| $385M | ||
| $337M | ||
| $100M | ||
| $87M | ||
| $82M | ||
| $62M |
Buys | $10,110 | 1 | 100 |
Sells | $0 | 0 | 0 |
| Gilad Oren | President/CEO | 1 | $10,110 | 0 | $0 | $10,110 |
Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel cancer therapeutics that target DNA damage response pathways. Its lead product candidate is ATRN-119, an oral ATR inhibitor that is in phase 1/2a clinical trial to treat patients with advanced solid tumors. The company's products pipeline also includes ATRN-Backup, an ATR inhibitor; ATRN-W1051 to treat anti-tumor activity; and ATRN-DDRi. Aprea Therapeutics, Inc. is based in Boston, Massachusetts.
Over the last 12 months, insiders at Aprea Therapeutics, Inc. have bought $10,110 and sold $0 worth of Aprea Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Aprea Therapeutics, Inc. have bought $111,657 and sold $1.41M worth of stock each year.
Highest buying activity among insiders over the last 12 months: Gilad Oren (President/CEO) — $10,110.
The last purchase of 5,500 shares for transaction amount of $10,110 was made by Gilad Oren (President/CEO) on 2025‑04‑03.
| 2025-04-03 | Gilad Oren | President/CEO | 5,500 0.1023% | $1.84 | $10,110 | -11.67% | ||
| 2024-10-23 | Gilad Oren | President/CEO | 500 0.0086% | $3.92 | $1,958 | -53.33% | ||
| 2024-10-18 | Sale | Duey Marc | director | 6,462 0.1238% | $4.58 | $29,583 | -58.18% | |
| 2024-10-16 | Duey Marc | director | 30,000 0.8303% | $4.39 | $131,700 | -47.29% | ||
| 2024-10-15 | Gilad Oren | President/CEO | 250 0.0046% | $2.90 | $725 | -39.18% | ||
| 2024-10-14 | Gilad Oren | President/CEO | 1,000 0.0163% | $2.59 | $2,590 | -27.34% | ||
| 2024-10-14 | Duey Marc | director | 190 0.0031% | $2.58 | $490 | -27.34% | ||
| 2024-10-11 | Seizinger Bernd R. | director | 10,000 0.169% | $2.68 | $26,800 | -28.08% | ||
| 2024-10-11 | Hamill John P. | SrVP/CFO/Prin Fin & Acct Ofcr | 50 0.0008% | $2.46 | $123 | -28.08% | ||
| 2024-10-10 | Gilad Oren | President/CEO | 150 0.0024% | $2.54 | $381 | -26.18% | ||
| 2024-10-10 | Hamill John P. | SrVP/CFO/Prin Fin & Acct Ofcr | 450 0.0074% | $2.61 | $1,175 | -26.18% | ||
| 2024-03-13 | Gilad Oren | President, CEO | 2,000 0.0683% | $7.29 | $14,580 | -31.44% | ||
| 2024-03-13 | Seizinger Bernd R. | director | 6,860 0.2342% | $7.29 | $50,009 | -31.44% | ||
| 2024-03-13 | Hamill John P. | SrVP/CFO/Prin Fin & Acct Ofcr | 1,010 0.0345% | $7.29 | $7,363 | -31.44% | ||
| 2024-03-13 | HENNEMAN JOHN B III | director | 6,860 0.2342% | $7.29 | $50,009 | -31.44% | ||
| 2023-06-07 | Seizinger Bernd R. | director | 6,029 0.1917% | $3.68 | $22,192 | +18.87% | ||
| 2023-06-06 | Seizinger Bernd R. | director | 4,068 0.1208% | $3.63 | $14,764 | +11.20% | ||
| 2020-12-28 | Sale | Redmile Group, LLC | 10 percent owner | 500,000 2.4014% | $5.58 | $2.79M | -11.73% | |
| 2020-10-05 | Sale | 5AM Ventures IV, L.P. | Former 10% holder | 175,000 0.7844% | $25.30 | $4.43M | -80.91% | |
| 2020-07-07 | Sale | KDev Investments AB | 10 percent owner | 241,703 1.1593% | $34.55 | $8.35M | -79.65% |
| Gilad Oren | President/CEO | 345620 5.6631% | $366,357.20 | 6 | 0 | <0.0001% |
| Christenson Johan | director | 2366104 38.7696% | $2.51M | 1 | 0 | +53.58% |
