Axsome Therapeutics, Inc. (AXSM) Insider Trading Activity

NASDAQ$185.96
Market Cap
$9.37B
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
264 of 893
Rank in Industry
146 of 511

AXSM Insider Trading Activity

AXSM Median Price and Trade Amounts History Chart

Statistics of Insider Transactions

Amount of Insider Buys and Sells

Buys
$200,466
1
2
Sells
$113,556,487
40
98

Related Transactions

Coleman Markdirector
1
$200,466
3
$1.11M
$-905,382
Maizel AriChief Commercial Officer
0
$0
1
$1.38M
$-1.38M
Murdock Hunter R.General Counsel
0
$0
5
$3.65M
$-3.65M
Pizzie NickChief Financial Officer
0
$0
3
$4.21M
$-4.21M
Saad Mark Edirector
0
$0
2
$6.32M
$-6.32M
JEFFS ROGERdirector
0
$0
6
$13.37M
$-13.37M
Jacobson Mark L.Chief Operating Officer
0
$0
5
$13.39M
$-13.39M
TABUTEAU HERRIOTChief Executive Officer
0
$0
15
$70.13M
$-70.13M

About Axsome Therapeutics, Inc.

Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's product pipeline includes AXS-05, a therapeutic for the treatment of major depressive disorder and resistant depression disorders; and that is in the Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation. It is also developing AXS-07, a novel, oral, rapidly absorbed, multi-mechanistic, and investigational medicine that has completed two Phase III trials for the acute treatment of migraine; AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is in Phase III trial to treat narcolepsy; and AXS-14, a novel, oral, and investigational medicine that is in Phase III trial for the treatment of fibromyalgia. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.

Insider Activity of Axsome Therapeutics, Inc.

Over the last 12 months, insiders at Axsome Therapeutics, Inc. have bought $200,466 and sold $113.56M worth of Axsome Therapeutics, Inc. stock.

On average, over the past 5 years, insiders at Axsome Therapeutics, Inc. have bought $287,335 and sold $41.81M worth of stock each year.

Highest buying activity among insiders over the last 12 months: Coleman Mark (director) — $200,466.

The last purchase of 1,575 shares for transaction amount of $200,466 was made by Coleman Mark (director) on 2025‑09‑08.

List of Insider Buy and Sell Transactions, Axsome Therapeutics, Inc.

2026-01-22SalePizzie NickChief Financial Officer
12,000
0.0239%
$187.92
$2.26M
-1.04%
2026-01-21SaleMaizel AriChief Commercial Officer
7,500
0.0145%
$184.44
$1.38M
+0.82%
2026-01-07SaleTABUTEAU HERRIOTChief Executive Officer
31,261
0.0619%
$170.38
$5.33M
+1.75%
2026-01-06SaleTABUTEAU HERRIOTChief Executive Officer
29,450
0.0587%
$172.33
$5.08M
+0.83%
2026-01-05SaleTABUTEAU HERRIOTChief Executive Officer
78,703
0.1559%
$171.28
$13.48M
+2.64%
2025-12-31SaleSaad Mark Edirector
31,346
0.069%
$165.18
$5.18M
-4.42%
2025-12-04SaleTABUTEAU HERRIOTChief Executive Officer
10,558
0.021%
$148.18
$1.56M
+4.50%
2025-12-03SaleTABUTEAU HERRIOTChief Executive Officer
20,163
0.0398%
$146.94
$2.96M
+4.49%
2025-12-02SaleTABUTEAU HERRIOTChief Executive Officer
49,252
0.0994%
$144.59
$7.12M
+8.52%
2025-11-05SaleTABUTEAU HERRIOTChief Executive Officer
21,775
0.0435%
$134.49
$2.93M
+10.13%
2025-11-04SaleTABUTEAU HERRIOTChief Executive Officer
50,459
0.1002%
$133.79
$6.75M
+10.69%
2025-11-03SaleTABUTEAU HERRIOTChief Executive Officer
91,705
0.1802%
$132.34
$12.14M
+9.95%
2025-10-08SaleTABUTEAU HERRIOTChief Executive Officer
12,774
0.0256%
$118.84
$1.52M
+24.30%
2025-10-07SaleTABUTEAU HERRIOTChief Executive Officer
13,390
0.0269%
$118.77
$1.59M
+24.34%
2025-10-06SaleTABUTEAU HERRIOTChief Executive Officer
19,220
0.0386%
$120.17
$2.31M
+22.96%
2025-09-22SaleJacobson Mark L.Chief Operating Officer
10,000
0.0198%
$115.96
$1.16M
+23.89%
2025-09-16SaleTABUTEAU HERRIOTChief Executive Officer
19,719
0.0395%
$114.19
$2.25M
+25.60%
2025-09-16SaleJacobson Mark L.Chief Operating Officer
45,783
0.0921%
$114.48
$5.24M
+25.60%
2025-09-15SaleTABUTEAU HERRIOTChief Executive Officer
15,254
0.0307%
$117.37
$1.79M
+22.20%
2025-09-12SaleTABUTEAU HERRIOTChief Executive Officer
27,907
0.0562%
$118.96
$3.32M
+19.99%
Total: 67
*Gray background shows transactions not older than one year

