Aprea Therapeutics, Inc. (APRE)
Trading
Quantity
Profitability
Ownership
Largest Insider Buys in Sector
APRE Insider Trading Activity
APRE Median Price and Trade Amounts History Chart
Statistics of Insider Transactions
Amount of Insider Buys and Sells
Buys | $176,052 | 10 | 91 |
Sells | $29,583 | 1 | 9 |
Related Transactions
| Duey Marc | director | 2 | $132,190 | 1 | $29,583 | $102,607 |
| Seizinger Bernd R. | director | 1 | $26,800 | 0 | $0 | $26,800 |
| Gilad Oren | President/CEO | 5 | $15,764 | 0 | $0 | $15,764 |
| Hamill John P. | SrVP/CFO/Prin Fin & Acct Ofcr | 2 | $1,298 | 0 | $0 | $1,298 |
About Aprea Therapeutics, Inc.
Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel cancer therapeutics that target DNA damage response pathways. Its lead product candidate is ATRN-119, an oral ATR inhibitor that is in phase 1/2a clinical trial to treat patients with advanced solid tumors. The company's products pipeline also includes ATRN-Backup, an ATR inhibitor; ATRN-W1051 to treat anti-tumor activity; and ATRN-DDRi. Aprea Therapeutics, Inc. is based in Boston, Massachusetts.
Insider Activity of Aprea Therapeutics, Inc.
Over the last 12 months, insiders at Aprea Therapeutics, Inc. have bought $176,052 and sold $29,583 worth of Aprea Therapeutics, Inc. stock.
On average, over the past 5 years, insiders at Aprea Therapeutics, Inc. have bought $167,485 and sold $31.43M worth of stock each year.
Highest buying activity among insiders over the last 12 months: Duey Marc (director) — $132,190. Seizinger Bernd R. (director) — $26,800. Gilad Oren (President/CEO) — $15,764.
The last purchase of 5,500 shares for transaction amount of $10,110 was made by Gilad Oren (President/CEO) on 2025‑04‑03.
List of Insider Buy and Sell Transactions, Aprea Therapeutics, Inc.
| 2025-04-03 | Gilad Oren | President/CEO | 5,500 0.1023% | $1.84 | $10,110 | -1.18% | ||
| 2024-10-23 | Gilad Oren | President/CEO | 500 0.0086% | $3.92 | $1,958 | -14.36% | ||
| 2024-10-18 | Sale | Duey Marc | director | 6,462 0.1238% | $4.58 | $29,583 | -23.86% | |
| 2024-10-16 | Duey Marc | director | 30,000 0.8303% | $4.39 | $131,700 | -4.10% | ||
| 2024-10-15 | Gilad Oren | President/CEO | 250 0.0046% | $2.90 | $725 | +10.26% | ||
| 2024-10-14 | Gilad Oren | President/CEO | 1,000 0.0163% | $2.59 | $2,590 | +31.11% | ||
| 2024-10-14 | Duey Marc | director | 190 0.0031% | $2.58 | $490 | +31.11% | ||
| 2024-10-11 | Seizinger Bernd R. | director | 10,000 0.169% | $2.68 | $26,800 | +28.85% | ||
| 2024-10-11 | Hamill John P. | SrVP/CFO/Prin Fin & Acct Ofcr | 50 0.0008% | $2.46 | $123 | +28.85% | ||
| 2024-10-10 | Gilad Oren | President/CEO | 150 0.0024% | $2.54 | $381 | +31.89% | ||
| 2024-10-10 | Hamill John P. | SrVP/CFO/Prin Fin & Acct Ofcr | 450 0.0074% | $2.61 | $1,175 | +31.89% | ||