| HealthCap VII, L.P. | 10 percent owner | 2366104 38.7696% | $2.51M | 1 | 0 | +53.58% |
| KDev Investments AB | 10 percent owner | 1992586 32.6494% | $2.11M | 0 | 2 | |
| Redmile Group, LLC | 10 percent owner | 1768718 28.9812% | $1.87M | 1 | 1 | +53.58% |
| Versant Vantage I, L.P. | 10 percent owner | 333333 5.4618% | $353,332.98 | 1 | 0 | +53.58% |
| Versant V Luxco S.a r.l. | 10 percent owner | 333333 5.4618% | $353,332.98 | 1 | 0 | +53.58% |
| Duey Marc | director | 233651 3.8285% | $247,670.06 | 2 | 1 | <0.0001% |
| 5AM Ventures IV, L.P. | Former 10% holder | 138497 2.2693% | $146,806.82 | 1 | 4 | +53.58% |
| ROCKLAGE SCOTT M | Former 10% holder | 75965 1.2447% | $80,522.90 | 0 | 3 | |
| Seizinger Bernd R. | director | 44730 0.7329% | $47,413.80 | 4 | 0 | <0.0001% |
| Hamill John P. | SrVP/CFO/Prin Fin & Acct Ofcr | 19368 0.3174% | $20,530.08 | 3 | 0 | <0.0001% |
| HENNEMAN JOHN B III | director | 8139 0.1334% | $8,627.34 | 2 | 0 | +11.07% |
| Magni Guido | director | 6500 0.1065% | $6,890.00 | 1 | 0 | +53.58% |
| SCHADE CHRISTIAN S | President & CEO | 5000 0.0819% | $5,300.00 | 1 | 0 | +53.58% |
| Coiante Scott M | SVP, Chief Financial Officer | 2500 0.041% | $2,650.00 | 1 | 0 | +53.58% |
| Korbel Gregory Alan | VP of Business Dev't | 500 0.0082% | $530.00 | 1 | 0 | +53.58% |
| Attar Eyal C. | SVP, Chief Medical Officer | 200 0.0033% | $212.00 | 1 | 0 | +53.58% |
$22,360,243 | 40 | 22.92% | $4.97M | |
$13,664,154 | 40 | -70.35% | $7.07M | |
$1,029,337 | 36 | -28.38% | $6.62M | |
$1,138,733 | 28 | -4.94% | $4.39M | |
Aprea Therapeutics, Inc. (APRE) | $29,635,355 | 27 | 9.05% | $6.47M |
$547,862 | 19 | -29.82% | $7.89M | |
$1,556,551 | 15 | -25.43% | $7.4M | |
$20,715,938 | 10 | -42.51% | $6.17M | |
$120,379 | 10 | -24.48% | $7.45M | |
$90,087 | 9 | 20.06% | $6.67M | |
$8,971,546 | 8 | 6.18% | $5.61M | |
$84,058 | 7 | -61.66% | $7.11M | |
$159,974 | 7 | -18.60% | $7.61M | |
$76,299 | 4 | 11.60% | $6.47M | |
$149,778 | 4 | -45.16% | $4.38M | |
$4,423 | 2 | 3.27% | $6.04M | |
$19,863 | 1 | 144.27% | $4.63M | |
$739,010 | 1 | 3.33% | $4.56M | |
$75,000 | 1 | -30.67% | $5.09M |
| Increased Positions | 7 | +26.92% | 17,932 | +0.99% |
| Decreased Positions | 8 | -30.77% | 214,589 | -11.82% |
| New Positions | 2 | New | 12,269 | New |
| Sold Out Positions | 2 | Sold Out | 14,966 | Sold Out |
| Total Postitions | 25 | -3.85% | 2M | -10.83% |
| Aigh Capital Management Llc | $680.00 | 8.99% | 539,300 | 0 | 0% | 2025-09-30 |
| Sphera Funds Management Ltd. | $340.00 | 4.5% | 270,000 | 0 | 0% | 2025-09-30 |
| Nantahala Capital Management, Llc | $259.00 | 3.43% | 205,760 | 0 | 0% | 2025-09-30 |
| Vanguard Group Inc | $199.00 | 2.64% | 158,238 | -15,604 | -8.98% | 2025-09-30 |
| Dafna Capital Management Llc | $173.00 | 2.29% | 137,174 | 0 | 0% | 2025-09-30 |
| Sio Capital Management, Llc | $141.00 | 1.87% | 112,223 | -167,146 | -59.83% | 2025-09-30 |
| Morgan Stanley | $83.00 | 1.1% | 65,808 | +2,477 | +3.91% | 2025-09-30 |
| Geode Capital Management, Llc | $56.00 | 0.74% | 44,616 | +1,479 | +3.43% | 2025-09-30 |
| Bnp Paribas Financial Markets | $22.00 | 0.29% | 17,132 | +1,700 | +11.02% | 2025-09-30 |
| Lpl Financial Llc | $20.00 | 0.27% | 16,052 | -1,000 | -5.86% | 2025-09-30 |