financial Llc | $659,000.00 | 0.11 | 59,186 | New | +$659,000.00 | <0.01 | |
Jane Street Capital | $660,024.00 | 0.11 | 59,195 | +35.77% | +$173,906.48 | <0.01 | |
State of Wisconsin Investment Board | $606,181.00 | 0.1 | 54,366 | New | +$606,181.00 | <0.01 | |
Dimensional Fund Advisors | $561,303.00 | 0.1 | 50,341 | -62.49% | -$935,274.57 | <0.0001 | |
RhumbLine Advisers | $555,931.00 | 0.1 | 49,860 | +3.54% | +$19,021.63 | <0.01 | |
Td Asset Management Inc | $546,350.00 | 0.09 | 49,000 | -30.4% | -$238,610.00 | <0.0001 | |
Bank of America | $525,779.00 | 0.09 | 47,155 | -27.18% | -$196,251.43 | <0.0001 | |
Swiss National Bank | $492,830.00 | 0.09 | 44,200 | New | +$492,830.00 | <0.0001 | |
Citigroup | $485,103.00 | 0.08 | 43,507 | +817.29% | +$432,218.55 | <0.0001 | |
Nan Fung Group | $467,743.00 | 0.08 | 41,950 | 0% | +$0 | 0.51 | |
JPMorgan Chase | $467,152.00 | 0.08 | 41,897 | -11.95% | -$63,398.96 | <0.0001 | |
DekaBank | $468,000.00 | 0.08 | 41,000 | 0% | +$0 | <0.01 | |
AllianceBernstein | $432,509.00 | 0.07 | 38,790 | -3.72% | -$16,725.02 | <0.0001 | |
Walleye Capital | $426,387.00 | 0.07 | 38,241 | -50.87% | -$441,417.20 | <0.01 | |
Martingale Asset Management L P | $403,575.00 | 0.07 | 36,195 | -14.04% | -$65,941.22 | 0.01 | |
Cwm Advisors Llc | $369,689.00 | 0.06 | 33,156 | New | +$369,689.00 | 0.04 | |
Financial Advisory Group | $350,300.00 | 0.06 | 31,417 | 0% | +$0 | 0.06 | |
American Century Investments | $330,742.00 | 0.06 | 29,663 | +39.95% | +$94,406.92 | <0.0001 | |
UBS | $324,175.00 | 0.06 | 29,074 | -6.18% | -$21,341.09 | <0.0001 | |
Connor Clark & Lunn Investment Management Ltd | $324,287.00 | 0.06 | 29,084 | +118.53% | +$175,891.47 | <0.01 |