Axsome Therapeutics, Inc. (AXSM) Insider Trading Activity

NASDAQ$206.68
Market Cap
$10.64B
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
244 of 853
Rank in Industry
144 of 492

AXSM Insider Trading Activity

AXSM Median Price and Trade Amounts History Chart

Statistics of Insider Transactions

Amount of Insider Buys and Sells

Buys
$200,466
1
2
Sells
$152,480,825
40
98

Related Transactions

Coleman Markdirector
1
$200,466
5
$8.21M
$-8.01M
JEFFS ROGERdirector
0
$0
2
$141,656
$-141,656
Mahony Susandirector
0
$0
2
$145,017
$-145,017
Maizel AriChief Commercial Officer
0
$0
2
$2.75M
$-2.75M
Saad Mark Edirector
0
$0
2
$6.32M
$-6.32M
Pizzie NickChief Financial Officer
0
$0
2
$10.18M
$-10.18M
Jacobson Mark L.Chief Operating Officer
0
$0
6
$15.3M
$-15.3M
TABUTEAU HERRIOTChief Executive Officer
0
$0
20
$110.58M
$-110.58M

About Axsome Therapeutics, Inc.

Axsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer's disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation. AXS-07, a novel, orally administered, rapidly-acting investigational medicine that employs multiple mechanisms of action. It has concluded two Phase III studies for the acute treatment of migraine attacks. AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is presently undergoing a Phase III trial for narcolepsy. AXS-14, an oral investigational drug, advancing through Phase III trials for the management of fibromyalgia. Axsome Therapeutics also engages in a research collaboration with Duke University to further assess AXS-05's potential in smoking cessation. The company, established in 2012, has its main offices in New York, New York.

Insider Activity of Axsome Therapeutics, Inc.

Over the last 12 months, insiders at Axsome Therapeutics, Inc. have bought $200,466 and sold $152.48M worth of Axsome Therapeutics, Inc. stock.

On average, over the past 5 years, insiders at Axsome Therapeutics, Inc. have bought $272,797 and sold $64.19M worth of stock each year.

Highest buying activity among insiders over the last 12 months: Coleman Mark (director) — $200,466.

The last purchase of 1,575 shares for transaction amount of $200,466 was made by Coleman Mark (director) on 2025‑09‑08.

List of Insider Buy and Sell Transactions, Axsome Therapeutics, Inc.

2026-09-03SaleJacobson Mark L.Chief Operating Officer
10,000
0.0195%
$208.65
$2.09M
-0.80%
2026-08-06SaleTABUTEAU HERRIOTChief Executive Officer
4,660
0.0092%
$213.95
$997,007
-0.85%
2026-08-05SaleTABUTEAU HERRIOTChief Executive Officer
45,004
0.0871%
$212.01
$9.54M
-1.75%
2026-07-01SaleTABUTEAU HERRIOTChief Executive Officer
49,666
0.0947%
$240.25
$11.93M
-9.78%
2026-06-11SaleJEFFS ROGERdirector
286
0.0006%
$249.12
$71,248
-9.68%
2026-06-10SaleJEFFS ROGERdirector
286
0.0006%
$246.18
$70,407
-6.43%
2026-06-10SaleColeman Markdirector
643
0.0013%
$249.00
$160,107
-6.43%
2026-06-10SaleMahony Susandirector
300
0.0006%
$246.18
$73,854
-6.43%
2026-06-09SalePizzie NickChief Financial Officer
33,000
0.0655%
$240.09
$7.92M
-5.64%
2026-06-09SaleTABUTEAU HERRIOTChief Executive Officer
49,670
0.0989%
$241.01
$11.97M
-5.64%
2026-06-09SaleMahony Susandirector
300
0.0006%
$237.21
$71,163
-5.64%
2026-06-02SaleColeman Markdirector
5,537
0.0104%
$223.39
$1.24M
+4.62%
2026-06-01SaleColeman Markdirector
6,000
0.0117%
$230.30
$1.38M
+0.90%
2026-05-29SaleColeman Markdirector
6,000
0.0116%
$233.46
$1.4M
-1.04%
2026-05-05SaleJacobson Mark L.Chief Operating Officer
233
0.0005%
$228.18
$53,166
+3.91%
2026-05-04SaleJacobson Mark L.Chief Operating Officer
4,517
0.009%
$227.94
$1.03M
+3.55%
2026-04-22SaleMaizel AriChief Commercial Officer
7,500
0.0143%
$182.42
$1.37M
+22.55%
2026-02-26SaleColeman Markdirector
25,000
0.049%
$161.11
$4.03M
+32.20%
2026-02-26SaleJacobson Mark L.Chief Operating Officer
35,378
0.0696%
$161.88
$5.73M
+32.20%
2026-02-02SaleTABUTEAU HERRIOTChief Executive Officer
32,410
0.0642%
$185.60
$6.02M
+13.05%
Total: 87
*Gray background shows transactions not older than one year