| 2024-03-13 | Gilad Oren | President, CEO | 2,000 0.0683% | $7.29 | $14,580 | -31.53% | ||
| 2024-03-13 | Seizinger Bernd R. | director | 6,860 0.2342% | $7.29 | $50,009 | -31.53% | ||
| 2024-03-13 | Hamill John P. | SrVP/CFO/Prin Fin & Acct Ofcr | 1,010 0.0345% | $7.29 | $7,363 | -31.53% | ||
| 2024-03-13 | HENNEMAN JOHN B III | director | 6,860 0.2342% | $7.29 | $50,009 | -31.53% | ||
| 2023-06-07 | Seizinger Bernd R. | director | 6,029 0.1917% | $3.68 | $22,192 | +18.87% | ||
| 2023-06-06 | Seizinger Bernd R. | director | 4,068 0.1208% | $3.63 | $14,764 | +11.20% | ||
| 2020-12-28 | Sale | Redmile Group, LLC | 10 percent owner | 500,000 2.4014% | $5.58 | $2.79M | -11.73% | |
| 2020-10-05 | Sale | 5AM Ventures IV, L.P. | Former 10% holder | 175,000 0.7844% | $25.30 | $4.43M | -80.91% | |
| 2020-07-07 | Sale | KDev Investments AB | 10 percent owner | 241,703 1.1593% | $34.55 | $8.35M | -79.65% |
Insider Historical Profitability
| Gilad Oren | President/CEO | 345620 6.2932% | $587,554.00 | 6 | 0 | <0.0001% |
| Duey Marc | director | 233651 4.2544% | $397,206.70 | 2 | 1 | |
| Seizinger Bernd R. | director | 44730 0.8145% | $76,041.00 | 4 | 0 | <0.0001% |
| Hamill John P. | SrVP/CFO/Prin Fin & Acct Ofcr | 19368 0.3527% | $32,925.60 | 3 | 0 | <0.0001% |
| Christenson Johan | director | 2366104 43.0831% | $4.02M | 1 | 0 | +53.58% |
Historical Insider Profitability vs. Competitors
$8,253,997 | 122 | -53.40% | $7.28M | |
$8,900,811 | 57 | -24.79% | $10.21M | |
$95,303,339 | 30 | -13.78% | $9.58M | |
$523,320 | 24 | 94.37% | $8.94M | |
$746,223 | 23 | -7.24% | $7.5M |
APRE Institutional Investors: Active Positions
| Increased Positions | 10 | +47.62% | 87,793 | +4.39% |
| Decreased Positions | 5 | -23.81% | 11,500 | -0.57% |
| New Positions | 5 | New | 64,455 | New |
| Sold Out Positions | <1 | Sold Out | 899 | Sold Out |
| Total Postitions | 26 | +23.81% | 2M | +3.81% |
APRE Ownership Change vs Market
Institutional Investor Ownership
| Aigh Capital Management Llc | $1,127.00 | 10.79% | 539,300 | 0 | 0% | 2024-12-31 |
| Sio Capital Management, Llc | $578.00 | 5.53% | 276,603 | 0 | 0% | 2024-12-31 |
| Sphera Funds Management Ltd. | $564.00 | 5.4% | 270,000 | 0 | 0% | 2024-12-31 |
| Nantahala Capital Management, Llc | $430.00 | 4.12% | 205,760 | 0 | 0% | 2024-12-31 |
| Vanguard Group Inc | $363.00 | 3.48% | 173,842 | 0 | 0% | 2024-12-31 |
| Stonepine Capital Management, Llc | $312.00 | 2.98% | 149,221 | +12,047 | +8.78% | 2024-12-31 |
| Dafna Capital Management Llc | $287.00 | 2.74% | 137,174 | 0 | 0% | 2024-12-31 |
| Exome Asset Management Llc | $267.00 | 2.56% | 127,960 | -9,214 | -6.72% | 2024-12-31 |
| Geode Capital Management, Llc | $89.00 | 0.85% | 42,663 | +2,596 | +6.48% | 2024-12-31 |
| Morgan Stanley | $77.00 | 0.74% | 36,808 | +2,600 | +7.6% | 2024-12-31 |