KPTI Logo

Karyopharm Therapeutics Inc. (KPTI) 

NASDAQ$6.75
Market Cap
$56.81M
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
668 of 924
Rank in Industry
380 of 527

KPTI Insider Trading Activity

KPTI Median Price and Trade Amounts History Chart

Statistics of Insider Transactions

Amount of Insider Buys and Sells

Buys
$000
Sells
$1,529,03825100

Related Transactions

Cheng Sohanya RoshanEVP & Chief Commercial Officer0$01$3,866$-3,866
Mason MichaelEVP, CFO & Treasurer0$02$5,734$-5,734
Poulton StuartEVP, Chief Development Officer0$02$6,782$-6,782
Rangwala ReshmaEVP & Chief Medical Officer0$01$7,943$-7,943
Mano MichaelSVP, General Counsel&Secretary0$02$20,434$-20,434
Paulson Richard A.President and CEO0$011$36,562$-36,562
PAKIANATHAN DEEPIKAdirector0$06$1.45M$-1.45M

About Karyopharm Therapeutics Inc.

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. The company discovers, develops, and commercializes novel and Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1. Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma, in combination with â€¦

Insider Activity of Karyopharm Therapeutics Inc.

Over the last 12 months, insiders at Karyopharm Therapeutics Inc. have bought $0 and sold $1.53M worth of Karyopharm Therapeutics Inc. stock.

On average, over the past 5 years, insiders at Karyopharm Therapeutics Inc. have bought $130,090 and sold $2.6M worth of stock each year.

There was no buying activity among insiders over the last 12 months.

The last purchase of 41,140 shares for transaction amount of $49,985 was made by BOHLIN GAREN G (director) on 2023‑09‑12.

List of Insider Buy and Sell Transactions, Karyopharm Therapeutics Inc.

2025-03-04SaleMano MichaelSVP, General Counsel&Secretary
2,793
0.0333%
$6.29$17,568+8.24%
2025-02-18SalePoulton StuartEVP, Chief Development Officer
5,914
0.0048%
$0.63$3,726-19.52%
2025-02-04SalePaulson Richard A.President and CEO
4,099
0.0034%
$0.65$2,664-5.48%
2025-01-06SalePaulson Richard A.President and CEO
4,055
0.0031%
$0.78$3,175-25.00%
2024-12-04SalePaulson Richard A.President and CEO
3,620
0.003%
$0.81$2,932-18.29%
2024-11-05SalePaulson Richard A.President and CEO
3,675
0.0029%
$0.91$3,346-20.57%
2024-10-04SalePaulson Richard A.President and CEO
3,607
0.0036%
$0.88$3,172-20.96%
2024-09-04SalePaulson Richard A.President and CEO
3,667
0.003%
$0.72$2,647+2.43%
2024-09-04SaleCheng Sohanya RoshanEVP & Chief Commercial Officer
5,356
0.0044%
$0.72$3,866+2.43%
2024-09-04SaleMason MichaelEVP, CFO & Treasurer
7,050
0.0057%
$0.72$5,089+2.43%
2024-09-04SaleMano MichaelSVP, General Counsel&Secretary
3,971
0.0032%
$0.72$2,866+2.43%
2024-08-06SalePaulson Richard A.President and CEO
3,608
0.0032%
$0.93$3,355-10.71%
2024-07-30SalePoulton StuartEVP, Chief Development Officer
2,883
0.0023%
$1.06$3,056-28.11%
2024-07-05SalePaulson Richard A.President and CEO
3,616
0.0025%
$0.85$3,077-5.05%
2024-06-07SalePAKIANATHAN DEEPIKAdirector
2,240
0.0018%
$0.95$2,130-16.88%
2024-06-06SalePAKIANATHAN DEEPIKAdirector
118,452
0.096%
$0.98$116,415-17.85%
2024-06-05SalePAKIANATHAN DEEPIKAdirector
468,044
0.3619%
$0.96$448,480-19.57%
2024-06-04SalePaulson Richard A.President and CEO
3,592
0.0033%
$0.99$3,556-13.73%
2024-06-04SaleMason MichaelEVP, CFO & Treasurer
652
0.0006%
$0.99$645-13.73%
2024-06-04SalePAKIANATHAN DEEPIKAdirector
341,040
0.2976%
$0.95$324,704-13.73%
Total: 371
*Gray background shows transactions not older than one year

Insider Historical Profitability

2.08%
PAKIANATHAN DEEPIKAdirector
0
0%
$057+36.66%
Frenkel RanEVP, Chief Dev. Officer
168290
1.9996%
$1.14M29<0.0001%
Shah JatinEVP, Chief Medical Officer
129450
1.5381%
$873,787.5016<0.0001%
Brannelly PaulSVP, FINANCE & ADMIN, TREAS
66136
0.7858%
$446,418.0030+28.23%
BOHLIN GAREN Gdirector
45140
0.5364%
$304,695.0020<0.0001%
*Gray background shows insiders who have made transactions during last year

Historical Insider Profitability vs. Competitors

$6,787,959
35
49.84%
$60.62M
$459,011,221
33
33.04%
$57.94M
$144,247,213
29
10.15%
$64.24M
$2,239,226
28
3.41%
$63.36M
$26,736,140
20
-18.64%
$54.85M

KPTI Institutional Investors: Active Positions

Increased Positions34+28.81%681,637+17.18%
Decreased Positions44-37.29%587,793-14.82%
New Positions14New191,230New
Sold Out Positions21Sold Out122,214Sold Out
Total Postitions108-8.47%4M+2.37%

KPTI Ownership Change vs Market

Institutional Investor Ownership

Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
Active Shareholders
Vanguard Group Inc$4,057.006.38%510,32400%2024-12-31
Adage Capital Partners Gp, L.L.C.$3,350.005.27%421,344+133,340+46.3%2024-12-31
Palo Alto Investors Lp$2,601.004.09%327,150-13,013-3.83%2024-12-31
Blackrock, Inc.$1,998.003.14%251,271+8,700+3.59%2024-12-31
Morgan Stanley$1,862.002.93%234,224+225,980+2,741.14%2024-12-31
Citadel Advisors Llc$1,645.002.59%206,92200%2024-12-31
Marshall Wace, Llp$1,273.002%160,102+21,280+15.33%2024-12-31
Catalio Capital Management, Lp$1,237.001.95%155,633+155,633New2024-12-31
Eversept Partners, Lp$1,107.001.74%139,257-230,620-62.35%2024-12-31
Avidity Partners Management Lp$1,070.001.68%134,57300%2024-12-31

Financial Ratios

Summary
Comparison with Competitors

Analyst Recommendations

Analyst Price Targets

Prismo does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.
Information is provided 'as-is' and solely for informational purposes and is not advice. Prismo does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.