Insider Historical Profitability

51.12%
JEFFS ROGERdirector
58367
0.1134%
$12.06M110
+3.44%
Pizzie NickChief Financial Officer
42867
0.0833%
$8.86M64
+84.72%
Coleman Markdirector
30389
0.0591%
$6.28M811
+51.01%
Saad Mark Edirector
10002
0.0194%
$2.07M23
+23.86%
TABUTEAU HERRIOTChief Executive Officer
7229
0.014%
$1.49M020
Mahony Susandirector
829
0.0016%
$171,337.7202
Jacobson Mark L.Chief Operating Officer
0
0%
$0012
Maizel AriChief Commercial Officer
0
0%
$002
Kaye RandallChief Medical Officer
6022
0.0117%
$1.24M10
<0.0001%
Murdock Hunter R.General Counsel
0
0%
$005
*Gray background shows insiders who have made transactions during last year

Historical Insider Profitability vs. Competitors

$159,914,414
243
18.52%
$12.07B
$273,531,368
93
38.24%
$12.5B
$2,765,836
72
20.00%
$12.86B
$108,876,545
67
72.81%
$13.07B
$19,233,721
36
70.14%
$14.83B
$1,801,511
23
18.58%
$12.16B
$415,090,639
19
-14.04%
$14.66B
$11,859,102
17
18.62%
$9.05B
Axsome Therapeutics, Inc.
(AXSM)
$1,279,017
16
51.12%
$10.64B
$118,094,211
15
38.32%
$9.66B
$627,701,115
15
145.68%
$14.04B
$9,976,473
12
29.52%
$9.81B
$762,720
11
52.96%
$9.65B
$11,898,979
10
54.58%
$10.56B
$35,908,794
10
126.31%
$9.37B
$55,713,031
8
-0.36%
$8.46B
$948,235
8
15.54%
$11.34B
$2,246,813
6
70.15%
$8.57B
$41,376,000
4
-12.07%
$8.83B

AXSM Institutional Investors: Active Positions

Increased Positions229+60.58%6M+16.06%
Decreased Positions164-43.39%6M-15.35%
New Positions86New2MNew
Sold Out Positions36Sold Out2MSold Out
Total Postitions443+17.2%38M+0.71%

AXSM Ownership Change vs Market

Institutional Investor Ownership

Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
Active Shareholders
Vanguard Group Inc$747,040.008.36%4.18M+235,626+5.97%2025-09-30
Blackrock, Inc.$677,401.007.58%3.79M-44,061-1.15%2025-09-30
Wellington Management Group Llp$238,473.002.67%1.33M+609,516+84.07%2025-09-30
Rtw Investments, Lp$199,933.002.24%1.12M-398,020-26.24%2025-09-30
Macquarie Group Ltd$193,796.002.17%1.08M-53,212-4.68%2025-09-30
Price T Rowe Associates Inc /Md/$185,382.002.08%1.04M+424,705+69.31%2025-09-30
Geode Capital Management, Llc$178,279.002%997,700+8,247+0.83%2025-09-30
Invesco Ltd.$177,003.001.98%990,557+419,008+73.31%2025-09-30
State Street Corp$168,498.001.89%942,960-15,543-1.62%2025-09-30
Fmr Llc$165,803.001.86%927,883-48,847-5%2025-09-30

Financial Ratios

Summary
Comparison with Competitors

Price to Earnings

Price/Earnings to Growth

Price to Sales

Price to Book

Price/Free Cash Flow

Analyst Recommendations

Analyst Price Targets

Prismo does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.
Information is provided 'as-is' and solely for informational purposes and is not advice. Prismo does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.