Insider Historical Profitability

51.12%
JEFFS ROGERdirector
57510
0.1141%
$10.69M18
+3.44%
Coleman Markdirector
48212
0.0956%
$8.97M86
+51.01%
Pizzie NickChief Financial Officer
42588
0.0845%
$7.92M63
+84.72%
Saad Mark Edirector
10002
0.0198%
$1.86M23
+23.86%
TABUTEAU HERRIOTChief Executive Officer
7229
0.0143%
$1.34M015
Jacobson Mark L.Chief Operating Officer
0
0%
$008
Murdock Hunter R.General Counsel
0
0%
$005
Maizel AriChief Commercial Officer
0
0%
$001
Kaye RandallChief Medical Officer
6022
0.0119%
$1.12M10
<0.0001%
*Gray background shows insiders who have made transactions during last year

Historical Insider Profitability vs. Competitors

$211,610,344
91
38.45%
$10.91B
$2,765,836
72
20.00%
$10.8B
$108,876,545
67
72.81%
$8.14B
$88,307,390
38
-1.70%
$10.25B
$19,233,721
36
70.14%
$11.87B
$1,801,511
23
18.58%
$9.11B
$415,090,639
19
-14.04%
$15.01B
$11,859,102
17
18.62%
$7.75B
$103,944,213
17
5.95%
$6.87B
Axsome Therapeutics, Inc.
(AXSM)
$1,279,017
16
51.12%
$9.37B
$627,701,115
15
145.68%
$12.28B
$9,976,473
12
29.52%
$6.59B
$284,820
10
45.67%
$13B
$11,898,979
10
54.58%
$8.16B
$55,713,031
8
-0.36%
$6.35B
$948,235
8
15.56%
$10.62B
$105,414,951
5
10.07%
$7.74B
$41,376,000
4
-12.07%
$6.9B
$36,900,000
3
-9.12%
$10.94B

AXSM Institutional Investors: Active Positions

Increased Positions201+58.43%5M+12.48%
Decreased Positions144-41.86%5M-12.72%
New Positions55New534,156New
Sold Out Positions38Sold Out535,318Sold Out
Total Postitions401+16.57%38M-0.24%

AXSM Ownership Change vs Market

Institutional Investor Ownership

Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
Active Shareholders
Vanguard Group Inc$747,040.008.36%4.18M+235,626+5.97%2025-09-30
Blackrock, Inc.$677,401.007.58%3.79M-44,061-1.15%2025-09-30
Wellington Management Group Llp$238,473.002.67%1.33M+609,516+84.07%2025-09-30
Rtw Investments, Lp$199,933.002.24%1.12M-398,020-26.24%2025-09-30
Macquarie Group Ltd$193,796.002.17%1.08M-53,212-4.68%2025-09-30
Price T Rowe Associates Inc /Md/$185,382.002.08%1.04M+424,705+69.31%2025-09-30
Geode Capital Management, Llc$178,279.002%997,700+8,247+0.83%2025-09-30
Invesco Ltd.$177,003.001.98%990,557+419,008+73.31%2025-09-30
State Street Corp$168,498.001.89%942,960-15,543-1.62%2025-09-30
Fmr Llc$165,803.001.86%927,883-48,847-5%2025-09-30

Financial Ratios

Summary
Comparison with Competitors

Price to Earnings

Price/Earnings to Growth

Price to Sales

Price to Book

Price/Free Cash Flow

Analyst Recommendations

Analyst Price Targets

Prismo does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.
Information is provided 'as-is' and solely for informational purposes and is not advice. Prismo does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.